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1.发明授权公开(公告)号：US08877269B2
公开(公告)日：2014-11-04
申请号：US13596316
申请日：2012-08-28
Applicant: Yu-Hui Liu , Chien-Ti Chang , Ming-Yu Hung , Shiao-Cheng Chuang , Su-Er Liou , Fu-Ning Chien , Hsiang-Ling Lai , Yi-Hong Chen , Chu-Chin Chen
Inventor： Yu-Hui Liu , Chien-Ti Chang , Ming-Yu Hung , Shiao-Cheng Chuang , Su-Er Liou , Fu-Ning Chien , Hsiang-Ling Lai , Yi-Hong Chen , Chu-Chin Chen
CPC classification number: A23L1/20 , A23L5/00 , A23L11/00 , A23L11/03 , A23L11/30 , A23L29/30 , A23L33/125 , A23L33/135 , A23L33/21
Abstract: Provided is a soybean oligosaccharide product containing acidic soluble saccharides of soybean and probiotics, which at least include fructose, glucose, sucrose, raffinose, and stachyose, with a percentage of the combined weight of raffinose and stachyose being at least 46%, a weight percentage of fructose being not greater than 8.5%, and a weight percentage of glucose being not greater than 1.0%, based on the total weight of fructose, glucose, sucrose, raffinose, and stachyose. The soybean oligosaccharide product is prepared by extracting a soybean raw material with water under a pH of 3-6 and at a temperature of 50-70° C. to obtain an extract containing acidic soluble saccharides of soybean, and inoculating and fermenting the extract with probiotics that are able to decompose monosaccharides and disaccharides, but substantially not able to decompose trisaccharides or tetrasaccharides.
Abstract translation: 本发明提供含有大豆和益生菌的酸性可溶性糖的大豆寡糖产物，其至少包括果糖，葡萄糖，蔗糖，棉子糖和水苏糖，棉子糖和水苏糖的组合重量的百分比至少为46％，重量百分比 的果糖不大于8.5％，葡萄糖的重量百分比不大于1.0％，基于果糖，葡萄糖，蔗糖，棉子糖和水苏糖的总重量。 大豆低聚糖产物通过在pH 3-6，温度50-70℃下用水提取大豆原料，得到含有大豆酸性可溶性糖的提取物，并将该提取物与 能够分解单糖和二糖但基本上不能分解三糖或四糖的益生菌。
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2.发明授权公开(公告)号：US08673862B1
公开(公告)日：2014-03-18
申请号：US13604969
申请日：2012-09-06
Applicant: Yi-Hong Chen , Hsiang-Ling Lai , Shiao-Cheng Chuang , Chien-Ti Chang , Ming-Yu Hung , Yu-Hui Liu , Su-Er Liou , Fu-Ning Chien , Chu-Chin Chen
Inventor： Yi-Hong Chen , Hsiang-Ling Lai , Shiao-Cheng Chuang , Chien-Ti Chang , Ming-Yu Hung , Yu-Hui Liu , Su-Er Liou , Fu-Ning Chien , Chu-Chin Chen
CPC classification number: A61K38/08 , A61K38/556 , C07K7/06 , C07K17/06
Abstract: Peptides useful as angiotensin converting enzyme inhibitors are provided. Also provided are compositions comprising one or more of the peptides and methods for preventing, treating and/or diminishing one or more syndromes associated with angiotensin converting enzyme by using the peptides.
Abstract translation: 提供了可用作血管紧张素转化酶抑制剂的肽。 还提供了包含一种或多种肽的组合物和通过使用肽来预防，治疗和/或减少与血管紧张素转换酶相关的一种或多种综合征的方法。
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3.发明申请公开(公告)号：US20090239809A1
公开(公告)日：2009-09-24
申请号：US12332677
申请日：2008-12-11
Applicant: Yi-Hong Chen , Yu-Hui Liu , Chu-Chin Chen , Shiao-Cheng Chuang , Hsiang-Ling Lai , Chien-Ti Chang , Ming-Yu Hung , Su-Er Liou , Fu-Ning Chien
Inventor： Yi-Hong Chen , Yu-Hui Liu , Chu-Chin Chen , Shiao-Cheng Chuang , Hsiang-Ling Lai , Chien-Ti Chang , Ming-Yu Hung , Su-Er Liou , Fu-Ning Chien
CPC classification number: A61K36/48 , C07K5/06026 , C07K5/06043 , C07K5/06052 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06104 , C07K5/06113 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/101
Abstract: A process for producing a peptide product having cholecystokinin secretion promoting effect, said process comprising hydrolyzing soybean residues with one or more proteases so that the peptide product having cholecystokinin secretion promoting effect is obtained. Also disclosed is the composition containing the peptide product and the use thereof.
Abstract translation: 一种生产具有缩胆囊素分泌促进作用的肽产物的方法，所述方法包括用一种或多种蛋白酶水解大豆残留物，从而获得具有促胆缩胆囊素分泌作用的肽产物。 还公开了含有肽产物的组合物及其用途。
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4.发明申请公开(公告)号：US20140066361A1
公开(公告)日：2014-03-06
申请号：US13604969
申请日：2012-09-06
Applicant: YI-HONG CHEN , HSIANG-LING LAI , SHIAO-CHENG CHUANG , CHIEN-TI CHANG , MING-YU HUNG , YU-HUI LIU , SU-ER LIOU , FU-NING CHIEN , CHU-CHIN CHEN
Inventor： YI-HONG CHEN , HSIANG-LING LAI , SHIAO-CHENG CHUANG , CHIEN-TI CHANG , MING-YU HUNG , YU-HUI LIU , SU-ER LIOU , FU-NING CHIEN , CHU-CHIN CHEN
IPC: C07K5/083 , C07K5/113 , C07K5/087 , C07K7/06 , C07K5/093 , C07K5/062 , C07K5/068 , C07K5/103 , C07K5/078 , A61K38/05 , A61K38/06 , A61K38/07 , A61K38/08 , A61P9/12 , A61P9/10 , A61P7/02 , A61P9/04 , A61P9/00 , A61P3/00 , C07K5/065
CPC classification number: A61K38/08 , A61K38/556 , C07K7/06 , C07K17/06
Abstract: Peptides useful as angiotensin converting enzyme inhibitors are provided. Also provided are compositions comprising one or more of the peptides and methods for preventing, treating and/or diminishing one or more syndromes associated with angiotensin converting enzyme by using the peptides.
Abstract translation: 提供了可用作血管紧张素转化酶抑制剂的肽。 还提供了包含一种或多种肽的组合物和通过使用肽来预防，治疗和/或减少与血管紧张素转换酶相关的一种或多种综合征的方法。
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5.发明授权Process for preparing peptide products for promoting cholecystokinin secretion and use of the peptide products 有权制备肽产物以促进胆囊收缩素分泌和使用肽产物的方法公开(公告)号：US08063017B2
公开(公告)日：2011-11-22
申请号：US12332677
申请日：2008-12-11
Applicant: Yi-Hong Chen , Yu-Hui Liu , Chu-Chin Chen , Shiao-Cheng Chuang , Hsiang-Ling Lai , Chien-Ti Chang , Ming-Yu Hung , Su-Er Liou , Fu-Ning Chien
Inventor： Yi-Hong Chen , Yu-Hui Liu , Chu-Chin Chen , Shiao-Cheng Chuang , Hsiang-Ling Lai , Chien-Ti Chang , Ming-Yu Hung , Su-Er Liou , Fu-Ning Chien
CPC classification number: A61K36/48 , C07K5/06026 , C07K5/06043 , C07K5/06052 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06104 , C07K5/06113 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/101
Abstract: A process for producing a peptide product having cholecystokinin secretion promoting effect, said process comprising hydrolyzing soybean residues with one or more proteases so that the peptide product having cholecystokinin secretion promoting effect is obtained. Also disclosed is the composition containing the peptide product and the use thereof.
Abstract translation: 一种生产具有缩胆囊素分泌促进作用的肽产物的方法，所述方法包括用一种或多种蛋白酶水解大豆残留物，从而获得具有促胆缩胆囊素分泌作用的肽产物。 还公开了含有肽产物的组合物及其用途。
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Patent Agency Ranking
6.发明授权Peptides used as angiotensin converting enzyme inhibitor and preparation process thereof 有权用作血管紧张素转换酶抑制剂的肽及其制备方法公开(公告)号：US07335722B2
公开(公告)日：2008-02-26
申请号：US10818999
申请日：2004-04-05
Applicant: Yi-Hong Chen , Yung-Hsiang Yang , Yu-Hui Liu , Chien-Ti Chang , Hsiao-Hui Feng , Chu-Chin Chen
Inventor： Yi-Hong Chen , Yung-Hsiang Yang , Yu-Hui Liu , Chien-Ti Chang , Hsiao-Hui Feng , Chu-Chin Chen
Abstract: The invention discloses five peptides which can be used as angiotensin converting enzyme inhibitor. The subject invention also discloses a process for the preparation of the products having angiotensin converting enzyme inhibitory activity, which comprises the following steps: (a) adding protein hydrolase to the solution of chicken residues for reaction; (b) separating the chicken residues and liquid after the reaction of step (a) and collecting the separated liquid; and (c) drying the liquid obtained from step (b) to obtain the products.
Abstract translation: 本发明公开了可用作血管紧张素转换酶抑制剂的五种肽。 本发明还公开了一种制备具有血管紧张素转换酶抑制活性的产品的方法，其包括以下步骤：（a）向鸡残留物溶液中加入蛋白质水解酶进行反应; （b）在步骤（a）反应后分离鸡残渣和液体并收集分离的液体; 和（c）将从步骤（b）获得的液体干燥以获得产品。
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7.发明申请公开(公告)号：US20130323360A1
公开(公告)日：2013-12-05
申请号：US13596316
申请日：2012-08-28
Applicant: YU-HUI LIU , CHIEN-TI CHANG , MING-YU HUNG , SHIAO-CHENG CHUANG , SU-ER LIOU , FU-NING CHIEN , HSIANG-LING LAI , YI-HONG CHEN , CHU-CHIN CHEN
Inventor： YU-HUI LIU , CHIEN-TI CHANG , MING-YU HUNG , SHIAO-CHENG CHUANG , SU-ER LIOU , FU-NING CHIEN , HSIANG-LING LAI , YI-HONG CHEN , CHU-CHIN CHEN
CPC classification number: A23L1/20 , A23L5/00 , A23L11/00 , A23L11/03 , A23L11/30 , A23L29/30 , A23L33/125 , A23L33/135 , A23L33/21
Abstract: Provided is a soybean oligosaccharide product containing acidic soluble saccharides of soybean and probiotics, which at least include fructose, glucose, sucrose, raffinose, and stachyose, with a percentage of the combined weight of raffinose and stachyose being at least 46%, a weight percentage of fructose being not greater than 8.5%, and a weight percentage of glucose being not greater than 1.0%, based on the total weight of fructose, glucose, sucrose, raffinose, and stachyose. The soybean oligosaccharide product is prepared by extracting a soybean raw material with water under a pH of 3-6 and at a temperature of 50-70° C. to obtain an extract containing acidic soluble saccharides of soybean, and inoculating and fermenting the extract with probiotics that are able to decompose monosaccharides and disaccharides, but substantially not able to decompose trisaccharides or tetrasaccharides.
Abstract translation: 本发明提供含有大豆和益生菌的酸性可溶性糖的大豆寡糖产物，其至少包括果糖，葡萄糖，蔗糖，棉子糖和水苏糖，棉子糖和水苏糖的组合重量的百分比至少为46％，重量百分比 的果糖不大于8.5％，葡萄糖的重量百分比不大于1.0％，基于果糖，葡萄糖，蔗糖，棉子糖和水苏糖的总重量。 大豆低聚糖产物通过在pH 3-6，温度50-70℃下用水提取大豆原料，得到含有大豆酸性可溶性糖的提取物，并将该提取物与 能够分解单糖和二糖但基本上不能分解三糖或四糖的益生菌。
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8.发明申请公开(公告)号：US20120270813A1
公开(公告)日：2012-10-25
申请号：US13253450
申请日：2011-10-05
Applicant: Yi-Hong Chen , Yu-Hui Liu , Chu-Chin Chen , Shiao-Cheng Chuang , Hsiang-Ling Lai , Chien-Ti Chang , Ming-Yu Hung , Su-Er Liou , Fu-Ning Chien
Inventor： Yi-Hong Chen , Yu-Hui Liu , Chu-Chin Chen , Shiao-Cheng Chuang , Hsiang-Ling Lai , Chien-Ti Chang , Ming-Yu Hung , Su-Er Liou , Fu-Ning Chien
IPC: C07K2/00 , C07K5/103 , C07K5/087 , C07K5/09 , C07K5/062 , A61K38/07 , C07K5/065 , A61K38/02 , C12P21/06 , A61K38/05 , A61K38/06 , C07K5/083 , C07K5/072
CPC classification number: A61K36/48 , C07K5/06026 , C07K5/06043 , C07K5/06052 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06104 , C07K5/06113 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/101
Abstract: A process for producing a peptide product having cholecystokinin secretion promoting effect, said process comprising hydrolyzing soybean residues with one or more proteases so that the peptide product having cholecystokinin secretion promoting effect is obtained. Also disclosed is the composition containing the peptide product and the use thereof.
Abstract translation: 一种生产具有缩胆囊素分泌促进作用的肽产物的方法，所述方法包括用一种或多种蛋白酶水解大豆残留物，从而获得具有促胆缩胆囊素分泌作用的肽产物。 还公开了含有肽产物的组合物及其用途。
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9.发明授权Peptides used as angiotensin converting enzyme inhibitor and preparation process thereof 有权用作血管紧张素转换酶抑制剂的肽及其制备方法公开(公告)号：US06767990B1
公开(公告)日：2004-07-27
申请号：US09572531
申请日：2000-05-17
Applicant: Yi-Hong Chen , Yung-Hsiang Yang , Yu-Hui Liu , Chien-Ti Chang , Hsiao-Hui Feng , Chu-Chin Chen
Inventor： Yi-Hong Chen , Yung-Hsiang Yang , Yu-Hui Liu , Chien-Ti Chang , Hsiao-Hui Feng , Chu-Chin Chen
IPC: A61K3800
Abstract: The invention discloses five novel peptides which can be used as angiotensin converting enzyme inhibitor. The subject invention also discloses a process for the preparation of the products having angiotensin converting enzyme inhibitory activity, which comprises the following steps: (a) adding protein hydrolase to the solution of chicken residues for reaction; (b) separating the chicken residues and liquid after the reaction of step (a) and collecting the separated liquid; and (c) drying the liquid obtained from step (b) to obtain the products.
Abstract translation: 本发明公开了可用作血管紧张素转换酶抑制剂的五种新型肽。 本发明还公开了一种制备具有血管紧张素转换酶抑制活性的产品的方法，其包括以下步骤：（a）向鸡残留物溶液中加入蛋白质水解酶进行反应;（b）将鸡残留物和液体 在步骤（a）的反应之后并收集分离的液体; 和（c）将从步骤（b）获得的液体干燥以获得产品。
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10.发明授权Process for preparing peptide products for promoting cholecystokinin secretion and use of the peptide products 有权制备肽产物以促进胆囊收缩素分泌和使用肽产物的方法公开(公告)号：US08501685B2
公开(公告)日：2013-08-06
申请号：US13253450
申请日：2011-10-05
Applicant: Yi-Hong Chen , Yu-Hui Liu , Chu-Chin Chen , Shiao-Cheng Chuang , Hsiang-Ling Lai , Chien-Ti Chang , Ming-Yu Hung , Su-Er Liou , Fu-Ning Chien
Inventor： Yi-Hong Chen , Yu-Hui Liu , Chu-Chin Chen , Shiao-Cheng Chuang , Hsiang-Ling Lai , Chien-Ti Chang , Ming-Yu Hung , Su-Er Liou , Fu-Ning Chien
CPC classification number: A61K36/48 , C07K5/06026 , C07K5/06043 , C07K5/06052 , C07K5/0606 , C07K5/06069 , C07K5/06078 , C07K5/06104 , C07K5/06113 , C07K5/0806 , C07K5/0808 , C07K5/081 , C07K5/0812 , C07K5/0815 , C07K5/101
Abstract: A process for producing a peptide product having cholecystokinin secretion promoting effect, said process comprising hydrolyzing soybean residues with one or more proteases so that the peptide product having cholecystokinin secretion promoting effect is obtained. Also disclosed is the composition containing the peptide product and the use thereof.
Abstract translation: 一种生产具有缩胆囊素分泌促进作用的肽产物的方法，所述方法包括用一种或多种蛋白酶水解大豆残留物，从而获得具有促胆缩胆囊素分泌作用的肽产物。 还公开了含有肽产物的组合物及其用途。
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