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公开(公告)号：US07244393B2
公开(公告)日：2007-07-17
申请号：US10026415
申请日：2001-12-21
IPC分类号： G01N33/48
CPC分类号： B01L3/5023 , B01L3/502723 , B01L2200/0642 , B01L2200/16 , B01L2300/048 , B01L2300/0654 , B01L2300/069 , B01L2300/0803 , B01L2300/0809 , B01L2300/0825 , B01L2300/0861 , B01L2300/0864 , B01L2400/0406 , B01L2400/0688 , G01N21/4788
摘要： Diagnostic devices, systems and methods for detecting the presence of an analyte in a sample are provided. In one embodiment, the device comprises a substrate, a binder printed in a pattern onto a surface of the substrate, and a means for directing a sample towards the surface of the substrate that is printed with the binder. Systems of the present invention further include a light source that can be directed through the aforementioned means or another opening to the binder-printed surface to test for diffraction.
摘要翻译： 提供用于检测样品中分析物的存在的诊断装置，系统和方法。 在一个实施例中，该装置包括基板，以图案印刷到基板的表面上的粘合剂，以及用于将样品朝向印刷有粘合剂的基材的表面引导的装置。 本发明的系统还包括可以通过上述装置或粘合剂印刷表面的另一个开口引导的光源以测试衍射。
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公开(公告)号：US08377379B2
公开(公告)日：2013-02-19
申请号：US11640435
申请日：2006-12-15
申请人： Shawn R. Feaster , Kaiyuan Yang , Ning Wei , Chibueze O. Chidebelu-Eze , James M. Takeuchi , Rosann M. Kaylor , Enrico L. DiGiammarino , Jeffrey E. Fish
发明人： Shawn R. Feaster , Kaiyuan Yang , Ning Wei , Chibueze O. Chidebelu-Eze , James M. Takeuchi , Rosann M. Kaylor , Enrico L. DiGiammarino , Jeffrey E. Fish
IPC分类号： G01N30/96
CPC分类号： B01L3/5023 , A61B5/150022 , A61B5/150343 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150717 , A61B5/150824 , A61B5/15105 , A61B5/15113 , A61B5/15117 , A61B5/15186 , A61B5/1519 , A61B5/157 , B01L2200/0605 , B01L2200/16 , B01L2300/0672 , B01L2300/0867 , B01L2400/0683 , G01N33/491
摘要： A lateral flow assay device includes a housing, and a test strip disposed within the housing having a membrane with a detection region and a collection region. A sample meter includes a first end for absorption of a test sample, and a storage section that receives and stores at least a component of the test sample. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed adjacent the collection region of the membrane. The test sample component is transferable from the storage section to the collection region for subsequent migration to the detection region. An activatable isolation mechanism is provided within the housing and is disposed so as to isolate portions of the sample meter storage section upon activation thereof such that a defined length of the storage section is presented to the collection region of the membrane.
摘要翻译： 侧流测定装置包括壳体和设置在壳体内的测试条，其具有带有检测区域和收集区域的膜。 样品计量器包括用于吸收测试样品的第一端和接收并存储至少测试样品的组分的存储部分。 壳体中的开口的尺寸用于将样品计量器插入到壳体中，使得样品计量器的存储部分邻近膜的收集区域设置。 测试样本组件可从存储部分转移到收集区域，以便随后迁移到检测区域。 在壳体内提供可激活的隔离机构，并且被设置成在启动时分离样品计量存储部分的部分，使得存储部分的限定长度被呈现给膜的收集区域。
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公开(公告)号：US20080145272A1
公开(公告)日：2008-06-19
申请号：US11640435
申请日：2006-12-15
申请人： Shawn R. Feaster , Kaiyuan Yang , Ning Wei , Chibueze O. Chidebelu-Eze , James M. Takeuchi , Rosann M. Kaylor , Enrico L. DiGiammarino , Jeffrey E. Fish
发明人： Shawn R. Feaster , Kaiyuan Yang , Ning Wei , Chibueze O. Chidebelu-Eze , James M. Takeuchi , Rosann M. Kaylor , Enrico L. DiGiammarino , Jeffrey E. Fish
CPC分类号： B01L3/5023 , A61B5/150022 , A61B5/150343 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150717 , A61B5/150824 , A61B5/15105 , A61B5/15113 , A61B5/15117 , A61B5/15186 , A61B5/1519 , A61B5/157 , B01L2200/0605 , B01L2200/16 , B01L2300/0672 , B01L2300/0867 , B01L2400/0683 , G01N33/491
摘要： A lateral flow assay device includes a housing, and a test strip disposed within the housing having a membrane with a detection region and a collection region. A sample meter includes a first end for absorption of a test sample, and a storage section that receives and stores at least a component of the test sample. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed adjacent the collection region of the membrane. The test sample component is transferable from the storagesection to the collection region for subsequent migration to the detection region. An activatable isolation mechanism is provided within the housing and is disposed so as to isolate portions of the sample meter storage section upon activation thereof such that a defined length of the storage section is presented to the collection region of the membrane.
摘要翻译： 侧流测定装置包括壳体和设置在壳体内的测试条，其具有带有检测区域和收集区域的膜。 样品计量器包括用于吸收测试样品的第一端和接收并存储至少测试样品的组分的存储部分。 壳体中的开口的尺寸用于将样品计量器插入到壳体中，使得样品计量器的存储部分邻近膜的收集区域设置。 测试样品组分可以从储存区转移到收集区域，以便随后迁移到检测区域。 在壳体内提供可激活的隔离机构，并且被设置成在启动时分离样品计量存储部分的部分，使得存储部分的限定长度被呈现给膜的收集区域。
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公开(公告)号：US20100015658A1
公开(公告)日：2010-01-21
申请号：US12570713
申请日：2009-09-30
IPC分类号： C12Q1/02
CPC分类号： G01N33/54366 , B01L3/5023 , B01L2200/027 , B01L2300/0681 , B01L2300/0825 , B01L2300/0867 , B01L2400/0406 , B01L2400/0683 , G01N33/558 , Y10S436/825 , Y10T436/107497 , Y10T436/108331
摘要： A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.
摘要翻译： 提供了用于检测驻留在测试样品中的分析物的诊断方法和相关测试试剂盒。 套件包括壳体和设置在壳体内的膜，其具有检测区域和收集区域。 提供血样计，其具有用于吸收血液样本的第一端，与第一端相邻的过滤部分，其从血液样品中过滤红细胞成分，以及与过滤部相邻的存储部，其接收血浆或血清 从过滤部分。 壳体中的开口的尺寸适于将样品计量器插入壳体中，使得样品计量器的存储部分设置成与膜的收集区域流体连通。 将血浆或血清从样品计量器的储存部分转移到膜的收集区域，以便随后迁移到检测区域。
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公开(公告)号：US07618810B2
公开(公告)日：2009-11-17
申请号：US11300650
申请日：2005-12-14
IPC分类号： G01N21/00 , G01N15/06 , G01N33/53 , G01N31/00 , G01N33/543 , B01L3/00 , B01L3/02 , B01L11/00 , C12Q1/00 , C12M1/36 , C12M1/34 , C12M3/00
CPC分类号： G01N33/54366 , B01L3/5023 , B01L2200/027 , B01L2300/0681 , B01L2300/0825 , B01L2300/0867 , B01L2400/0406 , B01L2400/0683 , G01N33/558 , Y10S436/825 , Y10T436/107497 , Y10T436/108331
摘要： A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.
摘要翻译： 提供了用于检测驻留在测试样品中的分析物的诊断方法和相关测试试剂盒。 套件包括壳体和设置在壳体内的膜，其具有检测区域和收集区域。 提供血样计，其具有用于吸收血液样本的第一端，与第一端相邻的过滤部分，其从血液样品中过滤红细胞成分，以及与过滤部相邻的存储部，其接收血浆或血清 从过滤部分。 壳体中的开口的尺寸适于将样品计量器插入壳体中，使得样品计量器的存储部分设置成与膜的收集区域流体连通。 将血浆或血清从样品计量器的储存部分转移到膜的收集区域，以便随后迁移到检测区域。
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公开(公告)号：US07838258B2
公开(公告)日：2010-11-23
申请号：US12570713
申请日：2009-09-30
IPC分类号： G01N33/53 , G01N33/543
CPC分类号： G01N33/54366 , B01L3/5023 , B01L2200/027 , B01L2300/0681 , B01L2300/0825 , B01L2300/0867 , B01L2400/0406 , B01L2400/0683 , G01N33/558 , Y10S436/825 , Y10T436/107497 , Y10T436/108331
摘要： A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.
摘要翻译： 提供了用于检测驻留在测试样品中的分析物的诊断方法和相关测试试剂盒。 套件包括壳体和设置在壳体内的膜，其具有检测区域和收集区域。 提供血样计，其具有用于吸收血液样本的第一端，与第一端相邻的过滤部分，其从血液样品中过滤红细胞成分，以及与过滤部相邻的存储部，其接收血浆或血清 从过滤部分。 壳体中的开口的尺寸适于将样品计量器插入壳体中，使得样品计量器的存储部分设置成与膜的收集区域流体连通。 将血浆或血清从样品计量器的储存部分转移到膜的收集区域，以便随后迁移到检测区域。
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