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公开(公告)号：US10945854B2
公开(公告)日：2021-03-16
申请号：US14078614
申请日：2013-11-13
IPC分类号： A61F2/44 , A61L27/46 , C08J9/28 , C08J9/36 , A61F2/28 , C08J9/00 , A61L27/56 , A61L27/12 , A61L27/18 , A61L27/26 , A61L27/54 , B29C67/20 , A61F2/30
摘要： Synthetic composite materials for use, for example, as orthopedic implants are described herein. In one example, a composite material for use as a scaffold includes a thermoplastic polymer forming a porous matrix that has continuous porosity and a plurality of pores. The porosity and the size of the pores are selectively formed during synthesis of the composite material. The example composite material also includes a plurality of a anisometric calcium phosphate particles integrally formed, embedded in, or exposed on a surface of the porous matrix. The calcium phosphate particles provide one or more of reinforcement, bioactivity, or bioresorption.
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公开(公告)号：US20210015977A9
公开(公告)日：2021-01-21
申请号：US14078614
申请日：2013-11-13
摘要： Synthetic composite materials for use, for example, as orthopedic implants are described herein. In one example, a composite material for use as a scaffold includes a thermoplastic polymer forming a porous matrix that has continuous porosity and a plurality of pores. The porosity and the size of the pores are selectively formed during synthesis of the composite material. The example composite material also includes a plurality of a anisometric calcium phosphate particles integrally formed, embedded in, or exposed on a surface of the porous matrix. The calcium phosphate particles provide one or more of reinforcement, bioactivity, or bioresorption.
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公开(公告)号：US20140236299A1
公开(公告)日：2014-08-21
申请号：US14078614
申请日：2013-11-13
CPC分类号： A61F2/4455 , A61F2/28 , A61F2/30965 , A61F2/4465 , A61F2002/2817 , A61F2002/2835 , A61F2002/30006 , A61F2002/30011 , A61F2002/30034 , A61F2002/30062 , A61F2002/30065 , A61F2002/30225 , A61F2002/30235 , A61F2002/30622 , A61F2002/30904 , A61F2002/3092 , A61F2002/30957 , A61F2210/0004 , A61F2210/0071 , A61F2230/0069 , A61F2250/0015 , A61F2250/0018 , A61F2250/0023 , A61F2250/0031 , A61L27/12 , A61L27/18 , A61L27/26 , A61L27/46 , A61L27/54 , A61L27/56 , B29C67/202 , C08J9/0066 , C08J9/28 , C08J9/36
摘要： Synthetic composite materials for use, for example, as orthopedic implants are described herein. In one example, a composite material for use as a scaffold includes a thermoplastic polymer forming a porous matrix that has continuous porosity and a plurality of pores. The porosity and the size of the pores are selectively formed during synthesis of the composite material. The example composite material also includes a plurality of a anisometric calcium phosphate particles integrally formed, embedded in, or exposed on a surface of the porous matrix. The calcium phosphate particles provide one or more of reinforcement, bioactivity, or bioresorption.
摘要翻译： 本文描述了用作例如整形外科植入物的合成复合材料。 在一个实例中，用作支架的复合材料包括形成具有连续孔隙率和多个孔的多孔基体的热塑性聚合物。 在合成复合材料过程中选择性地形成孔隙率和孔径。 该示例性复合材料还包括一体形成，嵌入或暴露于多孔基质的表面上的多个不等尺寸的磷酸钙颗粒。 磷酸钙颗粒提供一种或多种增强，生物活性或生物再吸收。
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公开(公告)号：US20190083282A1
公开(公告)日：2019-03-21
申请号：US16134453
申请日：2018-09-18
IPC分类号： A61F2/44 , A61L27/56 , B29C67/20 , A61F2/28 , A61L27/54 , A61L27/26 , A61L27/18 , A61L27/12 , C08J9/36 , C08J9/28 , C08J9/00 , A61L27/46 , A61F2/30
摘要： Implantable devices for orthopedic, including spine and other uses are formed of porous reinforced polymer scaffolds. Scaffolds include a thermoplastic polymer forming a porous matrix that has continuously interconnected pores. The porosity and the size of the pores within the scaffold are selectively formed during synthesis of the composite material, and the composite material includes a plurality of reinforcement particles integrally formed within and embedded in the matrix and exposed on the pore surfaces. The reinforcement particles provide one or more of reinforcement, bioactivity, or bioresorption.
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公开(公告)号：US20210000611A9
公开(公告)日：2021-01-07
申请号：US16134453
申请日：2018-09-18
IPC分类号： A61F2/44 , A61L27/56 , B29C67/20 , A61F2/28 , A61L27/54 , A61L27/26 , A61L27/18 , A61L27/12 , C08J9/36 , C08J9/28 , C08J9/00 , A61L27/46 , A61F2/30
摘要： Implantable devices for orthopedic, including spine and other uses are formed of porous reinforced polymer scaffolds. Scaffolds include a thermoplastic polymer forming a porous matrix that has continuously interconnected pores. The porosity and the size of the pores within the scaffold are selectively formed during synthesis of the composite material, and the composite material includes a plurality of reinforcement particles integrally formed within and embedded in the matrix and exposed on the pore surfaces. The reinforcement particles provide one or more of reinforcement, bioactivity, or bioresorption.
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公开(公告)号：US20080206297A1
公开(公告)日：2008-08-28
申请号：US12039666
申请日：2008-02-28
CPC分类号： A61F2/4455 , A61F2/28 , A61F2/30965 , A61F2/4465 , A61F2002/2817 , A61F2002/2835 , A61F2002/30006 , A61F2002/30011 , A61F2002/30034 , A61F2002/30062 , A61F2002/30065 , A61F2002/30225 , A61F2002/30235 , A61F2002/30622 , A61F2002/30904 , A61F2002/3092 , A61F2002/30957 , A61F2210/0004 , A61F2210/0071 , A61F2230/0069 , A61F2250/0015 , A61F2250/0018 , A61F2250/0023 , A61F2250/0031 , A61L27/12 , A61L27/18 , A61L27/26 , A61L27/46 , A61L27/54 , A61L27/56 , B29C67/202 , C08J9/0066 , C08J9/28 , C08J9/36
摘要： Synthetic composite materials for use, for example, as orthopedic implants are described herein. In one example, a composite material for use as a scaffold includes a thermoplastic polymer forming a porous matrix that has continuous porosity and a plurality of pores. The porosity and the size of the pores are selectively formed during synthesis of the composite material. The example composite material also includes a plurality of a anisometric calcium phosphate particles integrally formed, embedded in, or exposed on a surface of the porous matrix. The calcium phosphate particles provide one or more of reinforcement, bioactivity, or bioresorption.
摘要翻译： 本文描述了用作例如整形外科植入物的合成复合材料。 在一个实例中，用作支架的复合材料包括形成具有连续孔隙率和多个孔的多孔基体的热塑性聚合物。 在合成复合材料过程中选择性地形成孔隙率和孔径。 该示例性复合材料还包括一体形成，嵌入或暴露于多孔基质的表面上的多个不等尺寸的磷酸钙颗粒。 磷酸钙颗粒提供一种或多种增强，生物活性或生物再吸收。
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