公开(公告)号：US20080214447A1

公开(公告)日：2008-09-04

申请号：US11719921

申请日：2005-11-21

申请人： Motoo Kobayashi ,  Satoshi Sasamura ,  Hideyuki Muramatsu ,  Yasuhisa Tsurumi ,  Shigehiro Takase ,  Kazuki Okada

发明人： Motoo Kobayashi ,  Satoshi Sasamura ,  Hideyuki Muramatsu ,  Yasuhisa Tsurumi ,  Shigehiro Takase ,  Kazuki Okada

IPC分类号： A61K38/12 ,  C07K7/64 ,  A61P31/12 ,  C12P21/04

CPC分类号： C07K7/645

摘要： A cyclic peptide compound of the following general formula (I): Wherein R1, R2 and R3 are defined in the description, or a salt thereof. The compound (I) is useful for the prophylactic and/or therapeutic treatment of hepatitis C.

摘要翻译： 下列通式（I）的环肽化合物：其中R 1，R 2和R 3 3定义在说明书中，或 其盐。 化合物（I）可用于预防和/或治疗丙型肝炎。

公开(公告)号：US06254658B1

公开(公告)日：2001-07-03

申请号：US09256207

申请日：1999-02-24

申请人： Toshiyuki Taniuchi ,  Kazuki Okada ,  Kazuhiro Akiyama

发明人： Toshiyuki Taniuchi ,  Kazuki Okada ,  Kazuhiro Akiyama

IPC分类号： C22C2908

CPC分类号： C22C29/08 ,  B22F2005/001 ,  B22F2998/00 ,  B22F2998/10 ,  B22F2999/00 ,  C22C1/053 ,  B22F1/0018 ,  B22F9/04 ,  B22F1/0003 ,  B22F9/24

摘要： To provide a cemented carbide cutting tool having high chipping resistance. In a cutting tool made of a cemented carbide alloy comprising 8 to 13 percent by weight of Co; the Co based alloy containing W and C components as constituents for forming a dispersing phase, a V component, and an optional Cr component, and forming a binding phase; the residual dispersing phase having an average particle diameter of 1 &mgr;m or less; the alloy further containing 72 to 90 percent by area of WC according to measurement of an electron microscopic texture and fine (V,W)C or fine (V,Cr,W)C; each of the contents of the V and Cr components being 0.1 to 2 percent by weight of the total; the tungsten carbide as a constituent of the dispersing phase has a texture in which ultra-fine particles having a particle diameter of 100 nm or less of the Co-based cemented carbide alloy are dispersed in a tungsten carbide matrix.

摘要翻译： 提供具有高耐切割性的硬质合金切削工具。在由包含8至13重量％的Co的硬质合金制成的切削工具中， 含有W和C成分的Co基合金作为形成分散相的成分，V成分和任选的Cr成分，形成结合相。 残留分散相的平均粒径为1μm以下; 根据电子显微纹理和微细（V，W）C或细（V，Cr，W）C的测量，合金还含有72-90％的WC面积; V和Cr成分的含量分别为总量的0.1〜2重量％ 作为分散相的成分的碳化钨具有将Co系硬质合金合金的粒径为100nm以下的超微粒子分散在碳化钨基体中的结构。

公开(公告)号：US20120018129A1

公开(公告)日：2012-01-26

申请号：US13258022

申请日：2009-03-26

申请人： Takahiro Ushijima ,  Ryo Oya ,  Kazuki Okada

发明人： Takahiro Ushijima ,  Ryo Oya ,  Kazuki Okada

IPC分类号： F28D15/00 ,  F15D1/00 ,  B21D53/02 ,  F28D1/00

CPC分类号： F24D3/082 ,  F24D3/1066 ,  F24D3/18 ,  F24D12/02 ,  F24D19/1024 ,  F24D19/1039 ,  F24D19/1066 ,  F24D19/1072 ,  F24D2200/08 ,  F24D2200/12 ,  F24D2220/2009 ,  F24D2220/2081 ,  Y02B30/12 ,  Y02B30/14 ,  Y10T29/4935 ,  Y10T137/0318 ,  Y10T137/6579

摘要： It is aimed to simultaneously supply hot water at a required temperature to a high-temperature heating appliance and hot water at a required temperature to a low-temperature heating appliance, the low-temperature heating appliance requiring hot water at a temperature lower than a temperature required by the high-temperature heating appliance, and to enhance efficiency by collecting surplus heat when the temperature of the hot water to be supplied to the low-temperature heating appliance is adjusted. A pipe through which flows the hot water at a high temperature to be supplied to the high-temperature heating appliance is branched into a first supply pipe and a second supply pipe. Heat exchange is effected between the hot water flowing through the first supply pipe and return water which has been supplied to a first appliance. The first supply pipe and the second supply pipe are joined again, so that the hot water which has flowed through the first supply pipe and the hot water which has flowed through the second supply pipe are mixed and supplied to the low-temperature heating appliance.

摘要翻译： 目的在于将所需温度的热水同时向低温加热器具供给高温加热器具和所需温度的热水，低温加热器具需要温度低于温度的温水 高温加热器具所需的温度，并且当调节供给到低温加热器具的热水的温度时，通过收集多余的热量来提高效率。 将供给高温加热器具的高温热水流过的管分支为第一供给管和第二供给管。 在流过第一供应管的热水和已经供应到第一器具的回水之间进行热交换。 第一供给管和第二供给管再次接合，使流过第一供给管的热水和流过第二供给管的热水混合并供给到低温加热器具。

公开(公告)号：US08020393B2

公开(公告)日：2011-09-20

申请号：US12360439

申请日：2009-01-27

申请人： Kazuki Okada ,  Takahiro Ushijima ,  Kengo Takahashi

发明人： Kazuki Okada ,  Takahiro Ushijima ,  Kengo Takahashi

IPC分类号： F25B49/02 ,  F25B41/04

CPC分类号： F25B13/00 ,  F25B1/10 ,  F25B40/00 ,  F25B49/027 ,  F25B2341/0653 ,  F25B2341/066 ,  F25B2400/053 ,  F25B2400/054 ,  F25B2400/13 ,  F25B2400/16 ,  F25B2600/17 ,  F25B2600/21 ,  F25B2600/2509 ,  F25B2600/2513 ,  F25B2700/1931 ,  F25B2700/21174 ,  Y02B30/72

摘要： A heat pump type hot water supply outdoor apparatus, in a compressor, a water heat exchanger, a first expansion valve, a medium pressure receiver, a second expansion valve, and an air heat exchanger are connected circularly, has an injection circuit, which is a bypass for a part of the refrigerant between the medium pressure receiver and the second pressure reduction unit, to inject the part of refrigerant into a compression chamber of the compressor, and has a third expansion valve and an internal heat exchanger for carrying out heat exchange between the refrigerant whose pressure is reduced by the third expansion valve and the refrigerant between the medium pressure receiver and the second expansion valve, a pressure detection sensor for detecting a condensing pressure, and a controller for starting an injection control by the third expansion valve at the time when the condensing pressure detected by the pressure sensor or the condensing temperature calculated from the condensing pressure becomes a first predetermined value or more and stopping the injection control at the time when the condensing pressure or the condensing temperature becomes a second predetermined value which is smaller than the first predetermined value, or less. With this arrangement, an appropriate injection control can be realized and a high hot water supply/heating capability operation can be carried out.

摘要翻译： 在压缩机，水热交换器，第一膨胀阀，中压容器，第二膨胀阀和空气热交换器中的热泵式热水供给室外装置循环地连接，具有注入回路 用于中压受压器和第二减压单元之间的制冷剂的一部分的旁路，以将制冷剂的一部分注入到压缩机的压缩室中，并具有用于进行热交换的第三膨胀阀和内部热交换器 在通过第三膨胀阀减压的制冷剂与介质压力容器和第二膨胀阀之间的制冷剂之间，用于检测冷凝压力的压力检测传感器和用于通过第三膨胀阀开始喷射控制的控制器 由压力传感器检测到的冷凝压力或从冷凝预先计算的冷凝温度的时间 ssure成为第一预定值以上，并且在冷凝压力或冷凝温度成为小于第一规定值以下的第二规定值时停止喷射控制。 通过这种布置，可以实现适当的喷射控制，并且可以执行高热水供应/加热能力操作。

公开(公告)号：US20110079040A1

公开(公告)日：2011-04-07

申请号：US12995749

申请日：2009-06-12

申请人： Hiroyuki Morimoto ,  Kazuki Okada ,  Tetsuji Saikusa

发明人： Hiroyuki Morimoto ,  Kazuki Okada ,  Tetsuji Saikusa

IPC分类号： F25B43/00 ,  F25B1/00 ,  F25B29/00

CPC分类号： F25B43/003 ,  F25B43/043 ,  F25B2500/01

摘要： A compressor 1 for compressing a refrigerant containing a hydrofluoroolefin refrigerant, a condenser 2 for condensing the refrigerant by heat exchange, a throttle device 4 for decompressing the condensed refrigerant, an evaporator 5 for evaporating the refrigerant by heat exchange between the decompressed refrigerant and air, and air adsorbing means 3 for adsorbing oxygen and nitrogen are connected by piping so as to configure a refrigerant circuit through which the refrigerant containing the hydrofluoroolefin refrigerant is circulated.

摘要翻译： 用于压缩含有氢氟烯烃制冷剂的制冷剂的压缩机1，通过热交换冷凝制冷剂的冷凝器2，用于使冷凝的制冷剂减压的节流装置4，用于通过减压制冷剂与空气之间的热交换来蒸发制冷剂的蒸发器5， 用于吸附氧气和氮气的空气吸附装置3通过管道连接，以便构成制冷剂回路，使包含氢氟烯烃制冷剂的制冷剂通过该循环。

公开(公告)号：US06372943B1

公开(公告)日：2002-04-16

申请号：US09623475

申请日：2000-10-30

申请人： Shinobu Kasuga ,  Toshihito Kakiuchi ,  Ryo Yamanishi ,  Kazuki Okada

发明人： Shinobu Kasuga ,  Toshihito Kakiuchi ,  Ryo Yamanishi ,  Kazuki Okada

IPC分类号： C07C5702

CPC分类号： A61K8/362 ,  A61Q19/00 ,  B01F17/0021 ,  B01F17/0028 ,  B01F17/0042 ,  B01F17/005 ,  C04B24/04 ,  C04B2103/408 ,  C07C57/02 ,  C07D307/60 ,  C11D3/2082

摘要： Polyenepolycarboxylic acids represented by the following formula (1); (wherein n represents an integer of 0 to 5 and m represents an integer of 1 or 2, provided m is 1 when n is 0), or derivatives thereof at their carboxyl group(s) or their salts. The above compounds originate from natural products and are capable of exhibiting excellent dispersing ability.

摘要翻译： 由下式（1）表示的多元多元羧酸（其中，n表示0〜5的整数，m表示1或2的整数，n为0时m为1）或其衍生物 ）或其盐。上述化合物来自天然产物，并且能够表现出优异的分散能力。

公开(公告)号：US08733118B2

公开(公告)日：2014-05-27

申请号：US12360456

申请日：2009-01-27

申请人： Takahiro Ushijima ,  Kazuki Okada

发明人： Takahiro Ushijima ,  Kazuki Okada

IPC分类号： F25B27/00

CPC分类号： F25B30/02 ,  F25B1/10 ,  F25B13/00 ,  F25B2339/047 ,  F25B2400/053 ,  F25B2400/13 ,  F25B2400/16

摘要： To provide a heat pump water heater outdoor unit and heat pump water heater capable of preventing reduction in heating/hot water supply ability even at a low ambient temperature. A heat pump water heater outdoor unit, in which a compressor, a water heat exchanger, a first expansion valve, and an air heat exchanger are connected with piping, includes a first internal heat exchanger provided between the water heat exchanger and the first expansion valve and used for heat exchange between a refrigerant flowing between the water heat exchanger and the first expansion valve and a refrigerant flowing between the air heat exchanger and the compressor, an injection circuit branching off at a point between the first internal heat exchanger and the first expansion valve and to inject the refrigerant into the compressor through a second expansion valve; and a second internal heat exchanger for heat exchange between the refrigerant flowing between the first internal heat exchanger and the first expansion valve and the refrigerant flowing between the second expansion valve and the compressor in the injection circuit.

摘要翻译： 提供即使在低环境温度下也能够防止加热/热水供应能力降低的热泵热水器室外机和热泵热水器。 其中压缩机，水热交换器，第一膨胀阀和空气热交换器与管道连接的热泵热水器室外机包括设置在水热交换器和第一膨胀阀之间的第一内部热交换器 并且用于在水热交换器和第一膨胀阀之间流动的制冷剂与在空气热交换器和压缩机之间流动的制冷剂之间的热交换，在第一内部热交换器与第一膨胀之间的点分支的注入回路 并通过第二膨胀阀将制冷剂注入压缩机; 以及第二内部热交换器，用于在第一内部热交换器和第一膨胀阀之间流动的制冷剂与在注入回路中在第二膨胀阀和压缩机之间流动的制冷剂之间进行热交换。

公开(公告)号：US20090199581A1

公开(公告)日：2009-08-13

申请号：US12360456

申请日：2009-01-27

申请人： Takahiro Ushijima ,  Kazuki Okada

发明人： Takahiro Ushijima ,  Kazuki Okada

IPC分类号： F25B27/00 ,  F25B13/00

CPC分类号： F25B30/02 ,  F25B1/10 ,  F25B13/00 ,  F25B2339/047 ,  F25B2400/053 ,  F25B2400/13 ,  F25B2400/16

摘要： To provide a heat pump water heater outdoor unit and heat pump water heater capable of preventing reduction in heating/hot water supply ability even at a low ambient temperature. A heat pump water heater outdoor unit, in which a compressor, a water heat exchanger, a first expansion valve, and an air heat exchanger are connected with piping, includes a first internal heat exchanger provided between the water heat exchanger and the first expansion valve and used for heat exchange between a refrigerant flowing between the water heat exchanger and the first expansion valve and a refrigerant flowing between the air heat exchanger and the compressor, an injection circuit branching off at a point between the first internal heat exchanger and the first expansion valve and to inject the refrigerant into the compressor through a second expansion valve; and a second internal heat exchanger for heat exchange between the refrigerant flowing between the first internal heat exchanger and the first expansion valve and the refrigerant flowing between the second expansion valve and the compressor in the injection circuit.

摘要翻译： 提供即使在低环境温度下也能够防止加热/热水供应能力降低的热泵热水器室外机和热泵热水器。 其中压缩机，水热交换器，第一膨胀阀和空气热交换器与管道连接的热泵热水器室外机包括设置在水热交换器和第一膨胀阀之间的第一内部热交换器 并且用于在水热交换器和第一膨胀阀之间流动的制冷剂与在空气热交换器和压缩机之间流动的制冷剂之间的热交换，在第一内部热交换器与第一膨胀之间的点分支的注入回路 并通过第二膨胀阀将制冷剂注入压缩机; 以及第二内部热交换器，用于在第一内部热交换器和第一膨胀阀之间流动的制冷剂与在注入回路中在第二膨胀阀和压缩机之间流动的制冷剂之间进行热交换。

公开(公告)号：US06238148B1

公开(公告)日：2001-05-29

申请号：US09256218

申请日：1999-02-24

申请人： Toshiyuki Taniuchi ,  Kazuki Okada ,  Kazuhiro Akiyama

发明人： Toshiyuki Taniuchi ,  Kazuki Okada ,  Kazuhiro Akiyama

IPC分类号： C22C2900

CPC分类号： C22C29/08 ,  B22F2005/001 ,  B22F2998/00 ,  C22C1/055 ,  Y10T407/26 ,  Y10T407/27 ,  B22F1/0011 ,  B22F1/0018

摘要： In a cemented carbide cutting tool made of a tungsten carbide-based alloy comprising 8 to 13 percent by weight of Co and 0.1 to 3 percent by weight of Cr as constituents for forming a binding phase, the balance being tungsten carbide as a constituent for forming a dispersing phase and incidental impurities, the rate of the dispersing phase to the total of the dispersing phase and the binding phase being in a range of 72 to 90 percent by area and the average particle diameter being 1 &mgr;m or less according to measurement of an electron microscopic texture; the dispersing phase of the cemented carbide cutting tool made of a tungsten carbide-based alloy comprises a dispersing phase composed of ultra-fine particles dispersed in a matrix and having a particle diameter of 100 nm or less, and the ultra-fine particles comprise a Co based alloy.

摘要翻译： 在由碳化钨基合金制成的硬质合金切削工具中，包含8〜13重量％的Co和0.1〜3重量％的Cr作为形成结合相的成分，余量为碳化钨作为成型用成分 分散相和附带杂质，分散相与分散相的总量和结合相的比例在72〜90％的范围内，平均粒径为1μm以下，根据 电子显微纹理; 由碳化钨基合金制成的硬质合金切削工具的分散相包括由分散在基体中的粒径为100nm以下的超细粒子构成的分散相，超细粒子包含 Co基合金。

公开(公告)号：US20120111042A1

公开(公告)日：2012-05-10

申请号：US13384680

申请日：2010-01-15

申请人： Mamoru Hamada ,  Fumitake Unezaki ,  Yoshihiro Takahashi ,  Kengo Takahashi ,  Kazuki Okada ,  Hirokazu Minamisako ,  Shinichi Uchino

发明人： Mamoru Hamada ,  Fumitake Unezaki ,  Yoshihiro Takahashi ,  Kengo Takahashi ,  Kazuki Okada ,  Hirokazu Minamisako ,  Shinichi Uchino

IPC分类号： F25B49/00

CPC分类号： F25B47/025 ,  F24F11/41 ,  F25B13/00 ,  F25B49/02 ,  F25B2400/0411 ,  F25B2600/01 ,  F25B2600/021 ,  F25B2600/2501 ,  F25B2600/2513 ,  F25B2600/2521 ,  F25B2700/21151 ,  F25B2700/21163 ,  Y02B30/741

摘要： In a heat pump apparatus, it is aimed to enhance efficiency of a defrost operation by reducing a loss of heat radiation during the defrost operation and reducing a compressor input during the defrost operation. The heat pump apparatus includes a main refrigerant circuit in which a compressor, a first heat exchanger, an expansion mechanism, and a second heat exchanger are connected sequentially, and also includes a bypass circuit including an on-off valve and providing a connection by bypassing the expansion mechanism. The main refrigerant circuit includes a four-way valve that switches between a heating operation and the defrost operation by switching an order in which the refrigerant circulates through the main refrigerant circuit. The main refrigerant circuit also includes a first temperature detection unit and a second temperature detection unit. Based on values detected by these temperature detection units, a degree of superheat of the first heat exchanger during the defrost operation is computed. When the heating operation is switched to the defrost operation, the heat pump apparatus increases a circulation amount of the refrigerant circulating through the refrigerant circuit by opening the on-off valve, and also controls an operation frequency of the compressor such that the degree of superheat is at a predetermined target value.

摘要翻译： 在热泵装置中，旨在通过减少除霜操作期间的热辐射损失来提高除霜操作的效率，并且在除霜操作期间减少压缩机输入。 热泵装置包括：主制冷剂回路，其中压缩机，第一热交换器，膨胀机构和第二热交换器依次连接，并且还包括旁通回路，旁路回路包括开关阀，并通过旁路提供连接 扩张机制。 主制冷剂回路包括四通阀，其通过切换制冷剂通过主制冷剂回路循环的顺序而在加热操作和除霜操作之间切换。 主制冷剂回路还包括第一温度检测单元和第二温度检测单元。 基于这些温度检测单元检测出的值，算出除霜运转时的第一热交换器的过热度。 当加热操作切换到除霜操作时，热泵装置通过打开开关阀来增加通过制冷剂回路循环的制冷剂的循环量，并且还控制压缩机的操作频率使得过热度 处于预定的目标值。