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1.发明申请Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment 审中-公开烟酸受体激动剂，包含这些化合物的组合物和治疗方法公开(公告)号：US20090170891A1
公开(公告)日：2009-07-02
申请号：US12226050
申请日：2007-04-06
申请人： Steven L. Colletti , James R. Tata , Weichun Chen , Richard T. Beresis , Fa-Xiang Ding , Darby Rye Schmidt , Hong Shen , Subharekha Raghavan
发明人： Steven L. Colletti , James R. Tata , Weichun Chen , Richard T. Beresis , Fa-Xiang Ding , Darby Rye Schmidt , Hong Shen , Subharekha Raghavan
IPC分类号： A61K31/4375 , C07D333/36 , A61K31/381 , C07D413/04 , A61K31/444 , C07D333/38 , A61P3/10
CPC分类号： C07D333/38 , C07D277/56 , C07D333/40 , C07D413/14
摘要： The present invention encompasses compounds of Formula I: as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.
摘要翻译： 本发明包括可用于治疗动脉粥样硬化，血脂异常等的式I化合物及其药学上可接受的盐和水合物。 还包括药物组合物和使用方法。
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2.发明申请Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment 审中-公开烟酸受体激动剂，包含这些化合物的组合物和治疗方法公开(公告)号：US20090042926A1
公开(公告)日：2009-02-12
申请号：US12086938
申请日：2006-12-20
申请人： Jason Imbriglio , Steven L. Colletti , James R. Tata , Richard T. Beresis , Daria Marley , Subharekha Raghavan , Darby Rye Schmidt , Ashley Rouse Lins , Abigail L. Smenton , Weichun Chen , Hong Shen , Fa-Xiang Ding , Rena Bodner
发明人： Jason Imbriglio , Steven L. Colletti , James R. Tata , Richard T. Beresis , Daria Marley , Subharekha Raghavan , Darby Rye Schmidt , Ashley Rouse Lins , Abigail L. Smenton , Weichun Chen , Hong Shen , Fa-Xiang Ding , Rena Bodner
IPC分类号： A61K31/4439 , C07C229/34 , C07D277/22 , C07D271/06 , C07D413/04 , A61K31/437 , A61P9/10 , A61P3/10 , C07D471/04 , A61K31/196 , A61K31/426 , A61K31/4245
CPC分类号： C07D277/28 , C07C237/20 , C07D231/12 , C07D263/32 , C07D271/06 , C07D401/04 , C07D413/04 , C07D413/14 , C07D471/04
摘要： The present invention encompasses compounds of Formula (I): as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.
摘要翻译： 本发明包括可用于治疗动脉粥样硬化，血脂异常等的式（I）化合物及其药学上可接受的盐和水合物。 还包括药物组合物和使用方法。
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3.发明授权Niacin receptor agonists, compositions containing such compounds and methods of treatment 有权烟酸受体激动剂，含有这些化合物的组合物和治疗方法公开(公告)号：US08168649B2
公开(公告)日：2012-05-01
申请号：US11922629
申请日：2006-06-26
申请人： Subharekha Raghavan , Steven L. Colletti , Fa-Xiang Ding , Hong Shen , James R. Tata , Ashley Rouse Lins , Abigail Lee Smenton , Weichun Chen , Darby Rye Schmidt , George Scott Tria
发明人： Subharekha Raghavan , Steven L. Colletti , Fa-Xiang Ding , Hong Shen , James R. Tata , Ashley Rouse Lins , Abigail Lee Smenton , Weichun Chen , Darby Rye Schmidt , George Scott Tria
IPC分类号： A61K31/44 , A01N43/40 , A61K31/19 , A61K31/165
CPC分类号： C07D261/20 , C07C233/52 , C07C233/55 , C07C235/36 , C07C237/20 , C07C2601/10 , C07C2601/16 , C07D231/12 , C07D249/06 , C07D249/08 , C07D257/04 , C07D271/06 , C07D277/30 , C07D307/79 , C07D309/14 , C07D309/28 , C07D401/04 , C07D413/04 , C07D417/04 , C07D513/04
摘要： The present invention encompasses compounds of Formula (I): as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.
摘要翻译： 本发明包括可用于治疗动脉粥样硬化，血脂异常等的式（I）化合物及其药学上可接受的盐和水合物。 还包括药物组合物和使用方法。
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4.发明申请Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment 有权烟酸受体激动剂，包含这些化合物的组合物和治疗方法公开(公告)号：US20100144778A1
公开(公告)日：2010-06-10
申请号：US11922629
申请日：2006-06-26
申请人： Subharekha Raghavan , Steven L. Colletti , Fa-Xiang Ding , Hong Shen , James R. Tata , Ashley Rouse Lins , Abigail Lee Smenton , Weichun Chen , Darby Rye Schmidt , George Scott Tria
发明人： Subharekha Raghavan , Steven L. Colletti , Fa-Xiang Ding , Hong Shen , James R. Tata , Ashley Rouse Lins , Abigail Lee Smenton , Weichun Chen , Darby Rye Schmidt , George Scott Tria
IPC分类号： A61K31/437 , C07C233/02 , C07C229/38 , C07D413/04 , C07D513/04 , C07D471/14 , A61K31/165 , A61K31/192 , A61K31/4439 , A61K31/4245 , A61P9/10
CPC分类号： C07D261/20 , C07C233/52 , C07C233/55 , C07C235/36 , C07C237/20 , C07C2601/10 , C07C2601/16 , C07D231/12 , C07D249/06 , C07D249/08 , C07D257/04 , C07D271/06 , C07D277/30 , C07D307/79 , C07D309/14 , C07D309/28 , C07D401/04 , C07D413/04 , C07D417/04 , C07D513/04
摘要： The present invention encompasses compounds of Formula (I): as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.
摘要翻译： 本发明包括可用于治疗动脉粥样硬化，血脂异常等的式（I）化合物及其药学上可接受的盐和水合物。 还包括药物组合物和使用方法。
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5.发明申请Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment 审中-公开烟酸受体激动剂，包含这些化合物的组合物和治疗方法公开(公告)号：US20120178750A1
公开(公告)日：2012-07-12
申请号：US13423618
申请日：2012-03-19
申请人： Subharekha Raghavan , Steven L. Colletti , Fa-Xiang Ding , Hong Shen , James R. Tata , Ashley Rouse Lins , Abigail Lee Smenton , Weichun Chen , Darby Rye Schmidt , George Scott Tria
发明人： Subharekha Raghavan , Steven L. Colletti , Fa-Xiang Ding , Hong Shen , James R. Tata , Ashley Rouse Lins , Abigail Lee Smenton , Weichun Chen , Darby Rye Schmidt , George Scott Tria
IPC分类号： A61K31/4439 , A61K31/423 , A61K31/429 , A61K31/41 , A61K31/426 , A61K31/427 , A61K31/403 , A61K31/4375 , A61K31/437 , A61K31/538 , A61K31/4196 , A61P9/10 , A61P3/06 , A61P3/10 , A61P3/00 , A61K31/196
CPC分类号： C07D261/20 , C07C233/52 , C07C233/55 , C07C235/36 , C07C237/20 , C07C2601/10 , C07C2601/16 , C07D231/12 , C07D249/06 , C07D249/08 , C07D257/04 , C07D271/06 , C07D277/30 , C07D307/79 , C07D309/14 , C07D309/28 , C07D401/04 , C07D413/04 , C07D417/04 , C07D513/04
摘要： The present invention encompasses compounds of Formula I: as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.
摘要翻译： 本发明包括可用于治疗动脉粥样硬化，血脂异常等的式I化合物及其药学上可接受的盐和水合物。 还包括药物组合物和使用方法。
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6.发明申请公开(公告)号：US20090062269A1
公开(公告)日：2009-03-05
申请号：US12223492
申请日：2007-02-02
IPC分类号： A61K31/195 , C07D277/30 , C07C229/46 , C07D211/78 , C07D213/61 , C07D213/56 , A61K31/444 , A61K31/4418 , A61K31/381 , A61K31/538 , A61K31/4375 , A61K31/404 , A61K31/437 , A61P3/10 , A61K31/426 , A61K31/4439 , C07D413/14 , C07D403/04 , C07D401/04 , C07D333/24 , A61P3/00
CPC分类号： C07C235/34 , C07C233/52 , C07C2601/16 , C07D211/78 , C07D213/55 , C07D213/61 , C07D277/30 , C07D333/24 , C07D401/04 , C07D413/04
摘要： The present invention encompasses compounds of Formula I: as well as pharmaceutically acceptable salts and hydrates thereof, that are useful for treating atherosclerosis, dyslipidemias and the like. Pharmaceutical compositions and methods of use are also included.
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