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公开(公告)号：US20090319081A1
公开(公告)日：2009-12-24
申请号：US12443582
申请日：2007-09-28
IPC分类号： G05B19/4061 , G06G7/66 , G06F19/00
CPC分类号： G05B19/4061 , G05B2219/39082 , G05B2219/39098 , G05B2219/49138
摘要： A method for simulating a movement zone of a robot having at least one data processing installation, simulating at least one movement path of the robot, comprises providing a number of selectable points on the at least one movement path of the robot, calculating a braking path for each of the selectable points, calculating a virtual movement zone based on the braking paths and a maximum position reachable by the robot for the respective at least one movement path, and carrying out the simulation of functions of the robot off-line using a software module.
摘要翻译： 一种用于模拟具有至少一个数据处理装置的机器人的移动区域的方法，模拟所述机器人的至少一个移动路径，包括在所述机器人的所述至少一个移动路径上提供多个可选点，计算制动路径 对于每个可选点，基于制动路径计算虚拟移动区域和针对相应的至少一个移动路径的机器人可达到的最大位置，并且使用软件对离线机器人的功能进行模拟 模块。
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2.发明授权Feedback-resistant homoserine transsuccinylases having a modified c-terminus 失效具有修饰的c-末端的反馈抗高丝氨酸跨琥珀酰基酶公开(公告)号：US07195897B2
公开(公告)日：2007-03-27
申请号：US10530844
申请日：2003-10-16
CPC分类号： C12N9/1029 , C12P13/12 , C12P19/40
摘要： The invention relates to a homoserine transsuccinylase, which exhibits reduced sensitivity towards L-methionine or SAM in comparison with a homoserine transsuccinylase wild-type enzyme, whereby the latter comprises an amino acid sequence containing a TyrGlnXaaThrPro sub-sequence, the Thr of said sub-sequence lying between positions 285 and 310 of the amino acid sequence and position 1 being filled by the starter methionine. The inventive homoserine transsuccinylase is characterized in that in comparison with the wild-type enzyme at least 2 amino acids are modified, said modification taking place in the Thr of the sub-sequence or in the C-terminal.
摘要翻译： 本发明涉及与高丝氨酸反式琥珀酰基酶野生型酶相比对L-甲硫氨酸或SAM具有降低的敏感性的高丝氨酸跨琥珀酰基酶，其中后者包含含有TyrGlnXaaThrPro子序列的氨基酸序列， 位于氨基酸序列的位置285和310之间的序列，位置1由起始蛋氨酸填充。 本发明的高丝氨酸跨琥珀酰基酶的特征在于，与野生型酶相比，至少2个氨基酸被修饰，所述修饰发生在子序列的Thr或C末端。
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公开(公告)号：US07371551B1
公开(公告)日：2008-05-13
申请号：US10530843
申请日：2003-10-02
CPC分类号： C12N9/1029 , C12P13/12 , C12P19/40
摘要： The invention concerns a homoserine transsuccinylase having at least one mutation compared to a wild-type homoserine transsuccinylase and reduced sensitivity towards a L-methionine or SAM, compared to the wild-type enzyme. The latter comprises an amino acid sequence including a partial AspGlyXaaXaaXaaThrGlyAlaPro sequence between position 90 and position 115 and a partial TyrGlnXaaThrPro sequence between position 285 and position 310, position 1 of the amino acid sequence corresponding to the initial methionine. The invention is characterized in that the mutation is a substitution of the aspartate in the partial AspGlyXaaXaaXaaThrGlyAlaPro sequence, or a substitution of the tyrosine in the partial TyrGlnXaaThrPro sequence.
摘要翻译： 与野生型酶相比，本发明涉及与野生型高丝氨酸跨苏糖酰基酶相比具有至少一个突变的高丝氨酸跨琥珀酰酶和对L-甲硫氨酸或SAM的敏感性降低。 后者包括氨基酸序列，其包含位于第90位和第115位之间的部分AspGlyXaaXaaXaaThrGlyAlaPro序列和位于第285位和310位之间的部分TyrGlnXaaThrPro序列，对应于初始甲硫氨酸的氨基酸序列的位置1。 本发明的特征在于突变是部分AspGlyXaaXaaXaaThrGlyAlaPro序列中天冬氨酸的取代，或部分TyrGlnXaaThrPro序列中的酪氨酸取代。
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4.发明授权Microorganisms and processes for the fermentative preparation of L-cysteine, L-cystine, N-acetylserine or thiazolidine derivatives 失效L-半胱氨酸，L-胱氨酸，N-乙酰丝氨酸或噻唑烷衍生物的发酵制剂的微生物和方法
公开(公告)号：US5972663A
公开(公告)日：1999-10-26
申请号：US97759
申请日：1998-06-16
CPC分类号： C12P13/12 , C07K14/245
摘要： Microorganisms and processes for the fermentative preparation of L-cysteine, L-cystine, N-acetylserine or thiazolidine derivatives. The microorganism strain which is suitable for the fermentative preparation of L-cysteine, L-cystine, N-acetylserine and/or thiazolidine derivatives, overexpresses at least one gene which encodes a protein which is directly suitable for secreting antibiotics, or other substances which are toxic for the microorganism, out of the cell.
摘要翻译： L-半胱氨酸，L-胱氨酸，N-乙酰丝氨酸或噻唑烷衍生物的发酵制剂的微生物和方法。 适用于L-半胱氨酸，L-胱氨酸，N-乙酰丝氨酸和/或噻唑烷衍生物的发酵制剂的微生物菌株过表达至少一种编码直接适于分泌抗生素的蛋白质的基因或其它 对微生物有毒，离开细胞。
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公开(公告)号：US08326590B2
公开(公告)日：2012-12-04
申请号：US12443582
申请日：2007-09-28
IPC分类号： G06G7/48
CPC分类号： G05B19/4061 , G05B2219/39082 , G05B2219/39098 , G05B2219/49138
摘要： A method for simulating a movement zone of a robot having at least one data processing installation, simulating at least one movement path of the robot, comprises providing a number of selectable points on the at least one movement path of the robot, calculating a braking path for each of the selectable points, calculating a virtual movement zone based on the braking paths and a maximum position reachable by the robot for the respective at least one movement path, and carrying out the simulation of functions of the robot off-line using a software module.
摘要翻译： 一种用于模拟具有至少一个数据处理装置的机器人的移动区域的方法，模拟所述机器人的至少一个移动路径，包括在所述机器人的所述至少一个移动路径上提供多个可选点，计算制动路径 对于每个可选点，基于制动路径计算虚拟移动区域和针对相应的至少一个移动路径的机器人可达到的最大位置，并且使用软件对离线机器人的功能进行模拟 模块。
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公开(公告)号：US20090298135A1
公开(公告)日：2009-12-03
申请号：US10768528
申请日：2004-01-30
CPC分类号： C12P13/12
摘要： A microorganism strain suitable for fermentative production of L-methionine and preparable from a starting strain, which comprises increased activity of a yjeH gene product or of a gene product of a yjeH homolog, compared to the starting strain.
摘要翻译： 适于发酵生产L-甲硫氨酸并且可由起始菌株制备的微生物菌株，其与起始菌株相比包含增加yjeH基因产物或yjeH同源物的基因产物的活性。
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7.发明申请Feedback-resistant homoserine transsuccinylases having a modified c terminus 失效具有修饰的c末端的反馈抗高丝氨酸转氨基酰基酶公开(公告)号：US20060160173A1
公开(公告)日：2006-07-20
申请号：US10530844
申请日：2003-10-16
CPC分类号： C12N9/1029 , C12P13/12 , C12P19/40
摘要： The invention relates to a homoserine transsuccinylase, which exhibits reduced sensitivity towards L-methionine or SAM in comparison with a homoserine transsuccinylase wild-type enzyme, whereby the latter comprises an amino acid sequence containing a TyrGlnXaaThrPro sub-sequence, the Thr of said sub-sequence lying between positions 285 and 310 of the amino acid sequence and position 1 being filled by the starter methionine. The inventive homoserine transsuccinylase is characterized in that in comparison with the wild-type enzyme at least 2 amino acids are modified, said modification taking place in the Thr of the sub-sequence or in the C-terminal.
摘要翻译： 本发明涉及与高丝氨酸反式琥珀酰基酶野生型酶相比对L-甲硫氨酸或SAM具有降低的敏感性的高丝氨酸跨琥珀酰基酶，其中后者包含含有TyrGlnXaaThrPro子序列的氨基酸序列， 位于氨基酸序列的位置285和310之间的序列，位置1由起始蛋氨酸填充。 本发明的高丝氨酸跨琥珀酰基酶的特征在于，与野生型酶相比，至少2个氨基酸被修饰，所述修饰发生在子序列的Thr或C末端。
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