公开(公告)号：US07538146B2

公开(公告)日：2009-05-26

申请号：US11618800

申请日：2006-12-30

申请人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorge Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

发明人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorge Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

IPC分类号： C08F290/06

CPC分类号： G02B1/043 ,  A61L27/26 ,  B29C39/42 ,  B29C71/00 ,  B29L2011/0041 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  C08L43/04 ,  C08L75/04 ,  C08L51/085 ,  C08L2666/20 ,  C08L51/08 ,  C08L83/04 ,  C08L33/00 ,  C08G18/63 ,  C08G18/48

摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

公开(公告)号：US07468398B2

公开(公告)日：2008-12-23

申请号：US11146586

申请日：2005-06-07

申请人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorg Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

发明人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorg Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

IPC分类号： C08F290/06

CPC分类号： G02B1/043 ,  A61L27/26 ,  B29C39/42 ,  B29C71/00 ,  B29L2011/0041 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  C08L43/04 ,  C08L75/04 ,  C08L51/085 ,  C08L2666/20 ,  C08L51/08 ,  C08L83/04 ,  C08L33/00 ,  C08G18/63 ,  C08G18/48

摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

摘要翻译： 一种适用于眼睛延长磨损期至少一天的眼科镜片，没有临床显着量的角膜肿胀，并且没有实质的佩戴者不适。 透镜具有透氧性和离子或水渗透性的平衡，离子或水渗透性足以提供良好的眼内运动，使得透镜和眼睛之间发生良好的泪液交换。 优选的透镜是含氧大分子单体和离子单体单体的共聚产物。 本发明包括长期佩戴的隐形眼镜，其包括具有从内表面延伸到外表面的氧透过和离子传播途径的核心。

公开(公告)号：US5945498A

公开(公告)日：1999-08-31

申请号：US776985

申请日：1997-12-22

申请人： Jens Hopken ,  Dieter Lohmann ,  Angelika Domschke

发明人： Jens Hopken ,  Dieter Lohmann ,  Angelika Domschke

IPC分类号： G02C7/04 ,  A61F20060101 ,  A61F2/14 ,  A61L27/00 ,  A61L27/26 ,  A61L27/34 ,  B05D7/24 ,  B29C39/42 ,  B29C71/00 ,  B29D11/00 ,  C08F220/22 ,  C08F290/06 ,  C08F290/14 ,  C08F299/02 ,  C08F299/08 ,  C08G20060101 ,  C08G18/10 ,  C08G18/48 ,  C08G18/50 ,  C08G18/61 ,  C08G18/67 ,  C08G18/81 ,  C08G18/83 ,  C08G77/00 ,  C08G77/04 ,  C08G77/46 ,  C08J5/00 ,  C08K3/00 ,  C08L20060101 ,  C08L33/08 ,  C08L33/10 ,  C08L83/04 ,  G02B1/04 ,  G02C20060101 ,  C08G77/24

CPC分类号： B29D11/00076 ,  A61L27/26 ,  A61L27/34 ,  B05D1/62 ,  B29C39/42 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  G02B1/043 ,  B29C71/00 ,  B29L2011/0041 ,  Y10S525/903 ,  Y10S525/936 ,  Y10S525/937 ,  Y10T428/3154 ,  Y10T428/31544 ,  Y10T428/31663

摘要： The present invention describes a free radical polymerizable segmented macromonomer based on perfluoroelkyl ether, polysiloxane and divalent organic segments. This macromoner can be polymerized and used to form moldings, contact lenses, corneal implants and other biomedical articles.

摘要翻译： PCT No.PCT / EP96 / 01255 Sec。 371 1997年12月22日第 102（e）日期1997年12月22日PCT提交1996年3月22日PCT公布。 公开号WO96 / 31791 日期：1996年10月10日本发明描述了基于全氟烷基醚，聚硅氧烷和二价有机链段的自由基可聚合分段大分子单体。 这种大分子单体可以被聚合并用于形成模制品，隐形眼镜，角膜植入物和其它生物医学制品。

公开(公告)号：US08568626B2

公开(公告)日：2013-10-29

申请号：US12252406

申请日：2008-10-16

申请人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorge Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

发明人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorge Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

IPC分类号： B29D11/00

CPC分类号： G02C7/049 ,  A61L27/26 ,  A61L27/34 ,  A61L2430/16 ,  B05D1/62 ,  B29C39/42 ,  B29C71/00 ,  B29D11/00076 ,  B29L2011/0041 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  G02B1/043 ,  Y10S525/903 ,  Y10S525/936 ,  Y10S525/937 ,  C08L51/085 ,  C08L51/08 ,  C08L33/00 ,  C08L83/04 ,  C08L39/06 ,  C08G18/63 ,  C08G18/48

摘要： A method for making a silicone hydrogel contact lens is provided. In one embodiment, a prepolymer mixture is polymerized in a lens mold in an atmosphere having less than about 10000 ppm oxygen to form a silicone hydrogel contact lens suitable for extended wear as characterized by producing less than 10% corneal swelling after a period of continuous wear of 7 days including normal sleep periods. In one embodiment, the prepolymer mixture comprises at least one oxyperm material containing hydrophilic groups, wherein the at least one oxyperm material is a siloxane-containing macromer or monomer, at least one ionoperm material, and a cross-linking agent. In certain embodiments, the polymerization of the prepolymer mixture may be carried out in an atmosphere having less than about 1000 ppm oxygen.

摘要翻译： 提供了制备硅酮水凝胶隐形眼镜的方法。 在一个实施方案中，预聚物混合物在具有小于约10000ppm氧气的气氛中在透镜模具中聚合以形成适于延长磨损的硅氧烷水凝胶隐形眼镜，其特征在于连续磨损一段时间后产生小于10％的角膜溶胀 包括正常睡眠期为7天。 在一个实施方案中，预聚物混合物包含至少一种含有亲水基团的含氧物质，其中所述至少一种含氧物质是含硅氧烷的大分子单体或至少一种离子交换材料和交联剂。 在某些实施方案中，预聚物混合物的聚合可以在具有小于约1000ppm氧气的气氛中进行。

公开(公告)号：US20090039535A1

公开(公告)日：2009-02-12

申请号：US12252406

申请日：2008-10-16

申请人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorg Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, JR. ,  Jurgen Vogt ,  Lynn Cook Winterton

发明人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorg Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, JR. ,  Jurgen Vogt ,  Lynn Cook Winterton

IPC分类号： B29D11/00

CPC分类号： G02C7/049 ,  A61L27/26 ,  A61L27/34 ,  A61L2430/16 ,  B05D1/62 ,  B29C39/42 ,  B29C71/00 ,  B29D11/00076 ,  B29L2011/0041 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  G02B1/043 ,  Y10S525/903 ,  Y10S525/936 ,  Y10S525/937 ,  C08L51/085 ,  C08L51/08 ,  C08L33/00 ,  C08L83/04 ,  C08L39/06 ,  C08G18/63 ,  C08G18/48

摘要： A method for making a silicone hydrogel contact lens is provided. In one embodiment, a prepolymer mixture is polymerized in a lens mold in an atmosphere having less than about ppm oxygen to form a silicone hydrogel contact lens suitable for extended wear as characterized by producing less than 10% corneal swelling after a period of continuous wear of 7 days including normal sleep periods. In one embodiment, the prepolymer mixture comprises at least one oxyperm material containing hydrophilic groups, wherein the at least one oxyperm material is a siloxane-containing macromer or monomer, at least one ionperm material, and a cross-linking agent. In certain embodiments, the polymerization of the prepolymer mixture may be carried out in an atmosphere having less than about 1000 ppm oxygen.

摘要翻译： 提供了制备硅酮水凝胶隐形眼镜的方法。 在一个实施方案中，预聚物混合物在具有小于约ppm氧气的气氛中在透镜模具中聚合以形成适于延长磨损的硅氧烷水凝胶隐形眼镜，其特征在于在连续磨损一段时间后产生小于10％的角膜溶胀 包括正常睡眠期的7天。 在一个实施方案中，预聚物混合物包含至少一种含有亲水基团的含氧物质，其中所述至少一种含氧物质是含硅氧烷的大分子单体或单体，至少一种离子精子材料和交联剂。 在某些实施方案中，预聚物混合物的聚合可以在具有小于约1000ppm氧气的气氛中进行。

公开(公告)号：US5807944A

公开(公告)日：1998-09-15

申请号：US671278

申请日：1996-06-27

申请人： Thomas Hirt ,  Dieter Lohmann ,  Jens Hopken ,  Qin Liu

发明人： Thomas Hirt ,  Dieter Lohmann ,  Jens Hopken ,  Qin Liu

IPC分类号： G02C7/04 ,  C08F261/06 ,  C08F265/00 ,  C08F290/02 ,  C08F290/06 ,  C08G18/81 ,  C08G65/02 ,  C08G73/00 ,  C08G85/00 ,  G02B1/04 ,  C08F30/08

CPC分类号： G02B1/043 ,  C08F290/02 ,  Y10S525/937

摘要： The subject matter of the present invention is an amphiphilic, segmented copolymer of controlled morphology comprising at least one segment having high oxygen permeability, at least one segment having high ion and water permeability, the segments being linked together through a non-hydrolizable bond, and at least one polymerizable unsaturated group; a process for the preparation of the copolymer; to polymeric products obtainable by further polymerizing and optionally cross-linking the amphiphilic segmented copolymer, and to mouldings, especially contact lenses and other ophthalmic devices comprising a polymeric product of the invention. In a specifically preferred embodiment, the present invention relates to a contact lens comprising a polymeric product of the invention which is suited for extended periods of wear.

摘要翻译： 本发明的主题是受控形态的两亲性，分段共聚物，其包含至少一个具有高透氧性的片段，至少一个具有高离子和水渗透性的片段，该片段通过不可水解的键连接在一起，以及 至少一个可聚合不饱和基团; 一种制备该共聚物的方法; 可通过进一步聚合和任选地交联两亲性分段共聚物获得的聚合产物，以及包含本发明的聚合物的模制品，特别是隐形眼镜和其它眼科装置。 在一个特别优选的实施方案中，本发明涉及一种隐形眼镜，其包含适合延长磨损期的本发明的聚合物产品。

公开(公告)号：US07553880B2

公开(公告)日：2009-06-30

申请号：US11618798

申请日：2006-12-30

申请人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorge Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

发明人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorge Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

IPC分类号： G02B1/04

CPC分类号： G02B1/043 ,  A61L27/26 ,  B29C39/42 ,  B29C71/00 ,  B29L2011/0041 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  C08L43/04 ,  C08L75/04 ,  C08L51/085 ,  C08L2666/20 ,  C08L51/08 ,  C08L83/04 ,  C08L33/00 ,  C08G18/63 ,  C08G18/48

摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

摘要翻译： 一种适用于眼睛延长磨损期至少一天的眼科镜片，没有临床显着量的角膜肿胀，并且没有实质的佩戴者不适。 透镜具有透氧性和离子或水渗透性的平衡，离子或水渗透性足以提供良好的眼内运动，使得透镜和眼睛之间发生良好的泪液交换。 优选的透镜是含氧大分子单体和离子单体单体的共聚产物。 本发明包括长期佩戴的隐形眼镜，其包括具有从内表面延伸到外表面的氧透过和离子传播途径的核心。

公开(公告)号：US20050228065A1

公开(公告)日：2005-10-13

申请号：US11146586

申请日：2005-06-07

申请人： Paul Nicolson ,  Richard Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Terry ,  Jurgen Vogt ,  Lynn Winterton

发明人： Paul Nicolson ,  Richard Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Terry ,  Jurgen Vogt ,  Lynn Winterton

IPC分类号： A61L27/26 ,  B29C39/42 ,  B29C71/00 ,  C08G18/10 ,  C08G18/48 ,  C08G18/50 ,  C08G18/61 ,  C08G18/67 ,  C08G18/81 ,  C08K3/00 ,  C08L43/04 ,  C08L75/04 ,  G02B1/04

CPC分类号： G02B1/043 ,  A61L27/26 ,  B29C39/42 ,  B29C71/00 ,  B29L2011/0041 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  C08L43/04 ,  C08L75/04 ,  C08L51/085 ,  C08L2666/20 ,  C08L51/08 ,  C08L83/04 ,  C08L33/00 ,  C08G18/63 ,  C08G18/48

摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

公开(公告)号：US5965631A

公开(公告)日：1999-10-12

申请号：US108714

申请日：1998-07-01

申请人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorg Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

发明人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorg Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

IPC分类号： G02C7/04 ,  A61F20060101 ,  A61F2/14 ,  A61L27/00 ,  A61L27/26 ,  A61L27/34 ,  B05D7/24 ,  B29C39/42 ,  B29C71/00 ,  B29D11/00 ,  C08F220/22 ,  C08F290/06 ,  C08F290/14 ,  C08F299/08 ,  C08G20060101 ,  C08G18/10 ,  C08G18/48 ,  C08G18/50 ,  C08G18/61 ,  C08G18/67 ,  C08G18/81 ,  C08G18/83 ,  C08G77/00 ,  C08G77/04 ,  C08G77/46 ,  C08J5/00 ,  C08K3/00 ,  C08L20060101 ,  C08L33/08 ,  C08L33/10 ,  C08L83/04 ,  G02B1/04 ,  G02C20060101

CPC分类号： G02C7/049 ,  A61L27/26 ,  A61L27/34 ,  B05D1/62 ,  B29C39/42 ,  B29D11/00076 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  G02B1/043 ,  A61L2430/16 ,  B29C71/00 ,  B29L2011/0041 ,  Y10S525/903 ,  Y10S525/936 ,  Y10S525/937

摘要： An ophthalmic lens suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

公开(公告)号：US5760100A

公开(公告)日：1998-06-02

申请号：US569816

申请日：1995-12-08

申请人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorg Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

发明人： Paul Clement Nicolson ,  Richard Carlton Baron ,  Peter Chabrecek ,  John Court ,  Angelika Domschke ,  Hans Jorg Griesser ,  Arthur Ho ,  Jens Hopken ,  Bronwyn Glenice Laycock ,  Qin Liu ,  Dieter Lohmann ,  Gordon Francis Meijs ,  Eric Papaspiliotopoulos ,  Judy Smith Riffle ,  Klaus Schindhelm ,  Deborah Sweeney ,  Wilson Leonard Terry, Jr. ,  Jurgen Vogt ,  Lynn Cook Winterton

IPC分类号： G02C7/04 ,  A61F20060101 ,  A61F2/14 ,  A61L27/00 ,  A61L27/26 ,  A61L27/34 ,  B05D7/24 ,  B29C39/42 ,  B29C71/00 ,  B29D11/00 ,  C08F220/22 ,  C08F290/06 ,  C08F290/14 ,  C08F299/08 ,  C08G20060101 ,  C08G18/10 ,  C08G18/48 ,  C08G18/50 ,  C08G18/61 ,  C08G18/67 ,  C08G18/81 ,  C08G18/83 ,  C08G77/00 ,  C08G77/04 ,  C08G77/46 ,  C08J5/00 ,  C08K3/00 ,  C08L20060101 ,  C08L33/08 ,  C08L33/10 ,  C08L83/04 ,  G02B1/04 ,  G02C20060101

CPC分类号： G02C7/049 ,  A61L27/26 ,  A61L27/34 ,  B05D1/62 ,  B29C39/42 ,  B29D11/00076 ,  C08G18/10 ,  C08G18/4833 ,  C08G18/5015 ,  C08G18/61 ,  C08G18/672 ,  C08G18/8116 ,  C08G18/8175 ,  G02B1/043 ,  A61L2430/16 ,  B29C71/00 ,  B29L2011/0041 ,  Y10S525/903 ,  Y10S525/936 ,  Y10S525/937

摘要： An ophthalmic lens suited for extended-wear for periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of a oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.