公开(公告)号：US08491644B1

公开(公告)日：2013-07-23

申请号：US11360021

申请日：2006-02-21

申请人： Gary Carson ,  Gary Gruzecki ,  Steve Whitehead

发明人： Gary Carson ,  Gary Gruzecki ,  Steve Whitehead

IPC分类号： A61F7/00

CPC分类号： A61F7/02 ,  A61F2007/0056 ,  A61F2007/0086 ,  A61F2007/0226 ,  A61F2007/126

摘要： A portable patient cooling apparatus is provided that includes a self-contained refrigerator and on-board power storage supply for stand alone operation. The apparatus is interconnectable to one or more heat exchange devices (e.g. patient contact pads or intravascular catheters) through which a cooled fluid may be circulated for patient cooling. Such fluid may be liquid contained within a reservoir comprising the apparatus during periods of non-use. The apparatus preferably defines a total volume of less than about 0.04 m3, while having a total weight of less than about 15 kg to yield a total circulated fluid cooling capacity of at least 200 watts.

摘要翻译： 提供一种便携式病人冷却装置，其包括独立操作的独立冰箱和车载蓄电源。 该装置可连接到一个或多个热交换装置（例如患者接触垫或血管内导管），冷却的流体可以通过该装置循环用于患者冷却。 在不使用期间，这种流体可以是包含在包括该装置的储存器内的液体。 该装置优选地限定总体积小于约0.04m 3，而总重量小于约15kg，以产生至少200瓦特的总循环流体冷却能力。

公开(公告)号：US20070244475A1

公开(公告)日：2007-10-18

申请号：US11737036

申请日：2007-04-18

申请人： GARY CARSON ,  MARC VOORHEES

发明人： GARY CARSON ,  MARC VOORHEES

IPC分类号： A61M37/00 ,  A61F7/00 ,  A61B18/18 ,  F25B17/08

CPC分类号： F25B17/08 ,  A61F7/0085 ,  A61F2007/0292 ,  A61F2007/126 ,  A61M5/1424 ,  A61M5/1483 ,  A61M5/445 ,  A61M2205/3606 ,  A61M2205/366 ,  F25D2400/12

摘要： A portable apparatus and method for providing a cooled liquid for vascular administration are disclosed. The portable apparatus includes a source of liquid for vascular administration, a cooling reservoir for receiving liquid from the source, and a sorption-based heat exchanger for cooling liquid in the cooling reservoir by a sorption-based process. The heat exchanger may include an evaporative area for receiving and vaporizing a refrigerant, a sorptive material for sorping vaporized refrigerant, and a heat exchange member for conducting thermal energy from liquid in the cooling reservoir into the evaporative area. Additional componentry may be provided for fluidly interconnecting and controlling the flow of liquid from the source to the cooling reservoir and from the cooling reservoir to a vascular interface device. Such componentry may be conveniently packaged in a sterilized manner together with at least the cooling reservoir.

摘要翻译： 公开了用于提供用于血管给药的冷却液体的便携式装置和方法。 便携式装置包括用于血管给药的液体源，用于从源接收液体的冷却储存器和用于通过基于吸附的方法冷却冷却储存器中的液体的吸附型热交换器。 热交换器可以包括用于接收和蒸发制冷剂的蒸发区域，用于吸附蒸发的制冷剂的吸附材料，以及用于将来自冷却储存器中的液体的热能传导到蒸发区域的热交换构件。 可以提供另外的组件，用于流体地互连和控制从源到冷却储存器以及从冷却储存器到血管界面装置的液体流动。 这种组合物可以与至少冷却储存器一起以消毒方式方便地包装。

公开(公告)号：US5468449A

公开(公告)日：1995-11-21

申请号：US272524

申请日：1994-07-11

申请人： Axel Sjogren ,  Gary Carson ,  Steven Estergreen ,  Timothy Taga ,  Rodger Stewart

发明人： Axel Sjogren ,  Gary Carson ,  Steven Estergreen ,  Timothy Taga ,  Rodger Stewart

IPC分类号： A61M1/36 ,  A61M1/14 ,  A61M1/16 ,  A61M1/22 ,  B01D63/02 ,  F28D9/00 ,  F28F21/06 ,  B01D61/00

CPC分类号： B01D63/026 ,  A61M1/1629 ,  A61M1/1698 ,  B01D63/02 ,  B01D63/021 ,  F28D9/0025 ,  F28F21/062 ,  A61M2205/366 ,  A61M2207/00 ,  B01D2313/38

摘要： A method for manufacturing an exchanger includes the steps of folding sheet material in a series of pleats, placing the folded sheet material in a casing having an opening defined by walls with distal edges, covering the distal edges with end portions of the sheet material, and affixing a cover to the casing by simultaneously melting a portion of the cover and the sheet covered distal edges of the walls, and contacting the cover with the sheet material covering the distal edges of the walls. The method may also include melting a portion of the cover and/or the casing and placing the melted cover on the casing so that the melted portion contacts pleats of the sheet material, and permitting the melted material to cool and solidify and form a bond with the sheet material. The method may further include melting the side edges of the folded sheet material as well as the four edges of the casing and cover and the inner surfaces of the side walls, and then bonding the side walls to the melted folded material and the melted casing cover edges.

摘要翻译： 一种制造交换器的方法包括以下步骤：将片材折叠成一系列褶皱，将折叠的片材放置在具有由具有远侧边缘的壁限定的开口的壳体中，用片材的端部覆盖远侧边缘，以及 通过同时熔化所述盖的一部分和覆盖所述壁的远侧边缘的片材，并将所述盖与覆盖所述壁的远侧边缘的所述片材接触而将盖子附着到所述壳体。 该方法还可以包括熔化盖和/或壳体的一部分并将熔融的盖放置在壳体上，使得熔融部分接触片材的褶皱，并且允许熔融的材料冷却并固化并形成与 片材。 该方法还可以包括熔化折叠的片材的侧边缘以及壳体和盖子的四个边缘以及侧壁的内表面，然后将侧壁粘合到熔化的折叠材料和熔化的壳体盖 边缘。

公开(公告)号：US20060015056A1

公开(公告)日：2006-01-19

申请号：US11130872

申请日：2005-05-17

申请人： Bruce Ellingboe ,  John Kappus ,  Gary Carson ,  Kevin Kollar

发明人： Bruce Ellingboe ,  John Kappus ,  Gary Carson ,  Kevin Kollar

IPC分类号： A61M37/00 ,  A61M1/00

CPC分类号： A61M1/32 ,  A61M1/322 ,  A61M1/3621 ,  A61M1/3624 ,  A61M1/3626 ,  A61M1/3632 ,  A61M1/3639 ,  A61M1/3641 ,  A61M1/3643 ,  A61M1/3644 ,  A61M1/3663 ,  A61M1/3664 ,  A61M1/3666 ,  A61M1/3667 ,  A61M2205/123 ,  A61M2205/128 ,  A61M2205/3389 ,  A61M2205/505 ,  A61M2205/705 ,  A61M2205/707 ,  A61M2209/082 ,  G06F19/00

摘要： A disposable cartridge for use in extracorporeal blood perfusions systems that have a control unit for controlling the flow of fluids. The cartridge has a housing defining a plurality of internal passageways that connect to a cardiopulmonary circuit, a cardioplegia circuit and a suction circuit. The cartridge may be fitted with one or more of a bubble trap, a filter, and a valve.

公开(公告)号：US20080027368A1

公开(公告)日：2008-01-31

申请号：US11869451

申请日：2007-10-09

申请人： Kevin Kollar ,  Bruce Ellingboe ,  John Kappus ,  Gary Carson

发明人： Kevin Kollar ,  Bruce Ellingboe ,  John Kappus ,  Gary Carson

IPC分类号： A61M1/14

CPC分类号： A61M1/3621 ,  A61M1/1698 ,  A61M1/3643 ,  A61M1/3644 ,  A61M1/3664 ,  A61M1/3666 ,  A61M1/3667 ,  A61M2205/12 ,  A61M2205/502

摘要： A disposable cartridge for use in extracorporeal blood perfusions systems that have a control unit for controlling the flow of fluids. The cartridge has a housing defining a plurality of internal passageways that connect to a cardiopulmonary circuit, a cardioplegia circuit and a suction circuit. The cartridge may be fitted with one or more of a bubble trap, a filter, and a valve.

摘要翻译： 用于体外血液灌注系统的一次性药筒，其具有用于控制流体流动的控制单元。 药筒具有限定连接到心肺电路，心麻痹电路和吸入电路的多个内部通道的壳体。 墨盒可以装配一个或多个气泡阱，过滤器和阀。

公开(公告)号：US20050060012A1

公开(公告)日：2005-03-17

申请号：US10666902

申请日：2003-09-17

申请人： Marc Voorhees ,  Gary Carson

发明人： Marc Voorhees ,  Gary Carson

IPC分类号： A61F7/00 ,  A61F7/02 ,  A61F7/10 ,  A61N7/00

CPC分类号： A61F7/02 ,  A61B8/0816 ,  A61F7/10 ,  A61N7/00

摘要： A method and system is provided to induce mild hypothermia in a patient through controlled heating of the preoptic anterior hypothalamus (POAH) in conjunction with cooling of patient's body. The system employs an ultrasound transducer that may be positioned extracorporeally to a patient skull for emitting ultrasound energy to the POAH. The ultrasound energy heats the POAH to inhibit thermoregulatory responses of the body such that a cooling means may more effectively cool bodily tissue in order to reduce a patient's core body temperature. Feedback sensors may be positioned at various locations on the patient in order to monitor the patient's core body temperature. A control apparatus included with the system controls the amount of heat the POAH receives and the amount of cooling the body receives based on the feedback signals from the sensors.

摘要翻译： 提供一种方法和系统，通过控制加热前视前下丘脑（POAH）与患者身体的冷却来诱导患者轻度低温。 该系统采用超声换能器，该超声换能器可以被定位在患者颅骨的体外以向POAH发射超声波能量。 超声能量加热POAH以抑制身体的体温调节反应，使得冷却装置可以更有效地冷却身体组织，以减少患者的核心体温。 反馈传感器可以位于患者的不同位置，以便监测患者的核心体温。 系统中包括的控制装置根据来自传感器的反馈信号来控制POAH接收的热量和身体的冷却量。

公开(公告)号：US06692518B2

公开(公告)日：2004-02-17

申请号：US10087630

申请日：2002-02-27

申请人： Gary Carson

发明人： Gary Carson

IPC分类号： A61F700

CPC分类号： A61F7/0085 ,  A61F7/02 ,  A61F2007/0054 ,  A61F2007/0288 ,  A61M1/369 ,  A61M2205/3372

摘要： A temperature control system provides for the optimal management of patient temperature during a surgical procedure, such as those which require the patient to on bypass. The system employs a plurality of controllers as well as a plurality of temperature control means in order to provide optimal temperature control. In one configuration of the invention, controllers for each of the heat exchange devices may be interconnected using a data link. The connection may provide for a master/slave relationship wherein temperature sensors included in each system are employable as temperature feedback for initiating temperature changes. This device may be configured such that it operates in conjunction with another device or provides stand alone temperature control.

摘要翻译： 温度控制系统提供在外科手术期间对患者体温的最佳管理，例如需要患者绕行的那些。 该系统采用多个控制器以及多个温度控制装置，以便提供最佳的温度控制。 在本发明的一个配置中，用于每个热交换装置的控制器可以使用数据链路互连。 连接可以提供主/从关系，其中包括在每个系统中的温度传感器可用作用于启动温度变化的温度反馈。 该装置可以被配置为使得其与另一装置结合操作或提供独立的温度控制。

公开(公告)号：US06660027B2

公开(公告)日：2003-12-09

申请号：US09976178

申请日：2001-10-11

申请人： Gary Gruszecki ,  Bruce Ellingboe ,  Gary Carson

发明人： Gary Gruszecki ,  Bruce Ellingboe ,  Gary Carson

IPC分类号： A61F200

CPC分类号： A61F7/0085 ,  A61B2017/00084 ,  A61F2007/0054

摘要： An improved patient temperature exchange system and method is disclosed for use with one or more interconnectable patient contact pads. In one embodiment, the system includes a circulating pump for drawing fluid through the interconnected pad(s) under negative pressure, and for pumping the fluid through one of more heat exchange devices into a circulating reservoir. A make-up reservoir may be provided for gravity fluid flow into the circulating reservoir during the filling of the interconnectable pad(s) and for receiving fluid upon emptying of the interconnectable pad(s). During normal heating/cooling operations, the circulated fluid does not pass through the make-up reservoir, thereby yielding a highly responsive system. The make-up and circulatory reservoirs may be directly interconnected, with the make-up reservoir maintained at atmospheric pressure (e.g. via a non-spill vent). To reliably maintain the desired negative pressure in the interconnectable pad(s), the system may provide for fluid pressure sensing on the inlet side of the circulating pump. The sensed pressure may be utilized to control the speed of the circulating pump. The system may further provide for the positioning of pressure drop a componentry on the outlet side of the circulating pump, thereby further facilitating the maintenance of a desired negative pressure within the interconnected pad(s). A bypass fluid line may also be included to provide for fluid preconditioning prior to interconnection of and/or fluid flow through the pad(s). Multiple temperature sensors and an interface for an external patient temperature input may also be provided for enhanced fluid heating/cooling control.

公开(公告)号：US5470531A

公开(公告)日：1995-11-28

申请号：US970781

申请日：1992-11-03

申请人： Axel Sjogren ,  Gary Carson ,  Steve Estergreen ,  Timothy Taga ,  Rodger Stewart

发明人： Axel Sjogren ,  Gary Carson ,  Steve Estergreen ,  Timothy Taga ,  Rodger Stewart

IPC分类号： A61M1/36 ,  A61M1/14 ,  A61M1/16 ,  A61M1/22 ,  B01D63/02 ,  F28D9/00 ,  F28F21/06 ,  B01D61/00

CPC分类号： B01D63/026 ,  A61M1/1629 ,  A61M1/1698 ,  B01D63/02 ,  B01D63/021 ,  F28D9/0025 ,  F28F21/062 ,  A61M2205/366 ,  A61M2207/00 ,  B01D2313/38

摘要： An exchanger for oxygenating blood includes a casing having walls and a cavity, sheet material with first and second ends covering distal edges of the walls, and a cover extending over the cavity to sandwich the first and second ends of the sheet material between the cover and the edges of the walls. The cover is melted into the sheet material and the distal edges of the walls. In another embodiment, a blood oxygenator includes a first compartment having a closed casing divided by a folded sheet of membrane material forming a first blood chamber and a first gas chamber. The casing has first and second manifolds in fluid communication with the first blood chamber. A second compartment is interconnected with the first compartment and has a closed casing divided by a folded sheet of membrane material forming a second blood chamber and a second gas chamber. The casing has third and fourth spaced apart manifolds in fluid communication with the second blood chamber. A first conduit connects an outlet of the first manifold to the an inlet of the third manifold, and a second conduit connects an outlet of the fourth manifold to an inlet of the second manifold.

摘要翻译： 用于对血液充血的交换器包括具有壁和空腔的壳体，具有覆盖壁的远侧边缘的第一和第二端的片材，以及在空腔上延伸以将片材的第一和第二端夹在盖和 墙壁的边缘。 盖子熔化成板材和壁的远端边缘。 在另一个实施方案中，血液充氧器包括具有封闭壳体的第一隔室和由形成第一血液腔室和第一气体室的膜材料的折叠片材分隔开。 壳体具有与第一血液腔流体连通的第一和第二歧管。 第二隔室与第一隔室相互连接并且具有由形成第二血液室和第二气体室的膜材料的折叠片分隔的封闭壳体。 壳体具有与第二血液腔流体连通的第三和第四间隔开的歧管。 第一导管将第一歧管的出口连接到第三歧管的入口，并且第二导管将第四歧管的出口连接到第二歧管的入口。