-
1.发明授权Identification of the gene causing the mouse scurfy phenotype and its human ortholog 失效鉴定引起小鼠scurfy表型的基因及其人类直向同源物公开(公告)号：US07220579B2
公开(公告)日：2007-05-22
申请号：US10988852
申请日：2004-11-15
Applicant: Mary E Brunkow , Eric W Jeffery , Kathryn A Hjerrild , Fred Ramsdell
Inventor： Mary E Brunkow , Eric W Jeffery , Kathryn A Hjerrild , Fred Ramsdell
CPC classification number: G01N33/54346 , A61K31/70 , A61K38/00 , C07K14/47 , C07K2319/00 , G01N33/587
Abstract: Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system.
Abstract translation: 提供了分离的核酸分子，其编码Fkh和其突变体形式。 还提供了适于表达这种核酸分子的表达载体和含有这种表达载体的宿主细胞。 利用基于本文公开的核酸序列（以及其突变形式）的测定法，可以鉴定调节免疫系统的许多分子。
-
2.发明授权Identification of the gene causing the mouse scurfy phenotype and its human ortholog 失效鉴定引起小鼠scurfy表型的基因及其人类直向同源物公开(公告)号：US06794145B1
公开(公告)日：2004-09-21
申请号：US09697340
申请日：2000-10-24
Applicant: Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
Inventor： Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
IPC: G01N3353
CPC classification number: G01N33/54346 , A61K31/70 , A61K38/00 , C07K14/47 , C07K2319/00 , G01N33/587
Abstract: Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system.
Abstract translation: 提供编码Fkh
的分离的核酸分子以及其突变体形式。 还提供了适于表达这种核酸分子的表达载体和含有这种表达载体的宿主细胞。 利用基于本文公开的核酸序列（以及其突变形式）的测定法，可以鉴定调节免疫系统的许多分子。 -
3.发明授权Identification of the gene causing the mouse scurfy phenotype and its human ortholog 失效鉴定引起小鼠scurfy表型的基因及其人类直向同源物公开(公告)号：US07135612B2
公开(公告)日：2006-11-14
申请号：US10934250
申请日：2004-09-03
Applicant: Mary E Brunkow , Eric W Jeffery , Kathryn A Hjerrild , Fred Ramsdell
Inventor： Mary E Brunkow , Eric W Jeffery , Kathryn A Hjerrild , Fred Ramsdell
CPC classification number: G01N33/54346 , A61K31/70 , A61K38/00 , C07K14/47 , C07K2319/00 , G01N33/587
Abstract: Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system.
Abstract translation: 提供了分离的核酸分子，其编码Fkh和其突变体形式。 还提供了适于表达这种核酸分子的表达载体和含有这种表达载体的宿主细胞。 利用基于本文公开的核酸序列（以及其突变形式）的测定法，可以鉴定调节免疫系统的许多分子。
-
公开(公告)号：US06683171B1
公开(公告)日：2004-01-27
申请号：US09697341
申请日：2000-10-25
Applicant: Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
Inventor： Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
IPC: C07H2102
CPC classification number: G01N33/54346 , A61K31/70 , A61K38/00 , C07K14/47 , C07K2319/00 , G01N33/587
Abstract: Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system.
-
Patent Agency Ranking
5.发明授权Identification of the gene causing the mouse scurfy phenotype and its human ortholog 失效鉴定引起小鼠scurfy表型的基因及其人类直向同源物公开(公告)号：US06667162B1
公开(公告)日：2003-12-23
申请号：US09697377
申请日：2000-10-25
Applicant: Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
Inventor： Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
IPC: C12P2106
CPC classification number: G01N33/54346 , A61K31/70 , A61K38/00 , C07K14/47 , C07K2319/00 , G01N33/587
Abstract: Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system.
Abstract translation: 提供编码Fkh
的分离的核酸分子以及其突变体形式。 还提供了适于表达这种核酸分子的表达载体和含有这种表达载体的宿主细胞。 利用基于本文公开的核酸序列（以及其突变形式）的测定法，可以鉴定调节免疫系统的许多分子。 -
6.发明授权Identification of the gene causing the mouse scurfy phenotype and its human ortholog 失效鉴定引起小鼠scurfy表型的基因及其人类直向同源物公开(公告)号：US06414129B1
公开(公告)日：2002-07-02
申请号：US09372668
申请日：1999-08-11
Applicant: Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
Inventor： Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
IPC: C07H2102
CPC classification number: G01N33/54346 , A61K31/70 , A61K38/00 , C07K14/47 , C07K2319/00 , G01N33/587
Abstract: Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system
Abstract translation: 提供编码Fkhsf的分离的核酸分子，以及其突变体形式。 还提供了适于表达这种核酸分子的表达载体和含有这种表达载体的宿主细胞。 利用基于本文公开的核酸序列（以及其突变形式）的测定法，可以鉴定调节免疫系统的许多分子
-
7.发明申请Identification of the gene causing the mouse scurfy phenotype and its human ortholog 审中-公开鉴定引起小鼠scurfy表型的基因及其人类直向同源物公开(公告)号：US20080131411A1
公开(公告)日：2008-06-05
申请号：US11787665
申请日：2007-04-16
Applicant: Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
Inventor： Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
CPC classification number: G01N33/54346 , A61K31/70 , A61K38/00 , C07K14/47 , C07K2319/00 , G01N33/587
Abstract: Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system.
Abstract translation: 提供了分离的核酸分子，其编码Fkh和其突变体形式。 还提供了适于表达这种核酸分子的表达载体和含有这种表达载体的宿主细胞。 利用基于本文公开的核酸序列（以及其突变形式）的测定法，可以鉴定调节免疫系统的许多分子。
-
公开(公告)号：US06884618B2
公开(公告)日：2005-04-26
申请号：US10115195
申请日：2002-04-02
Applicant: Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
Inventor： Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
IPC: A01K67/027 , A61K38/00 , C07K14/47 , C07K16/18 , C07K19/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12P21/02 , C12P21/08 , C12Q1/68 , C12R1/91 , G01N33/53 , G01N33/532 , G01N33/543 , C12N5/00 , C07H21/02 , C07H21/04 , C12N15/00 , C12N15/63
CPC classification number: G01N33/54346 , A61K31/70 , A61K38/00 , C07K14/47 , C07K2319/00 , G01N33/587
Abstract: Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system.
-
公开(公告)号：US06683160B1
公开(公告)日：2004-01-27
申请号：US09696868
申请日：2000-10-25
Applicant: Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
Inventor： Mary E. Brunkow , Eric W. Jeffery , Kathryn A. Hjerrild , Fred Ramsdell
IPC: C07K1600
CPC classification number: G01N33/54346 , A61K31/70 , A61K38/00 , C07K14/47 , C07K2319/00 , G01N33/587
Abstract: Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Assays that are based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), may be used for identifying numerous molecules that modulate the immune system. Molecules that specifically bind to an Fkhsf polypeptide are also provided as useful, such as, for modulating the biological activities of Fkhsf. In particular, antibodies that are specific for Fkhsf polypeptide are provided for uses such as for detecting the expression of an Fkhsf polypeptide in cells, isolating an Fkhsf polypeptide, and modulating the activity of an Fkhsf polypeptide.
Abstract translation: 提供编码Fkh
的分离的核酸分子以及其突变体形式。 还提供了适于表达这种核酸分子的表达载体和含有这种表达载体的宿主细胞。 基于本文公开的核酸序列（以及其突变形式）的测定可用于鉴定调节免疫系统的许多分子。 特异性结合Fkh 多肽的分子也可用作调节Fkh 的生物学活性的有用物质。 特别地，针对Fkh多肽特异性的抗体被提供用于例如用于检测细胞中Fkh 多肽的表达，分离Fkh 多肽以及调节Fkh 多肽的活性 >多肽。
-
-
-
-
-
-
-
-
Search Results
9
records
(took 0.018 seconds)
