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22 条记录 (耗时 0.014 秒)

    Preparation of anticancer-active tricyclic compounds via alkyne coupling reaction
    1.
    发明授权
    Preparation of anticancer-active tricyclic compounds via alkyne coupling reaction 有权
    通过炔炔偶联反应制备抗癌活性三环化合物

    公开(公告)号：US08703979B2

    公开(公告)日：2014-04-22

    申请号：US13190799

    申请日：2011-07-26

    申请人： Akira Iida ,  Kazunori Ueda ,  Mitsuaki Yamashita

    发明人： Akira Iida ,  Kazunori Ueda ,  Mitsuaki Yamashita

    IPC分类号： C07D307/92 ,  A61K31/343

    CPC分类号： C07D307/92 ,  A61K31/343 ,  C07D209/60

    摘要： The present invention is directed to provide a novel preparation of anticancer-active tricyclic compounds via alkyne coupling reaction. The present invention provides a process for preparing a compound of formula (Ia) or (Ib): wherein R1 is optionally substituted C1-6 alkyl, etc.; W is O, S or NR2; R2 is hydrogen atom, etc., which comprises Step (a) in which a compound of formula (II): wherein R1 is the same as defined above, and a compound of formula (III) or (IV): wherein R2 is the same as defined above; R3 is hydrogen atom, etc.; X is halogen atom, etc., are reacted in the presence of a base, a copper catalyst and a palladium catalyst in an aprotic polar solvent.

    摘要翻译： 本发明旨在通过炔炔偶联反应提供抗癌活性三环化合物的新型制备方法。 本发明提供了制备式（Ia）或（Ib）化合物的方法：其中R 1为任选取代的C 1-6烷基等; W是O，S或NR2; R 2是氢原子等，其包括步骤（a），其中式（II）化合物：其中R1与上述定义相同，和式（III）或（IV）化合物：其中R2是 与上述相同; R3是氢原子等; X是卤原子等，在碱性，铜催化剂和钯催化剂的存在下在非质子极性溶剂中反应。

    Liquid-crystal polyester resin
    3.
    发明授权
    Liquid-crystal polyester resin 有权
    液晶聚酯树脂

    公开(公告)号：US06984712B2

    公开(公告)日：2006-01-10

    申请号：US10496490

    申请日：2002-11-25

    申请人： Ryuzo Ueno ,  Masaya Kitayama ,  Kiichi Kometani ,  Hiroyuki Kato ,  Kazunori Ueda

    发明人： Ryuzo Ueno ,  Masaya Kitayama ,  Kiichi Kometani ,  Hiroyuki Kato ,  Kazunori Ueda

    IPC分类号： C08G63/06 ,  C08F20/00 ,  C09K19/32

    CPC分类号： C08G63/605 ,  C08G63/06 ,  C08G63/19 ,  C08G63/20 ,  C09K19/3809

    摘要： The present invention provides a liquid-crystalline polyester resin which comprises monomer units derived from 2-hydroxy-3-naphthoic acid and/or 2-hydroxynaphthalene-3,6-dicarboxylic acid in an amount of 1-5000 mmol % based on the total monomer components of the resin and an alkaline metal compound in an amount of 10-3000 ppm as alkaline metal based on the total monomer components of the resin. The liquid-crystalline polyester resin of the present invention has good colorability, improved heat resistance and good mechanical properties.

    摘要翻译： 本发明提供一种液晶聚酯树脂，其包含基于总量为1-5000mmol％的来源于2-羟基-3-萘甲酸和/或2-羟基萘-3,6-二羧酸的单体单元 树脂的单体组分和碱金属化合物，其量为基于树脂总单体成分的碱金属为10-3000ppm。 本发明的液晶聚酯树脂具有良好的着色性，耐热性和良好的机械性能。

    NOVEL PREPARATION OF ANTICANCER-ACTIVE TRICYCLIC COMPOUNDS VIA ALKYNE COUPLING REACTION
    6.
    发明申请
    NOVEL PREPARATION OF ANTICANCER-ACTIVE TRICYCLIC COMPOUNDS VIA ALKYNE COUPLING REACTION 有权
    通过烷基偶联反应制备新型活性三聚体化合物

    公开(公告)号：US20120077986A1

    公开(公告)日：2012-03-29

    申请号：US13190799

    申请日：2011-07-26

    申请人： Akira IIDA ,  Kazunori UEDA ,  Mitsuaki YAMASHITA

    发明人： Akira IIDA ,  Kazunori UEDA ,  Mitsuaki YAMASHITA

    IPC分类号： C07D209/60 ,  C07D333/74 ,  C07D307/78 ,  C07C211/48 ,  C07C49/747 ,  C07D405/04 ,  C07D409/04 ,  C07D307/92

    CPC分类号： C07D307/92 ,  A61K31/343 ,  C07D209/60

    摘要： The present invention is directed to provide a novel preparation of anticancer-active tricyclic compounds via alkyne coupling reaction. The present invention provides a process for preparing a compound of formula (Ia) or (Ib): wherein R1 is optionally substituted C1-6 alkyl, etc.; W is O, S or NR2; R2 is hydrogen atom, etc., which comprises Step (a) in which a compound of formula (II): wherein R1 is the same as defined above, and a compound of formula (III) or (IV): wherein R2 is the same as defined above; R3 is hydrogen atom, etc.; X is halogen atom, etc., are reacted in the presence of a base, a copper catalyst and a palladium catalyst in an aprotic polar solvent.

    摘要翻译： 本发明旨在通过炔炔偶联反应提供抗癌活性三环化合物的新型制备方法。 本发明提供了制备式（Ia）或（Ib）化合物的方法：其中R 1为任选取代的C 1-6烷基等; W是O，S或NR2; R 2是氢原子等，其包括步骤（a），其中式（II）化合物：其中R1与上述定义相同，和式（III）或（IV）化合物：其中R2是 与上述相同; R3是氢原子等; X是卤原子等，在碱性，铜催化剂和钯催化剂的存在下在非质子极性溶剂中反应。

    Cast slab surface temperature measuring device used in continuous casting machine
    7.
    发明授权
    Cast slab surface temperature measuring device used in continuous casting machine 有权
    铸坯表面温度测量装置用于连铸机

    公开(公告)号：US08888363B2

    公开(公告)日：2014-11-18

    申请号：US13984377

    申请日：2012-02-14

    申请人： Kazunori Ueda ,  Takeshi Okawa ,  Shinichi Fukunaga

    发明人： Kazunori Ueda ,  Takeshi Okawa ,  Shinichi Fukunaga

    IPC分类号： G01J5/00 ,  G01K1/00 ,  G01N3/00 ,  B22D11/18 ,  G01J5/02 ,  B22D11/20

    CPC分类号： G01J5/02 ,  B22D11/182 ,  B22D11/202

    摘要： A temperature measuring device, which is used in a continuous casting machine, measures the surface temperature of a part or all of a cast slab in a width direction of the cast slab, which is drawn from a mold and conveyed by rollers, in a secondary cooling zone of the continuous casting machine. The temperature measuring device includes a support member that is installed on the side of roller support parts by which the rollers are rotatably supported; an arm member of which a proximal portion is rotatably mounted on the support member; and a radiation thermometer which is provided at a distal end portion of the arm member and of which a light receiving opening is disposed at a position corresponding to a height in the range of 1.0 to 4.5 m from the surface of the cast slab.

    摘要翻译： 在连续铸造机中使用的温度测量装置测量从模具拉出并由辊输送的铸坯的宽度方向上的铸坯的一部分或全部的表面温度在次级 连铸机冷却区。 所述温度测量装置包括：支撑部件，其安装在所述辊支撑部分的侧面上，所述辊可旋转地支撑; 臂构件，其近端部分可旋转地安装在支撑构件上; 以及辐射体温计，其设置在所述臂部件的前端部，并且在与所述铸坯的表面相对应的高度为1.0〜4.5μm的位置处设置有光接收口。