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公开(公告)号:US20130137189A1
公开(公告)日:2013-05-30
申请号:US13745029
申请日:2013-01-18
申请人: Alan J. Polito , Richard M. Thayer , Robert K. DiNello , George H. Sierra , Dennis Nixon , Alan Phillips , Stuart Neubarth
发明人: Alan J. Polito , Richard M. Thayer , Robert K. DiNello , George H. Sierra , Dennis Nixon , Alan Phillips , Stuart Neubarth
IPC分类号: G01N27/22
CPC分类号: G01N27/227 , B01L3/5023 , G01N33/4875 , G01N33/54386 , G01N33/54393 , G01N33/558 , Y10S436/806 , Y10S436/807 , Y10T436/114998
摘要: An embodiment of the present invention provides a method for performing a lateral flow assay. The method includes depositing a sample on a test strip at an application region, detecting a first detection signal arising from the test strip in the first detection zone, and generating a baseline for the first measurement zone by interpolating between values of the detection signal outside of the first measurement zone and inside of the first detection zone. The method may include locating a beginning boundary and an ending boundary for the first measurement zone on the test strip. Additional detection zones having measurement zones may also be incorporated with the embodiment.
摘要翻译: 本发明的一个实施方案提供了一种用于进行侧流测定的方法。 该方法包括将样品沉积在应用区域的测试条上,检测在第一检测区域中由测试条产生的第一检测信号,以及通过在第一检测区域之外的检测信号的值之间进行内插来生成第一测量区域的基线 第一测量区域和第一检测区域内部。 该方法可以包括在测试条上定位用于第一测量区域的开始边界和结束边界。 具有测量区域的附加检测区域也可以结合实施例。
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公开(公告)号:US6136610A
公开(公告)日:2000-10-24
申请号:US199255
申请日:1998-11-23
申请人: Alan J. Polito , Richard M. Thayer , Robert K. DiNello , George H. Sierra , Dennis Nixon , Alan Phillips , Stuart Neubarth
发明人: Alan J. Polito , Richard M. Thayer , Robert K. DiNello , George H. Sierra , Dennis Nixon , Alan Phillips , Stuart Neubarth
IPC分类号: G01N33/543 , G01N33/558 , C12Q1/00 , C12N1/02 , C12Q1/70 , G01N33/53 , G01N35/02
CPC分类号: G01N27/227 , G01N33/54386 , G01N33/54393 , G01N33/558 , B01L3/5023 , G01N33/4875 , Y10S436/806 , Y10S436/807 , Y10T436/114998
摘要: An embodiment of the present invention provides a method for performing a lateral flow assay. The method includes depositing a sample on a test strip at an application region, detecting a first detection signal arising from the test strip in the first detection zone, and generating a baseline for the first measurement zone by interpolating between values of the detection signal outside of the first measurement zone and inside of the first detection zone. The method may include locating a beginning boundary and an ending boundary for the first measurement zone on the test strip. Additional detection zones having measurement zones may also be incorporated with the embodiment.
摘要翻译: 本发明的一个实施方案提供了一种用于进行侧流测定的方法。 该方法包括将样品沉积在应用区域的测试条上,检测在第一检测区域中由测试条产生的第一检测信号,以及通过在第一检测区域之外的检测信号的值之间进行内插来生成第一测量区域的基线 第一测量区域和第一检测区域内部。 该方法可以包括在测试条上定位用于第一测量区域的开始边界和结束边界。 具有测量区域的附加检测区域也可以结合实施例。
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公开(公告)号:US5160979A
公开(公告)日:1992-11-03
申请号:US652487
申请日:1991-02-08
申请人: Hiroyuki Ota , Takao Terada , Bernd G. Herpichboehm , George H. Sierra , Robert B. Summers , Thomas M. Watlington
发明人: Hiroyuki Ota , Takao Terada , Bernd G. Herpichboehm , George H. Sierra , Robert B. Summers , Thomas M. Watlington
CPC分类号: G01N21/293 , G01N2021/0181
摘要: An apparatus is provided for making color comparisons between a test sample and a plurality of color samples. The color samples are arranged on a circle on a rotatable member and are successively moved into position adjacent a test sample. When an operator determines that a color sample adjacent the test sample is closest in color to the test sample he operates a switch which causes a stored numerical value associated with that sample to be read out and displayed on a display device.
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公开(公告)号:US5120507A
公开(公告)日:1992-06-09
申请号:US272365
申请日:1988-11-17
申请人: Yoshihiko Sano , Shigeru Makita , Maury Zivitz , George H. Sierra
发明人: Yoshihiko Sano , Shigeru Makita , Maury Zivitz , George H. Sierra
CPC分类号: G01N21/8483 , G01N2021/478 , G01N21/4785
摘要: A reflection plate for a biochemical measuring instrument which is adapted to evaluate a biochemical value by obtaining a reflective property of a reflection surface of the reference reflection plate, obtaining a reflective property of test paper impregnated with biochemical sample and mounted on a test stick, and comparing the two reflective properties, wherein: the reflection surface of the reference reflection plate is depressed from the periphery thereof. Thereby, even though the test stick is required to be placed adjacent to the reflection surface to achieve a uniformity the optical arrangement in obtaining the two reflective properties, the contamination of the reflection surface from the sample can be prevented. Preferably, the reference reflection plate itself may be provided with a depression to defined the reflection surface at the bottom of this depression.
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公开(公告)号:USD318245S
公开(公告)日:1991-07-16
申请号:US293305
申请日:1989-01-04
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公开(公告)号:US5580790A
公开(公告)日:1996-12-03
申请号:US327349
申请日:1994-10-21
申请人: Robert Wall , George H. Sierra , Robert Evans , Sarah Bazydola , Alan Polito
发明人: Robert Wall , George H. Sierra , Robert Evans , Sarah Bazydola , Alan Polito
IPC分类号: B65D1/26 , B04B5/04 , B65D25/04 , G01N21/03 , G01N21/07 , G01N33/53 , G01N33/543 , G01N35/02
CPC分类号: B04B5/0421 , G01N21/07 , Y10T436/111666 , Y10T436/112499 , Y10T436/25375
摘要: Embodiments of the present invention feature a multilchambered cuvette having a first movement pattern and a second movement pattern, the first movement pattern comprises a stationary position and a rotation about a circular path. The second movement pattern comprises a rocking motion. The cuvette uses the first movement of fluid between chambers and a second movement pattern to effect mixing and incubation. The cuvette features a unitary housing having an opening over the first and second compartments to allow viewing and access.
摘要翻译: 本发明的实施例的特征在于具有第一运动模式和第二运动模式的多行比色皿,所述第一运动模式包括静止位置和围绕圆形路径的旋转。 第二运动模式包括摇摆运动。 比色皿使用腔室之间的流体的第一运动和第二运动模式来实现混合和孵育。 试管具有整体式壳体,其具有在第一和第二隔室上的开口,以允许观察和进入。
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公开(公告)号:US06528323B1
公开(公告)日:2003-03-04
申请号:US09332933
申请日:1999-06-14
IPC分类号: G01N3353
CPC分类号: G01N33/558 , G01N33/54386 , Y10S435/81 , Y10S435/97 , Y10S435/974 , Y10S435/975 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/81 , Y10S436/811 , Y10S436/817
摘要: A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to the sample addition zone, at least one of the test zones including a first analyte binding agent immobilized therein which is capable of binding to the analyte to be detected; and a terminal sample flow zone distal to the one or more test zones, the absorbent zone being positioned relative to the sample addition zone and having an absorption capacity relative to the other zones of the test strip such that a distal diffusion front of a sample added to the sample addition zone diffuses from the sample addition zone to a distal diffusion point within the terminal sample flow zone and then reverses direction and diffuses proximal relative to the one or more test zones.
摘要翻译: 提供了适于接收样品并检测其中的分析物的测试条。 测试条包括可以加入样品的样品添加区域; 靠近样品添加区的吸收区; 至少一个测试区域包括固定在其中的能够结合待检测分析物的第一分析物结合剂; 以及远离所述一个或多个测试区域的终端样品流动区域,所述吸收区域相对于所述样品添加区域定位,并且相对于所述测试条带的其它区域具有吸收能力,使得样品的远端扩散前沿 到样品添加区域从样品添加区域扩散到终端样品流动区域内的远端扩散点,然后反转方向并相对于一个或多个测试区域扩散近端。
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公开(公告)号:US5011290A
公开(公告)日:1991-04-30
申请号:US567699
申请日:1990-08-14
申请人: Takao Terada , Hiroyuki Ota , Shigeru Makita , Bernd G. Herpichboehm , George H. Sierra , Robert B. Summers , Thomas M. Watlington
发明人: Takao Terada , Hiroyuki Ota , Shigeru Makita , Bernd G. Herpichboehm , George H. Sierra , Robert B. Summers , Thomas M. Watlington
CPC分类号: G01N21/293 , G01N21/8483 , G01J3/522 , G01N2021/0181
摘要: A test sample color comparison device is disclosed which has a casing unit with an insertion slot for inserting a color test sample therein, and a display section for displaying the color test sample adjacent at least one of a plurality of reference color shades, as the reference color shades are successively moved into position adjacent the color test sample by a manipulation wheel. When an operator determines that a reference color shade adjacent the test sample corresponds in color to the color of the test sample, he pushes a switch to cause a readout of stored information corresponding to the reference color shade then adjacent the test sample. Readout of the stored information is based on a bit pattern set by a plurality of converter switches which are turned on and off in different patterns which correspond to the different color shades as the reference color shades are moved into position by the manipulation wheel. An uneven pattern code section moves in association with the manipulatable wheel and actuates the converter switches. A preferred uneven pattern code section is arranged so that all of the converter switches are actuated roughly equally during a full rotation of the manipulatable wheel, and so that only one of the converter switches is switched on or off during incremental movement of the manipulable wheel.
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公开(公告)号:US4871258A
公开(公告)日:1989-10-03
申请号:US187857
申请日:1988-04-29
CPC分类号: G01N21/8483 , G01N21/293 , G01J2003/466 , G01N2021/0181 , G01N2021/478 , G01N21/78
摘要: A colorimeter comprises a case, a liquid crystal display (LCD) mounted on the case, a color chart provided on the case to permit holding of a specimen to be compared in close proximity to the color chart, and switches for indicating which color on the color chart the color of the specimen most closely approximates. Each switch is located adjacent a color on the color chart, and the states of the switches drive the LCD to display a reading corresponding to the color on the color chart which most closely approximates the color of the specimen.
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公开(公告)号:US07229839B2
公开(公告)日:2007-06-12
申请号:US10346683
申请日:2003-01-17
IPC分类号: G01N33/53
CPC分类号: G01N33/558 , G01N33/54386 , Y10S435/81 , Y10S435/97 , Y10S435/974 , Y10S435/975 , Y10S436/805 , Y10S436/807 , Y10S436/808 , Y10S436/81 , Y10S436/811 , Y10S436/817
摘要: A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to the sample addition zone, at least one of the test zones including a first analyte binding agent immobilized therein which is capable of binding to the analyte to be detected; and a terminal sample flow zone distal to the one or more test zones, the absorbent zone being positioned relative to the sample addition zone and having an absorption capacity relative to the other zones of the test strip such that a distal diffusion front of a sample added to the sample addition zone diffuses from the sample addition zone to a distal diffusion point within the terminal sample flow zone and then reverses direction and diffuses proximal relative to the one or more test zones.
摘要翻译: 提供了适于接收样品并检测其中的分析物的测试条。 测试条包括可以加入样品的样品添加区域; 靠近样品添加区的吸收区; 至少一个测试区域包括固定在其中的能够结合待检测分析物的第一分析物结合剂; 以及远离所述一个或多个测试区域的终端样品流动区域,所述吸收区域相对于所述样品添加区域定位,并且相对于所述测试条带的其它区域具有吸收能力,使得样品的远端扩散前沿 到样品添加区域从样品添加区域扩散到终端样品流动区域内的远端扩散点,然后反转方向并相对于一个或多个测试区域扩散近端。
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