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1.发明公开公开(公告)号：US20240341950A1
公开(公告)日：2024-10-17
申请号：US18634470
申请日：2024-04-12
申请人： Michael Snyder
发明人： Michael Snyder
摘要： A temporary keratoprosthesis, a corneal transplant suturing jig, a temporary endoprosthesis, methods of using the same, and kits comprising the same. The temporary keratoprosthesis and corneal transplant comprise grooves into which sutures are located during ophthalmological surgery such that the sutures are prevented from migrating and/or obscuring a view into the eye during surgery. The temporary keratoprosthesis, corneal transplant suturing jig, and temporary endoprosthesis are employed alone or in unison to maintain intraocular pressure during surgery.
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2.发明公开公开(公告)号：US20240341949A1
公开(公告)日：2024-10-17
申请号：US18134849
申请日：2023-04-14
申请人： Michael Snyder
发明人： Michael Snyder
CPC分类号： A61F2/142 , A61F9/00727 , A61F2002/0081 , A61F2220/0008 , A61F2250/0059
摘要： A temporary keratoprosthesis, a corneal transplant suturing jig, a temporary endoprosthesis, methods of using the same, and kits comprising the same. The temporary keratoprosthesis and corneal transplant comprise grooves into which sutures are located during ophthalmological surgery such that the sutures are prevented from migrating and/or obscuring a view into the eye during surgery. The temporary keratoprosthesis, corneal transplant suturing jig, and temporary endoprosthesis are employed alone or in unison to maintain intraocular pressure during surgery.
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公开(公告)号：US20190053006A1
公开(公告)日：2019-02-14
申请号：US16040493
申请日：2018-07-19
申请人： Alan Michael Snyder
发明人： Alan Michael Snyder
摘要： Methods, computer readable storage medium, and systems for mobile devices to locate persons or places are described. In a feature, the invention is a method implemented in a server for providing beaconing sequences to the mobile devices for location sharing. In a feature, the invention is a server executing a method of locating a user using a beaconing mobile device. In a feature, the invention is a non-transitory computer readable medium on a server that encodes a program to execute a method on a first mobile device that determine directions and/or distance between the first mobile device and a second mobile device. In a feature, the invention is a server executing a method to remember a place on a mobile device.
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公开(公告)号：US10127346B2
公开(公告)日：2018-11-13
申请号：US13445923
申请日：2012-04-13
摘要： In an embodiment of the present invention, three novel human reference genome sequences were developed based on the most common population-specific DNA sequence (“major allele”). Methods were developed for their integration into interpretation pipelines for highthroughput whole genome sequencing.
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公开(公告)号：US10057719B2
公开(公告)日：2018-08-21
申请号：US15096258
申请日：2016-04-11
申请人： Alan Michael Snyder
发明人： Alan Michael Snyder
摘要： Methods, computer readable storage medium, and systems for mobile devices to locate persons or places are described. In a feature, the invention is a method implemented in a server for providing beaconing sequences to the mobile devices for location sharing. In a feature, the invention is a server executing a method of locating a user using a beaconing mobile device. In a feature, the invention is a non-transitory computer readable medium on a server that encodes a program to execute a method on a first mobile device that determine directions and/or distance between the first mobile device and a second mobile device. In a feature, the invention is a server executing a method to remember a place on a mobile device.
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公开(公告)号：US20150370963A9
公开(公告)日：2015-12-24
申请号：US13445923
申请日：2012-04-13
摘要： In an embodiment of the present invention, three novel human reference genome sequences were developed based on the most common population-specific DNA sequence (“major allele”). Methods were developed for their integration into interpretation pipelines for highthroughput whole genome sequencing.
摘要翻译： 在本发明的一个实施方案中，基于最常见的群体特异性DNA序列（“主要等位基因”）开发了三种新的人参照基因组序列。 开发了将其整合到用于高通量全基因组测序的解释管道中的方法。
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公开(公告)号：US09116155B2
公开(公告)日：2015-08-25
申请号：US12481970
申请日：2009-06-10
CPC分类号： G01N33/6887 , G01N2333/4712 , G01N2333/4737 , G01N2800/324 , G01N2800/60
摘要： The invention relates to methods for the early diagnosis of Acute Coronary Syndrome.
摘要翻译： 本发明涉及早期诊断急性冠状动脉综合征的方法。
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公开(公告)号：US20140235507A1
公开(公告)日：2014-08-21
申请号：US13840960
申请日：2013-03-15
申请人： Michael Snyder , Mark Reed , Heng Zhu , James Frank Klemic
发明人： Michael Snyder , Mark Reed , Heng Zhu , James Frank Klemic
IPC分类号： C12Q1/48
CPC分类号： C12Q1/485 , B01J19/0046 , B01J2219/00274 , B01J2219/00313 , B01J2219/00317 , B01J2219/00382 , B01J2219/00497 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00659 , B01J2219/00677 , B01J2219/00702 , B01J2219/00722 , B01J2219/00725 , B01L3/5085 , B82Y15/00 , B82Y30/00 , C40B40/06 , C40B40/10 , C40B60/14 , G01N33/5008 , G01N33/5041 , G01N33/543 , G01N33/54313 , G01N2500/00
摘要： The present invention relates to protein chips useful for the large-scale study of protein function where the chip contains densely packed reaction wells. The invention also relates to methods of using protein chips to assay simultaneously the presence, amount, and/or function of proteins present in a protein sample or on one protein chip, or to assay the presence, relative specificity, and binding affinity of each probe in a mixture of probes for each of the proteins on the chip. The invention also relates to methods of using the protein chips for high density and small volume chemical reactions. Also, the invention relates to polymers useful as protein chip substrates and methods of making protein chips. The invention further relates to compounds useful for the derivatization of protein chip substrates.
摘要翻译： 本发明涉及可用于大规模研究蛋白质功能的蛋白质芯片，其中芯片包含密集堆积的反应孔。 本发明还涉及使用蛋白质芯片同时测定存在于蛋白质样品中或在一个蛋白质芯片上的蛋白质的存在，量和/或功能的方法，或者测定每个探针的存在，相对特异性和结合亲和力 在芯片上的每种蛋白质的探针的混合物中。 本发明还涉及使用蛋白质芯片进行高密度和小体积化学反应的方法。 此外，本发明涉及可用作蛋白质芯片底物的聚合物和制备蛋白质芯片的方法。 本发明还涉及可用于蛋白质芯片底物衍生化的化合物。
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9.发明申请公开(公告)号：US20130093883A1
公开(公告)日：2013-04-18
申请号：US13274191
申请日：2011-10-14
申请人： Jiaping Wang , Baining Guo , Peiran Ren , John Michael Snyder , Xin Tong
发明人： Jiaping Wang , Baining Guo , Peiran Ren , John Michael Snyder , Xin Tong
IPC分类号： H04N7/18
CPC分类号： H04N1/00018 , G01N21/55 , H04N1/00013 , H04N1/00045 , H04N1/00087
摘要： A system for reflectance acquisition of a target includes a light source, an image capture device, and a reflectance reference chart. The reflectance reference chart is fixed relative to the target. The light source provides a uniform band of light across at least a dimension of the target. The image capture device is configured and positioned to encompass at least a portion of the target and at least a portion of the reflectance reference chart within a field-of-view of the image capture device. The image capture device captures a sequence of images of the target and the reflectance reference chart during a scan thereof. Reflectance responses are calculated for the pixels in the sequence of images. Reference reflectance response distribution functions are matched to the calculated reflectance responses, and an image of the target is reconstructed based at least in part on the matched reference reflectance response distribution functions.
摘要翻译： 用于目标的反射获取的系统包括光源，图像捕获装置和反射率参考图。 反射率参考图表相对于目标是固定的。 光源在目标的至少一维上提供均匀的光束。 图像捕获设备被配置和定位成在图像捕获设备的视野内包围目标的至少一部分和反射参考图的至少一部分。 图像捕获装置在其扫描期间捕获目标的图像序列和反射率参考图。 针对图像序列中的像素计算反射响应。 参考反射响应分布函数与所计算的反射率响应匹配，并且至少部分地基于匹配的参考反射响应分布函数来重建目标的图像。
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公开(公告)号：US08404269B2
公开(公告)日：2013-03-26
申请号：US10821745
申请日：2004-04-09
申请人： Michael Snyder , Eric M. Dobrusin
发明人： Michael Snyder , Eric M. Dobrusin
CPC分类号： A61K9/0024 , A61K9/0051
摘要： A surgical device and method of making and using the same for implantation in a body of a mammal. One preferred device is prepared to include an elongated member. A region includes a pharmaceutical agent and a bioerodible material, a biodegradable material a bioavailable material or a mixture thereof.
摘要翻译： 一种外科手术装置及其制造方法以及用于植入哺乳动物体内的方法。 制备一种优选的装置包括细长构件。 区域包括药剂和生物可侵蚀材料，生物降解材料，生物可利用材料或其混合物。
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