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    SPINNING DEVICE
    1.
    发明申请
    SPINNING DEVICE 审中-公开
    纺纱装置

    公开(公告)号：US20160367953A1

    公开(公告)日：2016-12-22

    申请号：US14744791

    申请日：2015-06-19

    申请人： Rachel First

    发明人： Rachel First

    IPC分类号： B01F9/00

    CPC分类号： B01F9/003 ,  B01F9/04 ,  B01F15/00746

    摘要： A spinning device automates the spinning of a composition, such as insulin, in a container. The device creates a slow, uniform spinning motion while securely retaining the container. This helps eliminate the conditions of dropping the container, or excessive agitations to the composition that create air bubble. A bifurcated housing includes a motor region having a motor, and a spin region having a clasp portion. A shaft connects the motor to the clasp portion thus spinning the clasp portion. The spin region is covered by a transparent observation door. The motor region includes a control portion with a power switch, a light emitting diode, and a digital display with a power-indicating light. The clasp portion is C-shaped and spring biased inwardly to secure the container. An inner grip layer overlays the clasp portion to inhibit slippage. A spin regulator maintains the container in an upright position.

    摘要翻译： 旋转装置使诸如胰岛素的组合物在容器中自动化。 该装置在牢固地保持容器的同时产生缓慢且均匀的旋转运动。 这有助于消除容器掉落的条件，或过度搅动产生气泡的组合物。 分叉壳体包括具有马达的马达区域和具有扣环部分的自旋区域。 轴将电动机连接到扣环部分，从而旋转扣环部分。 旋转区域被透明观察门覆盖。 马达区域包括具有电源开关的控制部分，发光二极管和具有电力指示灯的数字显示器。 扣环部分为C形，弹簧向内偏压以固定容器。 内夹层覆盖扣环部分以抑制滑动。 旋转调节器将容器保持在直立位置。

    Spectrometric characterization of pharmaceutical heterogeneity
    2.
    发明授权
    Spectrometric characterization of pharmaceutical heterogeneity 有权
    药物异质性的光谱测定

    公开(公告)号：US07864316B2

    公开(公告)日：2011-01-04

    申请号：US11986548

    申请日：2007-11-20

    申请人： E. Neil Lewis ,  Kenneth S. Haber

    发明人： E. Neil Lewis ,  Kenneth S. Haber

    IPC分类号： G01J3/28

    CPC分类号： G01J3/06 ,  B01F9/04 ,  B01F15/00207 ,  B01F15/00214 ,  B01F2215/0032 ,  G01J3/0218 ,  G01J3/42 ,  G01N21/03 ,  G01N21/35 ,  G01N21/3577 ,  G01N21/85 ,  G01N21/9508 ,  G01N2021/3595 ,  G01N2021/8592

    摘要： In one general aspect, a spectroscopic method for monitoring heterogeneity of a sample is disclosed. In this method, sampled spectroscopic measurements are acquired over a range of different micro locations in a macro-sample of the sample. This step is repeated for micro-locations in further macro-samples of the sample, and a statistical measure of chemical heterogeneity is derived from the acquisitions. In another general aspect, differently sized samples are acquired, and a statistical measure of chemical heterogeneity is derived from these acquisitions.

    摘要翻译： 在一般的方面，公开了一种用于监测样品异质性的光谱方法。 在该方法中，在样本的宏观样本中的不同微位置的范围上获取采样的光谱测量。 对于样品的其他宏观样品中的微位置重复此步骤，并且从采集中得出化学异质性的统计量度。 在另一个一般方面，获得不同大小的样品，并且从这些获取中得出化学异质性的统计量度。

    Method for coating medical devices
    3.
    发明授权
    Method for coating medical devices 有权
    医疗器械涂层方法

    公开(公告)号：US07781010B2

    公开(公告)日：2010-08-24

    申请号：US11449090

    申请日：2006-06-08

    申请人： Marian L. Larson ,  Eugene A. Larson

    发明人： Marian L. Larson ,  Eugene A. Larson

    IPC分类号： B05C3/00 ,  B05C19/02 ,  B05D3/00

    CPC分类号： A61F2/30767 ,  A61F2/0077 ,  A61F2/24 ,  A61F2/3094 ,  A61F2/3662 ,  A61F2/38 ,  A61F2240/001 ,  A61F2310/00796 ,  A61F2310/0097 ,  B01F9/04 ,  B01F15/0266

    摘要： An apparatus for coating medical devices at the point of care with a polymer and/or therapeutic agent comprising an environmentally controlled device coating chamber in which the device may be delivered by the manufacturer as the device packaging, or the device may be placed into the chamber at the point of care. The environmentally controlled chamber can provide a sterile enclosure in which the polymer and/or a therapeutic agent can be applied to an uncoated or previously coated device and converted to another form (such as a liquid to a film or gel) if desired, under controlled and reproducible conditions. The environmentally controlled chamber can accommodate and provide for coating the device by immersion, spray and other methods of covering the device surface with a liquid or powder. The chamber can provide for energy sources, both internally, such as heat produced by film heaters, and externally, such as UV light or microwave passing through the enclosure. The chamber may allow for changes in atmosphere to affect the coating, such as the introduction of certain gases and introducing pressure or vacuum.

    摘要翻译： 一种用于通过聚合物和/或治疗剂涂覆医疗装置的装置，其包括环境受控的装置涂覆室，其中装置可以由制造商作为装置包装递送，或者该装置可以放置在室中 在护理点。 环境控制的室可以提供无菌外壳，其中聚合物和/或治疗剂可以施用于未涂覆或预先涂覆的装置，并且如果需要，在受控的情况下转化成另一种形式（例如液体到膜或凝胶） 和可再现的条件。 环境控制的室可以容纳并提供通过浸没，喷雾和用液体或粉末覆盖装置表面的其它方法来涂覆装置。 该室可以在内部提供能量源，例如由薄膜加热器产生的热量，以及外部，例如通过外壳的UV光或微波。 该室可以允许大气的变化影响涂层，例如引入某些气体并引入压力或真空。

    Apparatus for coating medical devices
    4.
    发明授权
    Apparatus for coating medical devices 失效
    医疗器械涂层装置

    公开(公告)号：US07585369B2

    公开(公告)日：2009-09-08

    申请号：US11021656

    申请日：2004-12-23

    申请人： Marian L. Larson ,  Eugene A Larson

    发明人： Marian L. Larson ,  Eugene A Larson

    IPC分类号： B05C3/08

    CPC分类号： A61F2/30767 ,  A61F2/0077 ,  A61F2/24 ,  A61F2/3094 ,  A61F2/3662 ,  A61F2/38 ,  A61F2240/001 ,  A61F2310/00796 ,  A61F2310/0097 ,  B01F9/04 ,  B01F15/0266

    摘要： An apparatus for coating medical devices at the point of care with a polymer and/or therapeutic agent comprising an environmentally controlled device coating chamber in which the device may be delivered by the manufacturer as the device packaging, or the device may be placed into the chamber at the point of care. The environmentally controlled chamber can provide a sterile enclosure in which the polymer and/or a therapeutic agent can be applied to an uncoated or previously coated device and converted to another form (such as a liquid to a film or gel) if desired, under controlled and reproducible conditions. The environmentally controlled chamber can accommodate and provide for coating the device by immersion, spray and other methods of covering the device surface with a liquid or powder. The chamber can provide for energy sources, both internally, such as heat produced by film heaters, and externally, such as UV light or microwave passing through the enclosure. The chamber may allow for changes in atmosphere to affect the coating, such as the introduction of certain gases and introducing pressure or vacuum.

    摘要翻译： 一种用于通过聚合物和/或治疗剂涂覆医疗装置的装置，其包括环境受控的装置涂覆室，其中装置可以由制造商作为装置包装递送，或者该装置可以放置在室中 在护理点。 环境控制的室可以提供无菌外壳，其中聚合物和/或治疗剂可以施用于未涂覆或预先涂覆的装置，并且如果需要，在受控的情况下转化成另一种形式（例如液体到膜或凝胶） 和可再现的条件。 环境控制的室可以容纳并提供通过浸没，喷雾和用液体或粉末覆盖装置表面的其它方法来涂覆装置。 该室可以在内部提供能量源，例如由薄膜加热器产生的热量，以及外部，例如通过外壳的UV光或微波。 该室可以允许大气的变化影响涂层，例如引入某些气体并引入压力或真空。

    Spectroscopic analyzer for blender
    5.
    发明授权
    Spectroscopic analyzer for blender 有权
    搅拌机光谱分析仪

    公开(公告)号：US07075645B2

    公开(公告)日：2006-07-11

    申请号：US10426980

    申请日：2003-04-30

    申请人： Lane Gehrlein ,  Emil Ciurczak ,  Gary Ritchie

    发明人： Lane Gehrlein ,  Emil Ciurczak ,  Gary Ritchie

    IPC分类号： G01J3/28 ,  B01F9/00

    CPC分类号： B01F9/04 ,  B01F3/02 ,  B01F9/005 ,  B01F15/00207

    摘要： A blending apparatus comprises a blender including a container having a wall, the wall including a window. The container rotates about an axis of rotation. A wireless spectrometer is mounted to the container and operates through the window, in a direction that does not intersect the axis of rotation, for obtaining a set of spectroscopic data regarding the product during an operation of the blender. In addition, a method for assaying a blended product in a blender includes mounting a wireless spectrometer to the container, rotating the container about its axis of rotation so as to blend the product; operating the wireless spectrometer through a window in the container, in a direction that does not intersect the axis of rotation, to obtain spectroscopic data regarding the product during the blending, and determining a homogeneity of the product from the spectroscopic data.

    摘要翻译： 混合装置包括一个包括一个具有一个壁的容器的搅拌器，该墙壁包括一个窗户。 容器围绕旋转轴线旋转。 将无线光谱仪安装到容器上，并且在与旋转轴线不相交的方向上通过窗口操作，以在搅拌器的操作期间获得关于产品的一组光谱数据。 此外，用于在混合器中测定混合产品的方法包括将无线光谱仪安装到容器上，使容器围绕其旋转轴线旋转以便混合产品; 通过容器中的窗口沿不与旋转轴线相交的方向操作无线光谱仪，以获得关于混合期间产品的光谱数据，以及根据光谱数据确定产品的均匀性。

    Mixing apparatus and method
    7.
    发明申请
    Mixing apparatus and method 失效
    混合装置和方法

    公开(公告)号：US20040165475A1

    公开(公告)日：2004-08-26

    申请号：US10790703

    申请日：2004-03-03

    申请人： AstraZeneca UK Limited

    发明人： Ali Mohammad Afnan ,  Robert Symes Chisholm

    IPC分类号： B01F015/00

    CPC分类号： B01F9/0018 ,  B01F7/00908 ,  B01F9/0005 ,  B01F9/0043 ,  B01F9/005 ,  B01F9/04 ,  B01F11/0017 ,  B01F13/0035 ,  B01F15/00207 ,  B01F2215/0032 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/359

    摘要： Apparatus for mixing a number of components comprising a vessel for receiving the components, drive means for rotating or oscillating the vessel about an axis to effect mixing of the components within the vessel, and at least one spectroscopic monitoring means for repeatedly scanning the mixture to obtain data for use in monitoring changes in the spectroscopic profile of the mixture as mixing proceeds, the monitoring means by mounted off-axis relative to the axis about which the vessel is rotatable or oscillatable.

    摘要翻译： 用于混合包括用于接收部件的容器的多个部件的装置，用于围绕轴旋转或振荡容器以实现容器内的部件的混合的驱动装置和用于反复扫描混合物以获得的至少一个光谱监测装置 用于监测混合物随着混合进行的光谱轮廓变化的数据，所述监测装置通过相对于所述容器可旋转或可摆动的轴离轴设置。

    Racetrack-shaped dynamic gravity flow blender
    8.
    发明授权
    Racetrack-shaped dynamic gravity flow blender 有权
    赛道式动力式重力流动搅拌机

    公开(公告)号：US06494612B2

    公开(公告)日：2002-12-17

    申请号：US09805749

    申请日：2001-03-13

    申请人： Jerry R. Johanson

    发明人： Jerry R. Johanson

    IPC分类号： B01F524

    CPC分类号： B01F5/24 ,  B01F3/08 ,  B01F3/18 ,  B01F5/247 ,  B01F9/04 ,  B01F15/0267 ,  B01F2009/0087

    摘要： Apparatus for blending particulate solids or liquids includes a blending vessel having a racetrack-shaped cross section at each elevation above its lower end. The racetrack-shaped cross section consists of two spaced opposed semicircles having ends that are joined by two spaced parallel line segments. Several embodiments of the apparatus are described; they all employ the racetrack-shaped blending vessel, which is highly effective in promoting mixing. In one embodiment the racetrack-shaped blending vessel is rotated about a horizontal axis so that the material passes through the vessel on each revolution. In another embodiment, a number of racetrack-shaped blending vessels are connected in a vertical sequence so that the material must pass through the blending vessels in succession.

    摘要翻译： 用于混合颗粒固体或液体的装置包括在其下端上方的每个高度处具有跑道形横截面的混合容器。 跑道形横截面由两个间隔开的相对的半圆形部分组成，其端部由两个间隔开的平行线段连接起来。 描述该装置的几个实施例; 他们都采用赛马场混合容器，这对搅拌是非常有效的。 在一个实施例中，跑道形混合容器围绕水平轴旋转，使得材料在每次旋转时通过容器。 在另一个实施例中，多个跑道状混合容器以垂直顺序连接，使得材料必须连续通过混合容器。

    Racetrack-shaped dynamic gravity flow blender
    9.
    发明申请
    Racetrack-shaped dynamic gravity flow blender 有权

    公开(公告)号：US20020159329A1

    公开(公告)日：2002-10-31

    申请号：US09805749

    申请日：2001-03-13

    发明人： Jerry R. Johanson

    IPC分类号： B01F005/24 ,  B01F009/02

    CPC分类号： B01F5/24 ,  B01F3/08 ,  B01F3/18 ,  B01F5/247 ,  B01F9/04 ,  B01F15/0267 ,  B01F2009/0087

    摘要： Apparatus for blending particulate solids or liquids includes a blending vessel having a racetrack-shaped cross section at each elevation above its lower end. The racetrack-shaped cross section consists of two spaced opposed semicircles having ends that are joined by two spaced parallel line segments. Several embodiments of the apparatus are described; they all employ the racetrack-shaped blending vessel, which is highly effective in promoting mixing. In one embodiment the racetrack-shaped blending vessel is rotated about a horizontal axis so that the material passes through the vessel on each revolution. In another embodiment, a number of racetrack-shaped blending vessels are connected in a vertical sequence so that the material must pass through the blending vessels in succession.