公开(公告)号：US07902173B2

公开(公告)日：2011-03-08

申请号：US11363174

申请日：2006-02-28

Applicant: Naoyuki Yoshida ,  Kazushi Ishida ,  Shuji Sasaki ,  Takuo Ikeda ,  Jun Hiraki ,  Shigeyuki Aoyama

Inventor： Naoyuki Yoshida ,  Kazushi Ishida ,  Shuji Sasaki ,  Takuo Ikeda ,  Jun Hiraki ,  Shigeyuki Aoyama

IPC: A01N43/04 ,  A61K31/715

CPC classification number: C08B5/14 ,  A61K8/731 ,  A61Q19/00 ,  Y10S514/861 ,  Y10S514/863

Abstract: The present invention provides a compound selected from sulfated cellulose and salts thereof which can be used as an active ingredient for a cutaneous external preparation produced intending to prevent, soften, improve or cure atopic cutaneous symptoms and the like and which are excellent in a hydrolytic resistance, and dermatitis therapeutic agents and cosmetics using the same.

Abstract translation: 本发明提供一种选自硫酸纤维素及其盐的化合物，其可用作预防，软化，改善或治愈特应性皮肤症状等的皮肤外用制剂的活性成分，并且其耐水解性优异 ，以及使用其的皮炎治疗剂和化妆品。

公开(公告)号：US20080220033A1

公开(公告)日：2008-09-11

申请号：US12073675

申请日：2008-03-07

Applicant: Naoyuki Yoshida ,  Kazushi Ishida ,  Akiko Yoda

Inventor： Naoyuki Yoshida ,  Kazushi Ishida ,  Akiko Yoda

IPC: A61K9/16 ,  A61Q99/00

CPC classification number: A61K8/731 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/10 ,  A61Q1/12

Abstract: The invention provides a cosmetic ingredient and cosmetic compositions containing the same that exhibit skin protection/recovery properties and which are suitable for use in various cosmetic forms, such as skin care cosmetics, makeup cosmetics and skin cleansing agents. The cosmetic ingredient and cosmetic compositions containing the same include spherical sulfated cellulose or a salt thereof prepared by sulfate esterification of a part of the hydroxy groups of spherical cellulose.

Abstract translation: 本发明提供含有其具有皮肤保护/恢复性能并且适合用于各种化妆品形式的化妆品成分和化妆品组合物，例如护肤化妆品，化妆化妆品和皮肤清洁剂。 含有它们的化妆品成分和化妆品组合物包括通过一部分球形纤维素的羟基的硫酸酯化制备的球形硫酸纤维素或其盐。

公开(公告)号：US20070049746A1

公开(公告)日：2007-03-01

申请号：US11513110

申请日：2006-08-31

Applicant: Naoyuki Yoshida ,  Kazushi Ishida

Inventor： Naoyuki Yoshida ,  Kazushi Ishida

IPC: C08B13/00

CPC classification number: B01J20/286 ,  B01D15/3804 ,  B01J20/26 ,  B01J20/262 ,  B01J20/265 ,  B01J20/28019 ,  C08B5/14

Abstract: The invention provides spherical sulfated cellulose which has a high sulfur content and which is excellent for adsorbing proteins, a production process for the same, a protein adsorbing agent containing the above spherical sulfated cellulose and a chromatography apparatus using the same for a filler. More specifically, the invention provides a process for producing spherical sulfated cellulose comprising a step in which spherical cellulose is subjected to at least one sulfate esterification treatment with a mixture of N,N-dimethylformamide and sulfuric anhydride.

Abstract translation: 本发明提供了具有高硫含量，对于吸附蛋白质，其制备方法，含有上述球形硫酸化纤维素的蛋白质吸附剂和使用该球形硫酸纤维素的色谱装置的球形硫酸纤维素。 更具体地，本发明提供了一种制备球形硫酸纤维素的方法，其包括使用N，N-二甲基甲酰胺和硫酸酐的混合物对球形纤维素进行至少一种硫酸酯酯化处理的步骤。

公开(公告)号：US5895924A

公开(公告)日：1999-04-20

申请号：US602350

申请日：1996-02-16

Applicant: Hiroshi Yasuda ,  Akio Yamada ,  Kazushi Ishida ,  Tohru Ikeda ,  Kouzi Takahata

Inventor： Hiroshi Yasuda ,  Akio Yamada ,  Kazushi Ishida ,  Tohru Ikeda ,  Kouzi Takahata

IPC: H01L21/027 ,  H01J37/317 ,  H01J37/00

CPC classification number: B82Y10/00 ,  B82Y40/00 ,  H01J37/3174 ,  H01J2237/30455 ,  H01J2237/31761 ,  H01J2237/31774

Abstract: A charged particle beam exposure method is adapted to an exposure apparatus which includes a plurality of exposure systems that simultaneously expose the same pattern. The method includes the steps of (a) generating, by a pattern generating unit in each exposure system, data related to patterns which are to be exposed, (b) deflecting, by a column unit in each exposure system, a charged particle beam onto an object which is mounted on a stage by deflecting the charged particle beam based on the data generated by the pattern generating unit in a corresponding exposure system, and (c) detecting an abnormality in the exposure apparatus during operation of the exposure apparatus based on data which are obtained from corresponding parts of the exposure systems.

Abstract translation: 带电粒子束曝光方法适用于包括同时暴露相同图案的多个曝光系统的曝光装置。 该方法包括以下步骤：（a）通过每个曝光系统中的图案生成单元生成与要曝光的图案相关的数据，（b）通过每个曝光系统中的列单元将带电粒子束偏转到 基于由对应的曝光系统中的图案生成单元产生的数据，通过使带电粒子束偏转来安装在舞台上的物体，以及（c）基于数据在曝光装置的操作期间检测曝光装置中的异常 其从曝光系统的相应部分获得。

公开(公告)号：US4803316A

公开(公告)日：1989-02-07

申请号：US919756

申请日：1986-10-16

Applicant: Kazutoshi Hayashi ,  Hideo Nabetani ,  Toshiaki Tanaka ,  Kazushi Ishida

Inventor： Kazutoshi Hayashi ,  Hideo Nabetani ,  Toshiaki Tanaka ,  Kazushi Ishida

IPC: H01H5/30 ,  H01H11/00 ,  H01H13/20 ,  H01H13/50 ,  H01H13/807 ,  H01H5/18

CPC classification number: H01H13/807 ,  H01H13/20 ,  H01H11/0056 ,  H01H13/50 ,  H01H2215/036 ,  H01H2221/064 ,  H01H2225/028 ,  H01H2237/002 ,  H01H5/30

Abstract: A push button switch employing a dome spring switch element mounted in a vertical orientation relative to a generally horizontal orientation of a bottom support plate, and a key top and associated plunger which are mounted for limited, reciprocating vertical movement. An actuator, comprising a coil spring and a pivotally mounted lever, interconnects the plunger and the spring dome and is responsive to and converts vertical downward movement of the plunger to a horizontally directed depressing force on the dome spring for inverting the dome spring in a snap action and completing an electrical connection between inner and outer contacts mounted within the switch element and underlying the dome spring. A dome spring of rectangualr shape affords improved force versus displacement and snap action characteristics, and a contact frame providing flexible support of the inner contacts reduces impact shock and wear produced by the snap action. A locking structure provides for locked interengagement of the key top and plunger and a stepped, flexible stop absorbs shock and reduces impact noise in stopping the return movement of the plunger from a depressed to a normal condition. A direct drive connection between the plunger and the lever reduces the amount of plunger movement and depression force required to actuate the switch under abnormal load conditions. A process for fabrication of the switch element by stamping and molding steps reduces costs and improves reliability of the switch element.

Abstract translation: 一种按钮开关，其采用圆顶弹簧开关元件，该圆顶弹簧开关元件相对于底部支撑板的大体上水平的方向以垂直方向安装，以及键顶和相关联的柱塞，其被安装用于有限的往复垂直运动。 包括螺旋弹簧和可枢转地安装的杠杆的致动器将柱塞和弹簧拱顶相互连接，并且响应并将柱塞的垂直向下运动转换成圆顶弹簧上的水平方向的下压力，以便以卡扣方式翻转圆顶弹簧 动作并完成安装在开关元件内部和下面的穹顶弹簧的内部和外部触头之间的电连接。 整体形状的圆顶弹簧提供改善的力与位移和卡扣动作特性，并且提供内部触点的柔性支撑的触点框架减少了由快动作用产生的冲击冲击和磨损。 锁定结构提供了键顶和柱塞的锁定相互接合，并且阶梯式柔性止动件吸收冲击并减少冲击噪声，以阻止柱塞从凹陷到正常状态的返回运动。 柱塞和杠杆之间的直接驱动连接减少了在异常负载条件下启动开关所需的柱塞运动和压下力。 通过冲压和成型步骤制造开关元件的工艺降低了成本并提高了开关元件的可靠性。

公开(公告)号：US20100324280A1

公开(公告)日：2010-12-23

申请号：US12521525

申请日：2007-12-26

Applicant: Ippei Yamaoka ,  Naoyuki Yoshida ,  Kazushi Ishida ,  Shuji Sasaki

Inventor： Ippei Yamaoka ,  Naoyuki Yoshida ,  Kazushi Ishida ,  Shuji Sasaki

IPC: C07H15/04

CPC classification number: A61K31/717 ,  C08B5/14 ,  C08B11/10 ,  C08B15/005 ,  C08L1/16 ,  C08L1/284

Abstract: The present invention provides a sodium absorption inhibitor, a potassium absorption inhibitor, and a phosphorus absorption inhibitor, and a preventive agent, a therapeutic agent and a food for diseases caused by overconsumption of common salt, potassium and phosphorus or diseases which require restriction of ingestion of common salt, potassium and phosphorus to actively and safely excrete overconsumed common salt, potassium and phosphorus excreted outside the body. R—O-A   (I) {In the formula (I), R represents a crosslinked cellulose residue and A represents a functional group a having cation-exchange ability.}

Abstract translation: 本发明提供了一种钠吸收抑制剂，钾吸收抑制剂和磷吸收抑制剂，以及预防药物，治疗剂和由食盐过多，钾和磷引起的疾病或需要限制摄取的疾病的食物。 的普通盐，钾和磷，以积极和安全地排泄体外过量消耗的普通盐，钾和磷。 R-O-A（I）{式（I）中，R表示交联纤维素残基，A表示具有阳离子交换能力的官能团。

公开(公告)号：US5708276A

公开(公告)日：1998-01-13

申请号：US600456

申请日：1996-02-13

Applicant: Tatsuro Ohkawa ,  Kawakami Kenichi ,  Yoshihisa Ooae ,  Tohru Ikeda ,  Kazushi Ishida

Inventor： Tatsuro Ohkawa ,  Kawakami Kenichi ,  Yoshihisa Ooae ,  Tohru Ikeda ,  Kazushi Ishida

IPC: G01B15/00 ,  G03F7/20 ,  G03F9/00 ,  H01J37/304 ,  H01J37/305 ,  H01L21/027

CPC classification number: H01J37/3045 ,  H01J2237/24495 ,  H01J2237/30438

Abstract: An electron-beam exposure device having at least one deflector for deflecting an electron beam and detecting a position of a position-detection mark with the electron beam includes a plurality of detectors detecting electrons scattered from the position-detection mark, a plurality of amplifiers, each of the amplifiers amplifying an output of a corresponding one of the detectors, and a setting unit for setting amplification factors of the amplifiers such that a magnitude of an output from each of the amplifiers is constant irrespective of a deflected position of the electron beam at a time of detection of the position of the position-detection mark.

Abstract translation: 具有用于偏转电子束的至少一个偏转器和用电子束检测位置检测标记的位置的电子束曝光装置包括检测从位置检测标记散射的电子的多个检测器，多个放大器， 每个放大器放大对应的一个检测器的输出，以及设置单元，用于设置放大器的放大因子，使得来自每个放大器的输出的幅度恒定，而与电子束的偏转位置无关 检测位置检测标记的位置的时间。

公开(公告)号：US6046459A

公开(公告)日：2000-04-04

申请号：US401943

申请日：1999-09-23

Applicant: Nobuyuki Yasutake ,  Yoshihisa Ooae ,  Kazushi Ishida ,  Hiroshi Yasuda ,  Akiyoshi Tsuda ,  Hitoshi Tanaka

Inventor： Nobuyuki Yasutake ,  Yoshihisa Ooae ,  Kazushi Ishida ,  Hiroshi Yasuda ,  Akiyoshi Tsuda ,  Hitoshi Tanaka

IPC: G03F7/20 ,  H01J37/317 ,  H01J37/20

CPC classification number: B82Y10/00 ,  B82Y40/00 ,  G03F7/2037 ,  G03F7/2065 ,  H01J37/3174 ,  H01J2237/31774

Abstract: With using one scanning stage 19 where a plurality of wafers 16A to 16E is mounted through wafer holders 20A to 20E and balancing stage 21 disposed below scanning stage 19, scanning stage 19 is scanned based on exposure data common to a plurality of charged particle beam exposure apparatus 10A to 10E, and balancing stage 21 is scanned so that barycenter G of scanning stage 19 and balancing stage 21 becomes a fixed point. The positions of reflecting mirrors 70L and 70R secured to stage 19 are measured and based on their values, the expansion/contraction ratio of stage 19 and the positions of samples 16A to 16E are calculated to obtain deviation of the positions from target positions. Stage 19 is modeled such that rigid areas 19A to 19E are loosely connected, and for each area, the positions of three points are measured to calculate deviation of the exposure target position due to rotation of each ridged area. These deviations are corrected by deflectors 18A to 18D.

Abstract translation: 通过使用一个扫描台19，其中通过设置在扫描台19下方的晶片保持器20A至20E和平衡台21安装多个晶片16A至16E，基于多个带电粒子束曝光共同的曝光数据扫描扫描台19 扫描装置10A至10E以及平衡级21，使得扫描级19和平衡级21的重心G成为固定点。 测量固定在工作台19上的反射镜70L和70R的位置，并且基于它们的值，计算级19的伸缩比和样品16A至16E的位置以获得位置与目标位置的偏差。 阶段19被建模为刚性区域19A至19E松散地连接，并且对于每个区域，测量三个点的位置以计算由于每个脊状区域的旋转引起的曝光目标位置的偏差。 这些偏差由偏转器18A至18D校正。

公开(公告)号：US20100317844A1

公开(公告)日：2010-12-16

申请号：US12521524

申请日：2007-12-26

Applicant: Naoyuki Yoshida ,  Kazushi Ishida ,  Shuji Sasaki ,  Ippei Yamaoka

Inventor： Naoyuki Yoshida ,  Kazushi Ishida ,  Shuji Sasaki ,  Ippei Yamaoka

IPC: C07H23/00

CPC classification number: A61K31/717 ,  C08B5/00 ,  C08B11/12 ,  C08B15/005

Abstract: The invention provides a metal salt of a crosslinked cellulose derivative represented by the following formula (I), wherein the degree of substitution of the hydroxyl group of glucose unit of the crosslinked cellulose derivative by a functional group a is 1 or more. R—O-A  (I) {In the formula (I), R represents a crosslinked cellulose residue and A represents a functional group a having cation-exchange ability.}

Abstract translation: 本发明提供由下式（I）表示的交联纤维素衍生物的金属盐，其中交联的纤维素衍生物的官能团a的葡萄糖单元的羟基的取代度为1以上。 R-O-A（I）{式（I）中，R表示交联纤维素残基，A表示具有阳离子交换能力的官能团。

公开(公告)号：US20090247740A1

公开(公告)日：2009-10-01

申请号：US12434359

申请日：2009-05-01

Applicant: Naoyuki YOSHIDA ,  Kazushi ISHIDA

Inventor： Naoyuki YOSHIDA ,  Kazushi ISHIDA

IPC: C08B15/00

CPC classification number: B01J20/286 ,  B01D15/3804 ,  B01J20/26 ,  B01J20/262 ,  B01J20/265 ,  B01J20/28019 ,  C08B5/14

Abstract: The invention provides spherical sulfated cellulose which has a high sulfur content and which is excellent for adsorbing proteins, a production process for the same, a protein adsorbing agent containing the above spherical sulfated cellulose and a chromatography apparatus using the same for a filler. More specifically, the invention provides a process for producing spherical sulfated cellulose comprising a step in which spherical cellulose is subjected to at least one sulfate esterification treatment with a mixture of N,N-dimethylformamide and sulfuric anhydride.

Abstract translation: 本发明提供了具有高硫含量，对于吸附蛋白质，其制备方法，含有上述球形硫酸化纤维素的蛋白质吸附剂和使用该球形硫酸纤维素的色谱装置的球形硫酸纤维素。 更具体地，本发明提供了一种制备球形硫酸纤维素的方法，其包括使用N，N-二甲基甲酰胺和硫酸酐的混合物对球形纤维素进行至少一种硫酸酯酯化处理的步骤。