-
公开(公告)号:US20050107611A1
公开(公告)日:2005-05-19
申请号:US10499146
申请日:2002-12-19
申请人: Barbara Matuszczak , Christa Muller
发明人: Barbara Matuszczak , Christa Muller
IPC分类号: A61K31/4985 , A61P1/18 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/06 , A61P11/08 , A61P11/16 , A61P13/12 , A61P17/02 , A61P25/00 , A61P25/08 , A61P25/16 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/36 , A61P37/04 , A61P37/08 , C07D487/04 , C07D487/14
CPC分类号: C07D487/04
摘要: The invention relates to derivatives of the pyrazoyl[1,2,4]triazolo[4,3-α]quinoxaline according to formula (1), or of its analog in the form of the pyrazolyl-substituted tetrazolo[1,5-α]quinoxalines according to formula (2). The substances according to formula 1 or 2, in this form or in the form of their pharmaceutically acceptable salts, are suitable as active agents, especially as adenosine receptor ligands.
摘要翻译: 本发明涉及式(1)的吡唑并[1,2,4]三唑并[4,3-a]喹喔啉的衍生物,或其吡唑基取代的四唑并[1,5-α ]喹喔啉。 根据式1或2的物质,以这种形式或其药学上可接受的盐的形式,适合作为活性剂,特别是作为腺苷受体配体。
-
公开(公告)号:US20070014028A1
公开(公告)日:2007-01-18
申请号:US11534022
申请日:2006-09-21
申请人: Johannes Wangler , Karl-Heinz Schuster , Alexander Sohmer , Alexander Epple , Jurgen Grunwald , Jorg Schultz , Christa Muller
发明人: Johannes Wangler , Karl-Heinz Schuster , Alexander Sohmer , Alexander Epple , Jurgen Grunwald , Jorg Schultz , Christa Muller
IPC分类号: G02B21/02
CPC分类号: G03F7/70891 , G02B13/143 , G02B13/18 , G03F7/70066 , G03F7/70075
摘要: A reticle-masking (REMA) objective for imaging an object plane onto an image plane has a condenser portion, an intermediate portion, and a field lens portion. The three portions together have no more than 10 lenses with a combined total of no more than five aspheric lens surfaces. Each of the three portions of the REMA objective has one or two aspheric lens surfaces.
摘要翻译: 用于将物平面成像到图像平面上的掩模版掩模(REMA)物镜具有聚光部分,中间部分和场透镜部分。 三个部分一起不超过10个透镜,总共不超过五个非球面透镜表面。 REMA物镜的三个部分中的每一个具有一个或两个非球面透镜表面。
-
公开(公告)号:US20100048501A1
公开(公告)日:2010-02-25
申请号:US12293983
申请日:2007-03-21
申请人: Jurgen Schrader , Christa Muller , All El-Tayeb , Jamshed Iqbal
发明人: Jurgen Schrader , Christa Muller , All El-Tayeb , Jamshed Iqbal
IPC分类号: A61K31/7076 , C07H19/20 , G01N33/53 , A61P19/00 , A61P25/00
CPC分类号: C07H19/20
摘要: A phosphorylated A2A receptor agonist providing agonist properties on the A2A receptor after dephosphorylation the phosphorylated A2A receptor agonist comprises a ribosyl moiety and a purine moiety and being phosphorylated at the 5′-position of the ribose moiety except adenosine monophosphate (AMP), adenosine diphosphate (ADP) or adenosine triphosphate (ATP), a medicament containing the compound of the invention including ADP and the use of the compound of the invention including ATP and ADP for several medical indications e. g. inflammatory events. In particular, compounds of formula (I) are also disclosed.
摘要翻译: 在磷酸化A2A受体激动剂脱磷酸化后,在A2A受体上提供激动剂性质的磷酸化A2A受体激动剂包含核糖基部分和嘌呤部分,并且在核糖部分的5'-位被磷酸化,除了腺苷一磷酸(AMP),二磷酸腺苷 ADP)或三磷酸腺苷(ATP),含有包含ADP的本发明化合物的药物,以及包括ATP和ADP在内的多种医学适应症的本发明化合物的用途。 G。 炎性事件。 特别地,还公开了式(I)的化合物。
-
4.
公开(公告)号:US5087570A
公开(公告)日:1992-02-11
申请号:US192378
申请日:1988-05-10
CPC分类号: A61K35/28 , C07K14/52 , G01N33/5005 , Y10S436/808
摘要: Highly concentrated hematopoietic stem cell compositions are provided which are substantially free of differentiated or dedicated hematopoietic cells. The cells are obtained by subtraction of cells having particular markers and selection of cells having particular markers. The resulting composition may be used to provide for individual or groups of hematopoietic lineages, to reconstitute stem cells of the host, and to identify an assay for a wide variety of hematopoietic growth factors.
-
-
-