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公开(公告)号：US11969425B2
公开(公告)日：2024-04-30
申请号：US18166789
申请日：2023-02-09
Applicant: InventisBio LLC
Inventor： Xing Dai , Yaolin Wang
IPC: A61K31/505 , A61K31/196 , A61K31/351 , A61K31/382 , A61K31/41 , A61K31/415 , A61K31/4155 , A61K31/4184 , C07C275/42 , C07D233/88 , C07D239/42 , C07D257/04 , C07D261/14 , C07D309/08 , C07D309/14 , C07D335/02 , C07D413/12
CPC classification number: A61K31/505 , A61K31/196 , A61K31/351 , A61K31/382 , A61K31/41 , A61K31/415 , A61K31/4155 , A61K31/4184 , C07C275/42 , C07D233/88 , C07D239/42 , C07D257/04 , C07D261/14 , C07D309/08 , C07D309/14 , C07D335/02 , C07D413/12
Abstract: The present disclosure provides compounds of Formula (I). The compounds described herein may be useful in treating a disease associated with IDO, for example, cancer or an infectious disease (e.g., viral or bacterial infectious diseases). Also, provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
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公开(公告)号：US20240025876A1
公开(公告)日：2024-01-25
申请号：US18211741
申请日：2023-06-20
Applicant: InventisBio Co., Ltd. , InventisBio LLC
Inventor： Wei LI , Yanqin LIU , Dongmei QIANG , Xiaojun WANG , Xing DAI
IPC: C07D401/12
CPC classification number: C07D401/12 , C07B2200/05
Abstract: Provided herein are compounds, crystalline free forms, crystalline salt forms, and pharmaceutical compositions of Compound 1. Also provided are methods of preparing and methods of using the same, e.g., for inhibiting a kinase and/or for treating various diseases or disorders, such as autoimmune diseases.
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公开(公告)号：US10980807B2
公开(公告)日：2021-04-20
申请号：US16073679
申请日：2017-02-08
Applicant: InventisBio LLC
Inventor： Xing Dai , Yaolin Wang
IPC: C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , A61K31/505 , A61K31/196 , A61K31/351 , A61K31/382 , A61K31/41 , A61K31/415 , A61K31/4155 , A61K31/4184 , C07C275/42 , C07D233/88 , C07D239/42 , C07D257/04 , C07D261/14 , C07D309/08 , C07D309/14 , C07D335/02 , C07D413/12
Abstract: The present disclosure provides compounds of Formula (I). The compounds described herein may be useful in treating a disease associated with IDO, for example, cancer or an infectious disease (e.g., viral or bacterial infectious diseases). Also, provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
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公开(公告)号：US20240343727A1
公开(公告)日：2024-10-17
申请号：US18578677
申请日：2022-08-16
Applicant: InventisBio Co., Ltd. , InventisBio LLC
Inventor： Xianhai HUANG , Younong YU , Haotao NIU , Hong YANG , Shanshan WANG , Jifang WENG , Yaolin WANG , Xing DAI
IPC: C07D471/04 , A61K31/501 , A61K31/502 , A61K31/5025 , A61K31/506 , A61K31/5377 , A61P35/00 , C07D401/14 , C07D403/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D487/10 , C07D491/052 , C07D491/107
CPC classification number: C07D471/04 , A61K31/501 , A61K31/502 , A61K31/5025 , A61K31/506 , A61K31/5377 , A61P35/00 , C07D401/14 , C07D403/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D487/10 , C07D491/052 , C07D491/107
Abstract: Provided herein are novel compounds, for example, compounds having a Formula (I), or a pharmaceutically acceptable salt thereof and pharmaceutical compositions comprising the same. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, in treating cancer.
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公开(公告)号：US20240043442A1
公开(公告)日：2024-02-08
申请号：US18220484
申请日：2023-07-11
Applicant: InventisBio LLC
Inventor： Xing DAI , Yaolin WANG
IPC: C07D495/04 , A61P35/00 , A61P5/32 , C07D471/04 , C07D471/14 , C07D491/048
CPC classification number: C07D495/04 , A61P35/00 , A61P5/32 , C07D471/04 , C07D471/14 , C07D491/048
Abstract: The present disclosure provides compounds of Formula (I) and Formula (II). The compounds described herein may be useful in treating proliferative diseases (e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
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Patent Agency Ranking
公开(公告)号：US20230357233A1
公开(公告)日：2023-11-09
申请号：US18042872
申请日：2021-08-26
Applicant: INVENTISBIO CO., LTD. , INVENTISBIO LLC
Inventor： Xing DAI , Hong YANG , Xianhai HUANG , Haotao NIU , Zixing HAN , Zhenwu WANG , Qiang ZHANG , Yanqin LIU , Yueheng JIANG , Liangshan TAO , Jifang WENG , Zhe SHI , Yaolin WANG
IPC: C07D471/04 , A61K45/06 , C07D519/00
CPC classification number: C07D471/04 , A61K45/06 , C07D519/00
Abstract: Provided herein are novel compounds, for example, compounds having a Formula (I), Formula (A), Formula (II), Formula (III), Formula (IV), or Formula (V), or a pharmaceutically acceptable salt thereof. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, in inhibiting KRASG12D in a cancer cell, and/or in treating various cancer such as pancreatic cancer, colorectal cancer, lung cancer (e.g., non-small cell lung cancer) or endometrial cancer.
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公开(公告)号：US20230338373A1
公开(公告)日：2023-10-26
申请号：US18166789
申请日：2023-02-09
Applicant: InventisBio LLC
Inventor： Xing DAI , Yaolin WANG
IPC: A61K31/505 , A61K31/196 , A61K31/351 , A61K31/382 , A61K31/41 , A61K31/415 , A61K31/4155 , A61K31/4184 , C07C275/42 , C07D233/88 , C07D239/42 , C07D257/04 , C07D261/14 , C07D309/08 , C07D309/14 , C07D335/02 , C07D413/12
CPC classification number: A61K31/505 , A61K31/196 , A61K31/351 , A61K31/382 , A61K31/41 , A61K31/415 , A61K31/4155 , A61K31/4184 , C07C275/42 , C07D233/88 , C07D239/42 , C07D257/04 , C07D261/14 , C07D309/08 , C07D309/14 , C07D335/02 , C07D413/12
Abstract: The present disclosure provides compounds of Formula (I). The compounds described herein may be useful in treating a disease associated with IDO, for example, cancer or an infectious disease (e.g., viral or bacterial infectious diseases). Also, provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
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公开(公告)号：US12187736B2
公开(公告)日：2025-01-07
申请号：US18220484
申请日：2023-07-11
Applicant: InventisBio LLC
Inventor： Xing Dai , Yaolin Wang
IPC: C07D471/04 , A61P5/32 , A61P35/00 , C07D471/14 , C07D491/04 , C07D491/048 , C07D495/04
Abstract: The present disclosure provides compounds of Formula (I) and Formula (II). The compounds described herein may be useful in treating proliferative diseases (e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
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公开(公告)号：US20220054486A1
公开(公告)日：2022-02-24
申请号：US17185278
申请日：2021-02-25
Applicant: InventisBio LLC
Inventor： Xing DAI , Yaolin Wang
IPC: A61K31/505 , A61K31/196 , A61K31/351 , A61K31/382 , A61K31/41 , A61K31/415 , A61K31/4155 , A61K31/4184 , C07C275/42 , C07D233/88 , C07D239/42 , C07D257/04 , C07D261/14 , C07D309/08 , C07D309/14 , C07D335/02 , C07D413/12
Abstract: The present disclosure provides compounds of Formula (I). The compounds described herein may be useful in treating a disease associated with IDO, for example, cancer or an infectious disease (e.g., viral or bacterial infectious diseases). Also, provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
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公开(公告)号：US20240140929A1
公开(公告)日：2024-05-02
申请号：US18268681
申请日：2021-12-22
Applicant: InventisBio Co., Ltd. , InventisBio LLC
Inventor： Xing DAI , Xianhai HUANG , Hong YANG , Zixing HAN , Haotao NIU , Jifang WENG , Zhe SHI , Yanqin LIU , Yueheng JIANG , Yaolin WANG
IPC: C07D401/12 , C07D213/75 , C07D237/24 , C07D253/075 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D513/04
CPC classification number: C07D401/12 , C07D213/75 , C07D237/24 , C07D253/075 , C07D401/14 , C07D405/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D513/04
Abstract: Provided herein are novel compounds, for example, compounds having a Formula (I), or a pharmaceutically acceptable N salt thereof. Also provided herein are methods of preparing the compounds and methods of using the compounds, for example, in inhibiting TYK2, and/or function of IL-12, IL-23 and/or INF-alpha, and/or in treating various associated diseases or disorders.
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