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    EXTRUSION SYSTEM FOR ADDITIVE MANUFACTURING AND 3-D PRINTING
    1.
    发明申请
    EXTRUSION SYSTEM FOR ADDITIVE MANUFACTURING AND 3-D PRINTING 审中-公开
    用于添加制造和三维打印的挤出系统

    公开(公告)号：US20150321419A1

    公开(公告)日：2015-11-12

    申请号：US14705940

    申请日：2015-05-06

    Applicant: Todd Linthicum ,  David Slade Simpson ,  Bryan Linthicum ,  Phillip Peterson

    Inventor： Todd Linthicum ,  David Slade Simpson ,  Bryan Linthicum ,  Phillip Peterson

    IPC: B29C67/00 ,  B29C47/60 ,  B29C47/66 ,  B29C47/38

    CPC classification number: B33Y30/00 ,  B29C48/02 ,  B29C48/397 ,  B29C48/505 ,  B29C48/681 ,  B29C64/106 ,  B29K2101/12 ,  B33Y10/00

    Abstract: The invention, and all of its embodiments, is a 3-D printer that utilizes one or more extrusion screws to process any given material including, but not limited to, plastic, metal, composites and non-metals to build 3-dimensional objects. The processed material is deposited on a moveable platform via force from the extrusion process. Motion is numerically controlled via a computer and one or more motors. As the extruder deposits material, a platform or the extruder is moved in one, two, or three dimensions at a predetermined vector. Once a layer of the object is created, the distance between the extruder nozzle and print surface is increased and the process is repeated until a three dimensional shape is created.

    Abstract translation: 本发明及其所有实施例是三维打印机，其利用一个或多个挤出螺钉来处理包括但不限于塑料，金属，复合材料和非金属的任何给定材料以构建3维物体。 经处理的材料通过来自挤出过程的力沉积在可移动平台上。 运动通过计算机和一个或多个电机进行数字控制。 当挤出机沉积材料时，平台或挤出机以一个，两个或三个维度以预定的载体移动。 一旦创建了一个对象层，挤出机喷嘴和打印表面之间的距离就会增加，重复该过程，直到产生三维形状。

    Desiccated analogs of botanic seed
    3.
    发明授权
    Desiccated analogs of botanic seed 失效
    植物种子的干燥类似物

    公开(公告)号：US4777762A

    公开(公告)日：1988-10-18

    申请号：US946062

    申请日：1986-12-24

    Applicant: M. Keith Redenbaugh ,  David Slade ,  Jo A. Fujii

    Inventor： M. Keith Redenbaugh ,  David Slade ,  Jo A. Fujii

    IPC: A01C1/00 ,  A01C1/06 ,  A01G1/00 ,  A01H4/00 ,  A01N37/42 ,  A01N43/16

    CPC classification number: A01H4/00 ,  Y10S47/09

    Abstract: Methods and materials are provided for desiccated analogs of botanic seeds which are created by removing a portion of the water by slow or fast drying so that the plant tissue is no longer saturated with water. In a second embodiment, the meristematic tissue is encapsulated in a gel or polymer followed by dehydration. In another embodiment, the meristematic tissue is dehydrated prior to encapsulation in a gel. Protectants can be incorporated in the gel capsule. Meristematic tissue can be isolated from, for example, somatic embryos, zygotic and germ line sources.

    Abstract translation: 为植物种子的干燥类似物提供了方法和材料，通过缓慢或快速干燥除去一部分水而使植物组织不再饱和。 在第二实施方案中，分生组织被包封在凝胶或聚合物中，然后脱水。 在另一个实施方案中，将分生组织在包封在凝胶中之前脱水。 保护剂可以并入凝胶胶囊中。 分生组织可以从例如体细胞胚，合子和种系来源分离。

    Cytoskeletal active compounds, compositions and use
    5.
    发明申请
    Cytoskeletal active compounds, compositions and use 失效
    细胞骨架活性化合物，组合物和用途

    公开(公告)号：US20060217427A1

    公开(公告)日：2006-09-28

    申请号：US11389665

    申请日：2006-03-23

    Applicant: John Lampe ,  Robert Plourde ,  Jin She ,  Jason Vittitow ,  Paul Watson ,  Michael Crimmins ,  David Slade

    Inventor： John Lampe ,  Robert Plourde ,  Jin She ,  Jason Vittitow ,  Paul Watson ,  Michael Crimmins ,  David Slade

    IPC: A61K31/426 ,  A61K31/422 ,  A61K31/4178 ,  C07D413/02 ,  C07D417/02 ,  C07D405/02

    CPC classification number: C07D491/08 ,  C07D277/06 ,  C07D277/14 ,  C07D277/16 ,  C07D277/34 ,  C07D277/56 ,  C07D417/04 ,  C07D493/08 ,  C07D497/18

    Abstract: The present invention is directed to synthetic cytoskeletal active compounds that are related to natural Latrunculin A or Latrunculin B. The present invention is also directed to pharmaceutical compositions comprising such compounds and a pharmaceutically acceptable carrier. The invention is additionally directed to a method of preventing or treating diseases or conditions associated with actin polymerization. In one embodiment of the invention, the method treats increased intraocular pressure, such as primary open-angle glaucoma. The method comprises administering to a subject a therapeutically effective amount of a cytoskeletal active compound of Formula I or II, wherein said amount is effective to influence the cytoskeleton, for example by inhibiting actin polymerization.

    Abstract translation: 本发明涉及与天然的秋水仙素A或梭菌素B相关的合成细胞骨架活性化合物。本发明还涉及包含这些化合物和药学上可接受的载体的药物组合物。 本发明另外涉及预防或治疗与肌动蛋白聚合相关的疾病或病症的方法。 在本发明的一个实施方案中，该方法治疗增加的眼内压，例如原发性开角型青光眼。 该方法包括向受试者施用治疗有效量的式I或II的细胞骨架活性化合物，其中所述量有效影响细胞骨架，例如通过抑制肌动蛋白聚合。

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