STABILIZED MENTHOL AND OTHER VOLATILE COMPOUND COMPOSITIONS AND METHODS

    公开(公告)号:US20230226189A1

    公开(公告)日:2023-07-20

    申请号:US18124897

    申请日:2023-03-22

    摘要: The present disclosure relates to a stabilized or more stable volatile compound, e.g., menthol, compositions and methods of making and using them including a mixture of a stabilizer compound of formula (I), for example, undecylenic acid methyl ester, undecylenic acid or a salt thereof and a volatile compound where the volatile compound is less susceptible to volatizing into a gas.




    wherein A is —(CH2)a—CH═CH—(CH 2)5-a—H where a is from 0 to 5,
    —(CH2)b—CH═CH—(CH 2)6-b—H where b is from 0 to 6,
    —(CH2)c—CH═CH—(CH 2)7-c—H where c is from 0 to 7,
    —(CH2)d—CH═CH—(CH 2)8-d—H where d is from 0 to 8, or
    —CH2)e—CH═CH—(CH 2)9-d—H where d is from 0 to 9;
    B is hydrogen or C1-5 alkyl; and pharmaceutically acceptable salts thereof where B is hydrogen.