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公开(公告)号：US20130046169A1
公开(公告)日：2013-02-21
申请号：US13586489
申请日：2012-08-15
申请人： Irving N. WEINBERG , Pavel STEPANOV
发明人： Irving N. WEINBERG , Pavel STEPANOV
摘要： An apparatus and method direct nanoparticles in a body part under imaging guidance using at least one electromagnet configured and operable to create a magnetic field gradient used to direct the nanoparticles, wherein, the magnetic field gradient used to direct the nanoparticles does not substantially interfere with the use of magnetic field gradients whose purpose is to image the body part.
摘要翻译： 设备和方法使用至少一个电磁体在成像引导下在身体部分中直接纳米颗粒，所述电磁体被配置和可操作以产生用于引导纳米颗粒的磁场梯度，其中用于引导纳米颗粒的磁场梯度基本上不干扰 使用其目的是对身体部位进行成像的磁场梯度。
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2.发明申请公开(公告)号：US20120175584A1
公开(公告)日：2012-07-12
申请号：US13179681
申请日：2011-07-11
IPC分类号： H01L31/0352
摘要： Inorganic semiconducting materials such as silicon are used as a host matrix in which quantum dots reside to provide a radiation detector or energy converter. The quantum dot material may be disposed by incorporating materials sensitive to neutron detection such as boron-containing compounds, or the use of methods such as chemical vapor deposition or atomic layer deposition to insert the quantum dot material. Electrodes may be extended deep into the host matrix material to improve efficiency. Likewise, the host matrix may be machined to create pores in the matrix material. Further, amplification and signal-processing structures may be used in close proximity to the radiation-sensitive region of the device.
摘要翻译： 诸如硅之类的无机半导体材料用作其中量子点所在的主体矩阵，以提供辐射检测器或能量转换器。 量子点材料可以通过掺入对中子检测敏感的材料，例如含硼化合物，或使用诸如化学气相沉积或原子层沉积的方法来插入量子点材料来设置。 电极可以深入主体基质材料，以提高效率。 同样地，可以加工主体基质以在基体材料中产生孔。 此外，放大和信号处理结构可以紧邻设备的辐射敏感区域使用。
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公开(公告)号：US20130296631A1
公开(公告)日：2013-11-07
申请号：US13888684
申请日：2013-05-07
发明人： Irving N. WEINBERG , Lamar MAIR
IPC分类号： A61N2/00
CPC分类号： A61N2/004 , A61B17/3207 , A61B34/73 , A61B2017/00345 , A61B2018/00345 , A61B2018/00386 , A61N2/12 , B82Y5/00
摘要： Disclosed embodiments provide an apparatus and method for brushing plaques from vessels by exposing intraluminal nanoparticles to changing magnetic gradients.
摘要翻译： 公开的实施例提供了一种通过将管腔内纳米颗粒暴露于变化的磁梯度来从血管刷洗斑块的装置和方法。
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4.发明申请公开(公告)号：US20130257428A1
公开(公告)日：2013-10-03
申请号：US13903137
申请日：2013-05-28
发明人： Irving N. WEINBERG
CPC分类号： G01R33/4806 , A61B5/0042 , A61B5/0515 , A61B5/055
摘要： In accordance with disclosed embodiments, very high magnetic gradients and magnetic slew are applied to magnetizable particle imaging in order to realize high spatial resolution.
摘要翻译： 根据所公开的实施例，为了实现高空间分辨率，将非常高的磁梯度和磁转矩应用于可磁化的颗粒成像。
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公开(公告)号：US20130218010A1
公开(公告)日：2013-08-22
申请号：US13772579
申请日：2013-02-21
发明人： Irving N. WEINBERG , David BEYLIN
CPC分类号： A61B6/037 , A61B6/4405 , A61B6/481 , A61B6/501
摘要： In accordance with at least one disclosed embodiment, an apparatus for use in imaging the human brain by describing the distribution of radiotracers in the human brain is provided. The apparatus may be compact and lightweight enough to be lifted by hand (less than 50 pounds) and affixed to a patient bed. In addition, the apparatus may collect images of both the cerebrum and cerebellum of the patient.
摘要翻译： 根据至少一个所公开的实施例，提供了一种用于通过描述人脑中放射性示踪剂的分布来对人类大脑进行成像的装置。 该装置可以是紧凑和轻便的，足以用手提起（小于50磅）并固定在患者床上。 此外，该装置可以收集患者的大脑和小脑的图像。
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6.发明申请EQUIPMENT AND METHODOLOGIES FOR MAGNETICALLY-ASSISTED DELIVERY OF THERAPEUTIC AGENTS THROUGH BARRIERS 审中-公开通过障碍物自动辅助输送治疗药物的设备和方法公开(公告)号：US20130204120A1
公开(公告)日：2013-08-08
申请号：US13761200
申请日：2013-02-07
发明人： Irving N. WEINBERG
摘要： Magnetic gradients are used to transport Magnetic Nano Particles through a barrier, for example, the cribiform (also spelled “cribriform”) plate, which is a porous bony structure which separates the nasal cavity from the cranial vault. By utilizing a configuration of magnets (whether of the electromagnetic type or permanent magnets), MNPs can be propelled, pushed, pulled or otherwise manipulated in relation to an anatomical and/or physiological barrier, to position, re-position or maintain the position(s) of the MNPs.
摘要翻译： 磁梯度用于通过屏障输送磁性纳米颗粒，例如，将鼻腔与头颅分离的多孔骨结构的细骨状（也称为“骨架”）板。 通过利用磁体（无论是电磁型还是永磁体）的构型，可以相对于解剖学和/或生理屏障来推动，推动，拉动或以其他方式操纵MNP以定位，重新定位或维持位置（ s）的MNP。
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公开(公告)号：US20120116148A1
公开(公告)日：2012-05-10
申请号：US13290751
申请日：2011-11-07
IPC分类号： A61N2/00
CPC分类号： A61B34/73 , A61B34/70 , A61B2090/378
摘要： Disclosed embodiments are directed to reducing the likelihood of intra-operative shedding. Specifically, disclosed embodiments utilize injected magnetic nanoparticles and magnets to confine tumor cells to the surgical bed in order to prevent the cells from being released into the general circulation and/or lymphatics.
摘要翻译： 公开的实施例旨在降低手术中脱落的可能性。 具体地，所公开的实施例利用注射的磁性纳米颗粒和磁体将肿瘤细胞限制在外科手术床上，以防止细胞被释放到一般循环和/或淋巴管中。
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8.发明申请FLEXIBLE METHODS OF FABRICATING ELECTROMAGNETS AND RESULTING ELECTROMAGNET ELEMENTS 审中-公开制造电磁体和电磁元件的灵活方法公开(公告)号：US20120092105A1
公开(公告)日：2012-04-19
申请号：US13242386
申请日：2011-09-23
CPC分类号： H01F5/00 , B33Y70/00 , B33Y80/00 , H01F41/047 , Y10T29/49117
摘要： An electromagnetic structure is fabricated by additive manufacturing having at least one channel traversing the structure. In one embodiment, at least one form contains apertures and/or holes forming the channel and a liquid metal traverses the structure by the channel. Electrodes are provided to apply or extract electrical voltage or power to and/or from the liquid metal as well as a mechanism for propelling a portion of the liquid metal through the form. In an alternative embodiment, both the electrically insulating and the electrically conductive materials are solid and the channel is used for conducting a coolant instead of the liquid metal.
摘要翻译： 通过具有穿过该结构的至少一个通道的添加剂制造制造电磁结构。 在一个实施例中，至少一个形式包含形成通道的孔和/或孔，并且液体金属通过通道横穿结构。 提供电极以向液态金属施加或提取电压或电力，以及用于通过形式推动液态金属的一部分的机构。 在替代实施例中，电绝缘和导电材料都是实心的，并且通道用于传导冷却剂而不是液态金属。
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公开(公告)号：US06628984B2
公开(公告)日：2003-09-30
申请号：US09833110
申请日：2001-04-11
申请人： Irving N. Weinberg
发明人： Irving N. Weinberg
IPC分类号： A61B600
CPC分类号： G01T1/2985 , A61B6/037 , A61B6/4258
摘要： A tomographic imaging system includes a moveable detector or detectors capable of detecting gamma radiation; one or more position sensors for determining the position and angulation of the detector(s) in relation to a gamma ray emitting source; and a computational device for integrating the position and angulation of the detector(s) with information as to the energy and distribution of gamma rays detected by the detector and deriving a three dimensional representation of the source based on the integration. A method of imaging a radiation emitting lesion located in a volume of interest also is disclosed.
摘要翻译： 断层成像系统包括能够检测伽马射线的可移动检测器或检测器; 一个或多个位置传感器，用于确定检测器相对于伽马射线发射源的位置和角度; 以及用于将检测器的位置和角度与用于由检测器检测到的γ射线的能量和分布的信息相关的信息进行积分的计算装置，并且基于该积分导出源的三维表示。 还公开了一种对位于感兴趣体积中的辐射发射损伤进行成像的方法。
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公开(公告)号：US06555380B2
公开(公告)日：2003-04-29
申请号：US09784700
申请日：2001-02-15
申请人： Irving N. Weinberg
发明人： Irving N. Weinberg
IPC分类号： G01N2300
CPC分类号： G01N23/04 , A61B6/4258 , A61B6/481 , Y10T436/25
摘要： A system for describing the physical distribution of an agent that accumulates selectively in tissue of a patient in an excised surgical specimen. The system comprises an agent which selectively concentrates in a cancer or precancer or focus of infection or other pathological condition. The system comprises a detector sensitive to the agent which is present in the surgical specimen. The system also comprises an apparatus capable of forming an image based on the information gathered by the detector, and which image describes the physical distribution of the agent in the surgical specimen so that a surgeon can be guided by the image provided by the apparatus, the apparatus connected to said detector.
摘要翻译： 一种用于描述在切除的手术样本中有选择地积聚在患者组织中的药剂的物理分布的系统。 该系统包括选择性地集中在癌症或癌前期或感染或其他病理状况的焦点中的药剂。 该系统包括对存在于手术标本中的药剂敏感的检测器。 该系统还包括能够基于由检测器收集的信息形成图像的装置，以及哪个图像描述了外科手术样本中的药剂的物理分布，使得外科医生可以由该装置提供的图像引导， 连接到所述检测器的装置。
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