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    Bead reader
    1.
    发明授权
    Bead reader 有权
    珠读者

    公开(公告)号：US08927294B2

    公开(公告)日：2015-01-06

    申请号：US12954955

    申请日：2010-11-29

    Applicant: Boaz Ran ,  Chanan Sluszny ,  Shay Nimri

    Inventor： Boaz Ran ,  Chanan Sluszny ,  Shay Nimri

    IPC: G01N21/00 ,  G01N21/76 ,  G01N21/64 ,  G01N21/78 ,  G01N35/00 ,  G01N15/06 ,  G01N15/14 ,  G01N35/10

    CPC classification number: G01N21/76 ,  G01N15/0612 ,  G01N15/1463 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/78 ,  G01N35/0098 ,  G01N2015/1486 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2035/1046 ,  Y10T436/25

    Abstract: A method of determining a normalized quantity of an analyte adhering to beads in a detection area of a bead-based assaying system, the method comprising: a) causing a complex of the analyte to fluorescently or chemically emit a first light, or to release a dye; b) measuring an integrated intensity of the first light emitted from the beads in the detection area, or a concentration of the dye released from the beads in the detection area, or both; c) causing light to interact with the beads in the detection area, the interaction not depending on whether or how much analyte is adhering to the beads; d) measuring a second light resulting from the interaction with the beads which does not depend on the analyte; and e) determining the normalized quantity of analyte from the integrated intensity of the first light or concentration of the dye or both, and from the measured second light.

    Abstract translation: 一种确定在珠基测定系统的检测区域中附着于珠的分析物的归一化量的方法，所述方法包括：a）使分析物的复合物荧光或化学发射第一光，或释放 染料; b）测量从检测区域中的珠子发射的第一光的集成强度或从检测区域中的珠粒释放的染料的浓度，或两者; c）使光与检测区域中的珠粒相互作用，相互作用不取决于是否或多少分析物粘附到珠粒上; d）测量与不依赖于分析物的珠的相互作用产生的第二光; 以及e）根据所述第一光的积分强度或所述染料或两者的浓度以及所测量的第二光确定归一化的分析物量。

    BEAD READER
    2.
    发明申请
    BEAD READER 有权
    珠读卡器

    公开(公告)号：US20110136250A1

    公开(公告)日：2011-06-09

    申请号：US12954955

    申请日：2010-11-29

    Applicant: Boaz RAN ,  Chanan Sluszny ,  Shay Nimri

    Inventor： Boaz RAN ,  Chanan Sluszny ,  Shay Nimri

    IPC: G01N21/00 ,  G01J1/58 ,  G01N21/75 ,  G01N1/00

    CPC classification number: G01N21/76 ,  G01N15/0612 ,  G01N15/1463 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/78 ,  G01N35/0098 ,  G01N2015/1486 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2035/1046 ,  Y10T436/25

    Abstract: A method of determining a normalized quantity of an analyte adhering to beads in a detection area of a bead-based assaying system, the method comprising: a) causing a complex of the analyte to fluorescently or chemically emit a first light, or to release a dye; b) measuring an integrated intensity of the first light emitted from the beads in the detection area, or a concentration of the dye released from the beads in the detection area, or both; c) causing light to interact with the beads in the detection area, the interaction not depending on whether or how much analyte is adhering to the beads; d) measuring a second light resulting from the interaction with the beads which does not depend on the analyte; and e) determining the normalized quantity of analyte from the integrated intensity of the first light or concentration of the dye or both, and from the measured second light.

    Abstract translation: 一种确定在珠基测定系统的检测区域中附着于珠的分析物的归一化量的方法，所述方法包括：a）使分析物的复合物荧光或化学发射第一光，或释放 染料; b）测量从检测区域中的珠子发射的第一光的集成强度或从检测区域中的珠粒释放的染料的浓度，或两者; c）使光与检测区域中的珠粒相互作用，相互作用不取决于是否或多少分析物粘附到珠粒上; d）测量与不依赖于分析物的珠的相互作用产生的第二光; 以及e）根据所述第一光的积分强度或所述染料或两者的浓度以及所测量的第二光确定归一化的分析物量。

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