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    PERCUTANEOUS ABSORPTION PREPARATION CONTAINING RIVASTIGMINE
    1.
    发明申请
    PERCUTANEOUS ABSORPTION PREPARATION CONTAINING RIVASTIGMINE 审中-公开
    包含RIVASTIGMINE的PERCUTANEOUSO吸收制剂

    公开(公告)号：US20130267916A1

    公开(公告)日：2013-10-10

    申请号：US13994788

    申请日：2011-12-22

    申请人： Hyun-Suk Yu ,  Young-Moo Lee ,  Hyun-Woo Kim ,  Hee-Sook Kim

    发明人： Hyun-Suk Yu ,  Young-Moo Lee ,  Hyun-Woo Kim ,  Hee-Sook Kim

    IPC分类号： A61K9/70 ,  A61K31/27

    CPC分类号： A61K9/703 ,  A61K9/7053 ,  A61K31/27

    摘要： Disclosed is a percutaneous absorption preparation for treatment of dementia that comprises rivastigmine or its pharmaceutically acceptable salt as an active ingredient, a styrene-isoprene-styrene block copolymer, a tackifier resin, and a plasticizer, which preparation contains a small amount of rivastigmine but allows a sufficient amount of the active ingredient penetrated into the skin to achieve an effective treatment of dementia.

    摘要翻译： 公开了一种用于治疗痴呆的经皮吸收制剂，其包含作为活性成分的利伐斯的明或其药学上可接受的盐，苯乙烯 - 异戊二烯 - 苯乙烯嵌段共聚物，增粘树脂和增塑剂，该制剂含有少量的利凡斯的明但允许 足够量的活性成分渗入皮肤以实现痴呆的有效治疗。

    Dual adhesive transdermal drug delivery system
    3.
    发明授权
    Dual adhesive transdermal drug delivery system 有权
    双胶透皮给药系统

    公开(公告)号：US06791003B1

    公开(公告)日：2004-09-14

    申请号：US10110843

    申请日：2002-08-09

    申请人： Young Kweon Choi ,  Hyun Suk Yu ,  Hye Jeong Yoon ,  Ho Chin Kim

    发明人： Young Kweon Choi ,  Hyun Suk Yu ,  Hye Jeong Yoon ,  Ho Chin Kim

    IPC分类号： A61F1300

    CPC分类号： A61K9/703 ,  A61K9/7061 ,  A61K9/7069 ,  A61K9/7084 ,  A61K9/7092

    摘要： A dual drug containing adhesive transdermal drug delivery system comprising: a support layer, a first drug containing adhesive layer and a second drug containing adhesive layer each of said layers having a proximal and distal surface wherein each layer is positioned adjacent to the other with each layer having its distal surface laminated to said support layer, and a peelable backing layer positioned over and laminated to the proximal surface of said first and second adhesive layers is disclosed.

    摘要翻译： 一种双重药物的粘合剂透皮药物递送系统，包括：支撑层，含有第一药物的粘合剂层和第二药物含有粘合剂层，每个所述层具有近端表面和远端表面，其中每层与每层相邻地定位 其远侧表面层压到所述支撑层，以及位于所述第一和第二粘合剂层的近侧表面上方并层压到所述第一和第二粘合剂层的近侧表面上的可剥离背衬层。

    Patch for tooth whitening
    4.
    发明授权
    Patch for tooth whitening 有权
    修补牙齿美白

    公开(公告)号：US07323161B2

    公开(公告)日：2008-01-29

    申请号：US10729648

    申请日：2003-12-05

    申请人： Young Kweon Choi ,  Hyun Suk Yu ,  Jae Soon Ahn ,  Hee Sook Kim ,  Hyun Woo Kim

    发明人： Young Kweon Choi ,  Hyun Suk Yu ,  Jae Soon Ahn ,  Hee Sook Kim ,  Hyun Woo Kim

    IPC分类号： A61K8/00 ,  A61Q11/00 ,  A61F13/00

    CPC分类号： A61K8/0208 ,  A61K8/22 ,  A61K8/731 ,  A61K8/8147 ,  A61K8/8176 ,  A61Q11/00

    摘要： The patch for tooth whitening of the present invention includes a tooth-adhering layer (1) containing erodible polymer complexes formed by hydrogen bonding of a polymer with a carboxyl group (—COOH) and a polymer with a carbonyl group (—C═O) or ether group (—O—) and a tooth whitening agent; and an erosion rate-controlling layer (2) containing a mixture of a hydrophilic polymer and a film-forming polymer, wherein the patch is in a film form and is characterized by being eroded until extinguished after releasing the tooth whitening agent. When applied to the teeth, the patch releases a peroxide tooth-whitening agent while being hydrated by water in the mouth during a prescribed period, and thereafter, eroded until extinguished, thereby not requiring an additional detaching work from the teeth. Therefore, the patch is convenient in use and greatly reduces an obstruction sensation. Moreover, the patch has an excellent whitening effect.

    摘要翻译： 本发明的牙齿美白用贴剂包括：通过聚合物与羧基（-COOH）的氢键和具有羰基（-CO）或醚的聚合物（-CO）形成的含有可侵蚀聚合物络合物的牙齿粘附层（1） 基团（-O-）和牙齿增白剂; 以及包含亲水性聚合物和成膜聚合物的混合物的侵蚀速率控制层（2），其中所述贴剂是膜形式，其特征在于在释放牙齿增白剂后被侵蚀直到熄灭。 当施用于牙齿时，补片在规定的时间段内释放过氧化物牙齿增白剂，同时在口中水分水合，然后腐蚀直到熄灭，从而不需要从牙齿进一步的分离工作。 因此，贴片使用方便，大大降低了障碍感。 此外，贴剂具有优异的美白效果。