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公开(公告)号：US20100069857A1
公开(公告)日：2010-03-18
申请号：US12233510
申请日：2008-09-18
申请人： James M. Christensen
发明人： James M. Christensen
CPC分类号： B29C35/0894 , A61F2/14 , A61F9/0017 , A61F2210/0004 , A61F2240/004 , B29C2035/0827
摘要： A collagen corneal shield for placement on the outer surface of the eye for protection of the eye, for delivery of drugs to the eye, or for both protection and drug delivery to the eye, functions without obstructing vision. The shield has a first, central portion comprising non-crosslinked collagen capable of rapid decomposition in the presence of enzymes in the tears, and a second portion comprising crosslinked collagen which decomposes slowly in the presence of enzymes in the tears so that it remains on the eye for a period of time longer than the first portion. The first portion of the shield covers the central portion of the cornea and the second portion of the shield extends outward from the first portion. As a result of decomposition of the first portion the corneal shield becomes a ring or washer shape around the central portion and at least a portion of the cornea is no longer covered by the shield so that vision is not obstructed. The corneal shield can also be contoured so that it has one or more base curve radii selected to provide retention of the shield on the eye.
摘要翻译： 用于放置在眼睛外表面上的胶原角膜护罩，用于保护眼睛，将药物递送至眼睛，或用于保护和药物输送到眼睛，功能而不会阻碍视力。 护罩具有第一中心部分，其包含能够在泪液中的酶存在下快速分解的非交联胶原蛋白，以及包含交联胶原蛋白的第二部分，其在泪液存在下缓慢分解，使得其保留在 眼睛比第一部分长一段时间。 护罩的第一部分覆盖角膜的中心部分，并且护罩的第二部分从第一部分向外延伸。 作为第一部分分解的结果，角膜屏蔽件围绕中心部分变成环形或垫圈形状，并且至少一部分角膜不再被屏蔽物覆盖，使得视力不被阻挡。 角膜屏蔽也可以被轮廓化，使得其具有一个或多个基本曲线半径，以选择保护屏幕在眼睛上。
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公开(公告)号：US06569128B1
公开(公告)日：2003-05-27
申请号：US09400579
申请日：1999-09-22
申请人： James M. Christensen , John A. Krug
发明人： James M. Christensen , John A. Krug
IPC分类号： A61M500
CPC分类号： A61M5/16877 , A61M5/16804 , A61M2025/0042 , A61M2025/0089 , A61M2025/0091
摘要： An infusion catheter with an adjustable flow contains a flow restrictor tube located in the lumen of the catheter. The flow rate through the infusion catheter can be adjusted by reducing the length of the flow restrictor tube and infusion catheter assembly.
摘要翻译： 具有可调流量的输液导管包含位于导管内腔中的限流器管。 可以通过减少限流管和输液导管组件的长度来调节通过输注导管的流速。
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公开(公告)号：US5116371A
公开(公告)日：1992-05-26
申请号：US549096
申请日：1990-07-06
摘要： An implantable prosthesis comprises a hydrogel enclosed within a flexible envelope. The hydrogel contains both hydrophilic and hydrophobic domains. It is prepared by copolymerizing a hydrophilic monomer such as water soluble N-vinylpyrrolidone, acrylates or methacrylates with non-water soluble monomers such as acrylates, methacrylates, N-vinyl carbazole, its derivatives, or a non-water soluble derivative of N-vinylpyrrolidone. The flexible envelope may be either porous or non-porous. The hydrogel may be either solid or composed of particles of a size greater than the porosity of the envelope.
摘要翻译： 可植入假体包括封闭在柔性封套内的水凝胶。 水凝胶含有亲水和疏水结构域。 通过将亲水性单体如水溶性N-乙烯基吡咯烷酮，丙烯酸酯或甲基丙烯酸酯与非水溶性单体如丙烯酸酯，甲基丙烯酸酯，N-乙烯基咔唑，其衍生物或N-乙烯基吡咯烷酮的非水溶性衍生物 。 柔性包层可以是多孔的或非多孔的。 水凝胶可以是固体，也可以由尺寸大于外壳的孔隙度的颗粒组成。
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公开(公告)号：US07985208B2
公开(公告)日：2011-07-26
申请号：US12233510
申请日：2008-09-18
申请人： James M. Christensen
发明人： James M. Christensen
CPC分类号： B29C35/0894 , A61F2/14 , A61F9/0017 , A61F2210/0004 , A61F2240/004 , B29C2035/0827
摘要： A collagen corneal shield for placement on the outer surface of the eye for protection of the eye, for delivery of drugs to the eye, or for both protection and drug delivery to the eye, functions without obstructing vision. The shield has a first, central portion comprising non-crosslinked collagen capable of rapid decomposition in the presence of enzymes in the tears, and a second portion comprising crosslinked collagen which decomposes slowly in the presence of enzymes in the tears so that it remains on the eye for a period of time longer than the first portion. The first portion of the shield covers the central portion of the cornea and the second portion of the shield extends outward from the first portion. As a result of decomposition of the first portion the corneal shield becomes a ring or washer shape around the central portion and at least a portion of the cornea is no longer covered by the shield so that vision is not obstructed. The corneal shield can also be contoured so that it has one or more base curve radii selected to provide retention of the shield on the eye.
摘要翻译： 用于放置在眼睛外表面上的胶原角膜护罩，用于保护眼睛，将药物递送至眼睛，或用于保护和药物输送到眼睛，功能而不会阻碍视力。 护罩具有第一中心部分，其包含能够在泪液中的酶存在下快速分解的非交联胶原蛋白，以及包含交联胶原蛋白的第二部分，其在泪液存在下缓慢分解，使得其保留在 眼睛比第一部分长一段时间。 护罩的第一部分覆盖角膜的中心部分，并且护罩的第二部分从第一部分向外延伸。 作为第一部分分解的结果，角膜屏蔽件围绕中心部分变成环形或垫圈形状，并且至少一部分角膜不再被屏蔽物覆盖，使得视力不被阻挡。 角膜屏蔽也可以被轮廓化，使得其具有一个或多个基本曲线半径，以选择保护屏幕在眼睛上。
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公开(公告)号：US06645183B2
公开(公告)日：2003-11-11
申请号：US10046098
申请日：2001-11-08
IPC分类号： A61M500
CPC分类号： A61M5/16804 , A61M5/16877 , A61M2025/0042 , A61M2025/0089 , A61M2025/0091
摘要： A micro-bore catheter for use with an infusion pump wherein the micro-bore lumen of the catheter acts as an adjustable flow restricting element. The flow rate through the catheter can be increased proportionally by trimming the length of the catheter. One end of the catheter is attached to a needle for insertion of the catheter into the elastomeric septum of a drug infusion pump.
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公开(公告)号：USD277784S
公开(公告)日：1985-02-26
申请号：US392360
申请日：1982-06-25
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公开(公告)号：US4432361A
公开(公告)日：1984-02-21
申请号：US340520
申请日：1982-01-18
摘要： A completely portable, continuously self-monitoring device for expediting the healing of bone or soft tissue fractures or defects in a patient is disclosed herein along with its method of use. This device includes an electrical power supply, electronic circuitry and an arrangement of electrodes for applying current in a regulated manner through the fracture or defect site in a way which has been found to expedite the healing of bone fractures or bone defects at the site. The device also includes a monitoring arrangement cooperating with its power supply, electronic circuitry and arrangement of electrodes for continuously detecting and visually indicating whether or not the power supply is in proper working order and whether or not current is flowing through the fracture or defect site.
摘要翻译： 本文公开了一种用于加速患者骨骼或软组织骨折或缺陷的愈合的完全便携式，连续自我监测装置及其使用方法。 该装置包括电源，电子电路和电极的布置，用于以已调节的方式通过破裂或缺陷部位以调节的方式施加电流，以加速骨折或骨缺损处的愈合。 该装置还包括与其电源，电子电路和电极布置配合的监视装置，用于连续检测和可视地指示电源是否处于正确的工作状态，以及电流是否流过裂缝或缺陷部位。
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公开(公告)号：USD277509S
公开(公告)日：1985-02-05
申请号：US394636
申请日：1982-07-01
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9.发明授权Bone and tissue healing device including a special electrode assembly and method 失效骨和组织愈合装置包括一个特殊的电极组件和方法
公开(公告)号：US4461300A
公开(公告)日：1984-07-24
申请号：US340521
申请日：1982-01-18
申请人： James M. Christensen
发明人： James M. Christensen
摘要： A portable device used for expediting the healing of bone or soft tissue fractures or defects in a patient is disclosed herein and utilizes at least one cathode electrode, an anode electrode and a circuit arrangement for applying a regulated flow of current between the electrodes and through the fracture or defect site. A specifically designed electrode assembly including the cathode electrode is also disclosed herein along with a particular technique for placing the cathode electrode in position at the fracture or defect site.
摘要翻译： 本文公开了用于加速骨骼或软组织骨折或患者的缺陷愈合的便携式装置，并且利用至少一个阴极电极，阳极电极和电路装置，用于在电极之间施加稳定的电流流并通过 骨折或缺损部位。 本文还公开了包括阴极电极的专门设计的电极组件以及用于将阴极电极置于断裂或缺陷位置处的特定技术。
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公开(公告)号：US4871367A
公开(公告)日：1989-10-03
申请号：US92415
申请日：1987-09-03
CPC分类号： A61F2/4241 , A61F2002/30154 , A61F2002/30176 , A61F2002/30273 , A61F2002/30276 , A61F2002/30563 , A61F2002/30596 , A61F2002/3082 , A61F2002/30878 , A61F2002/4251 , A61F2230/0021 , A61F2230/0054 , A61F2230/0086
摘要： A surgically implantable prosthesis for replacing a bone joint, specifically the knuckle, of an individual is disclosed herein. The prosthesis includes a one-piece main body of flexible, inert material including first and second spaced apart end sections and a narrower web extending between and joining the sections together for flexing movement about a particular flexing axis through the web, whereby the main body functions as a hinge. First and second elongated stems connected to and extend out from these end sections in directions normal to the flexing axis and away from one another. In accordance with one feature of the prosthesis disclosed herein, a specific one of the stems is laterally offset in a specific way with respect to the flexing axis. In accordance with another feature, the end sections and web of the main body together define the key-hole shaped groove across one side of the web between the end sections.
摘要翻译： 本文公开了用于替换个体的骨关节，特别是关节的用于外科手术植入的假体。 假体包括柔性惰性材料的一体式主体，包括第一和第二间隔开的端部部分，以及在这些部分之间延伸并将部分连接在一起的较窄的腹板，用于围绕特定的弯曲轴线穿过腹板弯曲运动，由此主体功能 作为铰链。 第一和第二细长杆在垂直于弯曲轴线并且彼此远离的方向上从这些端部部分连接并从该端部部分延伸出来。 根据本文公开的假体的一个特征，杆中的特定一个相对于弯曲轴线以特定方式横向偏移。 根据另一个特征，主体的端部和腹板一起在端部之间限定跨越腹板的一侧的键孔形凹槽。
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