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Patent Agency Ranking
![2-[2--1H-Pyrrolo[2,3-D]Pyrimidin-4-YL)Amino] Benzamide Derivatives As IGF-1R Inhibitors For The Treatment Of Cancer](/abs-image/US/2010/08/12/US20100204196A1/abs.jpg.150x150.jpg)
1.发明申请2-[2--1H-Pyrrolo[2,3-D]Pyrimidin-4-YL)Amino] Benzamide Derivatives As IGF-1R Inhibitors For The Treatment Of Cancer 有权2- [2- [1H-吡咯并[2,3-D]嘧啶-4-基）氨基]苯甲酰胺衍生物作为IGF-1R抑制剂治疗癌症公开(公告)号：US20100204196A1
公开(公告)日：2010-08-12
申请号：US12671960
申请日：2008-08-06
Applicant: Stanley Dawes Chamberlain , Felix Deanda, JR. , Roseanne Gerding , Masaichi Hasegawa , Kevin Kuntz , Huangshu Lei , Yasushi Miyazaki , Naohiko Nishigaki , Samarjit Patnaik , Aniko Redman , John Brad Shotwell , Kirk Stevens , Joseph Wilson , Bin Yang
Inventor： Stanley Dawes Chamberlain , Felix Deanda, JR. , Roseanne Gerding , Masaichi Hasegawa , Kevin Kuntz , Huangshu Lei , Yasushi Miyazaki , Naohiko Nishigaki , Samarjit Patnaik , Aniko Redman , John Brad Shotwell , Kirk Stevens , Joseph Wilson , Bin Yang
IPC: A61K31/397 , C07D487/04 , A61K31/519 , A61K31/496 , A61K31/5377 , A61K31/551 , A61P35/00
CPC classification number: C07D487/04 , C07D487/14
Abstract: Novel pyrrolopyrimidines as shown in formula (I): and pharmaceutically acceptable derivatives thereof. The compounds are useful in the inhibition of IGF-1R.
Abstract translation: 式（I）所示的新型吡咯并嘧啶及其药学上可接受的衍生物。 该化合物可用于抑制IGF-1R。
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![2-[2-{phenylamino}-1H-pyrrolo[2,3-D]pyrimidin-4-yl)amino] benzamide derivatives as IGF-1R inhibitors for the treatment of cancer](/abs-image/US/2011/07/19/US07981903B2/abs.jpg.150x150.jpg)
2.发明授权2-[2-{phenylamino}-1H-pyrrolo[2,3-D]pyrimidin-4-yl)amino] benzamide derivatives as IGF-1R inhibitors for the treatment of cancer 有权2- [2- {苯基氨基} -1H-吡咯并[2,3-D]嘧啶-4-基）氨基]苯甲酰胺衍生物作为治疗癌症的IGF-1R抑制剂公开(公告)号：US07981903B2
公开(公告)日：2011-07-19
申请号：US12671960
申请日：2008-08-06
Applicant: Stanley Dawes Chamberlain , Felix Deanda, Jr. , Roseanne Gerding , Masaichi Hasegawa , Kevin Kuntz , Huangshu Lei , Yasushi Miyazaki , Naohiko Nishigaki , Samarjit Patnaik , Aniko Redman , John Brad Shotwell , Kirk Stevens , Joseph Wilson , Bin Yang
Inventor： Stanley Dawes Chamberlain , Felix Deanda, Jr. , Roseanne Gerding , Masaichi Hasegawa , Kevin Kuntz , Huangshu Lei , Yasushi Miyazaki , Naohiko Nishigaki , Samarjit Patnaik , Aniko Redman , John Brad Shotwell , Kirk Stevens , Joseph Wilson , Bin Yang
IPC: A01N43/90 , A61K31/519 , C07D487/00
CPC classification number: C07D487/04 , C07D487/14
Abstract: Novel pyrrolopyrimidines as shown in formula (I): and pharmaceutically acceptable derivatives thereof. The compounds are useful in the inhibition of IGF-1R.
Abstract translation: 式（I）所示的新型吡咯并嘧啶及其药学上可接受的衍生物。 该化合物可用于抑制IGF-1R。
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公开(公告)号：US20100113445A1
公开(公告)日：2010-05-06
申请号：US12531760
申请日：2008-03-12
Applicant: Felix Deanda, JR. , David Harold Drewry , Paul Reid
Inventor： Felix Deanda, JR. , David Harold Drewry , Paul Reid
IPC: A61K31/5377 , C07D403/04 , C07D239/49 , C07D239/48 , C07D413/14 , C07D403/14 , A61K31/505 , A61K31/496 , A61P35/00
CPC classification number: C07D403/04 , C07D239/48 , C07D401/04 , C07D403/14 , C07D405/04 , C07D409/04 , C07D413/14 , C07D417/14 , C07D471/04
Abstract: The present invention relates to dianilinopyrimidine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such dianilinopyrimidine derivatives are useful in the treatment of diseases associated with inappropriate Wee1 kinase activity.
Abstract translation: 本发明涉及二苯胺基嘧啶衍生物，含有它们的组合物和药物，以及这些化合物，组合物和药物的制备和使用方法。 这种二苯胺基嘧啶衍生物可用于治疗与不适当的Wee1激酶活性相关的疾病。
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公开(公告)号：US20100105674A1
公开(公告)日：2010-04-29
申请号：US12531763
申请日：2008-03-12
Applicant: Felix Deanda Jr. , David Harold Drewry , James Andrew Linn , Paul Reid
Inventor： Felix Deanda Jr. , David Harold Drewry , James Andrew Linn , Paul Reid
IPC: A61K31/5377 , A61K31/506 , C07D413/14 , C07D413/12 , C07D403/04 , C07D239/48 , C07D403/12 , A61P35/00 , C07D401/12 , A61K31/505
CPC classification number: C07D239/42 , A61K31/505 , C07D239/48 , C07D401/04 , C07D403/12
Abstract: The present invention relates to dianilinopyrimidine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such dianilinopyrimidine derivatives are useful in the treatment of diseases associated with inappropriate Wee1 kinase activity.
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公开(公告)号：US07645771B2
公开(公告)日：2010-01-12
申请号：US10538144
申请日：2003-12-12
Applicant: Wieslaw Mieczyslaw Kazmierski , Chrisopher Joseph Aquino , Neil Bifulco , Eric Eugene Boros , Brian Andrew Chauder , Pek Yoke Chong , Maosheng Duan , Felix Deanda, Jr. , Cecilia Suarez Koble , Ed Williams McLean , Jennifer Poole Peckham , Angilique C Perkins , James Benjamin Thompson , Dana Vanderwall
Inventor： Wieslaw Mieczyslaw Kazmierski , Chrisopher Joseph Aquino , Neil Bifulco , Eric Eugene Boros , Brian Andrew Chauder , Pek Yoke Chong , Maosheng Duan , Felix Deanda, Jr. , Cecilia Suarez Koble , Ed Williams McLean , Jennifer Poole Peckham , Angilique C Perkins , James Benjamin Thompson , Dana Vanderwall
IPC: A61K31/46
CPC classification number: C07D451/04
Abstract: The present invention relates to compounds of formula (I) or a pharmaceutically acceptable derivatives thereof, useful in the treatment of prophylazis of CCR5-related diseases and disorders, for example, in the inhibition of HIV replication, the prevention or treatment of HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS).
Abstract translation: 本发明涉及式（I）化合物或其药学上可接受的衍生物，其可用于治疗CCR5相关疾病和病症的预防，例如抑制HIV复制，预防或治疗HIV感染， 以及治疗所得的获得性免疫缺陷综合征（AIDS）。
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