公开(公告)号：US07704692B1

公开(公告)日：2010-04-27

申请号：US11758288

申请日：2007-06-05

申请人： Hitoshi Iwahashi ,  Yuko Momose ,  Emiko Kitagawa ,  Junko Takahashi

发明人： Hitoshi Iwahashi ,  Yuko Momose ,  Emiko Kitagawa ,  Junko Takahashi

IPC分类号： C12Q1/64

CPC分类号： C12Q1/18

摘要： Biology-based processes for detecting toxic substances are provided. The processes comprise transforming cells with a vector comprising a polynucleotide which comprises a promoter of certain yeast gene operably linked to a polynucleotide encoding a marker protein; contacting the transformed cells to test sample; and detecting the expression of mRNA encoding the marker protein, thus detecting a toxic compound in the test sample.

摘要翻译： 提供了基于生物学检测有毒物质的方法。 该方法包括用包含多核苷酸的载体转化细胞，所述多核苷酸包含可操作地连接到编码标记蛋白的多核苷酸的某些酵母基因的启动子; 使转化的细胞接触测试样品; 并检测编码标记蛋白的mRNA的表达，从而检测测试样品中的有毒化合物。

公开(公告)号：US20070287155A1

公开(公告)日：2007-12-13

申请号：US11772057

申请日：2007-06-29

申请人： Hitoshi IWAHASHI ,  Yuko Momose ,  Emiko Kitagawa ,  Junko Takahashi

发明人： Hitoshi IWAHASHI ,  Yuko Momose ,  Emiko Kitagawa ,  Junko Takahashi

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6876 ,  C12Q2600/158

摘要： Biology-based processes for detecting toxic substances are provided. The processes comprise detecting mRNA that is expressed in the presence of toxic substances by a cell comprising a yeast gene as followed, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof.

摘要翻译： 提供了基于生物学检测有毒物质的方法。 该方法包括检测由含有如下酵母基因的细胞存在的有毒物质所表达的mRNA，或与酵母基因同源且源于其他物种的基因，其中mRNA对应于所述酵母基因或 其同源基因。

公开(公告)号：US20050013021A1

公开(公告)日：2005-01-20

申请号：US10862908

申请日：2004-06-08

申请人： Koichi Takahashi ,  Junko Takahashi

发明人： Koichi Takahashi ,  Junko Takahashi

IPC分类号： G02B17/06 ,  G02B17/08 ,  G02B17/00

CPC分类号： G02B17/0896 ,  G02B17/0642 ,  G02B17/0663 ,  G02B17/0694 ,  G02B17/0816 ,  G02B17/0832 ,  G02B17/0848

摘要： The decentered optical system is configured by a first, a second and a third reflecting mirror disposed decentered, a focusing device, and a light receiver. The optical path is folded by the first, second, and third reflecting mirrors, aberration correction is carried out by a rotationally asymmetric reflecting surface, and an intermediate image is formed between the second and third reflecting mirrors and another reflecting mirror. The reflected light of the third reflecting mirror is made to form a substantially parallel light beam that forms an exit pupil. An image is formed on the light receiving surface by the focusing device. This decentered optical system is used in a light transmitting device, a light receiving device, and a light transmitting and receiving system, and carries out light tracking by detecting the position of the received light image.

摘要翻译： 偏心光学系统由偏心设置的第一，第二和第三反射镜，聚焦装置和光接收器构成。 光路被第一，第二和第三反射镜折叠，通过旋转非对称反射表面进行像差校正，并且在第二和第三反射镜和另一反射镜之间形成中间图像。 使第三反射镜的反射光形成基本上平行的形成出射光瞳的光束。 通过聚焦装置在光接收表面上形成图像。 该偏心光学系统用于光发射装置，光接收装置和光发射和接收系统中，并且通过检测接收的光图像的位置来执行光跟踪。

公开(公告)号：US6097354A

公开(公告)日：2000-08-01

申请号：US84492

申请日：1998-05-27

申请人： Koichi Takahashi ,  Junko Takahashi

发明人： Koichi Takahashi ,  Junko Takahashi

IPC分类号： G02B13/18 ,  G02B25/00 ,  G02B27/00 ,  G02B27/01 ,  G02B27/02 ,  H04N5/64 ,  G09G5/00 ,  G02B27/14

CPC分类号： G02B27/0172 ,  G02B2027/011 ,  G02B2027/0178

摘要： An image display apparatus capable of providing a clear observation image at a wide field angle by using an ocular optical system including an optical element having a minimal number of constituent surfaces. The apparatus includes an image display device (5) which displays an image, and an ocular optical system (4) which projects the image formed by the image display device (5) and leads the image to an observer's eyeball (3). The ocular optical system (4) has two surfaces, i.e. a first surface (11) and a second surface (12). A space formed by the two surfaces is filled with a medium having a refractive index larger than 1. At least one surface of the ocular optical system (4) is a non-rotationally symmetric aspherical surface decentered or tilted with respect to an observer's visual axis (2). The first surface (11) is a transmitting surface which serves as both an entrance surface for light rays emitted from the image display device (5) and an exit surface through which the light rays exit from the ocular optical system (4). The first surface (11) is convex toward the observer.

摘要翻译： 一种图像显示装置，其能够通过使用包括具有最小数量的构成表面的光学元件的眼睛光学系统，以广角度提供清晰的观察图像。 该装置包括显示图像的图像显示装置（5）和投射由图像显示装置（5）形成的图像并将图像引导到观察者眼球（3）的眼睛光学系统（4）。 眼睛光学系统（4）具有两个表面，即第一表面（11）和第二表面（12）。 由两个表面形成的空间填充有折射率大于1的介质。目镜光学系统（4）的至少一个表面是相对于观察者视轴偏心或倾斜的非旋转对称非球面表面 （2）。 第一表面（11）是用于从图像显示装置（5）发射的光线的入射面和光线从眼睛光学系统（4）射出的出射面的透射面。 第一表面（11）朝向观察者凸出。

公开(公告)号：US5986812A

公开(公告)日：1999-11-16

申请号：US896856

申请日：1997-07-18

申请人： Junko Takahashi

发明人： Junko Takahashi

IPC分类号： G02B27/02 ,  G02B27/00 ,  G02B27/01 ,  H04N5/64 ,  G02B27/14

CPC分类号： G02B27/0172 ,  G02B2027/011 ,  G02B2027/0178

摘要： A head-mounted image display apparatus capable of providing an observation image which is clear and has minimal distortion even at a wide field angle. Display light from an image display device (7) enters an optical system (8) through a first surface (3) serving as both transmitting and reflecting surfaces. The incident light is reflected by a third surface (5) and further reflected by the first surface (3). Then, the reflected light is reflected by a second surface 4 which is a decentered reflecting surface disposed on an optical axis (2) to face an exit pupil (1). The reflected light exits from the optical system (8) through the first surface (3), travels along the optical axis (2) and enters an observer's pupil placed at the exit pupil (1), without forming an intermediate image, thus forming a display image on the retina of the observer's eye. The first to third surfaces (3 to 5) are each formed from a plane-symmetry three-dimensional surface having no axis of rotational symmetry in nor out of the surface and having only one plane of symmetry.

摘要翻译： 一种头戴式图像显示装置，能够提供清晰的观察图像，即使在宽视角下也具有最小失真。 来自图像显示装置（7）的显示光通过用作透射和反射表面的第一表面（3）进入光学系统（8）。 入射光被第三表面（5）反射并进一步被第一表面（3）反射。 然后，反射光被设置在光轴（2）上的面对出射光瞳（1）的偏心反射面的第二面4反射。 反射光通过第一表面（3）从光学系统（8）射出，沿着光轴（2）行进并进入放置在出射光瞳（1）处的观察者瞳孔，而不形成中​​间图像，从而形成 在观察者眼睛的视网膜上显示图像。 第一至第三表面（3至5）各自由不具有旋转对称轴的平面对称三维表面形成，并且仅具有一个对称平面。

公开(公告)号：US5909317A

公开(公告)日：1999-06-01

申请号：US822554

申请日：1997-03-19

申请人： Masaya Nakaoka ,  Takayoshi Togino ,  Junko Takahashi

发明人： Masaya Nakaoka ,  Takayoshi Togino ,  Junko Takahashi

IPC分类号： H04N5/64 ,  G02B27/00 ,  G02B27/01 ,  G02B27/14

CPC分类号： G02B27/0025 ,  G02B27/0172 ,  G02B2027/011 ,  G02B2027/0132 ,  G02B2027/0178

摘要： An image display apparatus corrected for distortions, particularly, a distortion which is asymmetric with respect to the center of the image field. The apparatus includes an image display device (8), and an ocular optical system (42) having a rotationally asymmetric optical surface or a decentered optical surface having a power. The apparatus satisfies the condition of .vertline.tan .THETA..sub.1 -tan .THETA..sub.2 .vertline./tan .THETA..sub.1

摘要翻译： 校正了失真的图像显示装置，特别是相对于图像场的中心是不对称的失真。 该装置包括图像显示装置（8）和具有旋转非对称光学表面的眼睛光学系统（42）或具有电力的偏心光学表面。 该装置满足| tan THETA 1-tan THETA 2 | / tan THETA 1 <0.1的条件，其中THETA 1是从图像显示装置（8）上的任意点（44）发射的光线和 穿过出射光瞳（40）的中心和视轴（41），即连接观察者瞳孔的中心和图像显示装置（8）的投影图像的中心的直线，以及THETA 2是在视轴（41）和从与图像显示器的图像显示面的中心（43）的任意点（44）对称点的点（45）发射的光线之间形成的角度 装置（8）并穿过出射光瞳（40）的中心。

公开(公告)号：US5774268A

公开(公告)日：1998-06-30

申请号：US733647

申请日：1996-10-17

申请人： Junko Takahashi

发明人： Junko Takahashi

IPC分类号： G02B27/02 ,  G02B27/00 ,  G02B27/01 ,  G09F9/00 ,  H04N5/64 ,  G02B27/14

CPC分类号： G02B27/0172 ,  G02B2027/011 ,  G02B2027/0178

摘要： A compact, wide-field, high-resolution, low-cost and easy-to-handle head- or face-mounted image display apparatus in which unwanted light is reduced without using a polarizing member or a louver optical system. The apparatus has an image display device (1) for displaying an image; an optical system (P) for projecting the image into an observer's eyeball as an enlarged image without effecting image formation on the way to the observer's eyeball; and a device for mounting and retaining the image display device (1) and the optical system (P) on an observer's head or face i The optical system (P) is a prism optical system which has at least four surfaces, that is, a back-coated mirror (3) of positive power which is disposed to face the image display device (1), an image display device-side surface (2) facing opposite to the back-coated mirror (3), an exit surface (5) closer to the observer's eyeball, and a transmitting surface (7) facing opposite to the exit surface (5), and which is made of a transparent medium having a refractive index larger than 1. The distance between the vertex of the back-coated mirror (3) and the vertex of the image display device-side surface (2) satisfies the condition of 0.8.ltoreq..theta..sub.min /.theta..sub.max .ltoreq.1.5.

摘要翻译： 紧凑，宽场，高分辨率，低成本和易于处理的头戴式或面部安装的图像显示装置，其中不使用偏光构件或百叶窗光学系统而减少不需要的光。 该装置具有用于显示图像的图像显示装置（1） 用于将图像投影到观察者的眼球中作为放大图像的光学系统（P），而不会在到达观察者眼球的途中影像形成; 以及用于将图像显示装置（1）和光学系统（P）安装并保持在观察者头部或面部i上的装置。光学系统（P）是具有至少四个表面的棱镜光学系统，即， 设置为面对图像显示装置（1）的正面功率的背面镜（3），与背面镜（3）相对的图像显示装置侧面（2），出射面（5） ）和与出射表面（5）相对的透射表面（7），并且由折射率大于1的透明介质制成。背涂层的顶点之间的距离 反射镜（3）和图像显示装置侧表面（2）的顶点满足0.8

公开(公告)号：US08192962B2

公开(公告)日：2012-06-05

申请号：US12554386

申请日：2009-09-04

申请人： Hitoshi Iwahashi ,  Yuko Momose ,  Emiko Kitagawa ,  Junko Takahashi

发明人： Hitoshi Iwahashi ,  Yuko Momose ,  Emiko Kitagawa ,  Junko Takahashi

IPC分类号： C12P19/34 ,  C12Q1/68

CPC分类号： C12Q1/6876 ,  C12Q2600/158

摘要： Biology-based processes for detecting toxic substances are provided. The processes comprise detecting mRNA that is expressed in the presence of toxic substances by a cell comprising a yeast gene as followed, or a gene that is homologous to the yeast genes and is derived from other species, wherein the mRNA corresponds to said yeast gene or said homologous gene thereof.

摘要翻译： 提供了基于生物学检测有毒物质的方法。 该方法包括检测由含有如下酵母基因的细胞存在的有毒物质所表达的mRNA，或与酵母基因同源且源于其他物种的基因，其中mRNA对应于所述酵母基因或 所述同源基因。

公开(公告)号：US20070034269A1

公开(公告)日：2007-02-15

申请号：US10574200

申请日：2004-10-01

申请人： Hidenori Nagai ,  Shinichi Wakida ,  Junko Takahashi

发明人： Hidenori Nagai ,  Shinichi Wakida ,  Junko Takahashi

IPC分类号： F15C1/04

CPC分类号： G01N27/44791 ,  B01J19/0093 ,  B01J2219/00837 ,  B01J2219/00934 ,  B01J2219/00943 ,  B01J2219/00984 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502738 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/165 ,  B01L2400/0622 ,  B01L2400/0688 ,  F16K99/0001 ,  F16K99/0017 ,  F16K99/0034 ,  F16K99/004 ,  Y10T137/2191

摘要： There is provided a method of controlling a flow of a fluid in a microchannel, in which a part of a surface of the microchannel is a hydrophilization portion comprised of a substance being capable of decreasing a contact angle of water by irradiation of light, and the method comprises (1) irradiating the hydrophilization portion with light to decrease a contact angle of water of its surface (hydrophilization step), (2) releasing a substance for increasing a contact angle of water from a material for controlling a contact angle of water which contains the substance for increasing a contact angle of water which provides a surface having a contact angle of water larger than that of the hydrophilization portion after the decreasing of a contact angle of water (releasing step), and (3) bringing the released substance for increasing a contact angle of water into contact with the surface of the hydrophilization portion to adhere the substance for increasing a contact angle of water to the surface, thereby increasing the contact angle of water of the surface of the hydrophilization portion (hydrophobilization step). Also there is provided a valve utilizing the mentioned method. Thus, there are provided a fluid control method and valve which enable hydrophobilization and hydrophilization to be easily carried out in a noncontact manner in a microchannel without using a moving part.

摘要翻译： 提供了一种控制微通道中的流体流动的方法，其中微通道的一部分表面是由能够通过照射光而降低水的接触角的物质的亲水化部分， 方法包括：（1）用光照射亲水化部分以降低其表面的水的接触角（亲水化步骤），（2）释放用于增加水的接触角的物质与用于控制水的接触角的材料 含有用于增加水的接触角的物质，其在水的接触角降低之后（释放步骤）提供具有大于亲水化部分的接触角的表面的表面，和（3）将释放的物质用于 增加水与亲水化部分表面接触的接触角，以粘附物质以增加水的接触角 从而增加亲水部分表面的水的接触角（疏水化步骤）。 还提供了利用所述方法的阀。 因此，提供一种流体控制方法和阀，其能够使疏水化和亲水化容易地以非接触的方式在微通道中进行而不使用移动部件。

公开(公告)号：US6097542A

公开(公告)日：2000-08-01

申请号：US951044

申请日：1997-10-15

申请人： Junko Takahashi ,  Koichi Takahashi

发明人： Junko Takahashi ,  Koichi Takahashi

IPC分类号： G02B27/02 ,  G02B27/00 ,  G02B27/01 ,  G09F9/00 ,  H04N5/64 ,  G02B27/14

CPC分类号： G02B27/0172 ,  G02B2027/011 ,  G02B2027/0178

摘要： An optical system for use, for example, in a head-mounted image display apparatus, which provides an observation image that is clear and has minimal distortion even at a wide field angle. The head-mounted image display apparatus has an image display device (6), and an optical system (9) that leads an image formed by the image display device (6) to an observer's eyeball position (1), without forming an intermediate image, so that the image can be observed as a virtual image. The optical system (9) includes a reflecting surface (4) performing only one reflection, and one or two transmitting surfaces (3). The space between the reflecting surface (4) and the transmitting surfaces (3) is filled with a medium having a refractive index larger than 1. At least the reflecting surface (4) is a non-rotationally symmetric surface configuration having no axis of rotational symmetry in nor out of the surface.

摘要翻译： 一种用于例如在头戴式图像显示装置中使用的光学系统，其提供即使在宽视场角下也是清晰且具有最小失真的观察图像。 头戴式图像显示装置具有图像显示装置（6）和将由图像显示装置（6）形成的图像引导到观察者的眼球位置（1）的光学系统（9），而不形成中​​间图像 ，使得可以将图像视为虚像。 光学系统（9）包括仅执行一个反射的反射表面（4）和一个或两个透射表面（3）。 反射面（4）与透射面（3）之间的空间用折射率大于1的介质填充。至少反射面（4）是不具有旋转轴的非旋转对称的表面构造 对称或不在表面。