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    Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue
    1.
    发明授权
    Implantable pulse generator systems and methods for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue 有权
    用于提供对肌肉和/或神经和/或中枢神经系统组织的功能和/或治疗刺激的可植入脉冲发生器系统和方法

    公开(公告)号：US09205255B2

    公开(公告)日：2015-12-08

    申请号：US11517170

    申请日：2006-09-07

    申请人： Robert B. Strother ,  Geoffrey B. Thrope

    发明人： Robert B. Strother ,  Geoffrey B. Thrope

    IPC分类号： A61N1/378 ,  A61N1/36 ,  A61N1/372 ,  A61N1/375 ,  A61N1/05

    CPC分类号： A61N1/36007 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/3605 ,  A61N1/36071 ,  A61N1/37229 ,  A61N1/37252 ,  A61N1/375 ,  A61N1/3754 ,  A61N1/3758 ,  A61N1/3787

    摘要： Improved assemblies, systems, and methods provide a stimulation system for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination. The stimulation system includes a pulse generator including a housing sized and configured for implantation in subcutaneous tissue, circuitry carried within the housing, the circuitry operable for generating electrical stimulation pulses, and a rechargeable battery coupled to the circuitry and carried within the housing, the rechargeable battery including a battery capacity. The circuitry is adapted to suspend the generation of electrical stimulation pulses at a first remaining battery capacity, and the circuitry is adapted to enter a dormant mode at a second remaining battery capacity. The first battery remaining capacity may be greater than or equal to the second remaining battery capacity. At the second remaining battery capacity, only a safety margin battery capacity remains.

    摘要翻译： 改进的装配，系统和方法提供用于肌肉，神经或中枢神经系统组织或任何组合的假体或治疗刺激的刺激系统。 所述刺激系统包括脉冲发生器，所述脉冲发生器包括尺寸和构造用于植入皮下组织的壳体，所述壳体内承载的电路，可操作以产生电刺激脉冲的电路，以及耦合到所述电路并在所述壳体内承载的可充电电池， 电池包括电池容量。 电路适于暂停在第一剩余电池容量下的电刺激脉冲的产生，并且电路适于以第二剩余电池容量进入休眠模式。 第一电池剩余容量可以大于或等于第二剩余电池容量。 在第二个剩余电池容量下，仅剩下一个安全边际电池容量。

    Implantable pulse generator power management
    3.
    发明授权
    Implantable pulse generator power management 有权
    可植入脉冲发生器电源管理

    公开(公告)号：US08165692B2

    公开(公告)日：2012-04-24

    申请号：US11824892

    申请日：2007-07-03

    申请人： Robert B Strother ,  Joseph J Mrva ,  Geoffrey B Thrope

    发明人： Robert B Strother ,  Joseph J Mrva ,  Geoffrey B Thrope

    IPC分类号： A61N1/08 ,  A61B19/00

    CPC分类号： A61N1/37276 ,  A61N1/36003 ,  A61N1/36071 ,  A61N1/37223 ,  Y10S128/903 ,  Y10S128/904

    摘要： Improved assemblies, systems, and methods provide an implantable pulse generator for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination thereof. The implantable pulse generator is sized and configured to be implanted subcutaneously in a tissue region. The implantable pulse generator includes an electrically conductive case of a laser welded titanium material. Control circuitry is located within the case. The control circuitry includes a rechargeable power source, a receive coil for receiving an RF magnetic field to recharge the power source, and a microcontroller for control of the implantable pulse generator. The improved assemblies, systems, and methods also provide a stimulation system for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination thereof. The stimulation system provides at least one electrically conductive surface, a lead connected to the electrically conductive surface, and an implantable pulse generator electrically connected to the lead.

    摘要翻译： 改进的组件，系统和方法提供了用于假体或治疗性刺激肌肉，神经或中枢神经系统组织的植入式脉冲发生器或其任何组合。 可植入脉冲发生器的尺寸和构造被皮下植入组织区域。 可植入脉冲发生器包括激光焊接钛材料的导电壳体。 控制电路位于外壳内。 控制电路包括可充电电源，用于接收RF磁场以对电源再充电的接收线圈，以及用于控制可植入脉冲发生器的微控制器。 改进的组合件，系统和方法还提供用于肌肉，神经或中枢神经系统组织或其任何组合的假体或治疗刺激的刺激系统。 刺激系统提供至少一个导电表面，连接到导电表面的引线以及电连接到引线的可植入脉冲发生器。

    Devices, Systems, and methods employing a molded nerve cuff electrode
    5.
    发明申请
    Devices, Systems, and methods employing a molded nerve cuff electrode 审中-公开
    使用模制神经袖口电极的装置，系统和方法

    公开(公告)号：US20100298920A1

    公开(公告)日：2010-11-25

    申请号：US12804984

    申请日：2010-08-03

    申请人： Joseph J. Mrva ,  James Coburn ,  Robert B. Strother ,  Geoffrey B. Thrope

    发明人： Joseph J. Mrva ,  James Coburn ,  Robert B. Strother ,  Geoffrey B. Thrope

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0556

    摘要： Devices, systems, and methods for recording, and/or stimulation, and/or blocking of a nerve make use of a molded cuff electrode. An electrically conductive surface is coupled to an inside surface of the elastic body of the cuff. The elastic body of the cuff is formed from a substantially homogeneous material, and the electrically conductive surface and the body assume a coiled configuration in the natural state of the cuff. An applicator tool having a body and a slider are used to implant the cuff electrode about a nerve.

    摘要翻译： 用于记录和/或刺激和/或阻断神经的装置，系统和方法利用模压的袖带电极。 导电表面联接到袖带的弹性体的内表面。 袖带的弹性体由基本均匀的材料形成，并且导电表面和本体在袖带的自然状态下呈现卷曲构型。 使用具有主体和滑块的涂抹器工具将袖带电极植入在神经周围。

    Implantable pulse generator for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue
    6.
    发明授权
    Implantable pulse generator for providing functional and/or therapeutic stimulation of muscles and/or nerves and/or central nervous system tissue 有权
    用于提供肌肉和/或神经和/或中枢神经系统组织的功能和/或治疗刺激的植入式脉冲发生器

    公开(公告)号：US07813809B2

    公开(公告)日：2010-10-12

    申请号：US11150535

    申请日：2005-06-10

    申请人： Robert B. Strother ,  Joseph J. Mrva ,  Geoffrey B. Thrope

    发明人： Robert B. Strother ,  Joseph J. Mrva ,  Geoffrey B. Thrope

    IPC分类号： A61N1/08 ,  A61B19/00

    CPC分类号： A61N1/37235 ,  A61B5/0031 ,  A61B5/0488 ,  A61B5/7232 ,  A61B2560/0209 ,  A61N1/36003 ,  A61N1/37247 ,  Y10S128/903 ,  Y10S128/904

    摘要： An implantable pulse generator for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination is sized and configured to be implanted in subcutaneous tissue. The implantable pulse generator includes an electrically conductive laser welded titanium case. Control circuitry is located within the case, and includes a primary cell or rechargeable power source, a receive coil for receiving an RF magnetic field to recharge the rechargeable power source, non-inductive wireless telemetry circuitry, and a microcontroller for control of the implantable pulse generator. A stimulation system for prosthetic or therapeutic stimulation of muscles, nerves, or central nervous system tissue, or any combination comprises at least one electrically conductive surface, a lead connected to the electrically conductive surface, and an implantable pulse generator electrically connected to the lead.

    摘要翻译： 用于假体或治疗性刺激肌肉，神经或中枢神经系统组织或任何组合的可植入脉冲发生器的大小和构造被植入皮下组织。 可植入脉冲发生器包括导电激光焊接钛壳。 控制电路位于壳体内，并且包括主电池或可充电电源，用于接收RF磁场以对可再充电电源进行再充电的接收线圈，非感性无线遥测电路和用于控制可植入脉冲的微控制器 发电机。 用于对肌肉，神经或中枢神经系统组织或任何组合的假体或治疗刺激的刺激系统包括至少一个导电表面，连接到导电表面的引线和电连接到引线的可植入脉冲发生器。

    Percutaneous electrode assemblies, systems, and methods for providing highly selective functional or therapeutic neuromuscular stimulation
    8.
    发明申请
    Percutaneous electrode assemblies, systems, and methods for providing highly selective functional or therapeutic neuromuscular stimulation 审中-公开
    用于提供高选择性功能或治疗性神经肌肉刺激的经皮电极组件，系统和方法

    公开(公告)号：US20100100158A1

    公开(公告)日：2010-04-22

    申请号：US12653528

    申请日：2009-12-15

    申请人： Geoffrey B. Thrope ,  Robert B. Strother ,  Joseph J. Mrva

    发明人： Geoffrey B. Thrope ,  Robert B. Strother ,  Joseph J. Mrva

    IPC分类号： A61N1/05 ,  A61N1/378

    CPC分类号： A61N1/32 ,  A61N1/0551 ,  Y10S128/907

    摘要： Percutaneous electrode assemblies, systems, and methods make possible the providing of short-term therapy or diagnostic testing by providing electrical connections between muscles or nerves inside the body and stimulus generators or recording instruments carried outside the body. The percutaneous electrodes include a flexible body having an electrically conductive region, a tissue penetrating region, and a percutaneous lead electrically coupled to the electrically conductive region. An anchoring element is positioned on the flexible body to resist movement of the electrically conductive region within tissue. An introducer is sized and configured to receive the flexible body and shield the anchoring element from contact with tissue while the electrically conductive region is placed to a desired position within tissue, and accommodates advancement of the anchoring element beyond the interior lumen for contact with tissue to resist movement of the electrically conductive region placed in the desired position.

    摘要翻译： 经皮电极组件，系统和方法可以通过在体内的肌肉或神经之间提供短期治疗或诊断测试，以及在体外携带的刺激发生器或记录仪器。 经皮电极包括具有导电区域，组织穿透区域和电耦合到导电区域的经皮引线的柔性体。 锚定元件定位在柔性体上以抵抗组织内导电区域的移动。 导引器的尺寸和构造被设计成接收柔性体并且屏蔽锚固元件免受与组织的接触，同时将导电区域放置在组织内的期望位置，并且容纳锚定元件超出内腔以与组织接触 阻止放置在所需位置的导电区域的移动。