公开(公告)号：US07547819B2

公开(公告)日：2009-06-16

申请号：US10566157

申请日：2004-07-30

申请人： Shigeo Shibatani ,  Shuhei Misawa ,  Izumi Ihara ,  Hiroaki Kitazawa

发明人： Shigeo Shibatani ,  Shuhei Misawa ,  Izumi Ihara ,  Hiroaki Kitazawa

IPC分类号： C12N15/33 ,  C12N15/52 ,  C12N15/63 ,  C12N15/83 ,  A01H5/00

CPC分类号： C12P19/26 ,  A61K31/728 ,  C12N9/1051 ,  C12N15/8243

摘要： The invention relates to a method of producing hyaluronic acid including (1) a step of transforming a plant cell using an expression recombinant vector including (i) a DNA encoding hyaluronic acid synthase or (ii) a DNA encoding a polypeptide having an amino acid sequence having one or more amino acid deletions, substitutions, additions or insertions in an amino acid sequence of the hyaluronic acid synthase and having an activity of synthesizing the hyaluronic acid, (2) a step of growing a transformant obtained by transformation, and (3) a step of separating the hyaluronic acid produced by the transformant.

摘要翻译： 本发明涉及一种生产透明质酸的方法，包括（1）使用表达重组载体转化植物细胞的步骤，包括（i）编码透明质酸合酶的DNA或（ii）编码具有氨基酸序列的多肽的DNA 在透明质酸合酶的氨基酸序列中具有一个或多个氨基酸缺失，取代，添加或插入并具有合成透明质酸的活性，（2）生长通过转化获得的转化体的步骤，和（3） 分离由转化体产生的透明质酸的步骤。

公开(公告)号：US08003851B2

公开(公告)日：2011-08-23

申请号：US12063888

申请日：2006-08-10

申请人： Hiroaki Kitazawa ,  Shigeo Shibatani ,  Atsushi Sogabe

发明人： Hiroaki Kitazawa ,  Shigeo Shibatani ,  Atsushi Sogabe

IPC分类号： C12N15/82 ,  C12N15/09 ,  C12N15/00

CPC分类号： C12P19/26 ,  C12N15/8257

摘要： It is intended to provide by improving a known method of producing hyaluronic acid in a plant, a plant or a cultured plant cells which can produce hyaluronic acid at a lower cost and a further higher yield than before, a method of preparing the same, an expression vector for transformation, a method of producing hyaluronic acid using the plant or the cultured plant cells and the like. The method of producing hyaluronic acid comprising obtaining hyaluronic acid by co-expressing a protein with hyaluronic acid synthase activity and an exogenous protein with sugar-nucleotide synthase activity in a plant cell or a plant is provided.

摘要翻译： 本发明旨在通过改善可以以比以前更低的成本和更高的产量生产透明质酸的植物，植物或培养的植物细胞中制备透明质酸的已知方法，其制备方法， 用于转化的表达载体，使用植物或培养的植物细胞等产生透明质酸的方法。 提供了通过在植物细胞或植物中共同表达具有透明质酸合成酶活性的蛋白质和具有糖 - 核苷酸合成酶活性的外源蛋白质来获得透明质酸的方法。

公开(公告)号：US20110236512A1

公开(公告)日：2011-09-29

申请号：US13133184

申请日：2009-09-28

申请人： Hiroaki Kitazawa ,  Yoshihisa Kasukabe ,  Masaru Kitagawa

发明人： Hiroaki Kitazawa ,  Yoshihisa Kasukabe ,  Masaru Kitagawa

IPC分类号： A61K36/899 ,  A61K36/00 ,  A61K36/48 ,  A61P25/22

CPC分类号： A61K31/132 ,  A61K8/97 ,  A61K36/48 ,  A61Q19/08

摘要： [Object] An object of the present invention is to provide, for the purpose of preventing or suppressing stress at a cellular level, a composition containing a plant-derived polyamine-containing extract that has a stress-reducing action, an anti-stress action, a stress-suppressing action, a stress-preventing action, a stress-inhibiting action, a stress protective action, or the like. Another object of the present invention is to provide cosmetics, quasi drugs, medical supplies, sanitary goods, pharmaceuticals, foods, or drinks that each contain such a composition.[Solution] A stress-reducing agent including a plant-derived polyamine-containing extract serving as an active component is provided.

摘要翻译： 本发明的目的在于提供含有含有植物来源的含多胺的提取物的组合物，为了防止或抑制细胞水平的应力，其具有减轻作用，抗应激作用 ，应力抑制作用，应力防止作用，应力抑制作用，应力保护作用等。 本发明的另一个目的是提供各自含有这种组合物的化妆品，准药物，医疗用品，卫生用品，药品，食品或饮料。 [解决方案]提供了包含植物来源的含多胺的提取物作为活性成分的减压剂。

公开(公告)号：US20090260108A1

公开(公告)日：2009-10-15

申请号：US12063888

申请日：2006-08-10

申请人： Hiroaki Kitazawa ,  Shigeo Shibatani ,  Atsushi Sogabe

发明人： Hiroaki Kitazawa ,  Shigeo Shibatani ,  Atsushi Sogabe

IPC分类号： C12N15/82 ,  C12P19/04 ,  C12N5/04 ,  A01H5/00 ,  C12N15/00 ,  C08B37/00

CPC分类号： C12P19/26 ,  C12N15/8257

摘要： It is intended to provide by improving a known method of producing hyaluronic acid in a plant, a plant or a cultured plant cells which can produce hyaluronic acid at a lower cost and a further higher yield than before, a method of preparing the same, an expression vector for transformation, a method of producing hyaluronic acid using the plant or the cultured plant cells and the like. The method of producing hyaluronic acid comprising obtaining hyaluronic acid by co-expressing a protein with hyaluronic acid synthase activity and an exogenous protein with sugar-nucleotide synthase activity in a plant cell or a plant is provided.

摘要翻译： 本发明旨在通过改善可以以比以前更低的成本和更高的产量生产透明质酸的植物，植物或培养的植物细胞中制备透明质酸的已知方法，其制备方法， 用于转化的表达载体，使用植物或培养的植物细胞等产生透明质酸的方法。 提供了通过在植物细胞或植物中共同表达具有透明质酸合成酶活性的蛋白质和具有糖 - 核苷酸合成酶活性的外源蛋白质来获得透明质酸的方法。

公开(公告)号：US5717443A

公开(公告)日：1998-02-10

申请号：US766889

申请日：1996-12-13

申请人： Yasuhiro Numata ,  Haruo Uchida ,  Souhei Tanaka ,  Noribumi Koitabashi ,  Hiroaki Kitazawa ,  Hiromitsu Hirabayashi ,  Hiroshi Tajika ,  Hitoshi Sugimoto

发明人： Yasuhiro Numata ,  Haruo Uchida ,  Souhei Tanaka ,  Noribumi Koitabashi ,  Hiroaki Kitazawa ,  Hiromitsu Hirabayashi ,  Hiroshi Tajika ,  Hitoshi Sugimoto

IPC分类号： B41J2/165 ,  B41J23/02

CPC分类号： B41J23/025 ,  B41J2/1652

摘要： This invention relates to an ink jet recording apparatus with a support member for supporting an ink jet recording head for effecting recording by ink discharge onto a recording material, comprising: recording material transport means for transporting the recording material from a feeding position through a recording position to a discharge position; and recovery means for maintaining and restoring the ink discharge state of said ink jet recording head. The driving source for driving the recording material transport means or support member is also used for driving the recovery means, and, when the power supply to the apparatus is turned on, the initial operations of at least the recording material transport means and the recovery means are conducted utilizing a single sensor.

摘要翻译： 本发明涉及一种喷墨记录装置，具有用于支持喷墨记录头的支撑构件，用于通过喷墨记录在记录材料上进行记录，包括：记录材料传送装置，用于将记录材料从进给位置传送到记录位置 到排放位置; 以及用于维持和恢复所述喷墨记录头的排墨状态的恢复装置。 用于驱动记录材料传送装置或支撑构件的驱动源也用于驱动恢复装置，并且当打开装置的电源时，至少记录材料传送装置和恢复装置的初始操作 使用单个传感器进行。

公开(公告)号：US6086185A

公开(公告)日：2000-07-11

申请号：US143156

申请日：1993-10-29

申请人： Toshiharu Inui ,  Jiro Moriyama ,  Hiroaki Kitazawa ,  Yasuhiro Numata ,  Takayoshi Ishino ,  Isao Ebisawa ,  Hisao Yaegashi

发明人： Toshiharu Inui ,  Jiro Moriyama ,  Hiroaki Kitazawa ,  Yasuhiro Numata ,  Takayoshi Ishino ,  Isao Ebisawa ,  Hisao Yaegashi

IPC分类号： B41J2/21

CPC分类号： B41J2/2132

摘要： When the color printing is performed using a recording head arranged such that number of nozzles for discharging black ink is greater than the number of nozzles for discharging inks of other colors, the use frequency of some nozzles among all the nozzles for discharging the black ink is higher, so that image unevenness may arise when transferred to the black printing. The present invention relates to an ink jet recording method and an ink jet recording apparatus in which the image unevenness often seen in the black printing involving the use of more nozzles than other colors, and the blur of recorded image seen in the image having black images adjacent color images located are reduced.

摘要翻译： 当使用记录头执行彩色打印时，排列黑色墨水的喷嘴数量大于用于排出其他颜色的墨水的喷嘴的数量，所有用于排出黑色墨水的喷嘴中的一些喷嘴的使用频率是 更高，因此当转印到黑色印刷时可能会出现图像不均匀。 本发明涉及一种喷墨记录方法和喷墨记录装置，其中在黑色打印中经常看到的图像不均匀涉及使用比其它颜色更多的喷嘴，并且在具有黑色图像的图像中看到的记录图像的模糊 相邻的彩色图像被缩小。

公开(公告)号：US5835115A

公开(公告)日：1998-11-10

申请号：US520144

申请日：1995-08-28

申请人： Hiroaki Kitazawa

发明人： Hiroaki Kitazawa

IPC分类号： B41J2/05 ,  G06F3/12

CPC分类号： B41J2/0452 ,  B41J2/04541 ,  B41J2/04548 ,  B41J2/0456 ,  B41J2/0458

摘要： It is an object of the present invention to provide an image recording method and apparatus for performing stable image recording with a minimum power consumption. An AND gate performs an AND operation of a clock signal and a printing signal of binary logic in units of pixels, and a transistor is driven. At the driving timing, an induced electromotive force is generated in a choke coil having one end connected to a power supply line. A capacitor is charged with a forward current through a diode. On the other hand, the signal is shift-input to a shift register and latched by a latch circuit in synchronism with a signal. An output from the latch circuit is supplied to a gate circuit in synchronism with a signal to drive a transistor. A current from the capacitor is input to the transistor to heat a heater.

摘要翻译： 本发明的目的是提供一种以最小的功耗进行稳定的图像记录的图像记录方法和装置。 与门以像素为单位执行时钟信号和二进制逻辑的打印信号的AND运算，并驱动晶体管。 在驱动时刻，在一端与电源线连接的扼流线圈中产生感应电动势。 电容器通过二极管充电正向电流。 另一方面，该信号是移位输入到移位寄存器并由锁存电路与信号同步锁存。 来自锁存电路的输出与信号同步地提供给门电路以驱动晶体管。 将来自电容器的电流输入到晶体管以加热加热器。

公开(公告)号：US20060168690A1

公开(公告)日：2006-07-27

申请号：US10566157

申请日：2004-07-30

申请人： Shigeo Shibatani ,  Shuhei Misawa ,  Izumi Ihara ,  Hiroaki Kitazawa

发明人： Shigeo Shibatani ,  Shuhei Misawa ,  Izumi Ihara ,  Hiroaki Kitazawa

IPC分类号： C08B37/00 ,  C12N15/82 ,  A01H1/00 ,  C12N5/04

CPC分类号： C12P19/26 ,  A61K31/728 ,  C12N9/1051 ,  C12N15/8243

摘要： The invention relates to a method of producing hyaluronic acid comprising (1) a step of transforming a plant cell using an expression recombinant vector comprising (i) a DNA encoding hyaluronic acid synthase or (ii) a DNA encoding a polypeptide having an amino acid sequence having one or more amino acid deletions, substitutions, additions or insertions in an amino acid sequence of the hyaluronic acid synthase and having an activity of synthesizing the hyaluronic acid, (2) a step of growing a transformant obtained by transformation, and (3) a step of separating the hyaluronic acid produced by the transformant.

摘要翻译： 本发明涉及一种生产透明质酸的方法，其包括（1）使用表达重组载体转化植物细胞的步骤，所述表达重组载体包含（i）编码透明质酸合酶的DNA或（ii）编码具有氨基酸序列的多肽的DNA 在透明质酸合酶的氨基酸序列中具有一个或多个氨基酸缺失，取代，添加或插入并具有合成透明质酸的活性，（2）生长通过转化获得的转化体的步骤，和（3） 分离由转化体产生的透明质酸的步骤。

公开(公告)号：US6115148A

公开(公告)日：2000-09-05

申请号：US993054

申请日：1997-12-18

申请人： Kunio Imai ,  Masaya Kikuta ,  Hiroaki Kitazawa ,  Yuichi Hirai ,  Norio Shimura

发明人： Kunio Imai ,  Masaya Kikuta ,  Hiroaki Kitazawa ,  Yuichi Hirai ,  Norio Shimura

IPC分类号： H04N1/40 ,  H04N1/46

CPC分类号： H04N1/40 ,  H04N1/46

摘要： An image processor includes a video processing circuit which converts and processes a video signal. A first image processing circuit further processes the video signal processed by the video processing circuit, with emphasis on image gradation to generate image data matching the recording format of a recording apparatus. A second image processing circuit further processes the video signal processed by the video processing circuit, with emphasis on the sharpness of image contours to generate image data matching the recording format of the recording apparatus. A selecting circuit selects the first or second image processing circuit based on the type of video signal processed by the video processing circuit.

摘要翻译： 图像处理器包括转换和处理视频信号的视频处理电路。 第一图像处理电路进一步处理由视频处理电路处理的视频信号，重点在于图像灰度以产生与记录装置的记录格式相匹配的图像数据。 第二图像处理电路进一步处理由视频处理电路处理的视频信号，重点是图像轮廓的清晰度以产生与记录装置的记录格式相匹配的图像数据。 选择电路基于由视频处理电路处理的视频信号的类型来选择第一或第二图像处理电路。