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    MONITORING DEVICE AND METHOD FOR ESTIMATING BLOOD CONSTITUENT CONCENTRATION FOR TISSUES WITH LOW PERFUSION
    3.
    发明申请
    MONITORING DEVICE AND METHOD FOR ESTIMATING BLOOD CONSTITUENT CONCENTRATION FOR TISSUES WITH LOW PERFUSION 有权
    用于估计具有低灌注性的组织的血液成分浓度的监测装置和方法

    公开(公告)号：US20120190948A1

    公开(公告)日：2012-07-26

    申请号：US13406691

    申请日：2012-02-28

    Applicant: Rolf Vetter ,  Leopoldo Rossini ,  Andrea Ridolfi ,  Josep Sola i Caros ,  Marc Correvon

    Inventor： Rolf Vetter ,  Leopoldo Rossini ,  Andrea Ridolfi ,  Josep Sola i Caros ,  Marc Correvon

    IPC: A61B5/0205 ,  A61B5/1455

    CPC classification number: A61B5/02405 ,  A61B5/0205 ,  A61B5/02416 ,  A61B5/0245 ,  A61B5/14552 ,  A61B5/721 ,  A61B5/7221 ,  A61B5/7257 ,  A61B2562/0219 ,  A61B2562/0233 ,  A61B2562/046

    Abstract: The present disclosure relates to a method for estimating blood constituent concentration of a user under low perfusion conditions using a spectrophotometry-based monitoring device; the method comprising: measuring a plurality of photoplethysmographic (PPG) signals; measuring a cardio-synchronous (CV) signal; detecting an instantaneous heart rate and determining a heart rate variability from the CV signal; selecting reliable projected PPG signals; estimating a value of said blood constituent concentration from the magnitude of said reliable projected PPG signals. The disclosed method requires diminished computational load compared to conventional methods based on frequency domain approach as FFT or DCT. The disclosure also pertains to a monitoring device for estimating blood constituent concentration in tissue under low perfusion of a user.

    Abstract translation: 本公开涉及一种使用基于分光光度法的监测装置在低灌注条件下估计使用者血液成分浓度的方法; 所述方法包括：测量多个光电容积描记（PPG）信号; 测量心电同步（CV）信号; 检测瞬时心率并从CV信号确定心率变异性; 选择可靠的投影PPG信号; 从所述可靠的投影PPG信号的大小估计所述血液成分浓度的值。 与基于频域方法的常规方法相比，所公开的方法需要减少的计算负载作为FFT或DCT。 本公开还涉及用于估计用户低灌注下组织中血液成分浓度的监测装置。

    Floating front-end amplifier and one-wire measuring devices
    5.
    发明授权
    Floating front-end amplifier and one-wire measuring devices 有权
    浮动前置放大器和单线测量装置

    公开(公告)号：US08427181B2

    公开(公告)日：2013-04-23

    申请号：US12919018

    申请日：2009-03-10

    Applicant: Olivier Chetelat ,  Josep Sola I Caros

    Inventor： Olivier Chetelat ,  Josep Sola I Caros

    IPC: G01R27/08

    CPC classification number: A61B5/0428 ,  A61B5/04004 ,  H03F3/45475

    Abstract: A follower amplifier with power supply biased by a controlled voltage source such that the power supply potentials are, for the frequencies of interest, as close as possible to the potential of the follower output. There is proposed a front-end electronic circuit for biopotential and impedance measurements with outstanding performances (very high input impedance and gain very close to unity). Preferably, the explicit guard electrode and the explicit electronic unit at the belt are no longer necessary; all electronics is embedded in units placed directly at the measurement sites. Moreover, the proposed front-end electronic circuit allows a drastic simplification of the cabling and connectors since all units are connected to only one wire (the theoretical minimum) for potential reference and current return. Preferably, this wire does not even require an electrical isolation and can be easily embedded in the textile of a shirt, in a garment, mesh, belt, etc.

    Abstract translation: 具有由受控电压源偏置的电源的跟随放大器，使得针对感兴趣的频率的电源电位尽可能接近跟随器输出的电位。 提出了一种用于生物电位和阻抗测量的前端电子电路，具有出色的性能（非常高的输入阻抗和增益非常接近于一体）。 优选地，不再需要在带上的显性保护电极和显式电子单元; 所有电子产品都嵌入直接放置在测量点的单元。 此外，所提出的前端电子电路允许电缆和连接器的大大简化，因为所有单元仅连接到一个导线（理论最小值），用于潜在的参考和电流返回。 优选地，该线材甚至不需要电隔离并且可以容易地嵌入到衣服，网状物，带等中的衬衫的纺织品中。

    FLOATING FRONT-END AMPLIFIER AND ONE-WIRE MEASURING DEVICES
    6.
    发明申请
    FLOATING FRONT-END AMPLIFIER AND ONE-WIRE MEASURING DEVICES 有权
    浮动前端放大器和单线测量装置

    公开(公告)号：US20110001497A1

    公开(公告)日：2011-01-06

    申请号：US12919018

    申请日：2009-03-10

    Applicant: Olivier CHETELAT ,  Josep SOLA I CAROS

    Inventor： Olivier CHETELAT ,  Josep SOLA I CAROS

    IPC: G01R27/08 ,  H03F1/00

    CPC classification number: A61B5/0428 ,  A61B5/04004 ,  H03F3/45475

    Abstract: A follower amplifier with power supply biased by a controlled voltage source such that the power supply potentials are, for the frequencies of interest, as close as possible to the potential of the follower output. There is proposed a front-end electronic circuit for biopotential and impedance measurements with outstanding performances (very high input impedance and gain very close to unity). Preferably, the explicit guard electrode and the explicit electronic unit at the belt are no longer necessary; all electronics is embedded in units placed directly at the measurement sites. Moreover, the proposed front-end electronic circuit allows a drastic simplification of the cabling and connectors since all units are connected to only one wire (the theoretical minimum) for potential reference and current return. Preferably, this wire does not even require an electrical isolation and can be easily embedded in the textile of a shirt, in a garment, mesh, belt, etc.

    Abstract translation: 具有由受控电压源偏置的电源的跟随放大器，使得针对感兴趣的频率的电源电位尽可能接近跟随器输出的电位。 提出了一种用于生物电位和阻抗测量的前端电子电路，具有出色的性能（非常高的输入阻抗和增益非常接近于一体）。 优选地，不再需要在带上的显性保护电极和显式电子单元; 所有电子产品都嵌入直接放置在测量点的单元。 此外，所提出的前端电子电路允许电缆和连接器的大大简化，因为所有单元仅连接到一个导线（理论最小值），用于潜在的参考和电流返回。 优选地，该线材甚至不需要电隔离并且可以容易地嵌入到衣服，网状物，带等中的衬衫的纺织品中。

    Method for Determining non-invasively a Heart-Lung Interaction
    7.
    发明申请
    Method for Determining non-invasively a Heart-Lung Interaction 审中-公开
    非侵入性确定心肺相互作用的方法

    公开(公告)号：US20140094664A1

    公开(公告)日：2014-04-03

    申请号：US14115384

    申请日：2012-05-02

    Applicant: Josep Sola i Caros ,  Josef X. Brunner

    Inventor： Josep Sola i Caros ,  Josef X. Brunner

    IPC: A61B5/0205 ,  A61B5/029 ,  A61B8/08 ,  A61B5/0402 ,  A61B7/04 ,  A61B5/021 ,  A61B5/00

    CPC classification number: A61B5/0205 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/02416 ,  A61B5/029 ,  A61B5/0402 ,  A61B5/0536 ,  A61B5/7257 ,  A61B7/04 ,  A61B8/08

    Abstract: The present disclosure concerns a method for determining a heart-lung interaction factor of a subject, comprising: measuring a heart activity-related signal comprising heart activity-related information; from the heart activity-related signal, calculating a frequency of cardiac cycle and a frequency of respiratory cycle; from the heart activity-related signal, determining a cardiac cycle energy at the frequency of cardiac cycle, determining a respiratory cycle energy at the frequency of respiratory cycle, and determining a heart-lung interaction energy at an intermodulation frequency corresponding to the difference between the frequency of respiratory cycle and the frequency of cardiac cycle, or the sum of the frequency of respiratory cycle and the frequency of cardiac cycle; and determining a heart-lung interaction factor from the ratio of the heart-lung interaction energy and one of the cardiac cycle energy and the respiratory cycle energy. The heart-lung interaction factor can be determined non-invasively.

    Abstract translation: 本公开涉及用于确定受试者的心肺相互作用因子的方法，包括：测量包括心脏活动相关信息的心脏活动相关信号; 从心脏活动相关信号，计算心脏周期的频率和呼吸周期的频率; 从所述心脏活动相关信号中确定心动周期频率处的心循环能量，确定呼吸周期频率处的呼吸循环能量，以及确定与所述心脏周期之间的差异相对应的互调频率处的心肺相互作用能量 呼吸周期的频率和心脏周期的频率，或呼吸周期的频率和心脏周期的频率之和; 以及根据心肺相互作用能量与心动周期能量与呼吸循环能量之间的比率确定心肺相互作用因子。 心肺相互作用因子可以非侵入性地确定。

    Method and apparatus for a continuous non-invasive and non-obstrusive monitoring of blood pressure
    8.
    发明授权
    Method and apparatus for a continuous non-invasive and non-obstrusive monitoring of blood pressure 有权
    用于连续非侵入性和非obstrusive监测血压的方法和装置

    公开(公告)号：US08585605B2

    公开(公告)日：2013-11-19

    申请号：US12341619

    申请日：2008-12-22

    Applicant: Josep Sola I Caros ,  Hans-Andrea Loeliger

    Inventor： Josep Sola I Caros ,  Hans-Andrea Loeliger

    IPC: A61B5/02

    CPC classification number: A61B5/029 ,  A61B5/02028 ,  A61B5/02125 ,  A61B5/0295 ,  A61B5/0402 ,  A61B5/0535 ,  G06F19/00

    Abstract: The invention provides a method and an apparatus for a continuous non-invasive and non-obstrusive monitoring of blood pressure. The method comprises the steps of: a) measuring the value (PW) of a Pulse Wave parameter, equal to or derived from the Pulse Wave Velocity (PWV) parameter of a segment of the arterial tree of a subject, b) measuring the value (CO) of the Cardiac Output parameter, and c) determining the value (BP) of the blood pressure that satisfies B ⁢ ⁢ P = arg ⁢ ⁢ min BP ⁢ ⁢ d ⁡ ( P ⁢ ⁢ W , ⁢ ( C ⁢ ⁢ O , B ⁢ ⁢ P ) ) , where PW is the value measured in step a), (CO, BP) corresponds to a predicted value of the Pulse Wave parameter computed according to a model of the segment of the arterial tree, the value (CO) of the Cardiac Output parameter measured in step b) and an hypothesized value of the blood pressure.

    Abstract translation: 本发明提供了一种用于连续非侵入性和非obstrusive监测血压的方法和装置。 该方法包括以下步骤：a）测量脉搏波参数的值（PW）等于或从主体动脉树段的脉搏波速度（PWV）参数导出，b）测量值 （CO），以及c）确定满足B笨P的血压值（BP）= arg······························ ，B笨P）），其中PW是步骤a）中测量的值，（CO，BP）对应于根据动脉树段的模型计算的脉搏波参数的预测值， CO）在步骤b）中测量的心输出参数和假设的血压值。

    DEVICE FOR MONITORING ARTERIAL OXYGEN SATURATION
    9.
    发明申请
    DEVICE FOR MONITORING ARTERIAL OXYGEN SATURATION 审中-公开
    用于监测氧化亚氮饱和度的装置

    公开(公告)号：US20080171926A1

    公开(公告)日：2008-07-17

    申请号：US11969962

    申请日：2008-01-07

    Applicant: Josep SOLA I CAROS ,  Christophe Verjus ,  Jens Krauss ,  Olivier Chetelat ,  Victor Neuman

    Inventor： Josep SOLA I CAROS ,  Christophe Verjus ,  Jens Krauss ,  Olivier Chetelat ,  Victor Neuman

    IPC: A61B5/1455

    CPC classification number: A61B5/14551 ,  A61B5/7207

    Abstract: The present invention concerns an optical based pulse oximetry device comprising: first, second and third light emitting means, for placement on the skin surface of a body part to inject light in a tissue of said part, the wavelengths of the light emitted by said second and third means being different from each other light detecting means located at a relatively short distance from said first light emitting means and at relatively long distance from said second light emitting means and said third light emitting means, for collecting at the skin surface light of said emitting means having travelled through said tissue, first computing means for denoising the output signals of said long distance light detecting means from the output signals of said short distance light detecting means, and second computing means for deriving oximetry measurements from the denoised output signals of said long distance light detecting means.

    Abstract translation: 本发明涉及一种基于光学的脉搏血氧饱和度测量装置，包括：第一，第二和第三发光装置，用于放置在身体部分的皮肤表面上，以将光注入所述部分的组织中，由所述第二 并且第三装置彼此不同，光检测装置位于距离所述第一发光装置相对较短的距离处并且与所述第二发光装置和所述第三发光装置相距较远的距离处，用于在皮肤表面收集所述第一发光装置的光 已经穿过所述组织的发射装置，用于从所述短距离光检测装置的输出信号中去除所述长距离光检测装置的输出信号的第一计算装置，以及用于从所述短距离光检测装置的去噪输出信号中导出血氧测定测量值的第二计算装置 长距离光检测装置。

    Identification of the presence of speech in digital audio data
    10.
    发明申请
    Identification of the presence of speech in digital audio data 失效
    识别数字音频数据中语音的存在

    公开(公告)号：US20050192795A1

    公开(公告)日：2005-09-01

    申请号：US11065555

    申请日：2005-02-24

    Applicant: Yin Lam ,  Josep Sola I Caros

    Inventor： Yin Lam ,  Josep Sola I Caros

    IPC: G10L25/78 ,  G11B7/00

    CPC classification number: G10L25/78 ,  G10H2210/046

    Abstract: The present invention provides a method, a computer-software-product and an apparatus for enabling a determination of speech related audio data within a record of digital audio data. The method comprises steps for extracting audio features from the record of digital audio data, for classifying one or more subsections of the record of digital audio data, and for marking at least a part of the record of digital audio data classified as speech. The classification of the digital audio data record is performed on the basis of the extracted audio features and with respect to at least one predetermined audio class. The extraction of the at least one audio feature as used by a method according to the invention comprises steps for partitioning the record of digital audio data into adjoining frames, defining a window for each frame which is formed by a sequence of adjoining frames containing the frame under consideration, determining for the frame under consideration and at least one further frame of the window a spectral-emphasis-value which is related to the frequency distribution contained in the digital audio data of the respective frame, and assigning a presence-of-speech indicator value to the frame under consideration based on an evaluation of the differences between the spectral-emphasis-values determined for the frame under consideration and at least one further frame of the window.

    Abstract translation: 本发明提供一种能够确定数字音频数据的记录内的语音相关音频数据的方法，计算机软件产品和装置。 该方法包括从数字音频数据的记录中提取音频特征的步骤，用于分类数字音频数据的记录的一个或多个子部分，以及标记被分类为语音的数字音频数据的记录的至少一部分。 数字音频数据记录的分类是根据所提取的音频特征和关于至少一个预定音频类进行的。 如根据本发明的方法使用的至少一个音频特征的提取包括将数字音频数据的记录划分成相邻帧的步骤，为由包含帧的相邻帧的序列形成的每个帧定义窗口 在考虑下，确定正在考虑的帧和窗口的至少一个另外的帧，与包含在各个帧的数字音频数据中的频率分布相关的频谱强调值，并且分配语音演讲 基于对所考虑的帧确定的频谱强调值与窗口的至少一个另外的帧之间的差异的评估，对正在考虑的帧的指示符值进行评估。

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