公开(公告)号：US08637021B2

公开(公告)日：2014-01-28

申请号：US12740845

申请日：2008-11-12

申请人： Alessandra Del Rio ,  Gianluca Rinaldi ,  Joel Richard

发明人： Alessandra Del Rio ,  Gianluca Rinaldi ,  Joel Richard

IPC分类号： A61K39/395

CPC分类号： C07K14/70578 ,  A61K9/0019 ,  A61K47/12 ,  A61K47/26 ,  C07K2319/30

摘要： The invention relates to formulations of TACI-Immunoglobulin fusion proteins.

摘要翻译： 本发明涉及TACI-免疫球蛋白融合蛋白的制剂。

公开(公告)号：US20120202660A1

公开(公告)日：2012-08-09

申请号：US13443740

申请日：2012-04-10

申请人： Ben Silverman ,  Joel Richard Grenz ,  Darren Shane

发明人： Ben Silverman ,  Joel Richard Grenz ,  Darren Shane

IPC分类号： A63B21/00

CPC分类号： A63B7/00 ,  A63B21/0023 ,  A63B21/16 ,  A63B21/1645 ,  A63B2023/006 ,  A63B2208/029 ,  A63B2225/09 ,  Y10S482/904

摘要： An exercise strap comprises an upper strap and a lower strap. A plurality of loop members are located on the lower strap to allow for handles to be easily removed and replaced on different locations on the lower strap. An adjustment member attached to both the upper strap and the lower strap allows for the overall length of the exercise strap to be adjusted. A strap attachment member attached to the upper strap connects the exercise strap to a suitable mounting mechanism.

摘要翻译： 运动皮带包括上带和下带。 多个环构件位于下带上，以允许手柄在下带上的不同位置容易地移除和更换。 附接到上带和下带的调节构件允许调整运动带的整个长度。 附接到上带的皮带附件将健身带连接到合适的安装机构。

公开(公告)号：US20100239529A1

公开(公告)日：2010-09-23

申请号：US12738375

申请日：2008-12-18

申请人： Alessandra Del Rio ,  Joel Richard

发明人： Alessandra Del Rio ,  Joel Richard

IPC分类号： A61K38/21 ,  A61P43/00 ,  A61J1/00

CPC分类号： A61K9/0019 ,  A61K38/21 ,  A61K38/215 ,  A61K47/26 ,  A61K47/34 ,  A61K47/60 ,  A61K2300/00 ,  C07K14/555 ,  C07K14/565

摘要： The invention relates to a liquid pharmaceutical composition comprising a pegylated IFN-β (PEG-IFN-β), an excipient, a surfactant and a buffer wherein said excipient is a polyol, wherein said surfactant is a non-ionic surfactant and wherein said buffer is a sodium acetate buffer.

摘要翻译： 本发明涉及一种液体药物组合物，其包含聚乙二醇化的IFN- （PEG-IFN-和bgr），赋形剂，表面活性剂和缓冲液，其中所述赋形剂是多元醇，其中所述表面活性剂是非离子表面活性剂，其中所述缓冲液是乙酸钠缓冲液。

公开(公告)号：US20090191135A1

公开(公告)日：2009-07-30

申请号：US12355696

申请日：2009-01-16

申请人： Joel RICHARD ,  Frantz Deschamps ,  Patrick Lacroix-Desmazes ,  Bernard Boutevin

发明人： Joel RICHARD ,  Frantz Deschamps ,  Patrick Lacroix-Desmazes ,  Bernard Boutevin

IPC分类号： A61K9/12

CPC分类号： C08L53/00 ,  A61K9/2018 ,  A61K9/2054 ,  A61K9/2866 ,  A61K9/2886 ,  C08F293/005 ,  C08L53/005 ,  Y02P20/544 ,  C08L2666/02

摘要： A method for encapsulating an active principle by dispersing the active principle in a supercritical fluid by adding a surfactant to the fluid. The surfactant is a block copolymer having at least one CO2-philic block and at least one nonionic hydrophilic block.

摘要翻译： 一种通过向流体中加入表面活性剂将活性成分分散在超临界流体中来包封活性成分的方法。 表面活性剂是具有至少一个CO 2亲和嵌段和至少一个非离子亲水嵌段的嵌段共聚物。

公开(公告)号：US5901174A

公开(公告)日：1999-05-04

申请号：US878620

申请日：1997-06-19

申请人： Joel Richard

发明人： Joel Richard

IPC分类号： H04B7/08 ,  H04L1/06 ,  H03H7/30 ,  G06F17/10 ,  H03H5/00

CPC分类号： H04L1/06 ,  H04B7/0851

摘要： An equalizer-combiner for a diversity receiver using at least two receive channels computes equalization coefficients for each channel allowing for a first channel error signal representative of a comparison between the demodulated signal and a channel estimate of the transmitted source signal delivered by a channel estimator fed with the demodulated signal in the channel during an acquisition phase and a second channel error signal representative of a comparison between the demodulated signal and the global estimate of the transmitted source signal during a normal operation phase. The equalizer-combiner computes the weighting coefficients allowing for a first global error signal representative of a comparison between the combined signal and the global estimate of the source signal during the acquisition phase a second global error signal representative of a comparison between local reference information known to the receiver and corresponding received reference information periodically extracted from the global estimate during the normal operation phase.

摘要翻译： 用于使用至少两个接收信道的分集接收机的均衡器组合器计算每个信道的均衡系数，允许表示解调信号与由馈送的信道估计器传送的发射源信号的信道估计之间的比较的第一信道误差信号 在采集阶段期间信道中的解调信号和表示在正常操作阶段期间解调信号与发射源信号的全局估计之间的比较的第二信道误差信号。 均衡器组合器计算加权系数，允许表示在采集阶段期间组合信号与源信号的全局估计之间的比较的第一全局误差信号，第二全局误差信号表示已知为 在正常操作阶段期间从全局估计周期性地提取接收机和对应的接收到的参考信息。

公开(公告)号：US5783643A

公开(公告)日：1998-07-21

申请号：US803213

申请日：1997-02-21

申请人： Bernard Chauvel ,  Joel Richard

发明人： Bernard Chauvel ,  Joel Richard

IPC分类号： C08K5/00 ,  C08F8/30 ,  C08F8/34 ,  C08F8/42 ,  C08K5/45 ,  C08L33/02 ,  C08L35/06 ,  C08L47/00 ,  C08L101/00 ,  G06K9/48 ,  H01B1/12 ,  H01B1/20 ,  H01B1/06

CPC分类号： G06K9/48 ,  H01B1/121 ,  C08F2800/10

摘要： Polymeric compositions well suited for conversion into electroconductive shaped articles, e.g., films, comprise at least one convertible polymer (Pm) and at least one amphiphilic organic compound (B) which comprises a charge transfer complex or a radical ion salt having the formula (I): D.sub.d A.sub.a Z.sub.z, in which D is an electron donor; A is an electron acceptor; Z is a doping agent which itself can be a non-amphiphilic electron donor or electron acceptor, with the proviso that at least one of D and A is amphiphilic and contains at least one saturated or unsaturated hydrocarbon substituent having at least 10 carbon atoms; d is a number equal to or greater than 0; a is a number equal to or greater than 0; and z is a number equal to or greater than 0, with the further proviso that at least one of the symbols d and a is a number greater than 0.

公开(公告)号：US5716855A

公开(公告)日：1998-02-10

申请号：US586673

申请日：1996-03-01

申请人： Dan Lerner ,  Frederic Ricchiero ,  Joel Richard ,  Dominique Teychenne ,  Sophie Vaslin

发明人： Dan Lerner ,  Frederic Ricchiero ,  Joel Richard ,  Dominique Teychenne ,  Sophie Vaslin

IPC分类号： G01N33/533 ,  C08F2/22 ,  C08F2/44 ,  C08K5/00 ,  C08K9/10 ,  C08L101/00 ,  C09B67/08 ,  C09K11/06 ,  G01N33/545 ,  G01N33/58 ,  G01N21/64 ,  C09K11/02

CPC分类号： G01N33/585 ,  C08K5/0041 ,  C08K9/10 ,  G01N33/582 ,  G01N2800/52 ,  Y10S436/80

摘要： A fluorescent latex with particles containing at least one encapsulated hydrophobic fluorochrome A (acceptor) and at least one encapsulated hydrophobic fluorochrome D (donor), wherein A is different from D and exposure to light radiation enables the emission from fluorochrome D to excite fluorochrome A, and a method for producing said latex and its use as a marker, particularly a biological marker, are also disclosed.

摘要翻译： PCT No.PCT / FR94 / 00867 Sec。 371日期1996年3月1日 102（e）1996年3月1日PCT 1994年11月7日PCT PCT。 出版物WO95 / 02635 日期1995年1月26日具有包含至少一个包封的疏水性荧光染料A（受体）和至少一个封装的疏水性荧光染料D（供体）的颗粒的荧光胶乳，其中A与D不同并且暴露于光辐射使得能够从荧光染料D 激发荧光染料A，并且还公开了制备所述胶乳的方法及其作为标记物，特别是生物标记物的用途。

公开(公告)号：US5357502A

公开(公告)日：1994-10-18

申请号：US39964

申请日：1993-03-30

申请人： Damien Castelain ,  Joel Richard ,  Roselyne Halbert-Lasselle ,  Daniel Pommier

发明人： Damien Castelain ,  Joel Richard ,  Roselyne Halbert-Lasselle ,  Daniel Pommier

IPC分类号： H04L27/26 ,  H04B7/02 ,  H04L1/02

CPC分类号： H04L27/2649

摘要： A device for the reception of digital data broadcast at a high bit rate for reception by mobile receivers is disclosed. The device operates under adverse conditions of multiple propagation corresponding to the Rayleigh process and imperfect frequency tuning to minimize the inter-symbol interference in the frequency domain. The device receives a digital signal having digital elements distributed in the frequency-time space f-t and transmitted in the form of symbols each constituted by a multiplex of N orthogonal carrier frequencies modulated by a set of digital elements and broadcast simultaneously. The device includes a module for transposition by a local oscillator, baseband filtering and analog-digital conversion, a temporal windowing module for the selection of the useful samples and a mathematical transformation module, the temporal windowing module applying a Nyquist window type of temporal window with non-zero roll-off.

摘要翻译： 公开了一种用于接收以高比特率广播以便移动接收机接收的数字数据的装置。 该装置在对应于瑞利处理的多个传播的不利条件和不完美的频率调谐下工作，以最小化频域中的符号间干扰。 该装置接收数字信号，该数字信号具有分布在频率 - 时间空间f-t中的数字信号，并且以每个由一组数字元素调制的N个正交载波的多路复用构成的码元形式发送并同时广播。 该装置包括用于通过本地振荡器进行转置的模块，基带滤波和模拟数字转换，用于选择有用样本的时间窗口模块和数学变换模块，时间窗口模块将奈奇斯窗口类型的时间窗口应用于 非零滚降。

公开(公告)号：US08729015B2

公开(公告)日：2014-05-20

申请号：US12809397

申请日：2008-11-21

申请人： Joel Richard ,  Helen Baldascini ,  Rita Agostinetto ,  Luisa De Angelis ,  Frantz Deschamps

发明人： Joel Richard ,  Helen Baldascini ,  Rita Agostinetto ,  Luisa De Angelis ,  Frantz Deschamps

IPC分类号： A61K38/27 ,  A61K9/16 ,  C12M1/02 ,  C12M3/04

CPC分类号： A61K9/5015 ,  A61K9/127 ,  A61K38/27

摘要： The invention relates to growth hormone (GH) formulations having sustained-release properties, in particular human growth hormone (hGH) and methods for their preparation. The growth hormone formulations can be manufactured without denaturing of the protein and can conveniently be administrated to the person in need thereof by using a conventional syringe via a needle having a small diameter.

摘要翻译： 本发明涉及具有缓释性质的生长激素（GH）制剂，特别是人生长激素（hGH）及其制备方法。 可以在不使蛋白质变性的情况下制造生长激素制剂，并且可以通过使用具有小直径的针的常规注射器方便地向有需要的人施用生长激素制剂。

公开(公告)号：US08197392B2

公开(公告)日：2012-06-12

申请号：US12849389

申请日：2010-08-03

申请人： Ben Silverman ,  Joel Richard Grenz ,  Darren Shane

发明人： Ben Silverman ,  Joel Richard Grenz ,  Darren Shane

IPC分类号： A63B21/002 ,  A63B21/068

CPC分类号： A63B7/00 ,  A63B21/0023 ,  A63B21/16 ,  A63B21/1645 ,  A63B2023/006 ,  A63B2208/029 ,  A63B2225/09 ,  Y10S482/904

摘要： An exercise strap comprises an upper strap and a lower strap. A plurality of loop members are located on the lower strap to allow for handles to be easily removed and replaced on different locations on the lower strap. An adjustment member attached to both the upper strap and the lower strap allows for the overall length of the exercise strap to be adjusted. A strap attachment member attached to the upper strap connects the exercise strap to a suitable mounting mechanism.

摘要翻译： 运动皮带包括上带和下带。 多个环构件位于下带上，以允许手柄在下带上的不同位置容易地移除和更换。 附接到上带和下带的调节构件允许调整运动带的整个长度。 附接到上带的皮带附件将健身带连接到合适的安装机构。