摘要:
A biomedical device surface, such as a contact lens surface, is covalently linked to a cationic copolymer. The copolymer may include monomeric units derived from an ethylenically unsaturated monomer containing a quaternary ammonium moiety and monomeric units derived from an ethylenically unsaturated monomer containing a moiety reactive with complementary reactive functionalities at the lens surface. The copolymer may be covalently linked directly to the lens surface, or covalently linked with an intermediate polymer reactive with both the lens surface and the copolymer.
摘要:
A process for removing contaminants and/or leachables from polymeric materials useful in the manufacture of biocompatible medical devices such as intraocular lenses, corneal inlays and contact lenses using continuous soxhlet extraction.
摘要:
A method of producing a mixture or solution of a liquid and a fusible solid comprises providing, in a container, the liquid and the fusible solid; and subjecting the container to a rotational motion about a first axis in a first direction while rotating the container about a second axis in a second direction to effect a dissolution of the fusible solid and a mixing of the components of the mixture or solution.
摘要:
A method of producing and simultaneously deaerating a mixture comprises providing, in a container, components of the mixture; and subjecting the container to a rotational motion about a first axis in a first direction while rotating the container about a second axis in a second direction to effect a mixing and a substantially simultaneous deaeration.
摘要:
A biomedical device, such as a contact lens, has a surface linked to a polymer comprising boronic acid moieties. The boronic acid monomeric units may be derived from an ethylenically unsaturated monomer containing a boronic acid moiety, such as a vinylphenyl boronic acid or a (meth)acrylamido phenyl boronic acid. The boronic acid moieties may be complexed with mucin, especially epithelial mucin.
摘要:
A method for limiting a transfer of an additive in a first polymeric article to a second adjacent polymeric article comprises treating at least a portion of the first article under a condition such that the additive is transformed to a substantially stable phase. A polymeric article comprises a compounded polymeric material that comprises an additive in a base polymeric material, wherein the additive exists in a substantially stable phase.
摘要:
This invention is directed toward interactive segmented block copolymers useful to treat the surface of a substrate by means of interactive functionalities of the interactive segmented block copolymer material binding with complementary surface functionalities of the polymer substrate.
摘要:
Methods for enhancing the lubricity of implant delivery devices are provided. The present methods of enhancing the lubricity of an intraocular lens inserter reduce the force required to express an intraocular lens therefrom. By reducing the force required to express an intraocular lens from an inserter, intraocular lens delivery is improved.
摘要:
A method of producing a mixture comprises providing, in a container, at least a first component of the mixture at a first temperature; adding a remaining component of the mixture to said at least a first component; subjecting the container to a rotational motion about a first axis in a first direction while rotating the container about a second axis in a second direction to effect a mixing; wherein the first temperature is lower than the temperature of the mixture at the end of the mixing.