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1.发明授权公开(公告)号：US07772398B2
公开(公告)日：2010-08-10
申请号：US11079881
申请日：2005-03-11
IPC分类号： C07D495/04
CPC分类号： C07D495/04
摘要： A process for preparation of crystalline Form I of clopidogrel hydrogen sulphate, that include separating the crystalline Form I of clopidogrel hydrogen sulphate from a solution of clopidogrel freebase in a solvent, which is 2-propanol or 2-butanol is provided.
摘要翻译： 提供氯吡格雷硫酸氢盐的结晶形式I的制备方法，其包括将氯吡格雷硫酸氢盐的结晶形式I从氯吡格雷游离碱的溶液分离在2-丙醇或2-丁醇的溶剂中。
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公开(公告)号：US20070197535A1
公开(公告)日：2007-08-23
申请号：US11535704
申请日：2006-09-27
申请人： Eswaraiah Sajja , Ravindar Koppera , Satyanarayana Revu , Venkata Vajrala , Vijayapal Kanumathi
发明人： Eswaraiah Sajja , Ravindar Koppera , Satyanarayana Revu , Venkata Vajrala , Vijayapal Kanumathi
IPC分类号： A61K31/53 , C07D487/04
CPC分类号： C07D487/04
摘要： Crystalline polymorphic forms of vardenafil and vardenafil hydrochloride, and processes for preparing them.
摘要翻译： 伐地那非和伐地那非盐酸盐的结晶多晶型物及其制备方法。
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3.发明申请公开(公告)号：US20060205766A1
公开(公告)日：2006-09-14
申请号：US11079881
申请日：2005-03-11
IPC分类号： A61K31/4743 , C07D498/02
CPC分类号： C07D495/04
摘要： A process for preparation of crystalline Form I of clopidogrel hydrogen sulphate, that include separating the crystalline Form I of clopidogrel hydrogen sulphate from a solution of clopidogrel freebase in a solvent, which is 2-propanol or 2-butanol is provided.
摘要翻译： 提供氯吡格雷硫酸氢盐的结晶形式I的制备方法，其包括将氯吡格雷硫酸氢盐的结晶形式I从氯吡格雷游离碱的溶液分离在2-丙醇或2-丁醇的溶剂中。
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公开(公告)号：US11261160B2
公开(公告)日：2022-03-01
申请号：US16467853
申请日：2017-12-06
申请人： MSN LABORATORIES PRIVATE LIMITED, R&D CENTER , Thirumalai Rajan Srinivasan , Eswaraiah Sajja , Venkata Panakala Rao Gogulapati , Rajeshwar Reddy Sagyam , Shyam Kiran Babu Gandham , Rajesham Boge
发明人： Thirumalai Rajan Srinivasan , Eswaraiah Sajja , Venkata Panakala Rao Gogulapati , Rajeshwar Reddy Sagyam , Shyam Kiran Babu Gandham , Rajesham Boge
IPC分类号： C07D215/233
摘要： The present invention also relates to process for the preparation of N-(4-(6,7-dimethoxy quinolin-4-yloxy)phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-malate compound of formula-1a and its polymorphs thereof, represented by the following structural:
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公开(公告)号：US20210403431A1
公开(公告)日：2021-12-30
申请号：US16467853
申请日：2017-12-06
申请人： THIRUMALAI RAJAN RAJAN Srinivasan , ESWARAIAH Sajja , VENKATA PANAKALA RAO Gogulapati , RAJESHWAR REDDY Sagyam , SHYAM KIRAN BABU Gandham , RAJESHAM Boge , MSN LABORATORIES PRIVATE LIMITED, R&D CENTER
发明人： THIRUMALAI RAJAN SRINIVASAN , ESWARAIAH SAJJA , VENKATA PANAKALA RAO GOGULAPATI , RAJESHWAR REDDY SAGYAM , SHYAM KIRAN BABU GANDHAM , RAJESHAM BOGE
IPC分类号： C07D215/233
摘要： The present invention also relates to process for the preparation of N-(4-(6,7-dimethoxy quinolin-4-yloxy)phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-malate compound of formula-1a and its polymorphs thereof, represented by the following structural:
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公开(公告)号：US07977478B2
公开(公告)日：2011-07-12
申请号：US11535704
申请日：2006-09-27
申请人： Eswaraiah Sajja , Ravindar Reddy Koppera , Satyanarayana Revu , Venkata Reddy Vajrala , Vijayapal Reddy Kanumathi
发明人： Eswaraiah Sajja , Ravindar Reddy Koppera , Satyanarayana Revu , Venkata Reddy Vajrala , Vijayapal Reddy Kanumathi
IPC分类号： C07D487/04 , A61K31/53 , A61P15/10
CPC分类号： C07D487/04
摘要： Crystalline polymorphic forms of vardenafil and vardenafil hydrochloride, and processes for preparing them.
摘要翻译： 伐地那非和伐地那非盐酸盐的结晶多晶型物及其制备方法。
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公开(公告)号：US20070098788A1
公开(公告)日：2007-05-03
申请号：US11553342
申请日：2006-10-26
申请人： Subhash Gore , Sudeep Agrawal , Abhijeet Upadhye , Srinivasulu Rangineni , Sivakumar Bommareddy , Srinivas Gade , Basappa Nagaraj , Gautam Bakshi , Surjit Das , Satish Jain , Surya Devarakonda , Bharath Deevireddy , Eswaraiah Sajja , Venkata Naga Kali Veturi , Sreenadhacharyulu Kandala , Gurvinder Singh , Indu Bhushan , Mailatur Mohan
发明人： Subhash Gore , Sudeep Agrawal , Abhijeet Upadhye , Srinivasulu Rangineni , Sivakumar Bommareddy , Srinivas Gade , Basappa Nagaraj , Gautam Bakshi , Surjit Das , Satish Jain , Surya Devarakonda , Bharath Deevireddy , Eswaraiah Sajja , Venkata Naga Kali Veturi , Sreenadhacharyulu Kandala , Gurvinder Singh , Indu Bhushan , Mailatur Mohan
IPC分类号： A61K31/519 , A61K9/20
CPC分类号： A61K9/1664 , A61K9/146 , A61K9/1635 , A61K9/2013 , A61K9/205 , A61K31/519
摘要： Pharmaceutical compositions comprising non-benzodiazepine hypnotic drugs or their pharmaceutically acceptable salts, solvates, enantiomers or mixtures and processes for preparing the same. The invention also includes immediate release and extended release pharmaceutical compositions comprising non-benzodiazepine hypnotic drugs, useful for sleep induction and sleep maintenance.
摘要翻译： 包含非苯并二氮卓催眠药物或其药学上可接受的盐，溶剂合物，对映异构体或混合物的药物组合物及其制备方法。 本发明还包括用于睡眠诱导和睡眠维持的包含非苯二氮卓催眠药物的立即释放和缓释药物组合物。
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公开(公告)号：US20050272787A1
公开(公告)日：2005-12-08
申请号：US11133000
申请日：2005-05-19
申请人： Eswaraiah Sajja , Anumula Reddy , Aalla Sampath , Gilla Goverdhan
发明人： Eswaraiah Sajja , Anumula Reddy , Aalla Sampath , Gilla Goverdhan
IPC分类号： A61K31/42 , C07D261/06 , C07D261/08
CPC分类号： C07D261/08
摘要： Valdecoxib Form A is prepared by a process comprising adding aqueous ammonia to a solution of 4-(5-methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl chloride in a halogenated hydrocarbon or water.
摘要翻译： 通过包括向4-（5-甲基-3-苯基-4-异恶唑基）苯磺酰氯在卤代烃或水中的溶液中加入氨水的方法制备瓦尔多昔单抗A型。
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公开(公告)号：US08063214B2
公开(公告)日：2011-11-22
申请号：US11577948
申请日：2005-10-26
申请人： Eswaraiah Sajja , Venkata Naga Kali Vara Prasada Raju Vetukuri , Srinivas Reddy Ningam , Ravindra Vedantham , Rajyalakshmi Bodepudi
发明人： Eswaraiah Sajja , Venkata Naga Kali Vara Prasada Raju Vetukuri , Srinivas Reddy Ningam , Ravindra Vedantham , Rajyalakshmi Bodepudi
IPC分类号： C07D471/00 , C07D493/00
CPC分类号： C07D471/14
摘要： A process for preparing crystalline Form A of tadalafil (I), comprising crystallization from a solution of tadalafil in a solvent comprising a C3-C7 ester, a ketone, dimethylformamide, dimethylsulfoxide, ethanol, acetonitrile, a chlorinated hydrocarbon, t-butanol, N,N-dimethylacetamide, dioxane, N-methyl pyrrolidone, or a mixture of any two or more thereof.
摘要翻译： 一种制备他达拉非（I）结晶形式A的方法，包括由他达拉非溶液在包含C3-C7酯，酮，二甲基甲酰胺，二甲基亚砜，乙醇，乙腈，氯化烃，叔丁醇，N ，N-二甲基乙酰胺，二恶烷，N-甲基吡咯烷酮，或其任意两种以上的混合物。
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公开(公告)号：US20090131667A1
公开(公告)日：2009-05-21
申请号：US11577948
申请日：2005-10-26
申请人： Eswaraiah Sajja , Venkata Naga Kali Vara Prasada Raju Vetukuri , Srinivas Reddy Ningam , Ravindra Vedantham , Rajyalakshmi Bodepudi
发明人： Eswaraiah Sajja , Venkata Naga Kali Vara Prasada Raju Vetukuri , Srinivas Reddy Ningam , Ravindra Vedantham , Rajyalakshmi Bodepudi
IPC分类号： C07D405/14
CPC分类号： C07D471/14
摘要： Polymorphic forms of tadalafil, and processes for their preparation.
摘要翻译： 他达拉非的多形态及其制备方法。
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