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公开(公告)号：US20240325686A1
公开(公告)日：2024-10-03
申请号：US18740020
申请日：2024-06-11
CPC分类号： A61M25/0017 , A61L29/146 , A61M25/005 , A61M25/10186 , A61M2025/0059 , A61M2210/1067
摘要： An apparatus according to certain embodiments generally includes an elongated tubular member having a proximal end and an opposite distal end, and an inflatable balloon surrounding the distal end. The elongated tubular member comprises an outer tube, a non-collapsible inner tube positioned within the outer tube, and a compressible material positioned between the outer tube and the inner tube.
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公开(公告)号：US12097288B2
公开(公告)日：2024-09-24
申请号：US17831946
申请日：2022-06-03
申请人： Cristcot LLC
发明人： Jennifer J. Davagian
IPC分类号： A61K9/02 , A61K9/00 , A61K31/573 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/20 , A61M31/00
CPC分类号： A61K9/025 , A61K9/0031 , A61K9/02 , A61K31/573 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/20 , A61M31/007 , A61M2210/1064 , A61M2210/1067
摘要： The present invention relates, in various embodiments, to formulations comprising hydrocortisone and silicon dioxide. In additional embodiments, the invention relates to suppositories comprising hydrocortisone and silicon dioxide. The formulations of the present invention are useful for administration to patients who have gastrointestinal diseases and disorders such as, for example, inflammatory bowel disease.
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公开(公告)号：US20240207182A1
公开(公告)日：2024-06-27
申请号：US18588938
申请日：2024-02-27
申请人： Cristcot LLC
IPC分类号： A61K9/02 , A61K9/00 , A61K31/573 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/20 , A61M31/00
CPC分类号： A61K9/025 , A61K9/0031 , A61K9/02 , A61K31/573 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/20 , A61M31/007 , A61M2210/1064 , A61M2210/1067
摘要： The present invention relates, in various embodiments, to formulations comprising hydrocortisone and silicon dioxide. In additional embodiments, the invention relates to suppositories comprising hydrocortisone and silicon dioxide. The formulations of the present invention are useful for administration to patients who have gastrointestinal diseases and disorders such as, for example, inflammatory bowel disease.
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公开(公告)号：US20240207180A1
公开(公告)日：2024-06-27
申请号：US18588687
申请日：2024-02-27
申请人： Cristcot LLC
IPC分类号： A61K9/02 , A61K9/00 , A61K31/573 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/20 , A61M31/00
CPC分类号： A61K9/025 , A61K9/0031 , A61K9/02 , A61K31/573 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/20 , A61M31/007 , A61M2210/1064 , A61M2210/1067
摘要： The present invention relates, in various embodiments, to formulations comprising hydrocortisone and silicon dioxide. In additional embodiments, the invention relates to suppositories comprising hydrocortisone and silicon dioxide. The formulations of the present invention are useful for administration to patients who have gastrointestinal diseases and disorders such as, for example, inflammatory bowel disease.
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公开(公告)号：US20240197629A1
公开(公告)日：2024-06-20
申请号：US18588820
申请日：2024-02-27
申请人： Cristcot LLC
IPC分类号： A61K9/02 , A61K9/00 , A61K31/573 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/20 , A61M31/00
CPC分类号： A61K9/025 , A61K9/0031 , A61K9/02 , A61K31/573 , A61K47/02 , A61K47/10 , A61K47/14 , A61K47/20 , A61M31/007 , A61M2210/1064 , A61M2210/1067
摘要： The present invention relates, in various embodiments, to formulations comprising hydrocortisone and silicon dioxide. In additional embodiments, the invention relates to suppositories comprising hydrocortisone and silicon dioxide. The formulations of the present invention are useful for administration to patients who have gastrointestinal diseases and disorders such as, for example, inflammatory bowel disease.
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公开(公告)号：US20240075223A1
公开(公告)日：2024-03-07
申请号：US18505101
申请日：2023-11-08
发明人： John D. Hoekman , Michael Hite , Alan Brunelle , Joel Relethford
CPC分类号： A61M15/08 , A61M15/0021 , A61M16/127 , B05B1/14 , B05B7/08 , A61M16/208 , A61M2210/0612 , A61M2210/0618 , A61M2210/1067 , A61M2210/1475
摘要： A nozzle for use in delivering a mixture of aerosol propellant and drug formulation. The nozzle includes a drug product inlet configured to receive a mixture of aerosolized propellant and an intranasal dosage form. The inlet is disposed at the proximal end. A nozzle body is secured to the drug product inlet. Two or more channels are disposed within the body. Two or more orifice apertures are disposed at the distal end of the nozzle.
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公开(公告)号：US20230414392A1
公开(公告)日：2023-12-28
申请号：US18464269
申请日：2023-09-11
CPC分类号： A61F5/0093 , A61M35/006 , A61M35/00 , A61M2202/04 , A61M2205/6018 , A61M2210/1067
摘要： The present disclosure provides devices for preventing or absorbing fluid (e.g., sweat) and/or odors from the intergluteal cleft of a subject. In some embodiments, the present disclosure provides devices for treating or preventing hemorrhoids and methods of using same.
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公开(公告)号：US20230166009A1
公开(公告)日：2023-06-01
申请号：US17921798
申请日：2021-04-28
发明人： Fred Göbel
CPC分类号： A61L29/14 , A61M25/0017 , A61M25/1002 , A61L29/085 , A61M25/0045 , A61M2210/1067 , A61M2202/068 , A61L2209/22
摘要： The invention is directed to a catheter-like system which dwells temporarily or even continuously in the body of a patient and which serves for the closed delivery and/or discharge of odour-intensive substances, wherein the release of foul-smelling substances is reduced to the greatest possible extent by the system wall having a multi-layer structure that incorporates a proportion of barrier materials, and an odour-neutral decompression of gaseous fractions arising in the body and discharged into the system is ensured. The system comprises in particular a structure like a tubular film, by which an internal space to be reached in the body is connected to a container, arranged outside the body, for receiving the respective substances that are to be delivered and/or discharged. At the end positioned inside the body, the tube structure is provided with a retaining and/or sealing balloon element, which secures the system in the body. All of the film-based constituent parts of the system that are arranged outside the body, including the film-like delivering and/or discharging tube structure and the container preferably configured in the form of a bag, incorporate at least one barrier-producing layer of ethylene vinyl alcohol copolymer (EVOH), polyvinylidene chloride (PVDC) and/or polyamide (PA), which is combined with at least one carrier layer made of a robust, mechanically loadable, preferably elastic material, for example polyurethane (PUR). The system moreover ensures a continuous decompression of gaseous constituents from the internal space of the system, by a degassing device which is arranged in a particular manner relative to the delivering and/or discharging lumen and by which the adsorbing or filtering, degassing unit is protected against direct exposure to the substances that are to be delivered and/or discharged.
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公开(公告)号：US11648359B2
公开(公告)日：2023-05-16
申请号：US16671587
申请日：2019-11-01
发明人： Ralph Sias , Alexandra Do , Nikolai Poulsen , Boun Pravong , Kennii Pravongviengkham , Timothy McMorrow , W. F. Anthony Miles
CPC分类号： A61M13/003 , A61B17/3423 , A61B17/3474 , A61B2017/00278 , A61B2017/00818 , A61B2017/00862 , A61B2017/3447 , A61M2202/0225 , A61M2205/3334 , A61M2205/3341 , A61M2205/3344 , A61M2205/3355 , A61M2210/1067 , A61M2202/0225 , A61M2202/0007
摘要： Pressure conditioning systems for supplying insufflation gas to an open-ended body conduit such as a rectal cavity during a transanal minimally invasive surgery (TAMIS) procedure can reduce billowing of walls of the body conduit. A pressure conditioning system can include a pressure storage component, an accumulator, and a flow restrictor. The pressure storage component can include a variable volume reservoir that is biased to a relatively low volume state. The flow restrictor can include insufflation tubing with a restrictor plate having a relatively low diameter orifice. The pressure storage component, accumulator, and flow restrictor can be fluidly connected in various orders in series or as side branches from a gas flow conduit. Despite a pulsed or otherwise discontinuous insufflation gas flow and leakage and absorption from the body conduit, the pressure conditioning system can maintain a constant pressure within the body conduit.
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公开(公告)号：US20190247632A1
公开(公告)日：2019-08-15
申请号：US16270708
申请日：2019-02-08
申请人： LK Innovations, LLC
发明人： Pedro P. Llaneza , Matthew Solar
IPC分类号： A61M31/00
CPC分类号： A61M31/00 , A61M25/10186 , A61M2210/1067
摘要： A device is provided for delivery of a therapeutic agent to the anal and perianal regions. The device includes a deployable internal anchor adapted to comfortably anchor the device in the anal canal, a shaft adapted to store and release the agent to the anal canal, and an external bumper adapted to store and release the agent to the perianal tissue and externally anchor the device.
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