公开(公告)号：US06300504B1

公开(公告)日：2001-10-09

申请号：US09218847

申请日：1998-12-22

Applicant: Jacob J. Guth ,  Samual A. Vona, Jr. ,  John S. Thomaides ,  Paul M. Petersen ,  Carmine Iovine

Inventor： Jacob J. Guth ,  Samual A. Vona, Jr. ,  John S. Thomaides ,  Paul M. Petersen ,  Carmine Iovine

IPC: A61K711

CPC classification number: A61K8/88 ,  A61Q3/00 ,  A61Q5/00

Abstract: This invention relates to water-soluble/dispersible reactive imido and polyimido compounds, wherein the polyimido compounds may be selected from the group consisting of polysuccinimide compounds, polyglutimide compounds, and copolymers of thereof. The polyimido compounds comprise a water-solubilizing/dispersing moiety that provides water-solubility and/or water-dispersibility to the polyimido compound and preferably is derived from a nucleophilic moiety selected from the group consisting of amines, alcohols, phenols, thiols, and carboxylates. The present invention also pertains to a proteinaceous substrate to which the imido or polyimido compound has been covalently bonded and to a method for treating a proteinaceous substrate with the imido or polyimido compound.

Abstract translation: 本发明涉及水溶性/分散性反应性亚氨基和聚酰亚胺化合物，其中聚亚胺化合物可以选自聚琥珀酰亚胺化合物，聚ut酰亚胺化合物及其共聚物。 聚酰亚胺化合物包括水溶性/分散部分，其向聚亚胺化合物提供水溶性和/或水分散性，并且优选衍生自选自胺，醇，酚，硫醇和羧酸酯的亲核部分 。 本发明还涉及亚氨基或聚酰亚胺化合物已经共价键合的蛋白质底物和用亚氨基或聚亚氨基化合物处理蛋白质底物的方法。

公开(公告)号：US6143817A

公开(公告)日：2000-11-07

申请号：US167920

申请日：1998-10-07

Applicant: Malcolm Hallam ,  Grant T. Shouldice ,  Jacob J. Guth

Inventor： Malcolm Hallam ,  Grant T. Shouldice ,  Jacob J. Guth

IPC: C08F2/16 ,  C08F2/24 ,  C08F2/32 ,  C08F2/44 ,  C08L77/00

CPC classification number: C08F2/24

Abstract: This invention relates to a stabilized aqueous emulsion polymerization composition comprising (a) from about 10% to about 80% by weight of a polymer derived from an emulsion polymerizable ethylenically unsaturated monomer; (b) from about 0.1% to about 10% by weight of a polyamino acid heteropolymer; (c) from about 0.01% to about 1% by weight of a free radical polymerization initiating agent; and (d) the remainder water. The polyamino acid heteropolymer in (b) may be selected from the group consisting of polyaspartic acid heteropolymers, polyglutamic acid heteropolymers, copolymers of polyaspartic acid heteropolymers with polyglutamic acid heteropolymers, and mixtures thereof. The present invention also pertains to a method for emulsifying and stabilizing an aqueous free radical emulsion polymerization reaction employing the polyamino acid heteropolymers.

Abstract translation: 本发明涉及一种稳定的水性乳液聚合组合物，其包含（a）约10％至约80％重量的衍生自可乳液聚合的烯属不饱和单体的聚合物; （b）约0.1％至约10％重量的聚氨基酸杂聚物; （c）约0.01重量％至约1重量％的自由基聚合引发剂; 和（d）剩余的水。 （b）中的聚氨基酸杂聚物可以选自聚天冬氨酸杂聚物，聚谷氨酸异聚物，聚天冬氨酸杂聚物与聚谷氨酸杂聚物的共聚物及其混合物。 本发明还涉及使用聚氨基酸杂聚物乳化和稳定含水自由基乳液聚合反应的方法。

公开(公告)号：US4576757A

公开(公告)日：1986-03-18

申请号：US604267

申请日：1984-04-26

Applicant: Jacob J. Guth ,  Elvin R. Lukenbach ,  Richard R. Tenore

Inventor： Jacob J. Guth ,  Elvin R. Lukenbach ,  Richard R. Tenore

IPC: C07C67/00 ,  C07C231/00 ,  C07C231/02 ,  C07C233/36 ,  C11D1/40 ,  C07C102/00

CPC classification number: C07C231/02

Abstract: A process for the preparation of monoacyl polyalkylene polyamines comprising reacting a fatty acid ester with a polyalkylene polyamine in the presence of a suitable hydroxylic solvent.

Abstract translation: 一种制备单酰基聚亚烷基多胺的方法，包括在合适的羟基溶剂存在下使脂肪酸酯与聚亚烷基多胺反应。

公开(公告)号：US4443362A

公开(公告)日：1984-04-17

申请号：US278284

申请日：1981-06-29

Applicant: Jacob J. Guth ,  Robert J. Verdicchio

Inventor： Jacob J. Guth ,  Robert J. Verdicchio

IPC: C07C51/00 ,  C07C59/125 ,  C07C67/00 ,  C07C227/00 ,  C07C229/16 ,  C07C231/00 ,  C07C233/36 ,  C07C233/89 ,  C07C301/00 ,  C07C309/13 ,  C07C309/14 ,  C07F9/09 ,  C11D1/06 ,  C11D1/88 ,  C11D1/94 ,  C07C101/04 ,  C07C101/20

CPC classification number: C11D3/0094 ,  A61K8/39 ,  A61K8/44 ,  C07C59/125 ,  C11D1/06 ,  C11D1/88 ,  C11D1/94 ,  A61Q5/02

Abstract: Novel amphoteric-alkoxylated carboxylate complexes are described as well as detergent compositions containing said complexes.

Abstract translation: 描述了新型两性烷氧基化羧酸盐络合物以及含有所述复合物的洗涤剂组合物。

公开(公告)号：US4435300A

公开(公告)日：1984-03-06

申请号：US375074

申请日：1982-05-05

Applicant: Jacob J. Guth ,  Diane L. Spilatro ,  Robert J. Verdicchio

Inventor： Jacob J. Guth ,  Diane L. Spilatro ,  Robert J. Verdicchio

IPC: C11D1/04 ,  C11D1/08 ,  C11D1/10 ,  C11D1/12 ,  C11D1/28 ,  C11D1/32 ,  C11D1/88 ,  C11D1/90 ,  C11D1/92 ,  C11D1/94 ,  C11D1/65

CPC classification number: A61K8/44 ,  A61K8/361 ,  A61K8/466 ,  A61Q19/10 ,  A61Q5/02 ,  C11D1/88 ,  C11D1/886 ,  C11D1/90 ,  C11D1/92 ,  C11D1/94 ,  A61K2800/596 ,  A61K2800/75 ,  A61Q5/12 ,  C11D1/04 ,  C11D1/08 ,  C11D1/10 ,  C11D1/123 ,  C11D1/28 ,  C11D1/32

Abstract: An improved low irritating detergent and cleansing composition exhibiting good foam properties is disclosed. The composition is a synergistic mixture of an amphoteric-fatty acid complex and an anionic surfactant containing at least one carboxylic acid moiety.

Abstract translation: 公开了一种改进的低刺激性洗涤剂和表现出良好泡沫性能的清洁组合物。 该组合物是包含至少一个羧酸部分的两性 - 脂肪酸配合物和阴离子表面活性剂的协同混合物。

公开(公告)号：US06306378B1

公开(公告)日：2001-10-23

申请号：US09287900

申请日：1999-04-07

Applicant: Jacob J. Guth ,  Samuel A. Vona, Jr. ,  John S. Thomaides ,  Ann C. Savoca

Inventor： Jacob J. Guth ,  Samuel A. Vona, Jr. ,  John S. Thomaides ,  Ann C. Savoca

IPC: A61K711

CPC classification number: A61Q5/12 ,  A61K8/41 ,  A61K8/418 ,  A61K8/46 ,  A61K8/463 ,  A61K8/4913 ,  A61K8/4926 ,  A61K8/8164 ,  A61K8/84 ,  A61K8/88 ,  A61K2800/43 ,  A61K2800/57 ,  A61K2800/94 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/10 ,  A61Q17/04 ,  A61Q19/00

Abstract: This invention relates to a two-part system useful for treating proteinaceous substrates. The two-part system has a first part comprising a water-soluble/dispersible reactive polyimido compound and a second part comprising a nucleophilic catalytic agent. The polyimido compounds may be selected from the group consisting of polysuccinimide compounds, polyglutimide compounds, and copolymers of thereof. The polyimido compound may also comprise a functionalizing moiety that provides functionality to the polyimido compound and is preferably derived from a nucleophilic moiety selected from the group consisting of amines, alcohols, phenols, thiols, and carboxylates; and a water-solubilizing/dispersing moiety that provides water-solubility and/or water-dispersibility to the polyimido compound and is preferably derived from a nucleophilic moiety selected from the group consisting of amines, alcohols, phenols, thiols, and carboxylates. The nucleophilic catalytic agent serves to catalyze nuclephilic substitution of the polyimido compound by the proteinaceous substrate. The invention also pertains to a method for treating a proteinaceous substrate with the two-part system and to a composition comprising a mixture of the polyimido compound and the nucleophilic catalytic agent.

Abstract translation: 本发明涉及可用于处理蛋白质底物的两部分系统。 两部分系统具有包含水溶性/分散性反应性聚酰亚胺化合物的第一部分和包含亲核催化剂的第二部分。 聚酰亚胺化合物可以选自聚琥珀酰亚胺化合物，聚戊二酰亚胺化合物及其共聚物。 聚酰亚胺化合物还可以包含向聚亚胺化合物提供官能团的官能化部分，并且优选衍生自选自胺，醇，酚，硫醇和羧酸酯的亲核部分; 以及向聚酰亚胺化合物提供水溶性和/或水分散性的水溶性/分散部分，并且优选衍生自选自胺，醇，酚，硫醇和羧酸盐的亲核部分。 亲核催化剂用于催化蛋白质底物对聚酰亚胺化合物的亲核取代。 本发明还涉及用两部分系统处理蛋白质底物的方法以及包含聚酰亚胺化合物和亲核催化剂的混合物的组合物。

公开(公告)号：US06303794B1

公开(公告)日：2001-10-16

申请号：US09218846

申请日：1998-12-22

Applicant: Jacob J. Guth ,  Samual A. Vona, Jr. ,  John S. Thomaides ,  Doreen Howard ,  Paul M. Petersen ,  Carmine Iovine

Inventor： Jacob J. Guth ,  Samual A. Vona, Jr. ,  John S. Thomaides ,  Doreen Howard ,  Paul M. Petersen ,  Carmine Iovine

IPC: A61K711

CPC classification number: A61Q19/00 ,  A61K8/41 ,  A61K8/418 ,  A61K8/46 ,  A61K8/463 ,  A61K8/4913 ,  A61K8/4926 ,  A61K8/8164 ,  A61K8/84 ,  A61K8/88 ,  A61K2800/43 ,  A61K2800/57 ,  A61K2800/94 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q17/04

Abstract: This invention relates to water-soluble/dispersible reactive functionalized imido and polyimido compounds, wherein the polyimido compounds may be selected from the group consisting of polysuccinimide compounds, polyglutimide compounds, and copolymers of thereof. The polyimido compound comprises a functionalizing moiety F that provides functionality to the polyimido compound and is preferably derived from a nucleophilic moiety selected from the group consisting of amines, alcohols, phenols, thiols, and carboxylates; and a water-solubilizing/dispersing moiety that provides water-solubility and/or water-dispersibility to the polyimido compound and is preferably derived from a nucleophilic moiety selected from the group consisting of amines, alcohols, phenols, thiols, and carboxylates. The invention also pertains to a proteinaceous substrate to which the imido or polyimido compound has been covalently bonded and to a method for treating a proteinaceous substrate with the imido or polyimido compound.

Abstract translation: 本发明涉及水溶性/分散性反应性官能化亚氨基和聚酰亚胺化合物，其中聚亚胺化合物可以选自聚琥珀酰亚胺化合物，聚戊二酰亚胺化合物及其共聚物。 聚酰亚胺化合物包括官能化部分F，其提供聚酰亚胺化合物的官能团，并且优选衍生自选自胺，醇，酚，硫醇和羧酸酯的亲核部分; 以及向聚酰亚胺化合物提供水溶性和/或水分散性的水溶性/分散部分，并且优选衍生自选自胺，醇，酚，硫醇和羧酸盐的亲核部分。 本发明还涉及亚氨基或聚亚氨基化合物共价键合的蛋白质底物和用亚氨基或聚亚氨基化合物处理蛋白质底物的方法。

公开(公告)号：US4511513A

公开(公告)日：1985-04-16

申请号：US375073

申请日：1982-05-05

Applicant: Jacob J. Guth ,  Robert J. Verdicchio

Inventor： Jacob J. Guth ,  Robert J. Verdicchio

IPC: C07C53/126 ,  C07F9/09 ,  C11D1/52 ,  C11D1/88 ,  C07C103/54

CPC classification number: A61K8/361 ,  A61K8/44 ,  C07C53/126 ,  C07F9/091 ,  C11D1/88 ,  A61K2800/596 ,  A61K2800/75 ,  A61Q19/10 ,  A61Q5/02 ,  A61Q5/12

Abstract: Novel amphoteric-fatty acid complexes are described as well as detergent compositions containing said complexes.

Abstract translation: 描述了新型两性脂肪酸复合物以及含有所述复合物的洗涤剂组合物。

公开(公告)号：US06329319B1

公开(公告)日：2001-12-11

申请号：US09382434

申请日：1999-08-25

Applicant: Christine Puglisi ,  Jacob J. Guth

Inventor： Christine Puglisi ,  Jacob J. Guth

IPC: A01N2526

CPC classification number: A01C1/06

Abstract: A seed coating composition for low temperature applications, said seed coating composition comprising at least one polymer having a Tg of −60° C. to 20° C., provided that the Tg of the polymer is less than or equal to the seed surface temperature at the time of application. The seed coating compositions of the invention provide a matrix which entraps active ingredients and improves seedling survival by maintaining the active ingredient on the surface of the seed for a period of time. The seed coating also increases the safety of using an active ingredient by reducing operator exposure and environmental release. In addition, the seed coating composition is resistant to cracking and flaking even when the seed coating composition is applied at a temperature of less than 20° C. Moreover, the seed coating composition improves the uniformity of seed size and shape which is advantageous to mechanical planting techniques.

Abstract translation: 用于低温应用的种子包衣组合物，所述种子包衣组合物包含至少一种Tg为-60℃至20℃的聚合物，条件是聚合物的Tg小于或等于种子表面温度 在申请时。 本发明的种子包衣组合物提供了通过将种子表面上的活性成分维持一段时间来捕获活性成分并改善幼苗存活的基质。 种子涂层还通过减少操作者的暴露和环境释放来增加使用活性成分的安全性。 此外，种子包衣组合物即使在低于20℃的温度下施用种子包衣组合物也耐龟裂和剥落。此外，种子包衣组合物改善种子大小和形状的均匀性，这有利于机械 种植技术。

公开(公告)号：US5288493A

公开(公告)日：1994-02-22

申请号：US10094

申请日：1993-01-28

Applicant: Gary T. Martino ,  Dinesh C. Patel ,  Jacob J. Guth

Inventor： Gary T. Martino ,  Dinesh C. Patel ,  Jacob J. Guth

IPC: A61K8/81 ,  A61K9/00 ,  A61K9/107 ,  A61K9/12 ,  A61K47/32 ,  A61Q19/00

CPC classification number: A61K8/8158 ,  A61K47/32 ,  A61K9/0014 ,  A61Q19/00 ,  A61Q1/06 ,  A61Q17/04 ,  Y10S514/937 ,  Y10S514/957

Abstract: Skin care compositions, such as creams and lotions, wherein improved rub-off resistance is attained by including an effective amount of a copolymer comprising:a) 10-75% by wt. of a C.sub.1 to C.sub.18 alkyl acrylate/methacrylate,b) 10-70% by wt. of C.sub.1 to C.sub.18 N-substituted alkyl acrylamide, andc) 5-40% by wt. of unsaturated carboxylic acid having 3 to 5 carbon atoms.

Abstract translation: 皮肤护理组合物，例如乳膏和洗剂，其中通过包括有效量的共聚物来实现改进的耐擦性，所述共聚物包含：a）10-75重量％ 的C1-C18烷基丙烯酸酯/甲基丙烯酸酯，b）10-70重量％ 的C 1 -C 18 N-取代的烷基丙烯酰胺，和c）5-40重量％ 的具有3至5个碳原子的不饱和羧酸。