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公开(公告)号：US08858593B2
公开(公告)日：2014-10-14
申请号：US13354227
申请日：2012-01-19
申请人： Charles W. Kerber
发明人： Charles W. Kerber
CPC分类号： A61B17/0057 , A61B2017/00623 , A61B2017/00884 , A61B2017/00889 , A61B2017/00893 , A61B2017/00898 , A61B2090/033
摘要： An emergency medical device and method is provided for treatment of open wounds by enhancing clotting and arresting hemorrhaging, particularly in the area of the neck, abdomen, chest or groin. The devices includes an elongated delivery tube for insertion into a wound cavity and subsequent delivery of a space filling, sponge-like mass containing a polymerizable liquid sealant that polymerizes upon contact with body fluids after which the delivery tube is removed.
摘要翻译： 提供了一种紧急医疗装置和方法，用于通过增强凝血和阻止出血来治疗开放性伤口，特别是在颈部，腹部，胸部或腹股沟区域。 这些装置包括用于插入到伤口腔中的细长输送管，随后输送包含可聚合液体密封剂的空间填充海绵状物质，所述可聚合液体密封剂在与体液接触之后聚合，之后移出输送管。
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公开(公告)号：USRE39150E1
公开(公告)日：2006-06-27
申请号：US09823775
申请日：2001-03-30
IPC分类号： A61K31/275 , A61K31/12 , A61K31/05 , A61K33/24 , A61K33/42
CPC分类号： A61L24/001 , A61K31/05 , A61K31/122 , A61K33/24 , A61L24/06 , A61L2430/36 , C09J4/00 , Y10S514/824 , Y10S514/834 , Y10S514/93 , Y10S514/944 , Y10S514/97 , A61K2300/00 , C08L35/04 , C08F222/32
摘要： A composition including 2-hexyl cyanoacrylate and goal is useful in treating arteriovenous malformations (AVMs) and other body lumens to be blocked.
摘要翻译： 包括氰基丙烯酸2-己基酯和目标物的组合物可用于治疗动静脉畸形（AVM）和其他体腔被阻断。
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公开(公告)号：US4029104A
公开(公告)日：1977-06-14
申请号：US664503
申请日：1976-03-08
申请人： Charles W. Kerber
发明人： Charles W. Kerber
CPC分类号： A61B6/504 , A61M25/0075 , A61M25/0125 , A61M25/10 , A61B6/481 , A61M2025/0018 , A61M2025/0042
摘要： This is an extremely small and flexible flow guided balloon catheter for use in small and tortuous blood vessels in body organs such as the brain or kidney, for diagnostic angiography. In order to attain such small size and extreme flexibility, a single lumen in the catheter tube serves the dual purpose of inflating the balloon and injecting a liquid into the blood vessel. This is accomplished by arranging the balloon to extend beyond the end of the catheter tube and providing a calibrated orifice in the distal end of the balloon to maintain inflation pressure in the balloon while the liquid is being discharged through the orifice.
摘要翻译： 这是一种非常小且灵活的流动导向气囊导管，用于身体器官如脑或肾中的小而曲折的血管，用于诊断性血管造影。 为了获得如此小的尺寸和极大的柔韧性，导管管中的单个内腔用于充气球囊并将液体注射到血管中的双重目的。 这是通过将球囊布置成超过导管管的端部并且在球囊的远端提供校准的孔口来实现的，以在液体通过孔排出液体时保持球囊中的充气压力。
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公开(公告)号：US20090246262A1
公开(公告)日：2009-10-01
申请号：US12411780
申请日：2009-03-26
申请人： Charles W. Kerber
发明人： Charles W. Kerber
IPC分类号： A61K9/70 , A61K31/785 , A61P17/02
CPC分类号： A61L15/24 , A61K31/785 , A61L15/58 , A61L24/06 , A61L26/0014 , A61L31/048 , C08L35/04
摘要： A method for treating wounds by adhering a wound dressing to a wound with a polymerizable alkyl cyanoacrylate composition, such that the wound dressing and cyanoacrylate composition seal the wound to inhibit bleeding and infection. The dressing may be in the form of a mitten. Also disclosed is injection of polymerizable cyanoacrylate into puncture wounds to seal the wounds and inhibit bleeding.
摘要翻译： 一种通过用可聚合的氰基丙烯酸烷基酯组合物将伤口敷料粘附到伤口上来治疗伤口的方法，使得伤口敷料和氰基丙烯酸酯组合物密封伤口以抑制出血和感染。 敷料可以是手套的形式。 还公开了将可聚合的氰基丙烯酸酯注射到穿刺伤口中以密封伤口并抑制出血。
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公开(公告)号：US06476070B2
公开(公告)日：2002-11-05
申请号：US09497075
申请日：2000-02-02
IPC分类号： A61K3126
CPC分类号： C09J4/00 , A61K33/24 , A61L24/06 , A61L31/048 , Y10S514/97 , C08F222/32 , A61K2300/00 , C08L35/04
摘要： A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified fatty acid and an opacificant agent where said composition forms a resultant aggregate structure when said composition contacts an anionic environment. The compositions are useful for filling, occluding, partially filling or partially occluding an unfilled volume or space in a mass in an anionic environment. The composition are also useful for ablating diseased or undesired tissue by cutting off the blood supply to the tissue.
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公开(公告)号：US20130089505A1
公开(公告)日：2013-04-11
申请号：US13544420
申请日：2012-07-09
IPC分类号： A61K31/785 , A61K49/04 , A61K49/22 , A61K49/06
CPC分类号： A61K31/785 , A61K49/04 , A61K49/0404 , A61K49/06 , A61K49/22 , A61L24/001 , A61L24/06 , A61L2430/36 , C08L35/04
摘要： Alkyl cyanoacrylate compositions and methods for making those compositions, utilizing high purity monomeric starting materials, formed into more viscous oligomers, and combined with a plasticizer and inhibitor to provide a single-container, storage stable medical cyanoacrylate.
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公开(公告)号：US20090257976A1
公开(公告)日：2009-10-15
申请号：US12268318
申请日：2008-11-10
IPC分类号： A61K31/785 , C07C255/08
CPC分类号： A61K31/785 , A61K49/04 , A61K49/0404 , A61K49/06 , A61K49/22 , A61L24/001 , A61L24/06 , A61L2430/36 , C08L35/04
摘要： Alkyl cyanoacrylate compositions and methods for making those compositions, utilizing high purity monomeric starting materials, formed into more viscous oligomers, and combined with a plasticizer and inhibitor to provide a single-container, storage stable medical cyanoacrylate.
摘要翻译： 氰基丙烯酸烷基酯组合物和使用高纯度单体原料制备这些组合物的方法，形成更粘稠的低聚物，并与增塑剂和抑制剂组合以提供单容器，储存稳定的医用氰基丙烯酸酯。
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公开(公告)号：US06538026B1
公开(公告)日：2003-03-25
申请号：US09577115
申请日：2000-05-23
IPC分类号： A61K3126
CPC分类号： C08F267/06 , A61K31/05 , A61K31/12 , A61K31/275 , A61K31/78 , A61K31/785 , A61K33/24 , A61L24/06 , A61L31/048 , C09J4/00 , C09J4/06 , A61K2300/00 , C08L35/04 , C08F222/32
摘要： A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed from an alkyl cyanoacrylate monomer, an alkyl esterified fatty acid and an opacificant agent where said composition forms a resultant aggregate structure when said composition contacts an anionic environment. The compositions are useful for filling, occluding, partially filling or partially occluding an unfilled volume or space in a mass in an anionic environment. The composition are also useful for ablating diseased or undesired tissue by cutting off the blood supply to the tissue.
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公开(公告)号：US20120191129A1
公开(公告)日：2012-07-26
申请号：US13354227
申请日：2012-01-19
申请人： Charles W. Kerber
发明人： Charles W. Kerber
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00623 , A61B2017/00884 , A61B2017/00889 , A61B2017/00893 , A61B2017/00898 , A61B2090/033
摘要： An emergency medical device and method is provided for treatment of open wounds by enhancing clotting and arresting hemorrhaging, particularly in the area of the neck, abdomen, chest or groin. The devices includes an elongated delivery tube for insertion into a wound cavity and subsequent delivery of a space filling, sponge-like mass containing a polymerizable liquid sealant that polymerizes upon contact with body fluids after which the delivery tube is removed.
摘要翻译： 提供了一种紧急医疗装置和方法，用于通过增强凝血和阻止出血来治疗开放性伤口，特别是在颈部，腹部，胸部或腹股沟区域。 这些装置包括用于插入到伤口腔中的细长输送管，随后输送包含可聚合液体密封剂的空间填充海绵状物质，所述可聚合液体密封剂在与体液接触之后聚合，之后移出输送管。
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公开(公告)号：US20090137981A1
公开(公告)日：2009-05-28
申请号：US12276807
申请日：2008-11-24
申请人： Charles W. Kerber
发明人： Charles W. Kerber
IPC分类号： A61K31/785 , A61M25/10
CPC分类号： A61B17/12022 , A61B17/00491 , A61B17/12109 , A61B17/12113 , A61B17/12136 , A61B17/12186 , A61B17/12195 , A61L24/06 , C08L35/04
摘要： Described herein are methods for treating a blood vessel. In an embodiment, the method of treating a blood vessel comprises providing at least one manipulable tool in a blood vessel, depositing a non-solid polymerizable material into a deposition area of the vessel, wherein the polymerizable liquid hardens over time upon contact with blood in the blood vessel, and altering the shape of the polymerizable material while it hardens by manipulating the tool.
摘要翻译： 本文描述了治疗血管的方法。 在一个实施方案中，治疗血管的方法包括在血管中提供至少一个可操作的工具，将非固体可聚合材料沉积到血管的沉积区域中，其中可聚合液体在与血液接触时随时间变硬 血管，并且通过操作该工具而使可聚合材料的形状变化。
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