Control of reactor environmental conditions
    6.
    发明申请
    Control of reactor environmental conditions 审中-公开
    控制反应堆环境条件

    公开(公告)号:US20060019333A1

    公开(公告)日:2006-01-26

    申请号:US11146920

    申请日:2005-06-07

    IPC分类号: C12P1/00

    摘要: The present disclosure generally relates to chemical, biological, and/or biochemical reactor chips and/or reaction systems such as microreactor systems, as well as methods for constructing and using such systems. In some cases, humidity control materials are utilized to provide beneficially high rates of gas exchange. The humidity control materials may be used, in certain instances, to provide at least adequate, and in certain embodiments superior, gas exchange for systems having small volumes. In some cases, the currently disclosed materials include certain polymers, e.g., poly(acetylene)s such as poly(alkylacetylene)s. The polymers may be at least partially halogenated (for example, fluorinated) in some instances. In certain embodiments, a chip and/or a reaction system may be constructed so as to promote cell growth within it. In some embodiments, the chips may include one or more reaction sites. The reaction sites can be very small, for example, with a volume of less than about 1 ml. In certain embodiments, a reaction system is able to detect, measure and/or control an environmental factor such as the temperature, pressure, CO2 concentration, O2 concentration, relative humidity, pH, etc., associated with one or more reaction sites, by using one or more sensors, actuators, processors, and/or control systems. In certain embodiments, the present disclosure discloses materials and systems having humidity and/or gas control, for example, for use with a reaction system. Such materials may have high oxygen permeability and/or low water vapor permeability. In certain embodiments, the disclosed devices can employ light-interacting components suitable for use in reaction systems. These components may include waveguides, optical fibers, light sources, photodetectors, optical elements, and the like.

    摘要翻译: 本公开一般涉及化学,生物和/或生化反应堆芯片和/或反应系统,例如微反应器系统,以及用于构建和使用这种系统的方法。 在一些情况下,使用湿度控制材料来提供有利的高比例的气体交换。 在某些情况下,可以使用湿度控制材料,以在具有小体积的系统中提供至少足够的且在某些实施方案中优异的气体交换。 在一些情况下,目前公开的材料包括某些聚合物,例如聚(乙炔)如聚(烷基乙炔)。 在某些情况下,聚合物可以至少部分卤化(例如氟化)。 在某些实施方案中,可以构建芯片和/或反应系统以促进细胞内的细胞生长。 在一些实施方案中,芯片可以包括一个或多个反应位点。 反应位点可以非常小,例如,体积小于约1ml。 在某些实施方案中,反应体系能够检测,测量和/或控制环境因素,例如温度,压力,CO 2浓度,O 2 O 2浓度,相对 通过使用一个或多个传感器,致动器,处理器和/或控制系统与一个或多个反应位点相关的湿度,湿度,pH等。 在某些实施方案中,本公开公开了具有例如用于反应体系的湿度和/或气体控制的材料和系统。 这样的材料可以具有高氧渗透性和/或低水蒸汽渗透性。 在某些实施方案中,所公开的装置可以使用适合用于反应体系的光相互作用组分。 这些组件可以包括波导,光纤,光源,光电检测器,光学元件等。