利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

4 条记录 (耗时 0.015 秒)

    Heterocyclic substituted acylaminothiazoles, their preparation and pharmaceutical compositions containing them
    1.
    再颁专利
    Heterocyclic substituted acylaminothiazoles, their preparation and pharmaceutical compositions containing them 失效
    杂环取代的酰基氨基噻唑，它们的制备和含有它们的药物组合物

    公开(公告)号：USRE37094E1

    公开(公告)日：2001-03-13

    申请号：US08526079

    申请日：1995-09-11

    申请人： Daniel Fréhel ,  Danielle Gully ,  Gérard Valette ,  Jean-Pierre Bras

    发明人： Daniel Fréhel ,  Danielle Gully ,  Gérard Valette ,  Jean-Pierre Bras

    IPC分类号： C07D41712

    CPC分类号： C07D417/12 ,  C07D417/14 ,  C07D495/04

    摘要： Compounds of formula in which R1 represents H, an alkyl or a substituted alkyl, R2 represents H or alkyl and R3 represents an optionally substituted cycloalkyl or an optionally substituted aromatic group, which can be a phenyl or a heterocyclic group comprising one or more hetero-atoms chosen from O, S and N, or R2 and R3 considered together represent the group which is optionally substituted on the phenyl ring, and Z represents a heterocycle comprising one or more heteroatoms chosen from O, S and N, fused with an aromatic ring which can comprise a hetero-atom and can be substituted, the said heterocycle being optionally substituted on N, when it comprises such an atom, by an alkyl or a substituted alkyl group, and the salts of these compounds with acids or bases. Use of these compounds as medicaments. No figure.

    摘要翻译： R1表示H，烷基或取代的烷基的式的化合物，R 2表示H或烷基，R 3表示任选取代的环烷基或任选取代的芳族基团，其可以是包含一个或多个杂原子的苯基或杂环基 选自O，S和N，或一起考虑的R2和R3表示在苯环上任选取代的基团，Z表示包含一个或多个选自O，S和N的杂原子的杂环，其与芳环稠合， 包含杂原子并且可以被取代，当其包含这种原子，烷基或取代烷基时，所述杂环任选被取代，并且这些化合物与酸或碱的盐。使用这些化合物 作为药物无图。