公开(公告)号：US09801780B2

公开(公告)日：2017-10-31

申请号：US14661988

申请日：2015-03-18

申请人： Infarct Reduction Technologies Inc.

发明人： Boris Leschinsky

IPC分类号： A61B5/022 ,  A61H9/00 ,  A61B17/135 ,  A61B17/12 ,  A61B17/00

CPC分类号： A61H9/0092 ,  A61B5/02208 ,  A61B5/02225 ,  A61B5/02233 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/135 ,  A61B17/1355 ,  A61B2017/00199 ,  A61H2201/5035 ,  A61H2201/5038 ,  A61H2201/5071 ,  A61H2205/06 ,  A61H2205/10 ,  A61H2230/30

摘要： Single- or dual-bladder devices for automated delivery of remote ischemic conditioning treatment via partial limb occlusion involve various methods of operating the cuff in which partial or full limb occlusion is achieved during the periods of cuff inflation. Achieving clinical benefits of remote ischemic conditioning without extended cessation of limb blood flow are advantageous due to lower required cuff pressure and reduced risk of clot formation in the limb vasculature.

公开(公告)号：US20130211269A1

公开(公告)日：2013-08-15

申请号：US13836418

申请日：2013-03-15

申请人： Infarct Reduction Technologies Inc.

发明人： Boris Leschinsky

IPC分类号： A61B17/135 ,  A61B5/022

CPC分类号： A61B17/1355 ,  A61B5/0002 ,  A61B5/02225 ,  A61B5/02233 ,  A61B5/0225 ,  A61B5/1112

摘要： Methods for adaptive cuff inflation for the purposes of occluding a limb of a subject include inflating a cuff to a pressure at or above limb occlusion pressure and periodically deflating the cuff to detect amplitude of oscillometric oscillations reaching or exceeding a predetermined threshold, whereby indicating that the cuff pressure has reached an updated systolic blood pressure. Selecting the cuff to be wide enough to define limb occlusion pressure at or below the systolic blood pressure assures that this maneuver does not compromise cessation of blood flow to the limb. Devices are disclosed configured to operate in at least two of the following three operating modes: a tourniquet mode, a remote conditioning mode and a blood pressure monitoring mode.

摘要翻译： 用于闭塞受试者肢体的适应性袖带充气的方法包括将袖带充气至肢体阻塞压力或高于肢体阻塞压力，并周期性地缩小袖带以检测达到或超过预定阈值的示波振荡的幅度，从而指示 袖带压力已经达到更新的收缩压。 选择足够宽的袖口以确定收缩压或低于收缩压的肢体闭塞压力，确保该手术不会损害肢体停止血液流动。 公开了被配置为以以下三种操作模式中的至少两种操作的装置：止血带模式，远程调节模式和血压监测模式。

公开(公告)号：US20150190301A1

公开(公告)日：2015-07-09

申请号：US14661988

申请日：2015-03-18

申请人： Infarct Reduction Technologies Inc.

发明人： Boris Leschinsky

IPC分类号： A61H9/00

CPC分类号： A61H9/0092 ,  A61B5/02208 ,  A61B5/02225 ,  A61B5/02233 ,  A61B17/12109 ,  A61B17/12136 ,  A61B17/135 ,  A61B17/1355 ,  A61B2017/00199 ,  A61H2201/5035 ,  A61H2201/5038 ,  A61H2201/5071 ,  A61H2205/06 ,  A61H2205/10 ,  A61H2230/30

摘要： Single- or dual-bladder devices for automated delivery of remote ischemic conditioning treatment via partial limb occlusion involve various methods of operating the cuff in which partial or full limb occlusion is achieved during the periods of cuff inflation. Achieving clinical benefits of remote ischemic conditioning without extended cessation of limb blood flow are advantageous due to lower required cuff pressure and reduced risk of clot formation in the limb vasculature.

摘要翻译： 用于通过部分肢体闭塞自动递送远程缺血调理治疗的单膀胱或双膀胱装置涉及操作袖带的各种方法，其中在袖带充气期间实现部分或全肢闭塞。 远程缺血调理的临床益处无需延长肢体血流停止的效果是有利的，因为所需的袖带压力较低，肢体脉管系统中凝块形成的风险降低。

公开(公告)号：US08974491B2

公开(公告)日：2015-03-10

申请号：US13836418

申请日：2013-03-15

申请人： Infarct Reduction Technologies Inc.

发明人： Boris Leschinsky

IPC分类号： A61B17/00 ,  A61B17/135 ,  A61B5/022 ,  A61B5/0225 ,  A61B5/00 ,  A61B5/11

CPC分类号： A61B17/1355 ,  A61B5/0002 ,  A61B5/02225 ,  A61B5/02233 ,  A61B5/0225 ,  A61B5/1112

摘要： Methods for adaptive cuff inflation for the purposes of occluding a limb of a subject include inflating a cuff to a pressure at or above limb occlusion pressure and periodically deflating the cuff to detect amplitude of oscillometric oscillations reaching or exceeding a predetermined threshold, whereby indicating that the cuff pressure has reached an updated systolic blood pressure. Selecting the cuff to be wide enough to define limb occlusion pressure at or below the systolic blood pressure assures that this maneuver does not compromise cessation of blood flow to the limb. Devices are disclosed configured to operate in at least two of the following three operating modes: a tourniquet mode, a remote conditioning mode and a blood pressure monitoring mode.

摘要翻译： 用于闭塞受试者肢体的适应性袖带充气的方法包括将袖带充气至肢体阻塞压力或高于肢体阻塞压力，并周期性地缩小袖带以检测达到或超过预定阈值的示波振荡的幅度，从而指示 袖带压力已经达到更新的收缩压。 选择足够宽的袖口以确定收缩压或低于收缩压的肢体闭塞压力，确保该手术不会损害肢体停止血液流动。 公开了被配置为以以下三种操作模式中的至少两种操作的装置：止血带模式，远程调节模式和血压监测模式。