USE OF COMPOUNDS ISOLATED FROM MORUS BARK
    6.
    发明申请
    USE OF COMPOUNDS ISOLATED FROM MORUS BARK 审中-公开
    使用从MORUS BARK分离的化合物

    公开(公告)号:US20140018552A1

    公开(公告)日:2014-01-16

    申请号:US14007603

    申请日:2012-03-26

    IPC分类号: A61K31/352 A23L1/30 A61K31/05

    摘要: The present invention provides an AGE inhibitor and a health functional food for inhibiting an occurrence of diabetic complications. Particularly, the present invention comprises a compound selected from the group consisting of mulberrofuran G, mulberrofuran K, kuwanon G, kuwanon Z, oxyresveratrol, 2′,4′,5,7-tetrahydroxyflavanone, morusignin L and dihydromorin isolated from Morus Bark as an active ingredient. The compounds disclosed above inhibit the production of AGE which is a causative substance of diabetic complications. Thus, the compounds could be used as an AGE inhibitor and a health functional food for inhibiting diabetic nephropathy, diabetic retinopathy and diabetic neuropathy.

    摘要翻译: 本发明提供了AGE抑制剂和用于抑制糖尿病并发症发生的健康功能性食品。 特别地,本发明包括选自以下物质中的化合物:由呋喃孢菌G,呋喃布鲁氏菌K,kuwanon G,kuwanon Z,氧基维甲酸,2',4',5,7-四羟基黄酮,morusignin L和从Morus Bark分离的二氢肌醇 有效成分。 上述公开的化合物抑制作为糖尿病并发症的病因的AGE的产生。 因此,该化合物可用作AGE抑制剂和用于抑制糖尿病性肾病,糖尿病性视网膜病变和糖尿病性神经病变的健康功能食品。