公开(公告)号：US08966012B2

公开(公告)日：2015-02-24

申请号：US13598564

申请日：2012-08-29

Applicant: David Drysdale ,  Michael Bell

Inventor： David Drysdale ,  Michael Bell

IPC: G06F15/16 ,  H04L12/911 ,  H04W4/00 ,  G06F12/00

CPC classification number: H04L67/1002 ,  H04L47/70 ,  H04W4/50 ,  H04W4/60

Abstract: Processing data in a communications system comprising a plurality of servers is provided. First data received from a communications device is directed to a given server in the plurality of servers. A server identifier identifying the given server is transmitted to the communications device. Subsequent data is received from the communications device. The subsequent data comprises the server identifier and a further parameter. The given server is selected on the basis of at least the server identifier and some of the subsequent data received from the communications device is directed to the given server. In the event of a need to redirect subsequent data to a server other than the given server, a different server is selected on the basis of at least the further parameter and further of the subsequent data received from the communications device is directed to the selected different server.

Abstract translation: 提供了包括多个服务器的通信系统中的处理数据。 从通信设备接收的第一数据被引导到多个服务器中的给定服务器。 标识给定服务器的服务器标识符被传送到通信设备。 从通信设备接收后续数据。 后续数据包括服务器标识符和另外的参数。 至少基于服务器标识符选择给定的服务器，并且从通信设备接收到的一些后续数据被定向到给定的服务器。 在需要将后续数据重定向到除了给定服务器之外的服务器的情况下，基于至少另外的参数选择不同的服务器，并且进一步从通信设备接收的后续数据被定向到所选择的不同 服务器。

公开(公告)号：US20130227058A1

公开(公告)日：2013-08-29

申请号：US13598564

申请日：2012-08-29

Applicant: David Drysdale ,  Michael Bell

Inventor： David Drysdale ,  Michael Bell

IPC: H04L12/70

CPC classification number: H04L67/1002 ,  H04L47/70 ,  H04W4/50 ,  H04W4/60

Abstract: Processing data in a communications system comprising a plurality of servers is provided. First data received from a communications device is directed to a given server in the plurality of servers. A server identifier identifying the given server is transmitted to the communications device. Subsequent data is received from the communications device. The subsequent data comprises the server identifier and a further parameter. The given server is selected on the basis of at least the server identifier and some of the subsequent data received from the communications device is directed to the given server. In the event of a need to redirect subsequent data to a server other than the given server, a different server is selected on the basis of at least the further parameter and further of the subsequent data received from the communications device is directed to the selected different server.

Abstract translation: 提供了包括多个服务器的通信系统中的处理数据。 从通信设备接收的第一数据被引导到多个服务器中的给定服务器。 标识给定服务器的服务器标识符被传送到通信设备。 从通信设备接收后续数据。 后续数据包括服务器标识符和另外的参数。 至少基于服务器标识符选择给定的服务器，并且从通信设备接收到的一些后续数据被定向到给定的服务器。 在需要将后续数据重定向到除了给定服务器之外的服务器的情况下，基于至少另外的参数选择不同的服务器，并且进一步从通信设备接收的后续数据被定向到所选择的不同 服务器。

公开(公告)号：US20080269200A1

公开(公告)日：2008-10-30

申请号：US10597154

申请日：2005-01-13

Applicant: Ian Robert Baldwin ,  Paul Bamborough ,  John Andrew Christopher ,  Jeffrey K Kerns ,  Timothy Longstaff ,  David Drysdale Miller

Inventor： Ian Robert Baldwin ,  Paul Bamborough ,  John Andrew Christopher ,  Jeffrey K Kerns ,  Timothy Longstaff ,  David Drysdale Miller

IPC: A61K31/55 ,  C07D209/04 ,  C07D401/04 ,  C07D405/04 ,  C07D403/04 ,  A61P37/02 ,  A61K31/404 ,  A61K31/506 ,  A61K31/4439

CPC classification number: C07D413/04 ,  C07D209/08 ,  C07D401/04 ,  C07D401/06 ,  C07D403/04 ,  C07D405/04 ,  C07D409/04 ,  C07D409/14

Abstract: Indole carboxamide compounds of Formula (I): are provided as inhibitors of kinase activity, in particular IKK2 activity as well as compositions and medicaments containing them, for use in inflammatory and tissue repair disorders.

Abstract translation: 提供式（I）的吲哚羧酰胺化合物：作为激酶活性的抑制剂，特别是IKK2活性以及含有它们的组合物和药物，用于炎性和组织修复障碍。

公开(公告)号：US07598251B2

公开(公告)日：2009-10-06

申请号：US12262290

申请日：2008-10-31

Applicant: Michael John Alberti ,  David Harold Drewry ,  David Drysdale Miller ,  Paul Bamborough

Inventor： Michael John Alberti ,  David Harold Drewry ,  David Drysdale Miller ,  Paul Bamborough

IPC: A61K31/4965 ,  C07D401/00 ,  C07D403/00 ,  C07D405/00 ,  C07D409/00 ,  C07D411/00 ,  C07D413/00 ,  C07D417/00 ,  C07D419/00

CPC classification number: C07D471/04 ,  C07D403/04 ,  C07D409/14 ,  C07D473/00 ,  C07D487/04

Abstract: The present invention relates to aminopyrazine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such aminopyrazine derivatives are useful in the treatment of diseases associated with inappropriate tyrosine and/or serine/threonine kinase activity.

Abstract translation: 本发明涉及氨基吡嗪衍生物，含有它们的组合物和药物，以及制备和使用这些化合物，组合物和药物的方法。 这种氨基吡嗪衍生物可用于治疗与不适当的酪氨酸和/或丝氨酸/苏氨酸激酶活性相关的疾病。

公开(公告)号：US6013807A

公开(公告)日：2000-01-11

申请号：US168318

申请日：1998-10-08

Applicant: David Drysdale Miller ,  Sadie Vile ,  Patrick Vivian Richard Shannon ,  Laddawan Chunchatprasert ,  Alan Thomas Hudson

Inventor： David Drysdale Miller ,  Sadie Vile ,  Patrick Vivian Richard Shannon ,  Laddawan Chunchatprasert ,  Alan Thomas Hudson

IPC: A61K31/40 ,  A61P35/00 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  C07F7/08 ,  C07D487/00

CPC classification number: C07D487/04 ,  C07D495/04 ,  C07F7/0812

Abstract: The present invention relates to heterocyclic compounds which have been found to have anti-tumour activity. More specifically, the invention concerns pyrrolo[2,3-b]carbazoles and 1H-[1] benzothieno [2,3-f] indoles, methods for their preparation, pharmaceutical formulations containing them and their use as anti-tumour agents. The compounds have low toxicity against normal cell lines whilst exhibiting anti-tumour cell activity.

Abstract translation: 本发明涉及已被发现具有抗肿瘤活性的杂环化合物。 更具体地，本发明涉及吡咯并[2,3-b]咔唑和1H- [1]苯并噻吩并[2,3-f]吲哚，其制备方法，含有它们的药物制剂及其作为抗肿瘤剂的用途。 该化合物对正常细胞系具有低毒性，同时具有抗肿瘤细胞活性。

公开(公告)号：US20110059979A1

公开(公告)日：2011-03-10

申请号：US10568028

申请日：2004-08-12

Applicant: Craig Jamieson ,  David Drysdale Miller ,  Harshad Kantilal Rami ,  Mervyn Thompson

Inventor： Craig Jamieson ,  David Drysdale Miller ,  Harshad Kantilal Rami ,  Mervyn Thompson

IPC: A61K31/506 ,  A61K31/501 ,  A61K31/4709 ,  A61K31/4545 ,  A61K31/454 ,  C07D403/02 ,  C07D401/02

CPC classification number: C04B35/632 ,  C07C311/46 ,  C07C317/40 ,  C07C2601/14 ,  C07D215/38 ,  C07D277/64 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/14

Abstract: Certain compounds of formula (I), or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, P, P′, X, m and n are as defined in the specification, a process for preparing such compounds, a pharmaceutical composition comprising such compounds and the use of such compounds in medicine.

Abstract translation: 某些式（I）化合物或其药学上可接受的盐或溶剂合物，其中R 1，R 2，P，P'，X，m和n如说明书中所定义，制备该化合物的方法， 这些化合物和这些化合物在医药中的应用。

公开(公告)号：US07459454B2

公开(公告)日：2008-12-02

申请号：US10549972

申请日：2004-03-18

Applicant: Michael John Alberti ,  David Harold Drewry ,  David Drysdale Miller ,  Paul Bamborough

Inventor： Michael John Alberti ,  David Harold Drewry ,  David Drysdale Miller ,  Paul Bamborough

IPC: A01N43/58 ,  A01N43/60 ,  A61K31/50 ,  A61K31/495 ,  A61K31/4965 ,  C07D487/00 ,  C07D473/00 ,  C07D239/02 ,  C07D401/00 ,  C07D403/00 ,  C07D405/00 ,  C07D409/00 ,  C07D411/00 ,  C07D413/00 ,  C07D417/00 ,  C07D419/00

CPC classification number: C07D471/04 ,  C07D403/04 ,  C07D409/14 ,  C07D473/00 ,  C07D487/04

Abstract: The present invention relates to aminopyrazine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medcicaments. Such aminopyrazine derivatives are useful in the treatment of diseases associated with inappropriate tyrosine and/or serine/threonine kinase activity.

Abstract translation: 本发明涉及氨基吡嗪衍生物，含有它们的组合物和药物，以及这些化合物，组合物和药物的制备和用途的方法。 这种氨基吡嗪衍生物可用于治疗与不适当的酪氨酸和/或丝氨酸/苏氨酸激酶活性相关的疾病。

公开(公告)号：US20130101106A1

公开(公告)日：2013-04-25

申请号：US13570145

申请日：2012-08-08

Applicant: Chris Mairs ,  Liz Rice ,  Philip Pearl ,  Felix Palmer ,  David Drysdale ,  Shaun Crampton ,  Michael Bell

Inventor： Chris Mairs ,  Liz Rice ,  Philip Pearl ,  Felix Palmer ,  David Drysdale ,  Shaun Crampton ,  Michael Bell

IPC: H04M3/56

CPC classification number: H04M3/56 ,  H04L12/1818 ,  H04M3/564 ,  H04M7/0027

Abstract: A method of processing data in relation to a teleconference service in a telecommunications network is provided. The teleconference service is able to handle a multi-party teleconference for three or more teleconference participants. First, second and third teleconference participation identifiers are received from first, second and third teleconference participants respectively. The first, second and third teleconference participation identifiers are correlated to determine that the first, second and third teleconference participants are participants in a given multi-party teleconference. Data is transmitted for enabling the establishment of a data communications session which is established separately from the teleconference. The data communications session is for the communication of data between a first data communication device associated with the first teleconference participant, a second data communication device associated with the second teleconference participant and a third data communication device associated with the third teleconference participant.

Abstract translation: 提供了一种处理与电信网络中的电话会议业务有关的数据的方法。 电话会议服务能够为三个或更多的电话会议参与者处理多方电话会议。 第一，第二和第三电话会议参与标识符分别从第一，第二和第三电话会议参与者接收。 第一，第二和第三电话会议参与标识符被相关联以确定第一，第二和第三电话会议参与者是给定的多方电话会议中的参与者。 发送数据以便能够建立与电话会议分开设置的数据通信会话。 数据通信会话用于在与第一电话会议参与者相关联的第一数据通信设备，与第二电话会议参与者相关联的第二数据通信设备和与第三电话会议参与者相关联的第三数据通信设备之间进行数据通信。

公开(公告)号：US20090062307A1

公开(公告)日：2009-03-05

申请号：US12262290

申请日：2008-10-31

Applicant: Michael John Alberti ,  David Harold Drewry ,  David Drysdale Miller ,  Paul Bamborough

Inventor： Michael John Alberti ,  David Harold Drewry ,  David Drysdale Miller ,  Paul Bamborough

IPC: C07D409/14 ,  A61K31/497

CPC classification number: C07D471/04 ,  C07D403/04 ,  C07D409/14 ,  C07D473/00 ,  C07D487/04

Abstract: The present invention relates to aminopyrazine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such aminopyrazine derivatives are useful in the treatment of diseases associated with inappropriate tyrosine and/or serine/threonine kinase activity.

公开(公告)号：US06201129B1

公开(公告)日：2001-03-13

申请号：US08875667

申请日：1997-08-01

Applicant: David Drysdale Miller ,  Patrick Vivian Richard Shannon ,  Laddawan Chuncharprasert

Inventor： David Drysdale Miller ,  Patrick Vivian Richard Shannon ,  Laddawan Chuncharprasert

IPC: C07D48704

CPC classification number: C07D487/04

Abstract: A compound having the formula wherein R1 is COOR8 wherein R8 is alkyl having from 1 to 10 carbon atoms or aralkyl, the aralkyl having from one to four carbon atoms in the alkyl portion and a carbocyclic or heterocyclic group in the aryl portion; R2 is H, alkyl having from 1 to 10 carbon atoms, or COOR7 wherein R7 is alkyl having from 1 to 10 carbon atoms; R3 is H, alkyl having from 1 to 10 carbon atoms, or COOR8; R4 is H, alkyl having from 1 to 10 carbon atoms, or COOR8; R5 is H, alkyl having from 1 to 10 carbon atoms, aralkyl having from 1 to 4 carbon atoms in the alkyl portion, aryl having from 1 to 10 carbon atoms, acyl having from 1 to 10 carbon atoms, or COOCH3; and R6 is H or COOCH3; and thereof.

Abstract translation: 具有式R 1的化合物是COOR 8，其中R 8是具有1至10个碳原子的烷基或芳烷基，芳烷基中具有1至4个碳原子的芳烷基和芳基部分中的碳环或杂环基; R 2是H，烷基 具有1至10个碳原子，或COOR 7，其中R 7为具有1至10个碳原子的烷基; R 3为H，具有1至10个碳原子的烷基或COOR 8; R 4为H，具有1至10个碳原子的烷基 ，或COOR 8; R 5为H，具有1至10个碳原子的烷基，烷基部分具有1至4个碳原子的芳烷基，具有1至10个碳原子的芳基，具有1至10个碳原子的酰基，或COOCH 3 ; 和R6是H或COOCH 3;及其。