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公开(公告)号：USD626287S1
公开(公告)日：2010-10-26
申请号：US29344114
申请日：2009-09-23
申请人： Eric M. Simon , Randall D. Block
设计人： Eric M. Simon , Randall D. Block
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公开(公告)号：US20100055790A1
公开(公告)日：2010-03-04
申请号：US12514798
申请日：2007-11-14
申请人： Eric M. Simon
发明人： Eric M. Simon
摘要： A cell culture apparatus consists of a vessel or array of vessels, each comprising a substantially flat bottom and substantially vertical sides, and composed of a substantially gas permeable material. The inner bottom surface of the vessel is commonly textured to provide the cells with adequate features for attachment and spreading. The vessel may include an integral annular flange which can be used to suspend the vessel from a suspensory element of a rack structure. To promote cell attachment and growth, the inner surfaces of the vessel bottom and sides may be coated with commonly available bio-active materials. Cells cultured in the system commonly grow in three dimensions for extended periods of time, and often produce significantly higher quantities of cellular products than cells grown in conventional labware.
摘要翻译： 细胞培养装置由容器或容器阵列组成，每个容器包括基本上平坦的底部和基本上垂直的侧面，并且由基本上透气的材料构成。 容器的内底表面通常是纹理化的，为细胞提供足够的附着和扩散特征。 容器可以包括整体的环形凸缘，其可以用于将容器悬挂在齿条结构的悬挂元件上。 为了促进细胞附着和生长，容器底部和侧面的内表面可以涂覆有常用的生物活性材料。 在系统中培养的细胞通常在三维中长时间生长，并且通常比常规实验器皿中生长的细胞产生显着更高量的细胞产物。
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公开(公告)号：US07275888B1
公开(公告)日：2007-10-02
申请号：US11333887
申请日：2006-01-18
CPC分类号： E01F13/02 , E01F13/022 , E01F15/083 , E01F15/086 , E01F15/088
摘要： A stackable interlocking barrier system includes a first barrier having a front wall and a back wall each extending between a top wall and a floor, at least a portion of the front wall being sloped relative to the back wall. A second barrier also has a front wall and a back wall each extending between a top wall and a floor, at least a portion of the front wall being sloped relative to the back wall. The second barrier is inverted relative to the first barrier with the front wall of the second barrier seated against the front wall of the first barrier. A first connector is removably mounted on the first barrier and the second barrier so as to secure the first barrier to the second barrier.
摘要翻译： 一种可堆叠互锁屏障系统包括：第一屏障，其具有前壁和后壁，每个壁在顶壁和地板之间延伸，前壁的至少一部分相对于后壁倾斜。 第二屏障还具有前壁和后壁，其分别在顶壁和地板之间延伸，前壁的至少一部分相对于后壁倾斜。 第二屏障相对于第一屏障反转，第二屏障的前壁抵靠第一屏障的前壁。 第一连接器可移除地安装在第一屏障和第二屏障上，以便将第一屏障固定到第二屏障。
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公开(公告)号：USRE39772E1
公开(公告)日：2007-08-14
申请号：US10225687
申请日：1997-03-19
申请人： James N. Herron , Douglas A. Christensen , Victor A. Pollack , Richard D. McEachern , Eric M. Simon
发明人： James N. Herron , Douglas A. Christensen , Victor A. Pollack , Richard D. McEachern , Eric M. Simon
IPC分类号： G02B6/26 , G02B6/10 , G01N21/00 , G01N33/552 , G01N33/72
CPC分类号： G01N21/0303 , G01N2021/058
摘要： Improvements in a biosensor of the type having reservoirs or wells for analyzing a biological liquid are disclosed. A biosensor (190) includes a waveguide (164) placed between a plurality of members such as plates (100, 186), at least one of the members (100) being formed to define the walls (132, 134, 136) of the reservoirs where the liquid is biologically analyzed. The walls of the reservoirs are made of an inert, opaque material such as a metal. Although the biosensor may include a gasket (162), the gasket is associated with the members and waveguide in such a way (e.g. by recessing the gasket into a channel formed into a metal plate) so that the gasket does not form any significant portion of the reservoir wall. Waveguides of varying composition (e.g. plastic, quartz or glass) may be associated with the members to form the biosensor. The metal plate of the biosensor has input and output ports for infusing, draining, or oscillating the liquid to be analyzed in the reaction reservoir. Also disclosed is a sled-shaped waveguide associated with a rear lens to couple light out of the waveguide to serve as a quality control measure thus insuring that the biosensor is properly placed and that the light is working.
摘要翻译： 公开了具有用于分析生物液体的储存器或孔的类型的生物传感器的改进。 生物传感器（190）包括布置在诸如板（100,186）之间的多个构件之间的波导（164），所述构件（100）中的至少一个被形成以限定所述壁（132,134,136） 生物分析液体的储层。 储存器的壁由惰性的不透明材料如金属制成。 虽然生物传感器可以包括垫圈（162），但是垫圈以这样的方式（例如通过将垫圈凹入形成金属板的通道）与构件和波导相关联，使得垫圈不形成任何重要的部分 水库墙。 不同组成的波导（例如塑料，石英或玻璃）可以与成员相关联以形成生物传感器。 生物传感器的金属板具有输入和输出端口，用于在反应槽中输入，排出或振荡待分析液体。 还公开了一种与后透镜相关联的雪橇形波导，以将光从波导耦合以用作质量控制措施，从而确保生物传感器被正确放置并且光正在工作。
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公开(公告)号：US06356676B1
公开(公告)日：2002-03-12
申请号：US09608714
申请日：2000-06-30
申请人： James N. Herron , Douglas A. Christensen , Victor A. Pollak , Richard D. McEachern , Eric M. Simon
发明人： James N. Herron , Douglas A. Christensen , Victor A. Pollak , Richard D. McEachern , Eric M. Simon
IPC分类号： G02B626
CPC分类号： G01N21/0303 , G01N21/05 , G01N2021/0346
摘要： Improvements in a biosensor of the type having reservoirs or wells for analyzing a biological liquid are disclosed. A biosensor includes a waveguide placed between a plurality of members such as plates at least one of the members being formed to define the walls of the reservoirs where the liquid is biologically analyzed. The walls of the reservoirs are made of an inert, opaque material such as a metal. Although the biosensor may include a gasket, the gasket is associated with the members and waveguide in such a way (e.g., by recessing the gasket into a channel formed into a metal plate) so that the gasket does not form any significant portion of the reservoir wall. Waveguides of varying composition (e.g., plastic, quartz or glass) may be associated with the members to form the biosensor. The metal plate of the biosensor has input and output ports for infusing, draining, or oscillating the liquid to be analyzed in the reaction reservoir. Also disclosed is a sled-shaped waveguide associated with a rear lens to couple light out of the waveguide to serve as a quality control measure thus insuring that the biosensor is properly placed and that the light is working.
摘要翻译： 公开了具有用于分析生物液体的储存器或孔的类型的生物传感器的改进。 生物传感器包括放置在诸如板之间的多个构件之间的波导，所述构件中的至少一个形成为限定储存器的壁，其中液体被生物分析。 储存器的壁由惰性的不透明材料如金属制成。 虽然生物传感器可以包括垫圈，但是垫圈以这样的方式（例如通过将垫圈凹入形成金属板的通道）与构件和波导相关联，使得垫圈不形成储存器的任何重要部分 壁。 不同组成的波导（例如，塑料，石英或玻璃）可以与成员相关联以形成生物传感器。 生物传感器的金属板具有输入和输出端口，用于在反应槽中输入，排出或振荡待分析液体。 还公开了一种与后透镜相关联的雪橇形波导，以将光从波导耦合以用作质量控制措施，从而确保生物传感器被正确放置并且光正在工作。
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公开(公告)号：USD451196S1
公开(公告)日：2001-11-27
申请号：US29119377
申请日：2000-02-28
申请人： Randall D. Block , Eric M. Simon
设计人： Randall D. Block , Eric M. Simon
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公开(公告)号：US5167625A
公开(公告)日：1992-12-01
申请号：US595087
申请日：1990-10-09
申请人： Stephen C. Jacobsen , Barry K. Hanover , Eric M. Simon , Tomasz Petelenz , Michael G. Mladejovsky
发明人： Stephen C. Jacobsen , Barry K. Hanover , Eric M. Simon , Tomasz Petelenz , Michael G. Mladejovsky
CPC分类号： A61M31/002
摘要： An implantable drug delivery system includes a housing having a plurality of compartments each of which includes an opening on one side thereof and a floor generally opposite the opening. Also included are a plurality of flexible drug containment sacks, each having a mouth circumscribing an opening in the sack, with the sack being disposed in a respective compartment with the mouth affixed to the opening of that compartment to seal the inside of the sack from the inside of the compartment and to enable holding a drug formulation in the sack. A plurality of covers are disposed over a respective compartment opening for preventing the release of drug formulation contained in the sacks in the compartment covered, until ruptured or removed. A plurality of gas generating elements are disposed at the floor of a respective compartment under the sack in that compartment and are responsive to initiation signals for producing gas to force the sacks and drug formulations against the covers to thereby rupture or remove the covers and force the formulations out of the housing. An electrical circuit supplies initiation signals to the gas generating means to initiate production of the gas and thus discharge of the drug formulation.
摘要翻译： 可植入药物输送系统包括具有多个隔室的壳体，每个隔室在其一侧包括一个开口和与开口大致相对的底板。 还包括多个柔性药物容纳袋，每个袋具有围绕袋中的开口的口，其中袋被设置在相应的隔室中，口中固定有该隔室的开口以将袋的内部从 在隔间内部，并且能够在药袋中保持药物制剂。 多个盖设置在相应的隔室开口上，用于防止包装在被覆盖的隔室中的袋中的药物制剂的释放，直到破裂或移除。 多个气体发生元件设置在该隔间中的袋下面的相应隔室的底板处，并响应于产生气体的起始信号，以迫使袋和药物制剂抵靠盖，从而破裂或移除盖并迫使 制剂出了房屋。 电路将起始信号提供给气体发生装置以启动气体的产生，从而释放药物制剂。
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公开(公告)号：US08475510B2
公开(公告)日：2013-07-02
申请号：US12565616
申请日：2009-09-23
申请人： Eric M. Simon , Randall D. Block
发明人： Eric M. Simon , Randall D. Block
CPC分类号： A01K13/001 , A01K13/002 , A01K13/003 , A45D20/12 , A45D24/30
摘要： Disclosed are embodiments of airflow applicators used for delivering directional, heated air to, for example, the scalp and hair of humans and/or animals to eliminate ectoparasites, such as lice and lice eggs. In preferred embodiments, the applicators are configured to deliver heated airflow (from a separate device, or from another portion of a single device, that generates heated airflow) efficiently right to where ectoparasites and their eggs most frequently reside. Also disclosed are treatment methods, including preferred treatment patterns, for delivering heated airflows for use in eliminating ectoparasites and their eggs on an animal.
摘要翻译： 公开了用于将定向加热的空气递送到人和/或动物的头皮和头发以消除诸如虱子和虱子卵的外寄生物的气流施加器的实施例。 在优选实施例中，施用器被配置成有效地传递加热的气流（来自单独的装置，或者来自单个装置的另一部分，产生加热的气流），直到外寄生虫和它们的卵最常存在的地方。 还公开了用于递送用于在动物上消除体外寄生虫及其卵的热气流的治疗方法，包括优选的处理模式。
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公开(公告)号：US20100071713A1
公开(公告)日：2010-03-25
申请号：US12565616
申请日：2009-09-23
申请人： Eric M. Simon , Randall D. Block
发明人： Eric M. Simon , Randall D. Block
CPC分类号： A01K13/001 , A01K13/002 , A01K13/003 , A45D20/12 , A45D24/30
摘要： Disclosed are embodiments of airflow applicators used for delivering directional, heated air to, for example, the scalp and hair of humans and/or animals to eliminate ectoparasites, such as lice and lice eggs. In preferred embodiments, the applicators are configured to deliver heated airflow (from a separate device, or from another portion of a single device, that generates heated airflow) efficiently right to where ectoparasites and their eggs most frequently reside. Also disclosed are treatment methods, including preferred treatment patterns, for delivering heated airflows for use in eliminating ectoparasites and their eggs on an animal.
摘要翻译： 公开了用于将定向加热的空气递送到人和/或动物的头皮和头发以消除诸如虱子和虱子卵的外寄生物的气流施加器的实施例。 在优选实施例中，施用器被配置成有效地传递加热的气流（来自单独的装置，或来自单个装置的另一部分，产生加热的气流），直到其外部寄生虫和它们的卵最常存在的地方。 还公开了用于递送用于在动物上消除体外寄生虫及其卵的热气流的治疗方法，包括优选的处理模式。
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公开(公告)号：US06611634B2
公开(公告)日：2003-08-26
申请号：US10095540
申请日：2002-03-11
申请人： James N. Herron , Douglas A. Christensen , Victor A. Pollak , Richard D. McEachern , Eric M. Simon
发明人： James N. Herron , Douglas A. Christensen , Victor A. Pollak , Richard D. McEachern , Eric M. Simon
IPC分类号： G02B600
CPC分类号： G01N21/0303 , G01N21/05 , G01N2021/0346 , G01N2021/058
摘要： Improvements in a biosensor are disclosed. A biosensor includes a waveguide, at least a portion of which is substantially planar. One or more reservoirs may be formed adjacent to a chemistry-bearing surface of the waveguide. The biosensor may include a gasket to form a seal between the waveguide and side walls of the reservoir. A sample solution may be introduced into the reservoir or otherwise onto the surface of a waveguide through an input port. Waveguides of varying composition (e.g., plastic, quartz, glass, or other suitable waveguide materials) may be used in the biosensor. Also disclosed is a sled-shaped waveguide, which includes a planar portion and a lens at an end thereof and angled relative thereto for coupling light into the waveguide.
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