ANTI-ADHESION POLYMER COMPOSITION CAPABLE OF SUPPORTING GROWTH FACTOR
    1.
    发明申请
    ANTI-ADHESION POLYMER COMPOSITION CAPABLE OF SUPPORTING GROWTH FACTOR 有权
    抗粘合聚合物组合物可支持生长因子

    公开(公告)号:US20150010490A1

    公开(公告)日:2015-01-08

    申请号:US14374988

    申请日:2012-03-08

    IPC分类号: A61L24/04 A61L24/00 C08L71/02

    摘要: The present invention relates to an anti-adhesion polymer composition capable of supporting growth factor, which effectively exhibits anti-adhesion function and, at the same time, has an excellent adhesive property so as to be able to easily and continuously adhere to a wound site, has antibacterial and hemostatic properties, and is composed of an injectable formulation suitable for use in minimally invasive surgery, laparoscopic surgery or the like. The anti-adhesion polymer composition capable of supporting growth factor comprises: 24-50 wt % of a polyethyleneglycol-polypropyleneglycol-polyethyleneglycol (PEG-PPG-PEG) block copolymer having a polyethyleneglycol (PEG) content of 65-85 wt % and a molecular weight of 6,000-20,000 Da; 0.03-5 wt % of gelatin; 0.03-5 wt % of chitosan; and distilled water.

    摘要翻译: 本发明涉及一种能够有效显示抗粘连功能的支持生长因子的抗粘连聚合物组合物,同时具有优异的粘合性能,从而能够容易地并且连续地附着于伤口部位 具有抗菌和止血特性,并且由适用于微创手术,腹腔镜手术等的可注射制剂组成。 能够支持生长因子的抗粘连聚合物组合物包括:具有聚乙二醇(PEG)含量为65-85重量%的聚乙二醇 - 聚丙二醇 - 聚乙二醇(PEG-PPG-PEG)嵌段共聚物的24-50重量%和分子量 重量6,000-20,000 Da; 0.03-5重量%的明胶; 0.03-5重量%的壳聚糖; 和蒸馏水。