公开(公告)号：US08654170B2

公开(公告)日：2014-02-18

申请号：US13448592

申请日：2012-04-17

Applicant: Hidetoshi Yamashita

Inventor： Hidetoshi Yamashita

IPC: B41J2/435 ,  B41J2/385

CPC classification number: G03G15/043 ,  G03G15/5037 ,  G03G21/0094 ,  H01S5/0683

Abstract: An optical device includes a drive unit configured to drive a light source that outputs a laser beam; a detecting unit configured to detect the laser beam output from the light source; a converting unit configured to convert an output of the detecting unit into a value within a predetermined range; and a control unit configured to control the drive unit to switch a light quantity of the laser beam output from the light source from a first light quantity within an imaging light quantity range for forming an image to a second light quantity outside the imaging light quantity range, or vice versa. The converting unit converts an upper limit light quantity in the imaging light quantity range into a maximum value in the predetermined range, and converts a lower limit light quantity in the imaging light quantity range into a minimum value in the predetermined range.

Abstract translation: 光学装置包括被配置为驱动输出激光束的光源的驱动单元; 检测单元，被配置为检测从所述光源输出的激光束; 转换单元，被配置为将检测单元的输出转换成预定范围内的值; 以及控制单元，被配置为控制所述驱动单元将从所述光源输出的所述激光束的光量从用于形成图像的成像光量范围内的第一光量切换到所述成像光量范围外的第二光量 ， 或相反亦然。 转换单元将成像光量范围中的上限光量转换为预定范围内的最大值，并将成像光量范围中的下限光量转换为预定范围内的最小值。

公开(公告)号：US08417175B2

公开(公告)日：2013-04-09

申请号：US12185923

申请日：2008-08-05

Applicant: Hidetoshi Yamashita ,  Hisayuki Tomura ,  Kiyoharu Yoshioka ,  Michio Uchida ,  Tomonori Shida ,  Keisuke Mitsuhashi ,  Takuma Abe ,  Takao Nada

Inventor： Hidetoshi Yamashita ,  Hisayuki Tomura ,  Kiyoharu Yoshioka ,  Michio Uchida ,  Tomonori Shida ,  Keisuke Mitsuhashi ,  Takuma Abe ,  Takao Nada

IPC: G03G15/00 ,  G03G21/00

CPC classification number: G03G15/6573 ,  G03G2215/007 ,  G03G2215/00708

Abstract: A toner image formed on an image bearing member is transferred onto a recording material so as to overflow from an edge portion of the recording material, thereby enabling the toner image to be formed so as to extend to the edge portion of the recording material. To suppress the deposition of the toner in the edge portion of the recording material, a cleaning member for cleaning the edge portion of the recording material obtained after the fixing is provided. In order to make a trailing edge of the recording material come into contact with the cleaning member, the recording material which has passed through a fixing apparatus is temporarily switched back, thereby allowing the trailing edge portion of the recording material to collide with the cleaning member.

Abstract translation: 形成在图像承载部件上的调色剂图像被转印到记录材料上以便从记录材料的边缘部分溢出，从而使调色剂图像形成为延伸到记录材料的边缘部分。 为了抑制调色剂在记录材料的边缘部分中的沉积，提供了用于清洁在定影之后获得的记录材料的边缘部分的清洁部件。 为了使记录材料的后缘与清洁部件接触，已经通过定影装置的记录材料暂时转回，从而允许记录材料的后缘部分与清洁部件碰撞 。

公开(公告)号：US08294745B2

公开(公告)日：2012-10-23

申请号：US12859859

申请日：2010-08-20

Applicant: Hidetoshi Yamashita

Inventor： Hidetoshi Yamashita

IPC: B41J2/385 ,  B41J2/435 ,  H01S3/13

CPC classification number: B41J2/473

Abstract: An optical writing device includes a light source that emits multiple laser beams; a separating unit that separates each of the multiple laser beams into a monitor beam and a scanning beam; a photoelectric converting element 218 that outputs a monitor voltage depending on a quantity of the monitor beam; a memory that stores an initial correction value for correcting a set common current; and a microcontroller that calculates a reference current, which is produced by correcting the common current updated on the basis of the monitor voltages with the initial correction values, obtains corrected currents by correcting the common current with the calculated correction values, controls each quantity of the laser beam on the basis of the corrected currents, and determines that the light source is degraded if a ratio of the corrected current to the reference current is larger than a predetermined threshold value.

Abstract translation: 光学写入装置包括发射多个激光束的光源; 分离单元，其将所述多个激光束中的每一个分离成监视光束和扫描光束; 光电转换元件218，其根据监视光束的量输出监视电压; 存储器，用于存储用于校正设定的公共电流的初始校正值; 以及计算通过校正基于具有初始校正值的监视电压而更新的公共电流产生的参考电流的微控制器，通过用所计算的校正值校正公共电流来获得校正电流，控制每个量的 基于校正电流的激光束，并且如果校正电流与参考电流的比率大于预定阈值，则确定光源劣化。

公开(公告)号：US08094178B2

公开(公告)日：2012-01-10

申请号：US12125447

申请日：2008-05-22

Applicant: Hidetoshi Yamashita

Inventor： Hidetoshi Yamashita

IPC: B41J2/435 ,  B41J2/385 ,  G03G13/04

CPC classification number: G03G15/043 ,  G02B26/127 ,  G03G15/0435 ,  G03G2215/0404

Abstract: In an image forming apparatus, a separating unit separates each laser beam into a first laser beam used for measuring light intensity and a second laser beam used for scanning a photosensitive element, a photoelectric converting unit measures a light intensity of each of the first laser beams and outputs a voltage indicative of the light intensity. A control unit controls a light intensity of each of the laser beams based on a common drive current and a corresponding one of a current correction value, which is set by each of the laser beams to correct a light intensity of a corresponding one of the laser beams based on a corresponding one of the voltages output by the photoelectric converting unit.

Abstract translation: 在图像形成装置中，分离单元将每个激光束分离成用于测量光强度的第一激光束和用于扫描光敏元件的第二激光束，光电转换单元测量每个第一激光束的光强度 并输出表示光强度的电压。 控制单元基于公共驱动电流和由每个激光束设置的当前校正值中的相应一个来控制每个激光束的光强度，以校正相应激光束中的相应激光束的光强度 基于由光电转换单元输出的电压中的相应一个的光束。

公开(公告)号：US08080639B2

公开(公告)日：2011-12-20

申请号：US11981260

申请日：2007-10-31

Applicant: Kohei Miyazono ,  Peter ten Dijke ,  Petra Franzen ,  Hidetoshi Yamashita ,  Carl-Henrik Heldin

Inventor： Kohei Miyazono ,  Peter ten Dijke ,  Petra Franzen ,  Hidetoshi Yamashita ,  Carl-Henrik Heldin

IPC: C07K16/28 ,  C07K14/00 ,  A61K39/395

CPC classification number: C07K14/71 ,  A61K38/00

Abstract: A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-β-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.

Abstract translation: 已经鉴定了激活素样激酶的新受体家族。 新型蛋白质具有激活素/ TGF-β1型受体功能，并具有相应的诊断/治疗效用。 它们可以具有丝氨酸/苏氨酸激酶结构域，子域VIB中的DFKSRN或DLKSKN序列和/或亚域VIII中的GTKRYM序列。

公开(公告)号：US20110190250A1

公开(公告)日：2011-08-04

申请号：US13122467

申请日：2010-07-14

Applicant: Hidetoshi Yamashita ,  Teiko Yamamoto ,  Sakiko Goto ,  Sachi Abe ,  Eriko Kirii ,  Atsushi Okumura

Inventor： Hidetoshi Yamashita ,  Teiko Yamamoto ,  Sakiko Goto ,  Sachi Abe ,  Eriko Kirii ,  Atsushi Okumura

IPC: A61K31/56 ,  A61P27/02

CPC classification number: A61K9/107 ,  A61K9/0048 ,  A61K31/573 ,  A61K47/02 ,  A61K47/10 ,  A61K47/12 ,  A61K47/183 ,  A61K47/22 ,  A61K47/46

Abstract: The present invention aims to provide an eye drop for treating macular edema. The present invention provides an eye drop for treating macular edema, which contains difluprednate as an active ingredient. The eye drop can afford effects such as improvement of visual acuity and decreased foveal retinal thickness in macular edema.

Abstract translation: 本发明旨在提供一种治疗黄斑水肿的滴眼剂。 本发明提供一种治疗黄斑水肿的滴眼剂，其含有二氟泼尼酯作为活性成分。 眼药水可以提供视力改善和黄斑水肿中心凹视网膜厚度下降的效果。

公开(公告)号：US20110043594A1

公开(公告)日：2011-02-24

申请号：US12859859

申请日：2010-08-20

Applicant: Hidetoshi YAMASHITA

Inventor： Hidetoshi YAMASHITA

IPC: B41J2/435

CPC classification number: B41J2/473

Abstract: An optical writing device includes a light source that emits multiple laser beams; a separating unit that separates each of the multiple laser beams into a monitor beam and a scanning beam; a photoelectric converting element 218 that outputs a monitor voltage depending on a quantity of the monitor beam; a memory that stores an initial correction value for correcting a set common current; and a microcontroller that calculates a reference current, which is produced by correcting the common current updated on the basis of the monitor voltages with the initial correction values, obtains corrected currents by correcting the common current with the calculated correction values, controls each quantity of the laser beam on the basis of the corrected currents, and determines that the light source is degraded if a ratio of the corrected current to the reference current is larger than a predetermined threshold value.

Abstract translation: 光学写入装置包括发射多个激光束的光源; 分离单元，其将所述多个激光束中的每一个分离成监视光束和扫描光束; 光电转换元件218，其根据监视光束的量输出监视电压; 存储器，用于存储用于校正设定的公共电流的初始校正值; 以及计算通过校正基于具有初始校正值的监视电压而更新的公共电流产生的参考电流的微控制器，通过用所计算的校正值校正公共电流来获得校正电流，控制每个量的 基于校正电流的激光束，并且如果校正电流与参考电流的比率大于预定阈值，则确定光源劣化。

公开(公告)号：US20100150591A1

公开(公告)日：2010-06-17

申请号：US12561748

申请日：2009-09-17

Applicant: Hidetoshi YAMASHITA

Inventor： Hidetoshi YAMASHITA

IPC: G03G15/043 ,  G02B27/10

CPC classification number: B41J2/473 ,  G02B26/123 ,  G03G15/0435 ,  G03G15/326 ,  H04N1/40037 ,  H04N1/4005

Abstract: A first beam splitter splits each laser beam into a first beam and a second beam. A deflecting unit deflects a direction of the second beam. A second beam splitter splits the second beam into multiple split beams. A first photoelectric converting unit measures intensity of the first beam and outputs first voltage. A second photoelectric converting unit measures intensity of each split beam and outputs second voltage. A control unit updates a driving-current correction value using the first voltage and the second voltage, corrects a driving current, and controls intensity of the laser beam based on corrected driving current.

Abstract translation: 第一分束器将每个激光束分成第一光束和第二光束。 偏转单元偏转第二光束的方向。 第二分束器将第二光束分成多个分束。 第一光电转换单元测量第一光束的强度并输出第一电压。 第二光电转换单元测量每个分束的强度并输出第二电压。 控制单元使用第一电压和第二电压来更新驱动电流校正值，校正驱动电流，并且基于校正的驱动电流来控制激光束的强度。

公开(公告)号：US20090068744A1

公开(公告)日：2009-03-12

申请号：US12279432

申请日：2007-02-13

Applicant: Hidetoshi Yamashita ,  Teiko Yamamoto ,  Kouichi Nishitsuka ,  Yoshiko Kashiwagi ,  Naoki Tojo

Inventor： Hidetoshi Yamashita ,  Teiko Yamamoto ,  Kouichi Nishitsuka ,  Yoshiko Kashiwagi ,  Naoki Tojo

IPC: C12N5/10 ,  C12N15/85

CPC classification number: C12N5/0621 ,  C12N2501/135 ,  C12N2501/15 ,  C12N2501/165 ,  C12N2501/23 ,  C12N2501/25 ,  C12N2501/905 ,  C12N2503/00 ,  C12N2503/02 ,  C12N2510/04

Abstract: The present invention provides a vitreous cell line capable of expressing an exogenous immortalizing gene, and a production method thereof. Since the vitreous cell line of the present invention can produce a sufficient number of cells and has constant and continuous proliferative capacity, it can be advantageously utilized for the elucidation of the pathogenesis of retinal vitreous diseases, and the development of a drug for the prophylaxis and/or treatment of retinal vitreous diseases. Moreover, the cell line is not only highly useful for the biochemical-physiological studies of the vitreous body, and further for the study of cell differentiation mechanisms, but also possibly usable as a biological material of an artificial vitreous body.

Abstract translation: 本发明提供能够表达外源永生化基因的玻璃体细胞系及其制备方法。 由于本发明的玻璃体细胞系可以产生足够数量的细胞并且具有恒定和连续的增殖能力，因此可以有利地用于阐明视网膜玻璃体疾病的发病机理，并且开发用于预防和 /或治疗视网膜玻璃体疾病。 此外，细胞系不仅对玻璃体的生物化学生理学研究非常有用，进一步用于研究细胞分化机制，而且还可用作人造玻璃体的生物材料。

公开(公告)号：US20080309951A1

公开(公告)日：2008-12-18

申请号：US12137072

申请日：2008-06-11

Applicant: Yumiko KISHI ,  Toshio Ohide ,  Tatsuo Ohyama ,  Hidetoshi Yamashita ,  Nobuyoshi Kaima

Inventor： Yumiko KISHI ,  Toshio Ohide ,  Tatsuo Ohyama ,  Hidetoshi Yamashita ,  Nobuyoshi Kaima

IPC: G06K15/02

CPC classification number: H04N1/3935 ,  H04N1/58

Abstract: A novel image processing system includes a pixel position indicator and a pixel inserting unit. The pixel position indicator is configured to indicate insertion positions in the image data. The pixel inserting unit is configured to enlarge a size of the image data by inserting an additional pixel at each of the insertion positions and accordingly shifting the original pixels in a given direction. The additional pixel has a value lower than a given threshold. Each insertion position is at an approximate center of an area formed of pixels having values higher than the given threshold. A novel image forming apparatus incorporates such an image processing system and an electrophotographic system. The electrophotographic system is configured to form an image by irradiating a photoconductive surface with a laser beam according to the processed image data.

Abstract translation: 一种新颖的图像处理系统包括像素位置指示器和像素插入单元。 像素位置指示器被配置为指示图像数据中的插入位置。 像素插入单元被配置为通过在每个插入位置处插入附加像素来放大图像数据的大小，并且因此沿给定方向移位原始像素。 附加像素具有低于给定阈值的值。 每个插入位置在由具有高于给定阈值的像素形成的区域的大致中心处。 一种新颖的图像形成装置结合了这种图像处理系统和电子照相系统。 电照相系统被配置为根据处理的图像数据通过用激光束照射光电导表面来形成图像。