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公开(公告)号:US20080319529A1
公开(公告)日:2008-12-25
申请号:US11935459
申请日:2007-11-06
申请人: Michael Krivoruchko , Matthew Birdsall , Gianfranco Pellegrini , Justin Goshgarian , Jeffrey Allen
发明人: Michael Krivoruchko , Matthew Birdsall , Gianfranco Pellegrini , Justin Goshgarian , Jeffrey Allen
IPC分类号: A61F2/06
CPC分类号: A61F2/88 , A61F2/915 , A61F2002/91508 , A61F2002/91558 , A61F2220/0058 , A61F2250/0036
摘要: A stent includes a central portion having a first waveform. The first waveform is wrapped around a longitudinal axis of the stent at a pitch to define a plurality of helical turns. The stent also includes an end segment connected to one end of the central portion. The end segment has a second waveform that includes a plurality of struts and a plurality of crowns. Each of the plurality of struts has a different length so that peaks of the crowns that define an end of the stent lie within a plane that is substantially perpendicular to the longitudinal axis. Cross-sectional areas of the struts having different lengths vary so that the struts move substantially uniformly during radial contraction and/or radial expansion of the stent.
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公开(公告)号:US20070244544A1
公开(公告)日:2007-10-18
申请号:US11279769
申请日:2006-04-14
申请人: Matthew Birdsall , Mark Dolan , Justin Goshgarian , Michael Krivoruchko , Joseph Lessar , Darrel Untereker , Peter Urbanski
发明人: Matthew Birdsall , Mark Dolan , Justin Goshgarian , Michael Krivoruchko , Joseph Lessar , Darrel Untereker , Peter Urbanski
CPC分类号: A61F2/2412 , A61F2/2418 , A61F2/2433 , A61F2002/9528 , A61F2210/0061 , A61F2250/006 , A61F2250/0069 , A61L24/0031 , A61L24/08 , C08L5/08
摘要: A valve replacement system that can be used for treating abnormalities of the right ventricular outflow tract includes a prosthetic valve device having a sealant contacting at least a portion of the outer surface of the valve device. The sealant may be breakable, and may be a hydrogel, an expandable hydrogel, or a solid. One embodiment of the invention includes a flowable sealant that is injected within the vascular system. Another embodiment of the invention includes a method for replacing a pulmonary valve that includes forming a seal around the exterior surface of a replacement valve and preventing blood flow around the replacement valve.
摘要翻译: 可用于治疗右心室流出道异常的瓣膜置换系统包括具有与阀装置的外表面的至少一部分接触的密封剂的人造瓣膜装置。 密封剂可以是可破裂的,并且可以是水凝胶,可膨胀水凝胶或固体。 本发明的一个实施方案包括注射在血管系统内的可流动的密封剂。 本发明的另一个实施例包括一种用于替换肺动脉瓣的方法,该方法包括在置换瓣膜的外表面周围形成密封并防止置换瓣膜周围的血液流动。
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公开(公告)号:US07318837B2
公开(公告)日:2008-01-15
申请号:US11278052
申请日:2006-03-30
申请人: Michael Krivoruchko , Joseph Lessar , Richard Francis , Matthew Birdsall , Darrel Untereker , Jeffrey Allen
发明人: Michael Krivoruchko , Joseph Lessar , Richard Francis , Matthew Birdsall , Darrel Untereker , Jeffrey Allen
IPC分类号: A61F2/06
CPC分类号: A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91541 , A61F2002/91558 , A61F2230/0013 , A61L31/022
摘要: A balloon-expandable stent formed from a customized alloy formulation. The stent alloy has a either a high, variable or no work hardening rate, very high modulus of elasticity (Young's modulus), and a low yield point. A stent constructed of a material with this combination of properties undergoes significant plastic deformation upon deployment in vivo to its implantation diameter and exhibits minimum recoil for better sizing. The plastic deformation also raises the subsequent yield point of the stent material resulting in a stronger stent upon implantation that is more resistant to vascular loading.
摘要翻译: 由定制的合金制剂形成的球囊扩张支架。 支架合金具有高的,可变的或没有加工硬化率,非常高的弹性模量(杨氏模量)和低屈服点。 由具有这种性质组合的材料构成的支架在体内部署到其植入直径时经历显着的塑性变形,并且显示出最小的反冲以获得更好的上浆。 塑性变形也提高了支架材料的随后屈服点,从而导致植入时更坚固的支架,其更能抵抗血管负荷。
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公开(公告)号:US20080147175A1
公开(公告)日:2008-06-19
申请号:US11611533
申请日:2006-12-15
IPC分类号: A61F2/06
CPC分类号: A61L31/022 , A61L31/128 , A61L31/148
摘要: A bioresorbable endoluminal prosthesis for placement in a body lumen having a stent substrate of a first metallic material that has a lower electrical potential than a standard reference electrode. The stent substrate is coated with a biodegradable polymer having a second metallic material dispersed therein, wherein the second metallic material has a higher electrical potential than the standard reference electrode. After implantation of the stent within the body lumen, the second metallic material is present in the polymeric coating in a sufficient concentration to cause galvanic corrosion of the first metallic material such that over time the stent substrate is bioresorbed.
摘要翻译: 一种生物可再吸收的腔内假体,用于放置在具有比标准参考电极具有更低电位的第一金属材料的支架基底的体腔内。 所述支架基底涂覆有分散在其中的第二金属材料的可生物降解的聚合物,其中所述第二金属材料具有比所述标准参比电极更高的电位。 在将支架植入体腔内之后,第二金属材料以足够的浓度存在于聚合物涂层中,以引起第一金属材料的电化学腐蚀,使得随着时间的推移,支架基底被生物吸收。
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公开(公告)号:US08623079B2
公开(公告)日:2014-01-07
申请号:US13093305
申请日:2011-04-25
IPC分类号: A61F2/24
CPC分类号: A61F2/24 , A61F2/2418 , A61F2/848 , A61F2002/8483 , A61F2220/0016 , A61F2230/0054 , A61F2230/008
摘要: A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.
摘要翻译: 一种支架式阀,包括具有大致管状主体部分,内部区域,纵向轴线,第一端部,第二端部和外部表面的支架结构; 至少一个流出倒钩,其从所述支架的外表面邻近所述支架结构的所述第一端延伸并朝向所述支架结构的第二端; 至少一个流入倒钩,其从所述支架的外表面延伸到所述支架结构的第二端并朝向所述支架结构的第一端; 以及附接在支架结构的内部区域内的阀结构。
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公开(公告)号:US20110264196A1
公开(公告)日:2011-10-27
申请号:US13093305
申请日:2011-04-25
CPC分类号: A61F2/24 , A61F2/2418 , A61F2/848 , A61F2002/8483 , A61F2220/0016 , A61F2230/0054 , A61F2230/008
摘要: A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.
摘要翻译: 一种支架式阀,包括具有大致管状主体部分,内部区域,纵向轴线,第一端部,第二端部和外部表面的支架结构; 至少一个流出倒钩,其从所述支架的外表面邻近所述支架结构的所述第一端延伸并朝向所述支架结构的第二端; 至少一个流入倒钩,其从所述支架的外表面延伸到所述支架结构的第二端并朝向所述支架结构的第一端; 以及附接在支架结构的内部区域内的阀结构。
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公开(公告)号:US07955383B2
公开(公告)日:2011-06-07
申请号:US11380134
申请日:2006-04-25
IPC分类号: A61F2/06
CPC分类号: A61L31/082
摘要: A laminated stent encapsulated with a metal coating is provided. The metal coating may be a very thin metal coating. Portions of the metal coating may be removed such that the metal coating covers voids in the laminate, particularly in the area where the different layers of the laminated stent come together. The metal coating for the laminated stent may be provided by sputtering, such as vacuum deposition or ion beam sputtering, spraying, dipping, or other known methods.
摘要翻译: 提供了用金属涂层包封的层压支架。 金属涂层可以是非常薄的金属涂层。 可以去除金属涂层的一部分,使得金属涂层覆盖层压体中的空隙,特别是在层压支架的不同层聚集在一起的区域中。 用于层压支架的金属涂层可以通过诸如真空沉积或离子束溅射,喷涂,浸渍或其它已知方法的溅射来提供。
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公开(公告)号:US20070250158A1
公开(公告)日:2007-10-25
申请号:US11380134
申请日:2006-04-25
IPC分类号: A61F2/06
CPC分类号: A61L31/082
摘要: A laminated stent encapsulated with a metal coating is provided. The metal coating may be a very thin metal coating. Portions of the metal coating may be removed such that the metal coating covers voids in the laminate, particularly in the area where the different layers of the laminated stent come together. The metal coating for the laminated stent may be provided by sputtering, such as vacuum deposition or ion beam sputtering, spraying, dipping, or other known methods.
摘要翻译: 提供了用金属涂层包封的层压支架。 金属涂层可以是非常薄的金属涂层。 可以去除金属涂层的一部分,使得金属涂层覆盖层压体中的空隙,特别是在层压支架的不同层聚集在一起的区域中。 用于层压支架的金属涂层可以通过诸如真空沉积或离子束溅射,喷涂,浸渍或其它已知方法的溅射来提供。
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公开(公告)号:US20080208352A1
公开(公告)日:2008-08-28
申请号:US11679426
申请日:2007-02-27
IPC分类号: A61F2/86
CPC分类号: A61L31/022 , A61F2/91 , A61F2/915 , A61F2002/91558 , A61F2230/0013 , A61F2250/0023 , A61L31/146
摘要: An endoluminal prosthesis for placement in a body lumen of a metallic material having controlled porosity for improved ductility. The metallic material may be formed into a stent structure or a wire or sheet, which may then be formed into the stent structure. The porous network of the stent includes pores that range from nanometer scale to micron scale. The controlled porosity accommodates volume changes as well as provides a barrier to crack propagation to allow alloy steels and amorphous metal materials, which would otherwise be considered too brittle for the demands of intraventional use, to be utilized in a stent.
摘要翻译: 用于放置在具有受控孔隙度的金属材料的体腔中用于改善延展性的腔内假体。 金属材料可以形成为可以形成支架结构的支架结构或线或片。 支架的多孔网络包括范围从纳米级到微米级的孔。 受控的孔隙率适应体积变化,并且提供裂纹扩展的障碍,以允许在支架中使用合金钢和非晶态金属材料,否则其将被认为对于常规使用的要求太脆。
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公开(公告)号:US20070233231A1
公开(公告)日:2007-10-04
申请号:US11278052
申请日:2006-03-30
申请人: Michael Krivoruchko , Joseph Lessar , Richard Francis , MATHEW BIRDSALL , JEFFREY ALLEN , DARREL UNTEREKER
发明人: Michael Krivoruchko , Joseph Lessar , Richard Francis , MATHEW BIRDSALL , JEFFREY ALLEN , DARREL UNTEREKER
IPC分类号: A61F2/94
CPC分类号: A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91541 , A61F2002/91558 , A61F2230/0013 , A61L31/022
摘要: A balloon-expandable stent formed from a customized alloy formulation. The stent alloy has a either a high, variable or no work hardening rate, very high modulus of elasticity (Young's modulus), and a low yield point. A stent constructed of a material with this combination of properties undergoes significant plastic deformation upon deployment in vivo to its implantation diameter and exhibits minimum recoil for better sizing. The plastic deformation also raises the subsequent yield point of the stent material resulting in a stronger stent upon implantation that is more resistant to vascular loading.
摘要翻译: 由定制的合金制剂形成的球囊扩张支架。 支架合金具有高的,可变的或没有加工硬化率,非常高的弹性模量(杨氏模量)和低屈服点。 由具有这种性质组合的材料构成的支架在体内部署到其植入直径时经历显着的塑性变形,并且显示出最小的反冲以获得更好的上浆。 塑性变形也提高了支架材料的随后屈服点,从而导致植入时更坚固的支架,其更能抵抗血管负荷。
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