公开(公告)号：US20110207746A1

公开(公告)日：2011-08-25

申请号：US13062318

申请日：2009-09-16

Applicant: Edward Daniel Savory ,  Michael Higginbottom ,  Kathryn Oliver ,  VietAnh Anne Horgan

Inventor： Edward Daniel Savory ,  Michael Higginbottom ,  Kathryn Oliver ,  VietAnh Anne Horgan

IPC: A61K31/497 ,  C07D471/04 ,  A61K31/437 ,  A61P29/00 ,  A61P37/06 ,  A61P19/02 ,  A61P25/28 ,  A61P1/00 ,  A61P9/10 ,  A61P11/06 ,  A61P11/00 ,  A61P9/00 ,  A61P17/00 ,  A61P17/06 ,  A61P1/16 ,  A61P3/10 ,  A61P9/04

CPC classification number: C07D471/04 ,  A61K31/437

Abstract: The present invention relates to compounds of formula (I), and their pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or N-oxides, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases and immune disorders.

Abstract translation: 本发明涉及作为SSAO活性抑制剂的式（I）化合物及其药学上可接受的盐，溶剂合物，水合物，几何异构体，互变异构体，旋光异构体或N-氧化物。 本发明进一步涉及包含这些化合物的药物组合物以及这些化合物用于治疗其中SSAO活性抑制是有益的医学病症如炎性疾病和免疫疾病的用途。

公开(公告)号：US20080262214A1

公开(公告)日：2008-10-23

申请号：US10581544

申请日：2004-12-03

Applicant: Edward Daniel Savory

Inventor： Edward Daniel Savory

IPC: C07H19/167

CPC classification number: C07H19/167 ,  Y02P20/55

Abstract: A method of synthesis of a 2-substituted adenosine of formula I which comprises converting a compound of formula II to a compound of formula (I), wherein: R is C 1-6 alkoxy (straight or branched), a phenoxy group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3-, cyano, nitro, C 1-6 alkyl, or C 1-6 alkoxy), a benzoyl group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3-, cyano, nitro, C1_6 alkyl, or C1_6 alkoxy), or a benzoyl group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3-, cyano, nitro, C 1-6 alkyl, or C 1-6 alkoxy); R′═H, or a protecting group.

Abstract translation: 一种合成式I的2-取代腺苷的方法，其包括将式II化合物转化为式（I）化合物，其中：R是C 1-6烷氧基（直链或支链），苯氧基（未取代的 ，或被卤素，氨基，CF 3 - ，氰基，硝基，C 1-6烷基或C 1-6烷氧基单取代，或被二取代的苯甲酰基， 卤素，氨基，CF 3 - ，氰基，硝基，C 1-6烷基或C 1-6烷氧基）或苯甲酰基（未取代的，或被卤素，氨基，CF 3 - ，氰基，硝基，C 1-6 烷基或C 1-6烷氧基）; R'-H，或保护基。

公开(公告)号：US20070084329A1

公开(公告)日：2007-04-19

申请号：US11638883

申请日：2006-12-13

Applicant: John Allen ,  John Bacino ,  Chao Chu ,  Edward Daniel ,  Dean Gambale ,  Alex Hobson ,  Paul Zuk

Inventor： John Allen ,  John Bacino ,  Chao Chu ,  Edward Daniel ,  Dean Gambale ,  Alex Hobson ,  Paul Zuk

IPC: G10D1/00 ,  B27N5/00

CPC classification number: G10D3/10

Abstract: Novel musical instrument strings and methods for making the same. Polymer cover combined with a low temperature resin is provided to the strings. Also disclosed are novel plastic materials comprising a film of porous fluoropolymer having UV-cured resin applied to at least a portion of the porosity of the film.

公开(公告)号：US5882245A

公开(公告)日：1999-03-16

申请号：US848921

申请日：1997-05-01

Applicant: Dragan Popovich ,  John Lang Lombardi ,  Edward Daniel Albrecht ,  Anthony Christopher Mulligan ,  Gregory John Artz

Inventor： Dragan Popovich ,  John Lang Lombardi ,  Edward Daniel Albrecht ,  Anthony Christopher Mulligan ,  Gregory John Artz

IPC: B24B37/00 ,  B24B37/27 ,  B24B37/28 ,  B29K61/00 ,  B29K63/00 ,  H01L21/304 ,  H01L21/68 ,  H01L21/683 ,  B24B7/22

CPC classification number: B24B37/28

Abstract: A carrier is comprised of a thermoplastic polymer such as polyetheretherketone which is formed or fabricated as a uniform thickness, double sided flat sheet of material with wafer passages therethrough and gear teeth formed or fabricated around the peripheral edge thereof so as to be cooperative with a wafer polishing machine. An extrusion or rolling or calendering process provides a flat carrier which is, optionally, coated with thermoset polymer or thermoplastic film.

Abstract translation: 载体由诸如聚醚醚酮的热塑性聚合物组成，其形成或制造为具有均匀厚度的双面平板材料，具有通过其的晶片通道，以及围绕其周边边缘形成或制造的齿轮齿，以便与晶片 抛光机。 挤出或轧制或压延方法提供了平坦的载体，其可任选地涂覆有热固性聚合物或热塑性膜。

公开(公告)号：US5753180A

公开(公告)日：1998-05-19

申请号：US695354

申请日：1996-08-09

Applicant: Edward Daniel Burger

Inventor： Edward Daniel Burger

IPC: A01N35/06 ,  C23F11/12 ,  E21B41/02 ,  E21B43/20 ,  C23F11/00 ,  C23F11/06

CPC classification number: E21B43/20 ,  A01N35/06 ,  C23F11/122 ,  E21B41/02

Abstract: A non-biocidal method for inhibiting microbially influenced corrosion of susceptible metal surfaces having an anaerobic biofilm containing active sulfate-reducing bacteria comprising contacting the biofilm with a liquid dispersion of anthraquinone compound.

Abstract translation: 一种用于抑制具有含有活性硫酸盐还原细菌的厌氧生物膜的敏感金属表面的微生物影响的腐蚀的非杀生物方法，包括使生物膜与蒽醌化合物的液体分散体接触。

公开(公告)号：US5708066A

公开(公告)日：1998-01-13

申请号：US396998

申请日：1995-03-01

Applicant: Edward Daniel Otremba ,  Raymond Mitchell Friscia ,  Edward Francis McBride

Inventor： Edward Daniel Otremba ,  Raymond Mitchell Friscia ,  Edward Francis McBride

IPC: C04B24/04 ,  C04B26/06 ,  C04B111/54 ,  C08F2/44 ,  C08F220/12 ,  C08F230/02 ,  C08F265/06 ,  C08F299/00 ,  C08K3/00 ,  C08K3/22 ,  C08K5/524 ,  C08L33/12 ,  C08L43/02 ,  C08L101/00 ,  C08J5/10 ,  C08K5/52 ,  C08L33/10

CPC classification number: C04B26/06 ,  C08K3/22 ,  C08K5/524

Abstract: Acrylic compositions filled with alumina trihydrate with the mixed ester reaction product of propylene glycol methacrylate and phosphorus pentoxide have superior mechanical properties and ease of manufacture. In such acrylic compositions, the ester reaction product imparts superior properties by acting as a very effective coupling agent between the alumina trihydrate filler and the acrylic matrix.

Abstract translation: 填充有三水合氧化铝的丙烯酸组合物与丙二醇甲基丙烯酸酯和五氧化二磷的混合酯反应产物具有优异的机械性能和易于制造。 在这种丙烯酸组合物中，酯反应产物通过在三水合氧化铝填料和丙烯酸基体之间作为非常有效的偶联剂赋予了优异的性能。

公开(公告)号：US1089199A

公开(公告)日：1914-03-03

申请号：US1913769197

申请日：1913-05-22

Applicant: FITZPATRICK EDWARD DANIEL

Inventor： FITZPATRICK EDWARD DANIEL

CPC classification number: F24B15/005 ,  A24F29/00 ,  G04B47/006

公开(公告)号：US990274A

公开(公告)日：1911-04-25

申请号：US1910552106

申请日：1910-03-28

Applicant: KNAPP EDGAR JONAS ,  MCLAUGHLIN EDWARD DANIEL

Inventor： KNAPP EDGAR JONAS ,  MCLAUGHLIN EDWARD DANIEL

CPC classification number: H01M4/70

公开(公告)号：US651467A

公开(公告)日：1900-06-12

申请号：US1899731641

申请日：1899-09-25

Applicant: MEIER EDWARD DANIEL

Inventor： MEIER EDWARD DANIEL

CPC classification number: F23M5/02

公开(公告)号：US09353086B2

公开(公告)日：2016-05-31

申请号：US13878968

申请日：2011-10-13

Applicant: Edward Daniel Savory ,  Alison Stewart ,  Allison Carley ,  Giles Brown ,  Iain Simpson ,  Kathryn Oliver ,  Lee Patient ,  Michael Higginbottom ,  Andrew Graham Cole

Inventor： Edward Daniel Savory ,  Alison Stewart ,  Allison Carley ,  Giles Brown ,  Iain Simpson ,  Kathryn Oliver ,  Lee Patient ,  Michael Higginbottom ,  Andrew Graham Cole

IPC: A61K31/55 ,  A61K31/551 ,  A61K31/439 ,  C07D401/14 ,  C07D405/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D471/08 ,  C07D471/12 ,  A61K45/06 ,  C07D401/12

CPC classification number: C07D471/08 ,  A61K45/06 ,  C07B59/002 ,  C07B2200/05 ,  C07D401/04 ,  C07D401/12 ,  C07D401/14 ,  C07D405/14 ,  C07D413/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04

Abstract: Disclosed are compounds that are antagonists of the CXCR4 receptor.

Abstract translation: 公开了作为CXCR4受体的拮抗剂的化合物。