公开(公告)号：US08377987B2

公开(公告)日：2013-02-19

申请号：US12647843

申请日：2009-12-28

Applicant: Allan Sy Lau ,  Lai Hung Cindy Yang ,  Chi Chung Stanley Chik ,  Chun Bong James Li

Inventor： Allan Sy Lau ,  Lai Hung Cindy Yang ,  Chi Chung Stanley Chik ,  Chun Bong James Li

IPC: A61K31/235

CPC classification number: C07C59/64 ,  A61K31/235 ,  C07C69/734

Abstract: The present invention provides compounds, and compositions comprising these compounds, which have immunomodulatory activity and/or anti-inflammatory activity.

公开(公告)号：US20120166292A1

公开(公告)日：2012-06-28

申请号：US12979928

申请日：2010-12-28

Applicant: Eric Bax ,  James Li ,  Nilanjan Roy ,  Joaquin A. Delgado

Inventor： Eric Bax ,  James Li ,  Nilanjan Roy ,  Joaquin A. Delgado

IPC: G06Q30/00

CPC classification number: G06Q30/0241 ,  G06Q30/0275

Abstract: Systems and methods for pricing portfolio allocations of ad deliveries to a plurality of online ads are disclosed. A first set of values is determined, each value of the first set of values representing for an online ad of the plurality of online ads, a bid an advertiser has associated with the online ad. A second set of values is determined, the second set of values representing statistics on variability of payoffs from showing ads. A risk value associated with the publisher is determined. Using a portfolio allocation algorithm, a set of ad delivery allocations associated with the plurality of online ads is determined, and, using a Vickrey-Clarke-Groves mechanism, a set of prices associated with the plurality of online ads is determined, both of which are determined based on the first set of values, the second set of values, and the risk value.

Abstract translation: 公开了将广告交付给多个在线广告的投资组合分配定价的系统和方法。 确定第一组值，第一组值的每个值表示多个在线广告的在线广告，广告主已经与在线广告相关联的出价。 确定第二组值，第二组值表示展示广告的收益变化的统计数据。 确定与发布商相关联的风险值。 使用投资组合分配算法，确定与多个在线广告相关联的一组广告传送分配，并且使用Vickrey-Clarke-Groves机制确定与多个在线广告相关联的一组价格，其中两者 基于第一组值，第二组值和风险值来确定。

公开(公告)号：US20100184856A1

公开(公告)日：2010-07-22

申请号：US12647843

申请日：2009-12-28

Applicant: Allan Sy Lau ,  Lai Hung Cindy Yang ,  Chi Chung Stanley Chik ,  Chun Bong James Li

Inventor： Allan Sy Lau ,  Lai Hung Cindy Yang ,  Chi Chung Stanley Chik ,  Chun Bong James Li

IPC: A61K31/216 ,  C07C69/734 ,  A61P37/02 ,  A61P29/00 ,  A61P1/00 ,  A61P27/14 ,  A61P37/06 ,  A61P9/00 ,  A61P11/00 ,  A61P19/02

CPC classification number: C07C59/64 ,  A61K31/235 ,  C07C69/734

Abstract: The present invention provides compounds, and compositions comprising these compounds, which have immunomodulatory activity and/or anti-inflammatory activity.

Abstract translation: 本发明提供了具有免疫调节活性和/或抗炎活性的化合物和包含这些化合物的组合物。

公开(公告)号：US07549444B2

公开(公告)日：2009-06-23

申请号：US11315679

申请日：2005-12-22

Applicant: James Li ,  Peter Berkman

Inventor： James Li ,  Peter Berkman

IPC: F16K1/30 ,  F16K15/18

CPC classification number: F16K3/085 ,  E03B7/12 ,  Y10T137/698 ,  Y10T137/7668 ,  Y10T137/88054

Abstract: A frost free faucet having a spigot assembly including a drain conduit, a sleeve assembly including an elongated pipe, and a valve assembly. The valve assembly includes a ½ turn valve, a check valve and optionally a pressure relief mechanism. The ½ turn valve includes a rotatable valve element configured with a water passageway and a stationary valve element with one or through holes. The rotatable valve element is circular-shaped and configured with a water passageway in a semicircular portion. The stationary element is a disc shaped configured with one or more through-holes in a semi-circular portion of the stationary valve element. Upon turning the rotatable valve element 180 degrees in a first direction, the water passageway and the one or more through-holes are aligned to an open position and upon turning the rotatable element 180 degrees in a second direction, the water passageway and the one or more through-holes are misaligned to a closed position. Each valve element of the ½ turn valve may be formed from a ceramic material, The check valve is located upstream of the ½ turn valve to prevent the backflow of water from the spigot to the supply line. An optional pressure relief mechanism allows water trapped downstream of the valve assembly to be discharged from the valve assembly.

Abstract translation: 一种无霜水龙头，其具有包括排水导管，包括细长管的套筒组件和阀组件的插口组件。 阀组件包括½转阀，止回阀和任选的压力释放机构。 ½转阀包括构造有水通道的可旋转阀元件和具有一个或多个通孔的固定阀元件。 可旋转的阀元件是圆形的并且构造成具有半圆形部分的水通道。 固定元件是在固定阀元件的半圆形部分中形成有一个或多个通孔的盘形。 在将可旋转阀元件沿第一方向旋转180度时，水通道和一个或多个通孔对准到打开位置，并且在将可旋转元件沿第二方向180度转动时，水通道和一个或多个通孔 更多的通孔不对齐到关闭位置。 ½转阀的每个阀元件可以由陶瓷材料形成。 止回阀位于½转阀门的上游，以防止水从管接头回流到供应管路。 可选的压力释放机构允许捕获在阀组件下游的水从阀组件排出。

公开(公告)号：US20090009409A1

公开(公告)日：2009-01-08

申请号：US12231804

申请日：2008-09-05

Applicant: James Li ,  Jing Jiang

Inventor： James Li ,  Jing Jiang

IPC: H01Q1/24 ,  H01Q1/38

CPC classification number: H01Q1/2291 ,  H01Q1/242 ,  H01Q1/36 ,  H01Q5/371 ,  H01Q5/40 ,  H01Q9/0464 ,  H01Q9/36 ,  H01Q21/28

Abstract: An antenna system includes first, second and third antennas that are arranged on a substrate. The first, second and third antennas include an arc-shaped element having a concave side and a convex side and a conducting element that extends substantially radially from a center of said concave side.

Abstract translation: 天线系统包括布置在基板上的第一，第二和第三天线。 第一，第二和第三天线包括具有凹面和凸面的弧形元件和从所述凹面的中心大致径向延伸的导电元件。

公开(公告)号：US20080217176A1

公开(公告)日：2008-09-11

申请号：US11715405

申请日：2007-03-08

Applicant: Shioujenq Andrew Lin ,  Yingjeng James Li

Inventor： Shioujenq Andrew Lin ,  Yingjeng James Li

IPC: C25B7/00 ,  C25B9/00

CPC classification number: B01D53/326 ,  B01D53/86 ,  B01D2255/102 ,  B01D2255/20707 ,  B01D2255/908 ,  B01D2256/12 ,  B01D2259/4533 ,  B01D2259/4541

Abstract: The fast and convenient usage of clean and pure oxygen supply devices will meet the requirements of medical application and special environment safety issues. The electrochemical oxygen concentration is a device by using an electrochemical reactor of one electrode of oxygen reduction and another electrode of oxygen generation. The operation of electrochemical reactor can achieve the easy control of air oxygen from one side to another side of this thin mask structure and the materials, design and engineering of this electrochemical oxygen concentration is workable for medical application.

Abstract translation: 清洁，纯氧供应装置的快速方便使用将满足医疗应用和特殊环境安全问题的要求。 电化学氧浓度是通过使用一个氧还原电极的电化学反应器和另一个氧气发生电极的装置。 电化学反应器的操作可以实现对这种薄掩模结构的一侧到另一侧的空气氧的容易控制，并且该电化学氧浓度的材料，设计和工程可用于医疗应用。

公开(公告)号：US07423597B2

公开(公告)日：2008-09-09

申请号：US11519979

申请日：2006-09-12

Applicant: James Li ,  Jing Jiang

Inventor： James Li ,  Jing Jiang

IPC: H01Q1/24

CPC classification number: H01Q1/2291 ,  H01Q1/242 ,  H01Q1/36 ,  H01Q5/371 ,  H01Q5/40 ,  H01Q9/0464 ,  H01Q9/36 ,  H01Q21/28

Abstract: An antenna system comprises first, second, and third antennas that are arranged on a printed circuit board (PCB) and that include an arc-shaped element having a concave side and a convex side, and a conducting element that extends substantially radially from a center of the concave side.

Abstract translation: 天线系统包括布置在印刷电路板（PCB）上的第一，第二和第三天线，其包括具有凹面和凸面的弧形元件，以及从中心大致径向延伸的导电元件 的凹面。

公开(公告)号：US07394433B2

公开(公告)日：2008-07-01

申请号：US11581502

申请日：2006-10-16

Applicant: James Li ,  Jing Jiang

Inventor： James Li ,  Jing Jiang

IPC: H01Q1/24

CPC classification number: H01Q1/2291 ,  H01Q1/242 ,  H01Q1/36 ,  H01Q5/371 ,  H01Q5/40 ,  H01Q9/0464 ,  H01Q9/36 ,  H01Q21/28

Abstract: An antenna system comprises first, second, and third antennas that are arranged on a printed circuit board (PCB) and that include an arc-shaped element having a concave side and a convex side. A conducting element extends substantially radially from a center of the concave side. A U-shaped element has a base portion with a center that communicates with the conducting element and two side portions that extend from ends of the base portion towards the concave side.

Abstract translation: 天线系统包括布置在印刷电路板（PCB）上的第一，第二和第三天线，并且包括具有凹面和凸面的弧形元件。 导电元件从凹面的中心大致径向地延伸。 U形元件具有与导电元件连通的中心的基部和从基部的端部朝向凹侧延伸的两个侧部。

公开(公告)号：US20060287357A1

公开(公告)日：2006-12-21

申请号：US11448947

申请日：2006-06-07

Applicant: James Li ,  Lawrence Hamann ,  Haixia Wang ,  Zheming Ruan ,  Christopher Cooper ,  Jun Li ,  Jeffrey Robl

Inventor： James Li ,  Lawrence Hamann ,  Haixia Wang ,  Zheming Ruan ,  Christopher Cooper ,  Jun Li ,  Jeffrey Robl

IPC: A61K31/4745 ,  C07D471/02

CPC classification number: C07D471/04

Abstract: Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure: or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L, R3, R3a, R3b and R4 are defined herein.

Abstract translation: 提供了新的化合物，其为11-β-羟基类固醇脱氢酶I型抑制剂。 11-β-羟基类固醇脱氢酶I型抑制剂可用于治疗，预防或减缓需要11-β-羟基类固醇脱氢酶I型抑制剂治疗的疾病进展。 这些新化合物具有以下结构：或其立体异构体或前药或其药学上可接受的盐，其中W，L，R 3，R 3a，R 3b， >和R 4'在本文中定义。

公开(公告)号：US20060281105A1

公开(公告)日：2006-12-14

申请号：US11400026

申请日：2006-04-07

Applicant: Honghua Li ,  James Li

Inventor： Honghua Li ,  James Li

IPC: C12Q1/68 ,  G06F19/00 ,  C12P19/34

CPC classification number: C12Q1/6869 ,  G16B25/00 ,  G16B30/00 ,  C12Q2537/143 ,  C12Q2531/113 ,  C12Q2525/185

Abstract: The present invention provides methods of designing PCR primers that allow the efficient and simultaneous amplification of a large number of different desired DNA fragments in a single multiplex PCR and minimize the formation of nonspecific extensions of undesired DNA fragments. The present invention allows a multiplex PCR to use at least 50 pairs of primers and produce at least 50 DNA fragments of interest. The present invention significantly broadens the application of multiplex PCR in the identification of multiple genes related to multifactorial diseases, the genome-scale detection of genetic alterations, the studies in large-scale pharmacogenetic reactions, the genotyping genetic polymorphism in a large population, the gene expression profiling in various samples, and high throughput genotyping technologies.

Abstract translation: 本发明提供了设计PCR引物的方法，其允许在单个多重PCR中有效并同时扩增大量不同的所需DNA片段，并使非特异性DNA片段的非特异性延伸的形成最小化。 本发明允许多重PCR使用至少50对引物并产生至少50个感兴趣的DNA片段。 本发明显着拓宽了多重PCR在多因素相关基因鉴定中的应用，遗传改变的基因组大小检测，大规模药物遗传反应的研究，大群体的基因型遗传多态性，基因 各种样品中的表达谱，以及高通量基因分型技术。