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公开(公告)号：US09303261B2
公开(公告)日：2016-04-05
申请号：US14126505
申请日：2012-06-13
申请人： Kyu Han Kim , Hyun Jung Choi , Bum Ho Bin , Tae Ryong Lee
发明人： Kyu Han Kim , Hyun Jung Choi , Bum Ho Bin , Tae Ryong Lee
IPC分类号： C12N15/113 , A61K31/7105 , A61K8/00 , A61K8/60 , A61Q5/10 , G01N33/50
CPC分类号： C12N15/1137 , A61K8/606 , A61K31/7105 , A61K2800/78 , A61K2800/782 , A61Q5/10 , C12N15/113 , C12N2310/113 , C12N2310/141 , G01N33/5023
摘要： Disclosed is a composition for a whitening effect or for the prevention of gray hair, which includes antisense nucleic acid molecules of SEQ ID NO: 2, wherein the composition has an miRNA of SEQ ID NO: 1 or a base sequence complementary thereto. Also disclosed is a method for controlling chromogenesis in test materials and for screening for expression control materials of chromogenic genes. The composition and the screening methodcan be used for the whitening effect or for the prevention of gray hair.
摘要翻译： 公开了一种用于美白效果或防止灰白毛发的组合物，其包括SEQ ID NO：2的反义核酸分子，其中所述组合物具有SEQ ID NO：1的miRNA或其互补的碱基序列。 还公开了一种用于控制测试材料中的发色和筛选显色基因的表达控制材料的方法。 组合物和筛选方法可用于美白效果或用于防止灰白色毛发。
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公开(公告)号：US20130329766A1
公开(公告)日：2013-12-12
申请号：US14000543
申请日：2012-02-15
申请人： Eui Dong Son , Hyeon Chung Kim , Ji Hyun Kim , Hyun Jung Choi , Gae Won Nam , Tae Ryong Lee , Jin Ho Chung , Seon Pil Jin
发明人： Eui Dong Son , Hyeon Chung Kim , Ji Hyun Kim , Hyun Jung Choi , Gae Won Nam , Tae Ryong Lee , Jin Ho Chung , Seon Pil Jin
IPC分类号： G01K11/00
摘要： The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.
摘要翻译： 本发明涉及一种计算热保护因子的方法，其中该方法包括以下步骤：将热量施加到涂覆有热保护材料的第一区域和未涂覆有热保护材料的第二区域; 测量第一区域和第二区域的各自的饱和温度; 通过将对应于第一区域的热量的能量除以第一区域的饱和温度来计算第一能量; 通过将对应于第二区域的热量的能量除以第二区域的饱和温度来计算第二能量; 以及通过将第一能量除以第二能量或将第一能量与第二能量之间的差除以第一能量来计算热保护材料的热保护因子。
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3.发明申请EXTERNAL COMPOSITION FOR SKIN CONTAINING MANASSANTIN B AS ACTIVE INGREDIENT AND THE USE THEREOF FOR SKIN WHITENING 审中-公开含有作为活性成分的马尼松丁B的皮肤外用组合物及其用于皮肤白化的用途公开(公告)号：US20120301413A1
公开(公告)日：2012-11-29
申请号：US13568975
申请日：2012-08-07
申请人： Hui Kyoung CHANG , DaeGun KIM , Myeong Hoon YEOM , Hyun Jung CHOI , Kyung Mi JOO , Jae Sung HWANG , Soo Mi AHN
发明人： Hui Kyoung CHANG , DaeGun KIM , Myeong Hoon YEOM , Hyun Jung CHOI , Kyung Mi JOO , Jae Sung HWANG , Soo Mi AHN
CPC分类号： A61K8/4973 , A61K31/343 , A61Q19/02
摘要： Disclosed herein are an external composition for skin, which contains, as an active ingredient, manassantin B extracted from Saururus chinensis Baill, and the use thereof for skin whitening. More particularly, disclosed are an external composition for skin, which contains, as an active ingredient, manassantin B, which inhibits the transfer of melanosomes, thus providing a skin-whitening effect without influencing the melanin synthesis function of the melanocytes, as well as the use thereof for skin whitening.
摘要翻译： 本发明公开了一种皮肤外用组合物，其含有作为活性成分的从中华黄ensis提取的马桑丁B及其用于皮肤美白的用途。 更具体地，公开了一种皮肤外用组合物，其含有抑制黑素体转移的马桑丁汀B作为活性成分，从而提供皮肤美白效果而不影响黑素细胞的黑色素合成功能，以及 其用于皮肤美白。
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4.发明授权3,4,5-trimethoxy phenyl-based ester compound and preparation method thereof and whitening cosmetic composition containing the same 有权3,4,5-三甲氧基苯基酯化合物及其制备方法和含有该化合物的美白化妆品组合物公开(公告)号：US07517911B2
公开(公告)日：2009-04-14
申请号：US10490280
申请日：2002-09-23
申请人： Ho-Sik Rho , Jae-Sung Hwang , Hyun-Jung Choi , Hyun-Jung Shin , Bae-Hwan Kim , Eun-Young Lee , Byeong-Gon Lee , Duck-Hee Kim
发明人： Ho-Sik Rho , Jae-Sung Hwang , Hyun-Jung Choi , Hyun-Jung Shin , Bae-Hwan Kim , Eun-Young Lee , Byeong-Gon Lee , Duck-Hee Kim
CPC分类号： A61Q19/02 , A61K8/37 , C07C69/734
摘要： The present invention relates to ester compounds derived from 3,4,5-trimethoxy phenyl acetate, 3,4,5-trimethoxy cinnamate or 3,4,5-trimethoxy hydrocinnamate that are represented by Formula (I), wherein R1 is CH2—, —CH═CH— or CH2—CH2, R2 is thymyl or carvacryl, to methods for preparing them, and to a whitening cosmetic composition containing the ester compounds. Because the ester compounds of the present invention inhibit the generation of melanin, the cosmetic composition can improve the skin pigmentation and can be used for whitening cosmetics.
摘要翻译： 本发明涉及由式（I）表示的3,4,5-三甲氧基苯基乙酸酯，3,4,5-三甲氧基肉桂酸酯或3,4,5-三甲氧基氢化肉桂酸酯衍生的酯化合物，其中R1是CH2- ，-CH-CH-或CH 2 -CH 2，R 2是胸腺酰基或carvacryl，制备它们的方法，和含有酯化合物的美白化妆品组合物。 因为本发明的酯化合物抑制黑色素的产生，所以化妆品组合物可以改善皮肤色素沉积，并可用于美白化妆品。
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公开(公告)号：US09867772B2
公开(公告)日：2018-01-16
申请号：US14506128
申请日：2014-10-03
申请人： Eui Dong Son , Dae Jin Min , Hui Kyoung Chang , Hyun Jung Choi , Seong A Cho , Ji Hyun Kim , Tae Ryong Lee
发明人： Eui Dong Son , Dae Jin Min , Hui Kyoung Chang , Hyun Jung Choi , Seong A Cho , Ji Hyun Kim , Tae Ryong Lee
摘要： Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.
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公开(公告)号：US20140134636A1
公开(公告)日：2014-05-15
申请号：US14126505
申请日：2012-06-13
申请人： Kyu Han Kim , Hyun Jung Choi , Bum Ho Bin , Tae Ryong Lee
发明人： Kyu Han Kim , Hyun Jung Choi , Bum Ho Bin , Tae Ryong Lee
IPC分类号： C12N15/113 , G01N33/50
CPC分类号： C12N15/1137 , A61K8/606 , A61K31/7105 , A61K2800/78 , A61K2800/782 , A61Q5/10 , C12N15/113 , C12N2310/113 , C12N2310/141 , G01N33/5023
摘要： Disclosed is a composition for a whitening effect or for the prevention of gray hair, which includes antisense nucleic acid molecules of SEQ ID NO: 2, wherein the composition has an miRNA of SEQ ID NO: 1 or a base sequence complementary thereto. Also disclosed is a method for controlling chromogenesis in test materials and for screening for expression control materials of chromogenic genes. The composition and the screening method can be used for the whitening effect or for the prevention of gray hair.
摘要翻译： 公开了一种用于美白效果或防止灰白毛发的组合物，其包括SEQ ID NO：2的反义核酸分子，其中所述组合物具有SEQ ID NO：1的miRNA或其互补的碱基序列。 还公开了一种用于控制测试材料中的发色和筛选显色基因的表达控制材料的方法。 组合物和筛选方法可用于美白效果或防止灰白色毛发。
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7.发明申请3,4,5-Trimethoxy phenyl-based ester compound and preparation method thereof and whitening cosmetic composition containing the same 有权3,4,5-三甲氧基苯基酯化合物及其制备方法和含有该化合物的美白化妆品组合物公开(公告)号：US20060167093A1
公开(公告)日：2006-07-27
申请号：US10490280
申请日：2002-09-23
申请人： Ho-Sik Rho , Jae-Sung Hwang , Hyun-Jung Choi , Hyun-Jung Shin , Bae-Hwan Kim , Eun-Young Lee , Byeong-Gon Lee , Duck-Hee Kim
发明人： Ho-Sik Rho , Jae-Sung Hwang , Hyun-Jung Choi , Hyun-Jung Shin , Bae-Hwan Kim , Eun-Young Lee , Byeong-Gon Lee , Duck-Hee Kim
IPC分类号： A61K31/235 , C07C69/88
CPC分类号： A61Q19/02 , A61K8/37 , C07C69/734
摘要： The present invention relates to ester compounds derived from 3,4,5-trimethoxy phenyl acetate, 3,4,5-trimethoxy cinnamate or 3,4,5-trimethoxy hydrocinnamate that are represented by Formula (I), wherein R1 is CH2—, —CH═CH— or CH2—CH2, R2 is thymyl or carvacryl, to methods for preparing them, and to a whitening cosmetic composition containing the ester compounds. Because the ester compounds of the present invention inhibit the generation of melanin, the cosmetic composition can improve the skin pigmentation and can be used for whitening cosmetics.
摘要翻译： 本发明涉及由式（I）表示的3,4,5-三甲氧基苯基乙酸酯，3,4,5-三甲氧基肉桂酸酯或3,4,5-三甲氧基氢化肉桂酸酯的酯化合物，其中R 1， 1是CH 2 - ， - CH-CH-或CH 2 -CH 2，R 2， SUB>是胸腺酰基或carvacryl，其制备方法和含有酯化合物的美白化妆品组合物。 因为本发明的酯化合物抑制黑色素的产生，所以化妆品组合物可以改善皮肤色素沉积，并可用于美白化妆品。
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公开(公告)号：US20130171274A1
公开(公告)日：2013-07-04
申请号：US13819763
申请日：2011-08-30
申请人： Eui Dong Son , Dae Jin Min , Hui Kyoung Chang , Hyun Jung Choi , Seong A. Cho , Ji Hyun Kim , Tae Ryong Lee
发明人： Eui Dong Son , Dae Jin Min , Hui Kyoung Chang , Hyun Jung Choi , Seong A. Cho , Ji Hyun Kim , Tae Ryong Lee
CPC分类号： A61K8/97 , A61K8/14 , A61K8/64 , A61K8/9789 , A61K2800/56 , A61Q19/00 , A61Q19/08
摘要： Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.
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公开(公告)号：US20150044265A1
公开(公告)日：2015-02-12
申请号：US14506128
申请日：2014-10-03
申请人： Eui Dong SON , Dae Jin MIN , Hui Kyoung CHANG , Hyun Jung CHOI , Seong A CHO , Ji Hyun KIM , Tae Ryong LEE
发明人： Eui Dong SON , Dae Jin MIN , Hui Kyoung CHANG , Hyun Jung CHOI , Seong A CHO , Ji Hyun KIM , Tae Ryong LEE
摘要： Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.
摘要翻译： 本发明提供一种用于改善皮肤弹性的化妆品组合物，其中含有叶黄芩提取物和抗衰老肽作为活性成分稳定的聚合物。 本公开的化妆品组合物在改善皮肤皱纹，恢复皮肤弹性和增加皮肤含水量方面是有效的，因此对于改善皮肤弹性是有效的。
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10.发明申请External Composition For Skin Containing Manassantin B as Active Ingredient and the Use Thereof For Skin Whitening 审中-公开含有Manassantin B作为活性成分的皮肤外用组合物及其用于皮肤美白的用途公开(公告)号：US20100256228A1
公开(公告)日：2010-10-07
申请号：US12515151
申请日：2007-11-02
申请人： Hui Kyoung Chang , Dae Gun Kim , Myeong Hoon Yeom , Hyun Jung Choi , Kyung Mi Joo , Jae Sung Hwang , Soo Mi Ahn
发明人： Hui Kyoung Chang , Dae Gun Kim , Myeong Hoon Yeom , Hyun Jung Choi , Kyung Mi Joo , Jae Sung Hwang , Soo Mi Ahn
IPC分类号： A61K8/49 , C07D407/12 , A61Q19/02
CPC分类号： A61K8/4973 , A61K31/343 , A61Q19/02
摘要： Disclosed herein are an external composition for skin, which contains, as an active ingredient, manassantin B extracted from Saururus chinensis Baill, and the use thereof for skin whitening. More particularly, disclosed are an external composition for skin, which contains, as an active ingredient, manassantin B, which inhibits the transfer of melanosomes, thus providing a skin-whitening effect without influencing the melanin synthesis function of the melanocytes, ad well as the use thereof for skin whitening.
摘要翻译： 本发明公开了一种皮肤外用组合物，其含有作为活性成分的从中华黄ensis提取的马桑丁B及其用于皮肤美白的用途。 更具体地，公开了一种皮肤外用组合物，其包含作为活性成分的抑制黑素体转移的马桑丁汀B，从而提供皮肤美白效果而不影响黑素细胞的黑色素合成功能，以及作为 其用于皮肤美白。
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