公开(公告)号：US09943566B2

公开(公告)日：2018-04-17

申请号：US15461320

申请日：2017-03-16

申请人： Geoffrey Brooks Consultants, LLC

发明人： Geoffrey J. Brooks ,  Rajendra S. Bhatnagar ,  Andrew P. Banham

IPC分类号： C07K5/10 ,  C07K7/06 ,  A61Q19/00 ,  A61Q19/08 ,  A61K38/00 ,  A61K38/18 ,  A61K8/64 ,  A61K38/08 ,  A61K9/00

CPC分类号： A61K38/1841 ,  A61K8/64 ,  A61K9/0014 ,  A61K9/06 ,  A61K38/08 ,  A61K47/14 ,  A61Q19/08

摘要： A novel NF-κB-inhibitor peptide is a component in a skin care composition comprising the NF-κB-inhibitor and a dermatologically acceptable carrier. The composition may also include at least one additional skin care active. Additionally, the composition may include a peptide that acts as a TGF-β1 mimic. Means for treating mature, languished skin with compositions comprising the peptide are also provided.

公开(公告)号：US20160151270A1

公开(公告)日：2016-06-02

申请号：US15017635

申请日：2016-02-07

申请人： Geoffrey Brooks Consultants LLC

发明人： Geoffrey J. Brooks ,  Rajendra S. Bhatnagar ,  Andrew P. Banham

IPC分类号： A61K8/64 ,  A61Q19/08 ,  A61K8/49 ,  A61Q19/00 ,  A61K8/67 ,  A61K8/34

CPC分类号： A61K8/64 ,  A61K8/34 ,  A61K8/342 ,  A61K8/345 ,  A61K8/4953 ,  A61K8/498 ,  A61K8/675 ,  A61K2800/592 ,  A61Q7/00 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/08

摘要： The present invention relates to skin care compositions containing a small peptide mimic of TGF-β and to methods of using such compositions to manage the health and condition of skin and scalp. More preferably, the skin care compositions contain a safe and effective amount of a peptide mimic for TGF-β, derivatives of a peptide mimic for TGF-β, and mixtures thereof; a safe and effective amount of at least one skin care active; and a dermatologically acceptable carrier.

摘要翻译： 本发明涉及含有TGF-β的小肽模拟物的皮肤护理组合物。 以及使用这些组合物来管理皮肤和头皮的健康和状况的方法。 更优选地，皮肤护理组合物含有安全有效量的TGF-βb的模拟物的模拟物，以及TGF-β的模拟肽的衍生物及其混合物; 至少一种安全有效量的护肤活性物质; 和皮肤病学上可接受的载体。

公开(公告)号：US20170266258A1

公开(公告)日：2017-09-21

申请号：US15461320

申请日：2017-03-16

申请人： Geoffrey Brooks Consultants, LLC

发明人： Geoffrey J. Brooks ,  Rajendra S. Bhatnagar ,  Andrew P. Banham

IPC分类号： A61K38/18 ,  A61K9/00 ,  A61K38/08 ,  A61K8/64 ,  A61Q19/08

CPC分类号： A61K38/1841 ,  A61K8/64 ,  A61K9/0014 ,  A61K9/06 ,  A61K38/08 ,  A61K47/14 ,  A61Q19/08

摘要： A novel NF-κB-inhibitor peptide is a component in a skin care composition comprising the NF-κB-inhibitor and a dermatologically acceptable carrier. The composition may also include at least one additional skin care active. Additionally, the composition may include a peptide that acts as a TGF-β1 mimic. Means for treating mature, languished skin with compositions comprising the peptide are also provided.