摘要:
The present disclosure presents a unified system to phase a personal genome for downstream clinical interpretation. In an embodiment, an initial phasing is generated using public datasets, such as haplotypes from the 1000 Genomes Project, and a phasing toolkit. A local perturbation algorithm is applied to improve long range phasing. If available, a Mendelian inheritance pipeline is applied to identify phasing of novel and rare variants. These datasets are merged, followed by correction by any experimental data. This allows for full clinical interpretation of the role of a group of variants in a gene, whether inherited or de novo variants.
摘要:
An antistatic switch connected between a micro control unit and a power supply of an electronic device includes six terminals. A first terminal is left vacant and a third terminal is connected to the power supply. A second terminal is public access terminal connected to the micro control unit and selectively connected to the first terminal or the second terminal. The fourth terminal, the fifth terminal, and the sixth terminal are all grounded to remove the static electricity flowing to the electronic device.
摘要:
A protection circuit for protecting light-emitting diodes of a laser emitter is provided. The laser emitter includes a first LED for reading multimedia data stored in a first media and a second LED for reading multimedia data stored in a second media. Cathodes of the first LED and the second LED are grounded, and anodes of the first LED and the second LED are connected with soldering tin. The protection circuit includes a first protection element with a first breakdown voltage and a second protection element with a second breakdown voltage. One end of each of the first protection element and the second protection element is grounded. When the circuit is connected to the laser emitter, residual ends of the first protection element and the second protection element are respectively connected to the anodes of the first LED and the second LED.
摘要:
A protection circuit includes a relay, a reset switch, a voltage conversion circuit, and a rectifier circuit. The voltage conversion circuit is connected to an AC power supply via the reset switch, and converts a voltage of the AC power supply to a low AC voltage. The rectifier circuit converts the low AC voltage to a direct current voltage and powers a coil of the relay. At least one item of electronic apparatus is powered by the AC power supply via contacts of the relay or the reset switch. If the main power is lost, the relay releases, and the power connection must be re-established by pressing the reset switch after the AC power supply has been restored, thus energizing the relay to latch on the AC power supply.
摘要:
An electronic device with video in/out switching function using one port when connected with an external electronic apparatus includes a video switch circuit; an LCD; a processing unit, to decode and output video signals to the LCD; and an interface unit. In a video in mode, the video switch circuit connects the processing unit to the external electronic apparatus via the interface unit, thereby video signals from the external electronic apparatus are decoded and then output to the LCD. In a video out mode, the video switch circuit connects a video source to the external electronic via the interface unit, thereby video signals from the video source are output to the external electronic apparatus.
摘要:
A protection circuit for protecting light-emitting diodes of a laser emitter is provided. The laser emitter includes a first LED for reading multimedia data stored in a first media and a second LED for reading multimedia data stored in a second media. Cathodes of the first LED and the second LED are grounded, and anodes of the first LED and the second LED are connected with soldering tin. The protection circuit includes a first protection element with a first breakdown voltage and a second protection element with a second breakdown voltage. One end of each of the first protection element and the second protection element is grounded. When the circuit is connected to the laser emitter, residual ends of the first protection element and the second protection element are respectively connected to the anodes of the first LED and the second LED.
摘要:
A rangefinder for measuring a distance of an object includes a case, in which a refractor, a measuring light source, a light receiver, a receiving lens, a reference light source, and a reflector are provided. The measuring light source emits measuring light to the refractor, and the refractor refracts the measuring light to the object. The measuring light reflected by the object emits to the light receiver through the receiving lens. The reference light emits reference light to the reflector, and the reflector reflects the reference light to the light receiver. The refractor and the reflector may be turned for calibration.
摘要:
An electronic device includes an audio power amplifier used to output a left and a right channel audio signal, an earphone jack assembly, and a switching circuit automatically switching between a speaker mode and an earphone mode. The audio power amplifier includes a control pin enabling the audio power amplifier to be electrically connected to the speaker. The control pin activated at a low level and disabled at a high level. The switching circuit is capable of enabling the control pin to switch between the low level and the high level. The switching circuit includes a power supply, a first resistor, a second resistor, a third resistor, and a diode. The resistance of the third resistor far exceeds that of the first resistor.
摘要:
The present disclosure presents a unified system to phase a personal genome for downstream clinical interpretation. In an embodiment, an initial phasing is generated using public datasets, such as haplotypes from the 1000 Genomes Project, and a phasing toolkit. A local perturbation algorithm is applied to improve long range phasing. If available, a Mendelian inheritance pipeline is applied to identify phasing of novel and rare variants. These datasets are merged, followed by correction by any experimental data. This allows for full clinical interpretation of the role of a group of variants in a gene, whether inherited or de novo variants.
摘要:
A photo-sensor type touch device includes a screen, two light modules, a sensor, and a calculating unit. The screen has a displaying region to show images thereon. The light module emits linear invisible light to the displaying region. The invisible light is substantially perpendicular to a normal of the displaying region. The sensor senses a change of the invisible light on the displaying region when an object approaches the displaying region, and sends a signal out. The calculating unit is electrically connected to the sensor to receive the signal and calculate the signal to obtain a location of the object on the displaying region.