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    METHANOL PRODUCTION PROCESS
    3.
    发明申请
    METHANOL PRODUCTION PROCESS 审中-公开

    公开(公告)号：US20200207689A1

    公开(公告)日：2020-07-02

    申请号：US15998895

    申请日：2017-02-16

    申请人： FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ)

    发明人： Atsushi URAKAWA ,  Atul BANSODE ,  Rohit Vilas GAIKWAD

    IPC分类号： C07C29/154 ,  B01J23/06 ,  B01J23/72 ,  B01J35/02 ,  B01J35/10

    摘要： The invention provides a process for producing methanol, which process comprises contacting H2 and CO2 with a solid catalyst, at a temperature of from 200° C. to 300° C. and at a reactant pressure of from 150 bar to 500 bar, which reactant pressure is the sum of the partial pressures of the H2 and the CO2, wherein: the molar ratio of the H2 to the CO2 is x:1.0, wherein x is from 2.5 to 3.5; and the catalyst comprises: (i) a copper component which is Cu, CuO or Cu2O, or a mixture of two or three thereof, and (ii) ZnO, wherein the catalyst has a specific copper surface area of at least 10 m2/g-catalyst.

    RATIOMETRIC ASSAY FOR HYDROLYTIC ENZYME QUANTIFICATION
    7.
    发明申请
    RATIOMETRIC ASSAY FOR HYDROLYTIC ENZYME QUANTIFICATION 审中-公开
    水解酶的定量测定

    公开(公告)号：US20160139137A1

    公开(公告)日：2016-05-19

    申请号：US14900133

    申请日：2014-06-23

    申请人： FUNDACIÓ INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) ,  INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS

    发明人： Emilio PALOMARES ,  Georgiana STOICA ,  Iván CASTELLÓ SERRANO

    IPC分类号： G01N33/58 ,  C12Q1/37

    CPC分类号： G01N33/588 ,  C09K11/02 ,  C09K11/025 ,  C09K11/883 ,  C12Q1/34 ,  C12Q1/37 ,  G01N2333/914 ,  G01N2333/976 ,  G01N2458/00 ,  G01N2800/382

    摘要： The invention refers to a nanoparticle comprising (i) a core comprising a first population of quantum dots (QDs) embedded in silica, (ii) a shell comprising a second population of QDs embedded in silica, (iii) at least one biomolecule selected from a peptide, a nucleic acid, a carbohydrate or a lipid which comprises a cleavage site that is susceptible of being cleaved by a hydrolytic enzyme, said biomolecule being bound to the surface of the shell through a moiety, and (iv) a photoluminescent label for each biomolecule, wherein the label is bound to the part of the biomolecule which detaches from the nanoparticle after cleavage of said biomolecule by a hydrolytic enzyme, wherein the first and second QD populations have different maximum photoluminescence emission wavelengths, and only the second QD population is susceptible of producing Forster resonance energy transfer (FRET) with the photoluminescent label.

    摘要翻译： 本发明涉及一种纳米颗粒，其包含（i）包含嵌入二氧化硅中的第一批量子点（QD）的核心，（ii）包含埋在二氧化硅中的第二组质子数量的壳体，（iii）至少一种选自以下的生物分子： 肽，核酸，碳水化合物或脂质，其包含易于被水解酶切割的切割位点，所述生物分子通过部分结合到壳的表面，和（iv）光致发光标记，用于 每个生物分子，其中所述标记与所述生物分子的部分结合，所述部分在通过水解酶切割所述生物分子之后与所述纳米颗粒分离，其中所述第一和第二QD群体具有不同的最大光致发光发射波长，并且仅第二QD群体 容易产生与光致发光标签的福斯特共振能量转移（FRET）。