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公开(公告)号:US10292676B2
公开(公告)日:2019-05-21
申请号:US14367543
申请日:2012-12-20
申请人: Volcano Corporation , Nikhil Rajguru , Vladimir Zagrodsky , David Goodwin , Jon Klingensmith , Wolf-Ekkehard Blanz , Bernhard Sturm
发明人: Nikhil Rajguru , Vladimir Zagrodsky , David Goodwin , Jon Klingensmith , Wolf-Ekkehard Blanz , Bernhard Sturm
摘要: Computer-implemented methods for use in improving the diagnostic quality of images, including intravascular ultrasound (IVUS) images, are disclosed. The methods include using a non-linear, probabilistic classifier algorithm to analyze a plurality of spatiotemporal features of RF backscatter and to produce a blood likelihood map or blood probability map that corresponds to the original IVUS image. The methods disclosed herein allow for visualizing both static and dynamic characteristic of a vessel either by producing a transparency modulated color overlay of the blood likelihood map without altering the underlying IVUS image or by processing the IVUS image based upon the blood likelihood map to better distinguish between static and dynamic components of the vessel.
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公开(公告)号:US08008046B2
公开(公告)日:2011-08-30
申请号:US12335413
申请日:2008-12-15
CPC分类号: G01N21/645 , B01L3/50851 , B01L3/50853 , B01L7/52 , B01L7/54 , B01L2200/147 , B01L2300/0829 , B01L2300/0838 , B01L2300/12 , B01L2300/168 , B01L2300/1822 , B01L2300/1827 , B01L2300/185 , B01L2300/1861
摘要: This invention provides a method for carrying out nucleic acid amplification reactions involving heating and cooling of samples in sample vessels utilizing a heat block comprising a liquid. The method can be used to perform multiple nucleic acid amplification reactions simultaneously in which each of the reactions is performed so as to have temperature profiles. The apparatus can be used for performing PCR, and real time PCR in particular, with control and uniformity.
摘要翻译: 本发明提供了一种用于进行核酸扩增反应的方法,其涉及使用包含液体的热块加热和冷却样品容器中的样品。 该方法可以同时进行多个核酸扩增反应,其中进行每个反应以具有温度分布。 该装置可用于进行PCR,特别是具有控制和均匀性的实时PCR。
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公开(公告)号:US20100253769A1
公开(公告)日:2010-10-07
申请号:US12553890
申请日:2009-09-03
申请人: David A. Coppeta , James J. Zambuto , Ian Turner , David Goodwin , William Beck
发明人: David A. Coppeta , James J. Zambuto , Ian Turner , David Goodwin , William Beck
IPC分类号: H04N13/04 , G02F1/00 , G02B27/26 , G02B27/22 , G02F1/37 , H01S3/094 , G02B17/00 , G02B27/48 , B23P11/00 , F16M13/00
CPC分类号: G02F1/3532 , G02B27/1026 , G02B27/1046 , G02B27/1073 , G02B27/145 , G02B27/149 , G02B27/22 , G02B27/2264 , G02B27/26 , G02B27/286 , G02B27/48 , G02F1/37 , G02F1/39 , H01S3/005 , H01S3/0092 , H01S3/0606 , H01S3/0941 , H01S3/1611 , H01S3/23 , H01S3/2325 , H01S3/2383 , H01S3/2391 , H04N9/3105 , H04N9/3161 , H04N13/324 , H04N13/327 , H04N13/334 , H04N13/337 , H04N13/341 , H04N13/363 , Y10T29/49901
摘要: An optical system which includes some or all of the following parts: a laser light source which illuminates a spatial light modulator such that optical characteristics are preserved; a stereoscopic display which has a polarization-switching light source; a stereoscopic display which includes two infrared lasers, two optical parametric oscillators, and six second harmonic generators; two light sources processed by two parts of the same spatial light modulator; a method of assembly using an alignment plate to align kinematic rollers on a holding plate; an optical support structure which includes stacked, compartmented layers; a collimated optical beam between an optical parametric oscillator and a second harmonic generator; a laser gain module with two retroreflective mirrors; an optical tap which keeps the monitored beam co-linear; an optical coupler which includes an optical fiber and a rotating diffuser; and an optical fiber that has a core with at least one flat side.
摘要翻译: 一种包括以下部分或全部的光学系统:照射空间光调制器以使光学特性被保持的激光光源; 具有偏振切换光源的立体显示器; 包括两个红外激光器,两个光学参数振荡器和六个二次谐波发生器的立体显示器; 由相同空间光调制器的两部分处理的两个光源; 使用对准板来组装保持板上的运动辊的组装方法; 光学支撑结构,其包括层叠的隔层; 在光学参量振荡器和二次谐波发生器之间的准直光束; 具有两个回射反射镜的激光增益模块; 保持监测的光束共线的光学抽头; 包括光纤和旋转扩散器的光耦合器; 以及具有至少一个平坦侧的芯的光纤。
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公开(公告)号:US07736673B2
公开(公告)日:2010-06-15
申请号:US11259495
申请日:2005-10-26
申请人: Zoe Heaton , David Goodwin , Iain Breakwell
发明人: Zoe Heaton , David Goodwin , Iain Breakwell
IPC分类号: A61K9/14 , A01N45/00 , A61K31/715
CPC分类号: A61K9/0075 , A61K31/00 , A61K31/58 , A61M15/009 , A61M2202/064 , A61M2209/06 , B65D81/266
摘要: The invention relates to the use of an adsorbent and a sealed package, for example an overwrap, to protect a pharmaceutical product in a solid state in the presence of a reducing sugar.
摘要翻译: 本发明涉及吸附剂和密封包装(例如外包装)在还原糖存在下保护固体状态的药物的用途。
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公开(公告)号:US20100114941A1
公开(公告)日:2010-05-06
申请号:US12479646
申请日:2009-06-05
申请人: Tim A. VON KAENEL , David Neil DYRNAES , C. Suresh KUMAR , Jared Paul WAYMAN , Jonathan David GOODWIN , Craig Evan TRIVELPIECE , Joseph MIHALICH , Anthony Page JENKINS , Richard Hoyt ODOM, Jr. , Mark Andrew STIER , Anne Janetta OBEE
发明人: Tim A. VON KAENEL , David Neil DYRNAES , C. Suresh KUMAR , Jared Paul WAYMAN , Jonathan David GOODWIN , Craig Evan TRIVELPIECE , Joseph MIHALICH , Anthony Page JENKINS , Richard Hoyt ODOM, Jr. , Mark Andrew STIER , Anne Janetta OBEE
IPC分类号: G06F17/30
CPC分类号: G06F21/604 , G06F17/30 , G06F17/30241 , G06Q40/08 , Y10S707/99933 , Y10S707/99945 , Y10S707/99948
摘要: Disclosed is a method, system, and program for providing access to spatial data. A request for data is received. Enterprise and third party data are integrated. The integrated data is processed. Spatially referenced results are generated using the processed data. The spatially referenced results are returned in response to the request.
摘要翻译: 公开了一种用于提供对空间数据的访问的方法,系统和程序。 接收到数据请求。 企业和第三方数据整合。 处理集成数据。 使用处理后的数据生成空间参考的结果。 响应于请求返回空间参考的结果。
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公开(公告)号:US07662278B2
公开(公告)日:2010-02-16
申请号:US10410170
申请日:2003-04-10
IPC分类号: B01D29/62
CPC分类号: B01D29/055 , B01D29/668 , B01D29/70 , B01D29/705 , B01D29/902 , B01D2201/186
摘要: A self-cleaning assembly comprising an enclosed casing 1 with a movable piston 31 and filters 32,33 therein. The preferred assembly has a casing 1 with a dirty water inlet 5, a first outlet 6 for clean filtered water and a second outlet 7 for the removal of sludge from the casing. The filter assembly is constructed and arranged to provide, in its normal operating mode, a liquid flow path through the filter 32,33 in a first direction between the dirty water inlet 5 and the clean water outlet 6 and, in a cleaning mode, to provide a liquid flow path in a second direction between the dirty water inlet 5 and the sludge outlet 7. In the cleaning mode, the movable member 31 compresses the filters 32,33 during the liquid flow in the second direction and contaminant is released therefrom for removal from the filter assembly via the second outlet 7. In an alternative embodiment, the sludge outlet 7 is omitted and sludge is removed from the casing via the outlet 6.
摘要翻译: 一种自清洁组件,包括具有可移动活塞31的封闭壳体1和其中的过滤器32,33。 优选的组件具有带有脏水入口5的壳体1,用于清洁过滤水的第一出口6和用于从壳体去除污泥的第二出口7。 过滤器组件被构造和布置成在其正常操作模式中提供在脏水入口5和清洁水出口6之间沿着第一方向穿过过滤器32,33的液体流动路径,并且在清洁模式下, 在脏水入口5和污泥出口7之间沿第二方向提供液体流路。在清洁模式中,可移动部件31在第二方向的液体流动期间压缩过滤器32,33,并且从其中释放污染物 通过第二出口7从过滤器组件移除。在替代实施例中,省略了污泥出口7,并且通过出口6将污泥从壳体中移出。
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公开(公告)号:US20090026231A1
公开(公告)日:2009-01-29
申请号:US11666047
申请日:2005-10-13
申请人: David Goodwin
发明人: David Goodwin
IPC分类号: B67D3/00
CPC分类号: B65D47/283
摘要: A valve for a bottle or a bottle cap comprises a fluid delivery tube having an inlet and an outlet, the tube being moveable between a first position where fluid cannot enter the tube and a second position where fluid can enter the tube and means for urging the tube to the first position, wherein the tube is moveable to said second position by means of force applied in opposition to the urging means.
摘要翻译: 用于瓶或瓶盖的阀包括具有入口和出口的流体输送管,所述管可在流体不能进入管的第一位置和流体可以进入管的第二位置和用于推动所述管的装置之间移动 管到第一位置,其中管可以通过与施力装置相反施加的力而可移动到所述第二位置。
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公开(公告)号:US20060228244A1
公开(公告)日:2006-10-12
申请号:US10567806
申请日:2004-08-10
申请人: David Goodwin , Alan Saunders , Philip May , Graeme Huntley
发明人: David Goodwin , Alan Saunders , Philip May , Graeme Huntley
CPC分类号: F04C23/006 , F04C18/0215 , F04C18/0223 , F04C18/0269 , F04C2220/12 , F04C2250/101
摘要: The present invention is concerned with a scroll wall arrangement for a scroll compressor. The scroll wall arrangement comprises a fixed scroll having fixed scroll walls and an orbiting scroll having orbiting scroll wall. Scroll wall arrangement has an inlet at a radially outer portion thereof and an outlet at a radially central portion thereof. A first flow path is defined by the orbiting and fixed scroll walls and extends from the inlet to the outlet, gas entering the arrangement through inlet at a first pressure and exhausting through outlet at a second pressure higher than the first pressure. Scroll wall arrangement comprises a second inlet through which gas can enter at a third pressure and follow a second fluid path where it is exhausted through the outlet at the second pressure. Two flow paths are thus provided having respective inlets. The third pressure at which gas enters through inlet is different from the first pressure, and lower than the second pressure. Accordingly, the inlets can pump gas at different pressures.
摘要翻译: 本发明涉及涡旋压缩机的涡旋壁布置。 涡旋壁装置包括具有固定涡旋壁的固定涡旋盘和具有绕动涡旋壁的绕动涡旋盘。 涡卷壁布置在其径向外部具有入口,在其径向中心部分处具有出口。 第一流动路径由旋转和固定的涡旋壁限定,并且从入口延伸到出口,气体以第一压力进入入口并通过出口在高于第一压力的第二压力下排出。 涡旋壁布置包括第二入口,气体可以通过第二入口以第三压力进入并且跟随第二流体路径,在第二入口处,第二入口在第二压力下通过出口排出。 因此,提供了具有相应入口的两个流动路径。 气体通过入口进入的第三压力不同于第一压力,并且低于第二压力。 因此,入口可以泵送不同压力的气体。
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公开(公告)号:US20060147537A1
公开(公告)日:2006-07-06
申请号:US11259495
申请日:2005-10-26
申请人: Zoe Heaton , David Goodwin , Iain Breakwell
发明人: Zoe Heaton , David Goodwin , Iain Breakwell
IPC分类号: A61K31/573 , A61K9/14 , A61K31/7012 , A61K31/715
CPC分类号: A61K9/0075 , A61K31/00 , A61K31/58 , A61M15/009 , A61M2202/064 , A61M2209/06 , B65D81/266
摘要: The invention relates to the use of an adsorbent and a sealed package, for example an overwrap, to protect a pharmaceutical product in a solid state in the presence of a reducing sugar.
摘要翻译: 本发明涉及吸附剂和密封包装(例如外包装)在还原糖存在下保护固体状态的药物的用途。
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公开(公告)号:US07070845B2
公开(公告)日:2006-07-04
申请号:US10642262
申请日:2003-08-18
申请人: Edward N. Thomas , David Goodwin
发明人: Edward N. Thomas , David Goodwin
CPC分类号: A43B13/20 , B29C37/0082 , B29L2022/02 , B29L2031/502 , B29L2031/504 , D04B21/16 , D10B2403/0122 , D10B2403/021 , D10B2501/043 , Y10T428/231 , Y10T428/233 , Y10T428/23914
摘要: The invention relates to a fluid-filled bladder and a method for making for making a fluid-filled bladder that include a core having at least one fusing filament. A portion of the fusing filament is positioned adjacent to the exterior surface of the core such that it engages and fuses to barrier layers of the bladder, thereby securing the core to the barrier layers without the need for an additional fusing agent therebetween.
摘要翻译: 本发明涉及流体填充的气囊和一种用于制造流体填充气囊的方法,该气囊包括具有至少一个熔丝的芯。 定影丝的一部分定位成与芯的外表面相邻,使得其接合并熔合到囊的阻挡层,从而将芯固定到阻挡层,而不需要在其间的附加的熔合剂。
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