公开(公告)号：US20220074657A1

公开(公告)日：2022-03-10

申请号：US17415688

申请日：2018-12-19

申请人： Eric DAY ,  Fei GAO ,  Huali XIE ,  L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges Claude

发明人： Eric DAY ,  Fei GAO ,  Huali XIE

IPC分类号： F25J3/04

摘要： In a process for starting up an air separation unit, which is at a temperature of above 0° C., the air separation unit comprising a main air compressor for compressing the feed air, a booster driven by a turbine and a venting conduit connected downstream of the booster and upstream of the main heat exchanger wherein in order to start up the air separation unit, once the turbine is operating at said given speed, the venting conduit is opened to send at least part of the air compressed in the booster from the booster outlet to the atmosphere.

公开(公告)号：US20210369416A1

公开(公告)日：2021-12-02

申请号：US16888789

申请日：2020-05-31

申请人： Fei Gao

发明人： Fei Gao

IPC分类号： A61C7/14 ,  A61C7/00 ,  A61C7/28

摘要： A bracket bonding guide, insertion tool and method to place orthodontic brackets to predetermined positions and orientations. Indirect bonding trays typically are made to fit specific brackets of specific shapes and parameters. Design software has to include bracket CAD files in order to work for specific brands. This invention presented a bonding guide with guiding features and insertion tools with alignment mechanism and guiding features that ensure the brackets will be placed onto right positions regardless the actual shape and dimensions of the brackets.

公开(公告)号：US20140256563A1

公开(公告)日：2014-09-11

申请号：US14119266

申请日：2012-05-22

申请人： Huijuan Luo ,  Guanyu Ji ,  Hui Jiang ,  Mingzhi Wu ,  Jihua Sun ,  Renhua Wu ,  Junwen Wang ,  Fei Gao

发明人： Huijuan Luo ,  Guanyu Ji ,  Hui Jiang ,  Mingzhi Wu ,  Jihua Sun ,  Renhua Wu ,  Junwen Wang ,  Fei Gao

IPC分类号： C12Q1/68 ,  C12N15/10

CPC分类号： C12Q1/6874 ,  C12N15/1065 ,  C12Q1/6806 ,  C12Q1/6869 ,  C40B50/06 ,  C12Q2523/125 ,  C12Q2525/191 ,  C12Q2535/122 ,  C12Q2537/159

摘要： Provided is a high throughput methylation detection method, particularly a combined sequence capture and bisulfite sequencing method. The method accurately and effectively analyzes the methylation status of the target area in several samples simultaneously, lowers the difficulty of probe design, enhances operation and application feasibility, and enables high throughput methylation detection of high accuracy on interested target sequences and areas in a complete genome. The method is targeted and conserves energy and time.

摘要翻译： 提供了高通量甲基化检测方法，特别是组合的序列捕获和亚硫酸氢盐测序方法。 该方法同时精确有效地分析了几个样本中目标区域的甲基化状态，降低了探针设计的难度，提高了操作和应用的可行性，并且使得在完整基因组中有兴趣的靶序列和区域具有高准确度的高通量甲基化检测 。 该方法是针对性的，节约能源和时间。

公开(公告)号：US08832019B2

公开(公告)日：2014-09-09

申请号：US13017476

申请日：2011-01-31

申请人： Fei Gao

发明人： Fei Gao

IPC分类号： G06Q50/22 ,  G06F19/00

CPC分类号： G06F19/3437 ,  G06F19/00 ,  G16H50/50 ,  Y10S128/92 ,  Y10S128/922 ,  Y10S128/923 ,  Y10S128/924 ,  Y10S706/919 ,  Y10S706/92 ,  Y10S706/924

摘要： A method and system to evaluate image-guided dental implant treatment plans with error simulation. Error sources contributing to the inaccuracy of implant cases come from impressions, stone models, radiographic guides, CT scan and its image processing, surgical guides, as well as the surgical procedures. They are translated into the deviations between the planned and actual implant positions and orientations. The error simulation is to continuously modify and update treatment plans with the possible deviations so that the treatment plans can be visually evaluated along with other evaluation tools.

摘要翻译： 用错误模拟评估图像引导牙种植体治疗计划的方法和系统。 导致种植体病例不准确的错误来源来自印象，石头模型，放射学指南，CT扫描及其图像处理，手术指南以及外科手术。 它们被转化为计划的和实际的植入物位置和取向之间的偏差。 错误模拟是不断修改和更新治疗计划，并将其与可能的偏差进行比较，以便与其他评估工具一起进行肉眼评估。

公开(公告)号：US08371849B2

公开(公告)日：2013-02-12

申请号：US12911895

申请日：2010-10-26

申请人： Fei Gao

发明人： Fei Gao

IPC分类号： G06G7/60

CPC分类号： A61C13/0004 ,  A61C1/084 ,  A61C13/01 ,  B33Y50/00 ,  B33Y80/00

摘要： A method and a dental implant treatment planning and surgical guide design system based on a full anatomy model (FAM). A FAM consists of models for bones, teeth, and nerves, and a virtual stone model. A virtual stone model is not only a surface model of the soft tissue and tooth surfaces of a patient, but also a color map of tissue thickness data. It also contains the insert direction of a surgical guide. The treatment planning and surgical guide system uses the full anatomy model as a unique reference throughout the workflow. Its implant placement, restoration preview and surgical guide design are all based on the anatomy model.

摘要翻译： 一种基于完全解剖模型（FAM）的方法和牙种植体治疗计划和手术指南设计系统。 FAM包括骨骼，牙齿和神经的模型，以及虚拟石头模型。 虚拟石模型不仅是患者的软组织和牙齿表面的表面模型，而且是组织厚度数据的颜色图。 它还包含手术导管的插入方向。 治疗计划和手术指南系统使用完整的解剖模型作为整个工作流程中的独特参考。 其植入位置，修复预览和手术指南设计均基于解剖模型。

公开(公告)号：US20120276653A1

公开(公告)日：2012-11-01

申请号：US13389433

申请日：2010-08-13

申请人： Christopher Tarpey ,  Mary Catherine Parsons ,  Lijian Gou ,  Haipeng Hu ,  Fei Gao ,  Yinfei Wu

发明人： Christopher Tarpey ,  Mary Catherine Parsons ,  Lijian Gou ,  Haipeng Hu ,  Fei Gao ,  Yinfei Wu

IPC分类号： G01N21/75

CPC分类号： G01N1/10 ,  G01N33/4875 ,  G01N33/493 ,  G01N2001/022 ,  G01N2001/027

摘要： A detection device (100) comprises a detecting chamber (32) containing a detecting element for analyzing whether a specimen containing an analyte, and an indicating element (8) displaying whether the detection is activated. The method for using the detection device (100) is also disclosed.

摘要翻译： 检测装置（100）包括检测室（32），其包含用于分析含有分析物的样本的检测元件和显示检测是否被激活的指示元件（8）。 还公开了使用检测装置（100）的方法。

公开(公告)号：US20120237923A1

公开(公告)日：2012-09-20

申请号：US13481599

申请日：2012-05-25

申请人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

发明人： Huiyan Guo ,  Min Wang ,  Tao Shang ,  Hui-Kang Chen ,  Fei Gao

IPC分类号： G01N21/78 ,  C12Q1/04 ,  G01N33/566 ,  C12Q1/70

CPC分类号： G01N33/521 ,  Y10S436/808 ,  Y10S436/81

摘要： Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invention provides an improved procedural control that indicates to the test user that at least a portion of the applied sample has passed through the test result zone of the test strip, and optionally that the test is complete and the test results may be read.

摘要翻译： 快速侧流免疫测定在临床和家庭环境中具有广泛的应用历史。 这些装置用于测试各种分析物，例如滥用药物，激素，蛋白质，尿液或血浆成分等。 本发明提供了一种改进的程序控制，其向测试用户指示所应用样品的至少一部分已经通过测试条的测试结果区域，并且可选地，测试完成并且可以读取测试结果。

公开(公告)号：US20120197620A1

公开(公告)日：2012-08-02

申请号：US13017476

申请日：2011-01-31

申请人： Fei Gao

发明人： Fei Gao

IPC分类号： G06G7/60

CPC分类号： G06F19/3437 ,  G06F19/00 ,  G16H50/50 ,  Y10S128/92 ,  Y10S128/922 ,  Y10S128/923 ,  Y10S128/924 ,  Y10S706/919 ,  Y10S706/92 ,  Y10S706/924

摘要： A method and system to evaluate image-guided dental implant treatment plans with error simulation. Error sources contributing to the inaccuracy of implant cases come from impressions, stone models, radiographic guides, CT scan and its image processing, surgical guides, as well as the surgical procedures. They are translated into the deviations between the planned and actual implant positions and orientations. The error simulation is to continuously modify and update treatment plans with the possible deviations so that the treatment plans can be visually evaluated along with other evaluation tools.

摘要翻译： 用错误模拟评估图像引导牙种植体治疗计划的方法和系统。 导致种植体病例不准确的错误来源来自印象，石头模型，放射学指南，CT扫描及其图像处理，手术指南以及外科手术。 它们被转化为计划的和实际的植入物位置和取向之间的偏差。 错误模拟是不断修改和更新治疗计划，并将其与可能的偏差进行比较，以便与其他评估工具一起进行肉眼评估。

公开(公告)号：US20120046914A1

公开(公告)日：2012-02-23

申请号：US12860019

申请日：2010-08-20

申请人： Fei Gao

发明人： Fei Gao

IPC分类号： G06F17/50 ,  A61C19/04

CPC分类号： A61C8/0089 ,  A61C1/084 ,  B33Y80/00

摘要： A hybrid method for dental implant treatment planning and a corresponding approach to make a surgical guide. After digital treatment planning is performed with CT scan data, a master model is created, which embodies the patient anatomy and entire treatment plan. Jaw bone, tooth surfaces, soft tissues and nerves are all contained by the master model. The plan details including implant sizes and positions, surgical guide drill options, as well as the choice of a surgical kit, are all conveyed by the master model. Meanwhile, models of specially designed “implant inserts (or replicas)” are also generated, which have one end that fits into the implant holes on the master model and another end to make the surgical guide. The master model and inserts are manufactured with rapid prototyping technology. A surgical guide is later on made from them with conventional lab processes. A main characteristic of this approach is that the master model and the inserts are the physical embodiment of a virtual treatment plan. With them, the surgeons can continue the treatment planning for operations like tooth extractions and bone modifications before making the surgical guides. Therefore the treatment planning workflow is a combination of digital treatment planning and a physical model based planning, in other words, a hybrid approach. A differentiator in this invention is the generation of a closed solid model of the soft tissue, as part of the master model, from the scan data. This approach can be applied to create both bone-borne and tissue-borne surgical guides with low cost process, which is a big advantage over other approaches.

摘要翻译： 牙科植入治疗计划的混合方法和相应的手术指南的方法。 在用CT扫描数据进行数字处理计划后，创建了一个主模型，体现了患者解剖和整个治疗计划。 颌骨，牙齿表面，软组织和神经都由主模型包含。 包括种植体大小和位置的计划细节，手术导引钻孔选项以及手术套件的选择都由主模型传送。 同时，还产生了特殊设计的“植入物插入物（或复制品）”的模型，其具有适合于主模型上的植入孔的一端，另一端形成外科手术导管。 主模型和刀片采用快速原型技术制造。 手术指南随后用传统的实验室工艺制成。 这种方法的主要特征是主模型和插入是虚拟处理计划的物理实施方案。 与他们一起，外科医生可以在制作手术指南之前继续进行诸如拔牙和骨修改等操作的治疗计划。 因此，治疗计划工作流程是数字处理计划和基于物理模型的计划的组合，换句话说，是混合方法。 本发明的微分器是从扫描数据生成作为主模型的一部分的软组织的封闭实体模型。 这种方法可以应用于以低成本过程创建骨传导和组织传导的外科手术导管，这是其他方法的一大优点。

公开(公告)号：US08086410B1

公开(公告)日：2011-12-27

申请号：US12117911

申请日：2008-05-09

申请人： Changsheng Liu ,  Fei Gao

发明人： Changsheng Liu ,  Fei Gao

IPC分类号： G06F19/00 ,  C12Q1/68

CPC分类号： G06F19/18 ,  G06F19/22

摘要： A method for detecting DNA variation. First, by aligning trace data of a sample DNA sequence to trace data of a reference DNA sequence to produce an aligned sample DNA sequence. Then, inputting the trace data of the bases of both the reference DNA sequence and the aligned sample DNA sequence for a particular frame number into a non-linear mathematical function of an anti-correlation calculation scheme for all the frame numbers. Minimal values will be produced at the particular frame number for DNA base trace data of the aligned sample DNA sequence which are not a variation as compared to the reference DNA sequence. Values above the minimal values will be produced at the particular frame number for DNA base trace data of the aligned sample DNA sequence which are a variation as compared to the reference DNA sequence.

摘要翻译： 检测DNA变异的方法。 首先，通过将样本DNA序列的痕量数据对齐到追踪参考DNA序列的数据以产生排列的样品DNA序列。 然后，将用于特定帧号的参考DNA序列和对准样品DNA序列的碱基的痕迹数据输入到所有帧号的反相关计算方案的非线性数学函数中。 与对照样品DNA序列的DNA碱基痕量数据的特定帧编号产生最小值，与参考DNA序列相比不是变异。 高于最小值的值将在对准的样品DNA序列的DNA碱基痕量数据的特定帧数产生，这是与参考DNA序列相比的变体。